DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2469 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Birth Control Weight Gain, inability to loose weight, moody, no patience, lots of Acne, really dry scalp during all times of year, very tired all the time. I have been on Depo before this 5 month spurt, and before children I was able to be on it and gain about 10 lbs. Then loose it. After being on it after having 3 children its has stopped all periods which is a plus but, I have become really irritable, I have such oily hair now that I take small little pieces out of my hair, horrrible dry scalp, and no shampoo helps.. even the medicated doesn't help. I also have horrrible acne all the time, its as if I start to get a cleared up face, its time for the following shot and it starts all over again. I have also noticed that my libido has fallen a lot and I am always exhausted. Even on the days I do nothing. I have had a strict diet 1200 calories and I have still gained 25lbs in the last 5 months. I have now plateaued and still can not get below where I am. I have since gotten the Essure implantations put in and I am now only to be on it until June/July. Thank goodness. As a birth control it works wonders but the side effects are not worth it. F 29 5 months
1shot/3mon 1X O
3/4/2011
Email
 1  birth control Actually, it was my student. Two days after getting the shot, she appeared to be flying high on meth. She tested clean. By the next day, her behavior was bizarre. Her comments were completely out of context. She was taken to the doctor who thought it was from the Depo shot. She was admitted to a psychiatric facility for evaluation. She presented as bipolar and schizophrenic. She was paranoid and delusional. Doctors believe it was the depo shot that caused it. She was perfectly normal before the shot. Two days later she was completely bizarre. It is a horrible tragedy for this beautiful girl. (The age I put is hers) Her parents would like to hear from anyone with similar experience. Please email me. F 17 2 weeks
1X day
3/4/2011
Email
 1  regulate period, prevent pregnancy Weight gain, inability to lose weight even with extreme exercise and diet, headaches, nausea, depression, fatigue, changes in appetite (some days more some days less), spotting EVERYDAY, long light period or no period, totally absent sex drive, painful sex, acne, dizziness. I've tried my best to stay free of putting meds in my body but my very heavy period and extremely painful cramps made me disparate to regulate it. I didn't want the pill because I was working two jobs and going to school & knew I would not remember. My doc recomm Depo & I went for it not thinking much about the side-effects. Now I wish I had researched before getting my injection. Not a nice experience. I have been wondering why I was feeling all these things, why no sex drive, why painful sex for the first time in my life! Also feeling so sad and down if I have no reason to and why can't I lose weight if I am exercising like I'm in the military (not a single pound!!!!!) I know its because of this drug. This is why I didn't want to put anything in my body. This is a horrible medication and wish I could get it out of my body NOW! BUT I have to wait until its time for my next appointment so I can change my prescription. F 28 3 months
1X AN
3/3/2011
 2  To prevent pregnancy Inability to lose weight, even after diet and exercise-Extreme aggitation and irritability, decreased sex drive I got the Depo shot about 6 weeks ago after having a baby. I noticed at first, it was a little difficult to shed the baby weight. I didnt really have any other side effects until about a week ago. I, out of nowhere, have turned into a monster. I have no patience, Im very irritable, I cry over almost anything, and I become extremely aggitated very easily. I at first couldnt figure out where these feeling were coming from. I thought I had a new onset of depression, and did a little research and realized, after reading several different articles, that it might be the depo. I'm hoping it is the depo shot b/c I know soon it will be out of my system. I dont know how much longer I can take being on edge all the time. F 26 6 weeks
1X AN
3/2/2011
 1  birth control massive period, tired, NO patience, horrible mood swings, out of control hormones, no sex drive, uncontrollable crying... This seemed to be the only option that was going to be convenient for my life with a newborn - not having to remember to take it... It was HORRIBLE. My period continued into 60 days... Spotting then stopping then a PERIOD. I would cry with my son because I was such a basketcase... It was horrible and I will not get my 2nd dose of this...EVER. I would rather try and remember to take the pill. HORRIBLE. But I have heard of some ppl that actually like this - not side effects like these... F 22 3 months
1X day
3/1/2011
 1  Migraines, Cramping, Heavy bleeding I'm experience anything bad that could possibly happen. I often forget what I had just said or what I did 5 minutes earlier. I have hip pain and abdominal pain that's so intense it brings me to my knees. My hair is thinning out [I'm losing hair] and I have bled constantly for maybe 2 years. When I started reporting my symptoms to my Dr. he said another shot might help. [The shot only worked for me for about a year and half] So of course, him being your doctor, you trust him and do what he says. Since then my health has depleted considerably. Once an active teenager, [I'm 21 now, started when I was 16.] I started sleeping all the time and not wanting to move. I'd just lay in bed for days because moving, killed. So, since they figured it was the Depo, we did a series of other test that came back negative. Nothing was wrong with me, except for the strange synthetic pumping through my veins. I just quit Depo this year, and after reading all these comments I literally bawled. I feel bad for anyone who has suffered from this BC. After a CT scan they found a mass in my back on the left side, right behind my uterus/ovary. Months later and they still dont know what it is or even exactly where it's sitting. I DO NOT recommend this for anyone. It's supposed to stop bleeding. That's the glamour of it. None of us like bleeding really, but I've been bleeding for 2 years. Straight. I weigh 94 pounds and just get sicker and sicker. Please save yourself the pain and torture and just get the pill. F 21 5 years
30mg 1X AN
2/28/2011
Email
 1  Safer sex-no pregnancy too many to mention- a lot of fatigue please email me about your experience-especially if you feel better and how long that took. [email protected] F 18 75 days
150mg 1X O
2/27/2011
Email
 3  for painful menses and to avoid TAH If I have read all your comments, I would of avoid my experience. I went to a GYN, who told that for me to avoid having painful menses, I mean they were bad, and kept me at home, couldn't do anything, recommended plain hystectomy. then I decide to go to another dr, she told me I could try the pill,the one for breastfeeding women, and then go to Depo. I did ok with pill for a month, and got the shot, not for contracption, but for pain. it was good! no pain during 2 months, then..the last month, 2 wks prior do 2nd dose, I started feeling pain in my lower abdomen, constipation, and bleeding, BLACK and clotted. I called my dr, and she told that it was"old blood" from my uterus, asked me if I want the shot again, I said NO, the side effects are horrible, I feel depressed, not to mention knee pain (depo make you lose bone),gained weight, loss of libido for 3 months,my poor husband.. I mean I don't know how long is going to stay in my body, please if anyone has an idea let me know.t F 40 3 months
150mg 1X O
2/24/2011
Email
 1  Birth Control Decreased sex drive, Vaginal dryness, weight gain, and mood swings At first it was great. I could have sex without a condom and I was having a very normal sex life. But then maybe 2 months into the shot I started bleeding while I was having sex. But that only lasted a couple of weeks. Then my last couple of weeks with the drug in my system I started having painful sex. Well it wouldn't hurt at first because I would be wet but then after awhile I would dry up and not be able to get wet anymore. It was very irritating for me and my boyfriend because we had to keep using lube when before we hardly ever had to use it. Now I have been off the shot for 2 weeks and I am now starting to have really bad cramps and increased urination and constipation. My period also hasn't come and I'm wondering when it will. I'm really hoping my sex drive comes back as well. Anyway I wouldn't recommend this drug to anyone. F 19 3 months
Dk 1X AN
2/24/2011
 3  to prevent pregnancy inregular periods, bleeding for weeks,bloating,low sex drive,and anger i have been on depo for many years never had any side effects until after i had my son..maybe i need to swicth from the shot to the pill. F 20 6 years
1X O
2/23/2011
 1  Birth-Control Depression, anxiety, weight gain So I have hesitated to post this but I realize if I stay silent it will not benefit anyone. I had Depo-Provera injected into my body in 1994 after my first child and once the symptoms began I stopped taking it; basically I only received one dosage. However this is such a toxic medication that I suffer to this day with problems that were created by taking just that one dose. The best I have felt since then was when I was being treated by a Naturopathic Physician. She took the time to listen to EXACTLY what I was complaining about and then compared by complaints with my lab work and treated me accordingly. I thank God for her and for the treatment plan she placed me on. Depo was never mentioned and yet through her LISTENING she was able to hit the target. I was not 100% certain about the problems I have experienced since 1994 being related to the Depo until I found this website. Ladies there is EXTREME danger to your body now and way into the future if you take this drug. Figure out a better birth control method. F 42 3 months
Unkonwn 1X day
2/23/2011
Email
 4  Birth Control Odd periods, increased sex drive, crazy hormones, headaches, 3 lb. weight gain over 1 year, acne This last shot has been my worse, no idea why. Personally I believe the nurse just botched it up. But I have been on this shot for 1 year now. I have unprotected sex FREQUENTLY, and it most definitely works. My periods are a little off but until you realize you are NOT going to get pregnant, you'll stress about it. When my shot's wearing off is when I have the most symptoms. I get extra turned on by the smallest things, I get depressed sometimes and sort of needy, sometimes small little headaches. Once I get the shot, it's all cleared up! Besides the weight gain, which is caused by being hungry once you get the shot. Every time I get the shot I have to remember immediately afterwards I'm going to think I'm SO hungry, when in reality I should know I'm not. Monitor what you eat, people. It's not so hard. Depo DEFINITELY works. F 18 1 years
Average MG 1X AN
2/19/2011
 4  help stop my period to soothe ibs The only side effect I had was the spotting which wasn't that bad but it did last about a month. I was happy that I found a discrete form of birth control that was easy to remember! But I decided to go in another direction because, like always, I started doing my research and its suggested that you shouldn't take it for more than 2 years.So I switched to the patch, ortho evra. It'd be nice not to have a period but I'm willing to get a lighter one! F 20 3 months
1X O
2/19/2011
Email
 1  Painful periods (Endometriosis) Depression, memory loss, decrease in sex drive, anxiety, fatigue, painful joints, frequent urination, increase appetite, hair shedding, long heavy periods, pregnancy symptoms, mood swings, bloated stomach, dry skin, weight gain, etc. I feel like a lab rat, I am praying to God for this drug to be out of my system. I had one (3 month) injection and refuse to continue poisoning my body. I cannot believe the effects this medication have on my mood and body. I literally took a week off work because of anxiety, depression and fatigue. This drug is the devil. It has no place in the human body. I don't know which is worst... Depo or Lupron. Do not take this drug. It will create additional problems when trying to prevent pregnancies or painful periods. F 39 3 months
1X O
2/18/2011
 1  Birth Control Depression, Anxiety, Anger/Mood Swings, Insomnia It is 5 AM, and I'm exhausted but wide awake in fear. I have only been on this for FIVE days, and it is a nightmare! I got the shot w/ great enthusiasm that a birth control lasts 3 mo.. the last I was on was the ring 5 years ago. Also, I took emergency contraception, which the nurse said was a fine combo. When she was going over side effects, the only one which concerned me was the weight gain, but she said, all you have to do is control your eating, as if no big deal. I said I was on the ring before and a side effect was feeling a little emotional.. is this a side effect of this? She replied, well any time you alter your hormones in your body, it could affect that, but basically dismissed my fears and made it seem like that shouldn't be a concern at all! The day after the shot, I felt depressed, didn't leave my room all day, and cried twice.. I don't even know about what. The 3rd and 4th days, I experienced uncontrollable rage or snapping at people, all over minor things. I didn't even realize it at first either. I told two friends.. and also said I felt concerned enough I should go talk to the doctor by 4th day (I didn't cuz I thought I was still OK). (cont in next review) F 27 5 days
1X AN
2/17/2011
Email
 1  Birth Control see previous review, this is a continuation (cont) I have been eating UNCONTROLLABLY (although this side effect I can perhaps attribute to a placebo effect, as the nurse had mentioned it and I was concerned about it). I have gained a solid 6 pounds already, which is a HUGE change for me. It's not that I necessarily would say I feel hungry.. it's more that I can't stop eating because I feel stressed. Also, I noticed I was gradually sleeping less each night.. waking up earlier and earlier in the morning, but I didn't think it was insomnia or anything related to the shot. Now, on the fifth day, I experienced the same anger during the day. At around 12:30 am, I lay down to sleep. I can best describe the next 5 hours as a nightmare.. I felt unsettled and unnerved despite being exhausted from a long day. A million thoughts were anxiously racing through my mind and I couldn't stop worrying. Then, I had what I can best describe as a nightmare while awake- a sudden thought in my head of me driving a car into a bus at full speed. At that point, I felt terrified. My room is cold right now since it's winter, but I was getting hot flashes. I felt terrified, helpless and 'crazy.' Around 5 AM, I couldn't take it anymore and started Googling side effects of Depo-Provera. Knowing other people have these side effects, however, has not lessened how I feel right now.. if anything, I feel very scared and alone.. I suppose because the hormones are already in my body for at LEAST 3 months.. seems like it may be much longer th F 27 5 days
1X AN
2/17/2011
 1  Birth Control Normal periods until stopped getting shot. No period, painful, hair growth, weight gain, cramping, bloating. I was on the Depo for six months, maybe, I then got off of it cause I no longer needed it, but in the time I lost my period, then got it in 5 months, really painful, and then I lost it for half a year, but with the symptoms of an upcoming period. I do not recommend this, it's too high of a dosage right away, it will mess with your harmones. F 19 3 months
1X O
2/16/2011
 3  easy bc i was like a dead person, i was super tired all the time and was very apathetic. i never experience any bleeding and gain 3 or so pounds. My boobs increased in size by a whole cup and now that im off don't seem to be decreasing. i lost my period for those 9 months and i've been off it for two months now and im starting to wonder when my period will return? i've found that taking vitamins normally can help with the tiredness, im guessing from extra iron and calcium. gave it a 3 because i didn't get preggers so it helped, somewhat. i would say that this medicine is very extreme, and that there's a number of other ways to ensure not becoming preggers that are a lot safer. im worried about what my bone density loss means for my future and what has been mutated by this drug, if there's a higher risk for cancer. Save yourself the trouble and stick with something that effects your body less. im serious, Treat your body like a temple and leave this poison out of it F 20 9 months
?? 1X O
2/14/2011
Email
 1  painfull periods, birth control anxiety/panic attacks, irrational fears, low blood sugar, weight gain, hair loss, feel like losing it I posted here on 2/11/09.Here I am 2 yrs later with THE SAME HORRIBLE SIDE EFFECTS! In the 3 and a half yrs since the first panic attack I’ve seen all kinds of doctors and been on all kinds of meds: 2 GPs who shoved antidepressants and benzos down my throat, 1 endocrinologist who told me it was all in my head, 1 psychiatrist who blamed it on stress, 1 acupuncturist who took my $600 and he was happy, 1 homeopath who did not even follow up with me after one missed appointment. NOT ONE OF THESE IDIOTS CONNECTED THE DOTS and thought the Depo could have triggered the symptoms (they were all informed I was on it for over 2 years).Thousands of dollars down the drain, years of suffering,false hope,humiliation. My hormones are screwed up,I feel like I’m on a rollercoaster but can’t get off.Absolutely devastating.Who's going to give me back all these years of suffering,of not being able to go places by myself because of these irrational fears I NEVER HAD BEFORE?If thousands of women are still experiencing devastating symptoms and sites have been created to report them,why is the drug still out there?I read posts from the 1990s and here we are in 2011 and women are still poisoned.has a lawsuit ever been filed?We're voicing our pain and suffering ,"BIG PHARMA" and FDA are laughing at us, poor stupid women "genetically insane". I'm now in the compassionate hands of a naturopath.He's really my last resort before the madhouse. F 47 28 months
no idea 1X O
2/14/2011
Email
 5  Birth Control head ache, moodiness, extreme fatigue, back acne. I got the shot after coming off birth control pills. remembering to take the pill everyday was annoying so the shot is a great alternative. ive only been on the shot for a few weeks but haven't really experienced many extreme side effects. mainly just fatigue and my back broke out pretty bad. (which has NEVER happened to me before). after awhile though, my fatigue decreased as i became more adjusted to the shot and my back eventually cleared up (thank god!) Also noticed some decrease in sex drive. But, overall, the shot is a great alternative to those who have trouble remembering to take their daily birth control pill. F 19 4 weeks
3X O
2/13/2011

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