DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  birth control diarrhea, tingly hands and feet, no sex drive, did not like to be touched whatsever, heart palpatations, every pregnancy symptom (all negative), no period..period returned right away then nothing, ovarian pain, extremely swollen and super painful breasts(more severe than pregnancy breats), increased appetite, HUGE WEIGHT GAIN (kept on my gestational diabetic diet 150 carbs per day gained 30 lbs in 3 months... hard to keep weight on when on this diet during pregnancy but while on this shot decreased carb diet from 200 per day to 150 STARVING ALL THE TIME yet weight kept packing on) started depo march '09till august '09. had first post depo period oct16-31 '09. the extremely light one nov 18-21 '09. now feel pregnant but 3 negative tests. more than 55 days late. i spoke with my doctor and she wants me to do i pERIOD DIARY to track my cycles for 3 months. um.... how can i do that when im not gettin......g my period and every symptom of pregnancy??? she didnt even offer or tell me to come in for a blood test to confirm whetther i am or not. they never tested for pregnancy when i first recieved the shot or during my second and final shot. im calling in for a new doctor. this is my body and if somethings really wrong waiting can actually hurt me more.... thanks for listening. i still think im crazy and this is all in my head but at least i know that there are many many other women in the same boat as me going crazy and waiting. F 27 6 months
1/10/2010
 1  to help ease my worries of periods many different mood swings,suicide attemts/thoughts,weight gain,depression,body acks,and now the hair loss This is now my 3rd time around tring and experiancing with this med after having my now 3rd child. it has been almost 5yrs since i had the last dose with my 2nd child before i almost ended up in the loony ben for crzy pple. almost had my kids taken away at the same time this drug was not only taking my self worth and importance but it had completely distroded everything i had. if i had to sum it up in a small sentence it was like being additied to a street drug like crack or methodone or something like that. i had no care in the world for anything that met dear to me including my own children. but at the same time going threw HELL was like waking up in a haze memomory or like being trapped inside your own body fighting ur demons and thats exactly how i felt. when i had my first breaking point which ended me up in the hospital tring to OD on prescription muscle relaxants and slitting my rist i knew enough was enough so i thought. i also have been one of those pple who have had the severe migrain headachs and back pain repeated mood swings mostly the angry ones along with many sucidly thoughts/attemts. i had no clue on what those things ment so i confided in a friend who did researching on the computer for me and told me to get off as soon as possible but since i didnt choose to take her advice iv lost a great friend to me. i lost all my friends and family and including my husband of a almost 2-5yr relationship i say that because he stuck around as long enough to what he could F 26 1 months
1/10/2010
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 1  Birth Control Massive weight gain, increase in appetite,no periods. I gained 21 pounds in weight and it was all in the wrong places!! I felt bloated and was hungry all the time. I watched my weight creep up every time I had a check up and the Depo. I came off the Depo in March. Since September 09 I have lost 21 pounds, my periods returned and I am my usual slim self, I have joined a slimming club where you have green days and red days!! and I have increased my CV work at the Gym to increase my metabolic rate, I believe that all these three factors have helped me to return to a normal weight. I have been to hell and back with the effects of this injection as I became very depressed due to gaining weight and I thought that my partner would leave me at some stage!! My friend at work told me I would lose the weight after six months and that support kept me going. I was never told how much weight I would gain and I was never given proper guidance or support when I was given this injection. I would advise any woman not to have this injection as it causes no end of problems and these are irreversible until months later. Think twice before you consider this form of contraception. F 41 9 months
1/8/2010
 1  Birth control Diarrhea, headaches, fatigue, bleeding all the time, and mood swings. I would not recommend this shot to anyone, I've always been a high energy person. I worked long hours before i got this shot for a couple of years and it never phased me. But, now that I've gotten the shot it seems like i can sleep for fifteenth hours and still be tired. I'm always upset or angry about something now, and before i was usually happy or content the majority of the time. I'm still on the first shot and have been bleeding heavily for about two weeks now. Also, i have been getting constant headaches every day. Finally, i get to the appetite change, I don't eat more, i eat less. I can't even stand to look at food half the time, sometimes even the smell of my favorite foods make me sick. I would NEVER recommend this shot. F 21 1 years
1/8/2010
 1  contraception extreme tiredness/lack of motivation, irritibility, suicidal thoughts, feelings of low self worth,constant bleeding, mood swings, not knowing who i am or what i want, anxiety and panic attacks which havnt been present for years, change in bowel habit,lost 1/2 a stone in a week...and then gained almost a stone the next week and half, heartburn, indigestion,bloating, heart palpitations...and on and on in the 1st 2 weeks i was extremely moody and felt suicidal up to twice a day...didnt know wether i wanted to be with my oartner..and there was no apparent reason for this, sex drive was extremely low in the 1st month, diarhea in the 1st month, bleeding started just before the 2nd injection was due, i thought it was slightly longer than usual...but didnt think it would continue with the 2nd injection...about 30 days and counting. with the 2nd injection came increased anxiety, irritibility and a huge panic attack along with smaller 1s. Since the start of the injection i have been sleeping a hell of alot , have had bloating, indigestion and heartburn...none of which i have ever had before. The suicidal feelings made me leave my mediaction in the hands of my partner..scared to have it with me. Scared of socialising...and before this injection i had been better for 2 or more years. The acid,constipation etc and weight gain made me feel so pregnant...i was paranoid non stop...i wouldnt recommend this to anyone....research and dont make the mistake i did..i feel like im falling apart... F 20 4 months
1/4/2010
 3  birth control weight loss, no period, no pms symptoms, loss of libido I took depo on and off for about 6 years, and I was one of the few that lost weight on it, about 25 pounds, for that reason I loved it. The other side effects I could do without. I went off the shot about 12 months ago, my cycle still isn't normal, one month I will get my period like 2 times, other months I don't get one at all, or it's only like 1 day. I am 28 and went off the shot so that I could start a family soon, I guess it was a little more long term than I thought..keep that in mind if you are deciding to use this. I don't have a normal cycle yet but I do get all the symptoms associate with it like moodiness, pretty bad lower back pain, etc. If you are on it or are planning to take it remember there are other options that are less long term and that do not mess with your body's natural cycle. F 28 6 years
1/3/2010
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 1  birth control It seems that I am displaying a lot of the symptoms all ready posted on this site. I feel as if this drug has turned me physcotic, i am aggressive, abusive, embarrassing,in pain and often have sucidal thoughts- although I am stronger than that! My husband dislikes me i am sure and since been on the depo i have gained 3 stones ( I am so sad witrh myself and I feel there is no one to help me!) Severe weight gain,physcosis, aggressive, abusive, embarrassing, pain and sucidal thoughts. NEVER EVER TAKE THIS POISON & I AM A QUALIFIED PHARMACEUTICAL SCIENTIST, WITH FIRST HAND EXPERIENCE F 36 3 years
1/3/2010
 1  Not sure Why Head aches, server back pain, server cramping and stomach pain, nausea, bleeding....DO NOT GO ON THE DEPO....i was on the pill at one point and never got any side effects...on this i got many! What sucks more is i will probably be in pain for the hole 3 months..its only been 2 weeks and its already effecting my love life and work life. I will never get this shot again and dont reccomend it to anyone. I am also very upset that my dr did not discuss w/me anything about the shot. If he had i would have told him rigth away to put me on the pill. i would have been able to control how long i took it then so instead of 3 long months plus possible more if it dont leave my system right away. I could have taken the pill just until my leavels were back to normal...DO NOT GET THIS SHOT!!! I had gotten pregnant last april and made it till 22 weeks(which was sep.) and at that time i had had a still born. I never actually got another menstrual cycle and in late november i found out i was pregnant again. Shortly after i was told that again it would be another miscarrage. I had a dnc done and while recovering my fiance advised the dr i was against going on the shot but right when i got back from recovery they gave it to me anyways. I guess they thought it would help lower my hormone leavel which i guess was important at the time. but im sure other froms of birthcontrol would have been just as effective and could have been easaly stopped after my levels have gone completly down, but now i have to waite even longer. After that not even a week later i exsperianced alot of pain especially in my back and stomach. i went to urgent care and they werent sure what the pain was from so just put me on pain medication and sent me on my way. A few days later i was back again, and again was given muscle relaxers(which did not take sence could not function on them) and another pain medication which did not work. I now know from looking up the shot that my problems are from it. I am very upset that dr put me on this form of birthcontrol sence he knew i would want to try again right away to get pregnant. but now will have to waite awhile plus have to deal w/the pain which is hard when i am a waitress and on my feet 5 days a week. F 24 2 weeks
1/3/2010
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 1  birth control side effects; cramps in the leg, abdominal pain,weight gain, eating more often,never ending cycle 2 doses of the shot and still have a cycle F 17 5 months
1/3/2010
 3  Contraceptive Progressive weight loss. Loss of libido, dryness contributing to loss of libido. Initially heavy bleeding for first 3 weeks, then no period or on rare occasion spotting. I used to have bad PMS, so having no period helped control my mood swings. My problem is not with being on Depo, but when I decided to come off it. I'm one of the unusual tiny percentage that actually lost weight on depo. I was on it for 2 years, and by the end of the 2 years I lost about 8 or 9 kilograms! I did not change my eating habits or appetite, nor did I increase exercise. I was taking no other medication so can attribute the weight loss to the depo. I thought this drug was a god-send with regard to having no periods and much better moods. However, I when I decided to come off the injection I suffered some uncomfortable symptoms. After the first missed injection (3 months after the last one) and progressively over the past 12 months since my last jab I have gained back weight no matter how hard I try to keep it off. I still have not had a period, however do have pms-like symptoms every month including bloating, tender breasts, headaches, back ache and insomnia - however no period follows all these symptoms! I understand it takes up to 18 months and sometimes 24 months for fertility to return. It has been just over a year and still no period! I'm almost tempted just to go back on depo to lose weight again.. but really want fertility to return so I can start a family soon! I guess my overall comment is that as a contraceptive it is extremely effective. A bit too long term though! Hard to gauge how one's body will react to getting rid of the chemical over time and how long it'll take for fertility to return. F 27 2 years
12/30/2009
 1  birth control Back pain, headaches, Moodiness, suicidal thoughts, made me crazy. don't get on this birth control. I've tried everything and this by far is the worst. I'm finally on a low estrogen pill. I was a happy person up until getting this shot. Gaining 20 lbs is just one of the motivations for getting off depo. In addition, I became moody and mean often(especially with my husband). Also lost my sex drive COMPLETELY. Hope these side effects will go away soon as I've only been off depo for a few weeks. I kept up with the shots for a year hoping side effects would dissipate but they only got worse. F 35 365 days
12/29/2009
 4  Birth control very long periods, periods every 6 months after the first year, hair loss, weight gain, PMS symtoms without having an actual period, calcium loss resulting in enamal loss resulting in cavities. I started on Depe when I was 17. The first year I would bleed and spot for 45 days then no period for 45 days. It was horrible. After a year, I would only have my period every 6 months or when I had high stress. My hair thinned out. I gained 25 pounds in 5 years. I would have all the symptons of PMS (moodiness, breast tenderness, appetite change, fatigue)every month but not actually have a period. I also have had 8 cavities in the last 5 years. I had never had a cavity in my life until 6 months after being on depo. I actually have mineral deposits on my teeth which strengthens them. I drink milk take supplements and I brush and floss my teeth two times a day but still I get cavaties. Now I am getting off of Depo. It's been 6 months. At 3 months I spotted, but now I have a period with heavy bleeding last more then 4 days. I used to bleed heavily before I was on Depo but it only lasted a day or so. I'm not sure if that is suppose to be a side effect. F 22 5 years
12/26/2009
 5  switched after takin pill for 4yrs Decreased sex drive I switched to the depo shot after taking the pill for 4yrs, I didn't like having to remember to take a pill everyday and I liked the idea of not having a period. I've been on it for 5 and a half years, I don't plan on getting off it anytime soon. I haven't had my period at all the whole time I've been on it, no spotting either. I love it. The doctor told me that the people who expierence lots of bleeding and awful side effects that its because its not working the way it was designed to, it just doesn't work right for some people, everybodys different and its working out great for me! Only bad thing for me is the decreased sex drive but its dealable, I have a busy life and don't have a lot of free time anyways and I like to get a full nights worth of sleep. The only other bad thing is the bone loss but I take calcium supplements so hopefully its helping! F 23 5 years
12/23/2009
 4   I have been on depo for the last 8 years. About 3 years ago I took a break because of the bone density but the test came back normal. Just recently I came off of depo because I was married and my husband wants to start a family. I have a 9 year old son and we are wanting one more child. I got on depo because I had the most awful cycles and I cramped so bad I had to miss days of work. I really enjoyed the no menstruals. My Dr. did say that after coming off that it could take up to a year to become pregnant, which is around the time we are plannig on conceiving. My Dr. told me the first time I got off of Depo that I needed a form of BC to regulate my cycles again, so I got on the patch. I had regular, lighter cycles without issues so I couldn't complain. I just came off 2 months ago. I haven't had my period yet bc I haven't started my new bc patch so I will see how that goes when I begin my bc on Sunday. The only issues that I have had when off is the swollen, sore, itchy breast. It really is a pain and it hurts to touch especially when taken off my bra. I think this is one of the reasons I stayed on for so long because when I missed shots it would happen. I also recently have gained about 30lbs even when killing myself in the gym it will not come off, so I am looking forward to getting back in shape. Would I take depo again after conceiving probably. I really did like it, but I know I can't stay on it forever. IUD is really not an option for me, I hear the side effects are sometimes worse than the product. F 27 8 years
12/23/2009
 1  4 kids is enough gained 29 pounds with the last shot, fatique, insomnia,sore back, feeling depressed once and a while, no energy and just feel like hang out at home all the time...and OMG I have been bleeding continually since my last shot in Aug (its now Dec 22) prior to that I would always start bleeding again about 2 weeks after getting the shot. My Dr is aware I have been bleeding for so long yet doesn't think anything of it, nor does she express any regret on not telling me the "possible" side effects...clearly she has no idea what its like to wear a pad for 5 straight months...yup...just a tad choked and hope this will stop someday....I wonder if it will and when...mmmm My dr. suggested depo because of my age and I smoke and the BC isnt good for smokers or ppl my age. I was married 15 yrs to a "fixed" husband after our kids and am in a new relationship now for the past year and a half and this is why I went on it...thank God he still loves me. I have not taken a shot since Aug yet still have the poundage...only benefit is I now have boobs..haha...I have never weighed this much and it REALLY bothers me and need it to be gone...I have a closet full of clothes that dont fit...I wish I did research b4 taking this. I never knew about ANY side effects...would I suggest this shot...HELL NO!!! I would rather have my guy use a raincoat. F 40 4 times
12/22/2009
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 1  4 kids is enough gained 29 pounds with the last shot, fatique, insomnia,sore back, feeling depressed once and a while, no energy and just feel like hang out at home all the time...and OMG I have been bleeding continually since my last shot in Aug (its now Dec 22) prior to that I would always start bleeding again about 2 weeks after getting the shot. My Dr is aware I have been bleeding for so long yet doesn't think anything of it, nor does she express any regret on not telling me the "possible" side effects...clearly she has no idea what its like to wear a pad for 5 straight months...yup...just a tad choked and hope this will stop someday....I wonder if it will and when...mmmm My dr. suggested depo because of my age and I smoke and the BC isnt good for smokers or ppl my age. I was married 15 yrs to a "fixed" husband after our kids and am in a new relationship now for the past year and a half and this is why I went on it...thank God he still loves me. I have not taken a shot since Aug yet still have the poundage...only benefit is I now have boobs..haha...I have never weighed this much and it REALLY bothers me and need it to be gone...I have a closet full of clothes that dont fit...I wish I did research b4 taking this. I never knew about ANY side effects...would I suggest this shot...HELL NO!!! I would rather have my guy use a raincoat. F 40 4 times
12/22/2009
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 1  Birthcontrol Being a active mother in my childrens lives i condoan birthcontral in the early teen years to prevent any mishaps. Depo sounded like the perfect form of birth control for a teen, no periods and never forgetting to take the pill. After her first injection she was a demond child, angry, depressed and totally defient, her home and social life suffered! We decided not to get the second injection and i now have my outgoing, loving, fun and full of life child back!!! F 15 3 months
12/21/2009
 1  Hard to remember the pill. Almost constant bleeding...no wonder it is rated so highly effective - who is having sex with all the bleeding!? I do not plan to get the 3rd shot and would not recommend this form of birth control to anyone. F 48 2 times
12/18/2009
 5  Birth control/Control heavy painful less heavy periods, less painful periods Been on depo 6 years, awesome. I am heathly, bone density normal, no weight gain, happier, no babies, light periods. Depo doesn't cause strokes or DVT, pulmonary embolism or myocardial infractions geniuses!!! it decreases endometrial cancer by 80%, decreases risk of iron deficiency anemia, pelvic inflammatory disease (PID), ectopic pregnancy, and uterine fibroids, endometriosis and incidence of primary dysmenorrhea, ovulation pain, and functional ovarian cystsaverage return to fertility is 9 to 10 months after the last injection. By 18 months after the last injection, fertility is the same as that in former users of other contraceptive methods. Maybe you shouldn't consume sugar or breath traffic air either F 22 6 years
12/17/2009
 1  We didnt want a baby at the time Weight gain, head aches, anxiety. I took one shot in june of 09, never took my second one in september of 09 because of all the issues. I never had a period while on tat first dose and now, here it is dec. 09 and still no period, no spotting, no cramps. We are trying to have a baby and cant I guess since I am not having a period. I have no symptoms of a period at all, and its been 6 mths since my one and only shot. I still have not lost the weight or the anxiety. I dont know what to do as we are desperately trying for a new baby but Im sure I cant get pregnant without a period right? F 29 1 months
12/14/2009
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