DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Endometriosis nauseau, constipation, occasional depression, joint pain, weight gain, fatigue, difficulty sleeping, loss of motivation, headaches, occasional mood swings, dizzyness, anxiety, extreme breast sensitivity, acne, spotting, low hemoglobin, hot flashes I have taken this for years to treat endometriosis because there are few other alternatives, I've had some of these symptoms for years and talked to my doctor about it but was assured it wasn't because of the medication. The more research I've done, the more I've come to realize most if not all of these symptoms are from the shot. Most of them seem to be worse not long after I get the shot and get a little shortly before I'm due for another. I still have a shot in my system but I will definitely be seeking another option afterward. I'm tired of feeling like this!! I wish I would have put all this together sooner and saved myself so much time of being so miserable. There are days when the brest senistivity is so extreme I can't stand the feeling of fabric on my skin. I will become so fatigued but I can't sleep. I've had constant problems with constipation and quite a bit of weight gain. I was on Depo Luprin (sp?) for a couple of years instead of Provera and the symptoms were quite a bit worse, to the point that I refused to take it any longer. That medication is used frequently for endometriosis. Make sure you do your home work before blindly taking a medication prescribed by your doctor. And listen to your body, you know you're body better than anyone else does!! F 29 6 years
30MG 1X M
7/18/2011
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 1  extremely heavy periods hair loss, acne, tearfulness, anger, sudden period cramps, increased sex drive, 4 month period got this for heavy periods, first 3 month cycle i spent the whole time crying, then upon getting second injection i had a heavy period for 4 months (haemoglobin went down to 7), it amplifies my negative moods a thousandfold. When I brush my hair, so much hair comes out it's a wonder i'm not bald. I keep getting spontaneous, agonizing womb cramps as if i'm going to have a period. I'm on my 4th jag now and all I want to do is hump things, i'm constantly horny. I haven't gained weight, rather I've lost it. I keep getting huge spots that I never had before I started. F 17 9 months
4X O
7/17/2011
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 2  To help with painful periods extreme fatigue, headaches 3 to 4 times a day, bloating, stomach pains, joint swelling and joint pain, confusion, and blurriness with eyes. I did not have these symptoms right away. It took about a year before they showed up. I was not sure it was the shot and went to my gyno first. She said the shot could not be giving me this trouble and sent me to a nuerologist. After many many test he could not help me. He as well said the shot was not the cause. I then went to a rheumatologist b/c of the joint issues. He too could not help. After researching the shot myself I then became convinced that I was having side effects from the shot. I just wish I had listened to my gut over a year ago when I started having trouble. I would not take a chance on using this drug. It is not worth it. F 35 2 years
1X O
7/15/2011
 4  Birth control - eliminate discharge None I use this for birth control, eliminate vaginal discharge and period. I have been using this for years and have been very happy with the results and had no side effects. F 38 6 years
150 1X O
7/14/2011
 1  To decrease my periods Extremely long heavy periods with blood clots. Broke out with itchy rash/hives on arms, back, neck and torso area at least 2 to 3 times a week. Mood swings and weight gain. Also lost sex drive and became very depressed. Depo basically ruined my life. I do not recommend Depo to anyone it is horrible. I went to my doctor and demanded to be put back on the pill. F 40 9 months
1X O
7/13/2011
 2  birth control n painful periods Hair lost, weight gain, increase appetiet, mood swings, fatigue..... I will not recommended to anyone. I have being taking it for 2 years n the first year was great. By the secound year I begun to notice hair lost, increse appetiet n milk comming out my brest. N lots more. I never stoped my period. My period was regular for 1 year but the secound i will last for 1 month. It is horrible. Right knw i am trying to loss the 20 lbs. I gain in 3 months n now im swiching to junel1-20 hopefully things get better. F 18 2 years
1X day
7/12/2011
 3  Pregnancy Prevention plus period re Bloating, weight loss, instead of heavy periods I have a little bit of blood mixed with a mild yeast infection (only a bit of itching) once the period is over the infection tends to go away. I get the shot every 3 months. I don't believe it is for everyone after reading the comments but It works for me I'm not responsible enough to remember to take the pill everyday so I get the three month shot and I'm good to go for awhile If your going to get the shot I don't recommend a long term one (meaning years) You cant be sure how your body will react. As for me It works well so I recommend it with caution. I have been getting the shot for over a year and I don't believe the side effects I have are bad. F 19 1.5 years
1X O
7/11/2011
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 3  Prevent Pregnancy Extreme Headaches, Dizzyness with Headaches, Swelling, Tired all the time, bad mood swings, depression, No motivation. F 21 45 days
1X M
7/9/2011
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 1  Stop pregnancy, period Extreme fatigue, constipation- no bowel movement for up to 5 days, mild depression, pain in joints (knees, fingers, wrist), loss of sex drive, vaginal dryness, bladder and abdominal pressure, constant thirst for pop and water, frequent urination, bloating- around waistline looked 6 months pregnant, bloated looking face, finger swelling, excessive body hair growth, body weakness, poor circulation- arms and shoulders numb upon waking, obsessive thoughts, extreme paranoia, increased acne on face chest and back, poor digestion, constant burping and heartburn, severe hot and cold flashes, mood swings (very angry never happy), blurry vision, overall body aches low back pain, hair dry and brittle, fingernails brittle, boil like cysts on buttocks and vagina, nervousness and anxiety. catch colds and sick constantly, shortness of breath, increased mucus in the throat. very hypoglycemic- get shaky, sweat and bottom out . Loss of interest in life and very antisocial and constant feeling if being i I would not recommend to anyone!!! I personally loved the shot for 10 plus years no side effects to think of except a little weight gain but was fine with that because I was very skinny. But the weight kept coming and I have gained 90 pounds so far. My major side effects started 10 years ago, but never made the connection to depo being the cause. I stopped 3 years ago to let my body rest and after I got my next shot 6 months later everything hit me with a vengeance. I just recently turned 40 and I thought I was going into early menopause. I am off the shot 7 weeks and suffered a severe withdrawal last week I was stuck laying in bed for 6 days with extreme fatigue, severe depression, very scary I wanted to end it all, body aches, night sweats, slept for 14 hours at a time, body acne, smelly discharge, no appetite and extreme anxiety. I feel a little better but still scared it might all return I do not have the strength to fight it. I am taking macafem and it has helped with the symptoms but I do not feel 100% yet and still feel very weak. This shot is a poison and evil because it has a way of masking itself and leads you to believe its not the cause. Please stop using this and find another b/c or do not ever consider if you are looking for a b/c. It will all catch up to you eventually, not having a period is toxic to your body and can destroy your well being. Please say a prayer for me I really need some!!! Thanks for reading and God Bless. F 40 18 years
250 mg IM 1X AN
7/9/2011
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 4  Prevent pregnancy I have noticed myself being a lot more tired lately, as well as more emotional. I have also had some spotting, which comes and goes but is never very bad. As well as this I do have occasional headaches although I'm not sure that is completely related. I admit I didnt read too much about the shot before having it, but fourtuneatly I havent found the side-effects nearly as bad as some people have said. I have always suffered from moodswings and being emotional but at some points I was suprised at myself and how much I would cry at nothing. I also have been very tired lately and found it very difficult getting up in the mornings, even when its not even that early. However, I dont think the side-effects are majorly bad and I think I would recommend its use but definitely be prepared :) F 19 5 months
1X O
7/7/2011
 3  Birth Control & Period No weight gain, No mood swings, nothing except weird periods. Started it at the age of 15 and I am now 17. I had my period for 2 months straight when I first got on the shot. After that I only had it very lightly at the end of the 3 months. I have now been on it for 2 years and just recently started getting a heavy period for about 2 weeks now. I am still on the shot but if i continue to have this weird heavy menstruation I will need to get off of it. It will go away for like a day and then come back pretty heavy and it isn't normal period blood. It is thinner and really red like when you get a paper cut...! Up until now it has been good for me. I also got my period during sporting events but that is probably because the shot makes your uterine wall thinner and weaker.... F 17 2 years
1X day
7/6/2011
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 2  contraceptive I have gained alot of weight and did not realise why as i have been eating a healthy diet and exercising. I have been getting bad spots and greasy skin, i feel tired all the time and my body aches, my ankles have swollen which i have never had before. My periods stopped and then started again. My breasts have got huge!! and they feel sore and swollen. I have terrible mood swings and feel sad and depressed alot of the time. I am thinking about not having the next jab seriously i cant go on gaining this weight F 40 18 months
1X AN
7/4/2011
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 1  My mum wanted me to Bad headaches. Feeling sick not long after I have headache. Got sick a few times. Major weight gain. Tired all the time. Light, but long lasting periods. Acne problems. Depressive moments. Sharp pains in my pelvic area every now and then that last up to 5 minutes. Slight hair loss. Muscle aches in arms. Bathroom problems. Losing motivation in what I use to be interested in. When I first got the injection a year , as my mum wanted me to since I started to go out with a older guy, who I am now engaged to, I got real sick about an hour after the shot. I have a server headache, and felt like I was going to be sick. I felt like that for the rest of the day, and I was soo tired. I eventually had a period every few months, but mostly after a big event happened that stressed me out somehow. The period was light, but lasted for about 2-3 weeks, when it normally lasts 5 days. I use to weigh 63kg, but now weigh 80kg (that is way to much) I now have acne problems. I am tired all the time, I use to be able to stay awake till 4am easy, but now I am struggling to make 10pm. I am constantly falling asleep, which is not good as I am at Uni, and can't afford to fall asleep in lectures, which I have done too many times now. I get a sharp pain that shoots through my pelvis area every now and then, which is uncomfortable, they sometimes last up to 5 minutes, and happen through out the day. I get upset more easy. Now since my last shot a month ago, I have been having a headache every week on Saturday, which generally is followed by the feeling of being sick, which has happened. When this headache occurs, it lasts all day. No pain killer can prevent the headache. Also when I have a headache, all food is not appetizing, no matter how hungry I am, I try to force myself to eat, but my body is almost rejecting it, so I go a whole day without eating, unless I ate before F 17 1 years
unsure 1X AN
7/2/2011
 3  pregnancy prevention Mood swings, depression, anxiety, fears over everything, acne, swelling of the hands and feet and mild fatigue. Negative effects: I'm a completely different person on this medicine. I'm usually very capable of controlling my emtions, but with this shot I'm a mess. I cry all the time over nothing whether its positive or negative. I'm also a very logical person but seem to have developed uncontrollable fears accompanied by anxiety attacks. I've also never really had acne, even as a teen, but seem to have developed it afer taking the shot. Nothing horrible, but I do have acne all over now. I also have swelling in my hands and feet at least a few times a month. Nothing terribly painful, but it does hurt mildly and becomes bothersome. Positive Effects: To speak to the positive, I'm not pregnant, so it did what it says it does. I also had no weight gain, or headaches. Would I reccomend it? Probably not. Its really nice to just have one shot and forget about it, but the effects aren't worth it. Especially with the bone density risks. Had I known of this before taking it, I wouldn't have. F 26 4 months
4X O
6/28/2011
 1  Prevent pregnancy I had horrible mood swings, thoughts of suicide, terrible acne, wt gain which added to my depression. It caused me to quit my job due to constant fatigue. Can't wait for this nightmare to be over. F 21 3 months
1X O
6/15/2011
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 1  Prevent pregnancy I had horrible mood swings, thoughts of suicide, terrible acne, wt gain which added to my depression. It caused me to quit my job due to constant fatigue. Can't wait for this nightmare to be over. F 21 3 months
1X O
6/15/2011
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 2  to stop pregnancy weight gain. aches and pains through out my body. cramps and tenderness and a dull aching sensation round my pubic bone region. mood swings. VERY irregular bleeding ive only had 2 depo jabs but so far am not liking what my body is experiencing and doubt very much whether i'll be going for a 3rd jab. after the 1st one i wasnt too bad - pretty good infact - just some irregular bleeding and tenderness around my 'bits' towards the end of the 3 months. but its now - after the 2nd jab, i'm coming up to the end of the 3 months and feel worse than ever!! aches and pains from my ribs downwards, a dull aching sensation around my pubic bone area (which is constant and doing my head in!) feeling tired all the time, mood swings and very irregular bleeding. i'd advise anyone thinking of having this to think long and hard about it - i dont think the doctors make the side effects clear enough to people and while it may suit most people its obviously having some nasty effects on others which you are then stuck with for 3 months until its worked out of your system. F 29 2 times
1X O
6/12/2011
Email
 1  Birth controll mood swings and lots of weight gain, and chest and lung pains when exercising I started taking the shot in March and started gaining weight in late May. I gained 10 to 20 pounds. And I try to exercise but then I get chest and lung pains and it hurts to breathe I will be off it in August though. I want to try a non hormonal birth control pill. F 19
1X M
6/12/2011
 4  Birth control just a little sleepy I have been readind some of the comments and wonder if most of the women on here were completely healthy or have any family illnesses that the shot could trigger. Because I am very healthy only allergy I have is penicllin. It is rare for me to get side affects from anything I take so it could just be your family history or your health. If I were to get mood swings I would not let it distroy my marriage or loose my boyfriend because you have to learn to control your anger we are adults here you dont have to say what pops into your head if you know its going to hurt the other person. Weight gain I believe there is no way you are stuck being 20 or 45 pounds if you dieting and excercising. It makes no sense you are either not keeping up with excercising or overeating. The only thing I am worried about is the bone lost so I wont be on the shot for more than 3 years. F 22 3 days
1X AN
6/11/2011
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 5  To Start My Period, "Possible PCOS" No Side Effects Really. The 9th day I felt like my Feminine Organs Were Trying to Work Again. I felt the Same way 1 day after I stopped taking pill and the 2nd and 3rd. I was all worried I wasnt going to start. This is my First time taking the Provera Pill, so I did not know what to really expect. I didnt have any side effects like some did. I really thought I would have. This is the 3rd day after I stopped taking the pill and I have started. I thought I was going to start Possibly 2 days ago, so I wore a liner just incase;) that day and yesturday. All I can say is its been 5 months since I had my Period last and Man, I feel like a woman! F 21 10 days
10mg 1X day
6/9/2011
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