DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2474 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  For use by females of reproductive potential to prevent pregnancy. Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is also used with or after other treatments (such as radiation, surgery).   (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  FDA Adverse Event Summary

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth Control EXTREME wait gain, headaches, EXTREME moodiness, anxiety, joint and muscle pain, complete loss of period I started taking the Depo shot 6 weeks after my daughter was born, by my second shot I had gained 60 lbs (after losing all of it and being down to my pre-pregnancy weight), I had completely lost my appetite and was barely eating anything (small salads and stuff to keep food in my system), but gaining faster than ever before. My period stopped all together which I didn't mind, but I was still getting bad cramping. I got bad headaches and my joints and muscles hurt all the time, I had NO patience for my baby and my friends and family said I was very moody and on edge all the time. I stopped getting the depo shot before my 3rd shot, and it has been 2 years and I have only had my period once since then, I still get bad cramps and joint pain, I haven't been able to lose the weight even after following a strict diet my doctor put me on, My Doctor said there are steroids in the shot that I didn't know about before I started taking it, and that's why I had such weight gain. This form of birth F 23 6 months
9/12/2008
 1  birth control Really bad bleeding for 2 1/2 weeks, really bad lower abdominal pain, HUGE mood swings, angry ALL the time, the smallest thing sets me off, no sex drive AT ALL most of the time I don't even like my boyfriend to touch me, always seem to be bitchy when I try not to be its like i cant control it or do anything about it. It was a few weeks after i got the shot that I began to slowly change, and I feel like I dont even know myself anymore. I'm just so moody and bitchy all the time and that's not like me at all! I HATE Depo!!! I will never ever take it again!! I've had nothing but problems ever since I started taking it!!! Take my advice and do not take it. My sister warned me before I took it not to, but I didnt listen to because Im really bad about taking a pill everyday. Now, every day she says "I told you so!!!" F 22 3 months
9/10/2008
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 4  No more children for me! I first tried the Depo shot when I was 17 and went off it due to a constant period that last for 7 months. This time around was different...in the beginning I had the hot flashes, acne that wouldn't go away, nervousness, and headaches. I also started spotting the same day I got the shot..spotted for about 8 days. I had horrible mood swings and would cry for no reason at all. My poor boyfriend was getting frustrated with me. I told everyone I wasn't going to get another shot..it was horrible! The worst side effects lasted for about 3 to 5 weeks and I have had basically no side effects since then. I lost 11 lbs in the first three months. I have no period..no spotting either. I still have the mood swings, but I just try to laugh them off. I still cry a lot more than I am used to, but again I try to just deal with it. It's much easier on the Depo..no pills to remember everyday! I wouldn't trade it for the world! I just got my latest shot and there will be more to come! If I got through the side effects, you can too! You just have to want to get through it. F 23 3 months
9/5/2008
 1  birth control i THOUGHT that the only side effect was no period, which was awesome and why i stayed on it so long. now i look at what everyone has said and i realize that there are too many coincidences. the effects that i have in common with others are: unstable mood swings, feelings of depression, lack of sex drive, dryness, painful sex, horrible night swears. ALSO now have been diagnosed w/ OSTEOPENIA I feel sick to my stomach when I look at what everyone is saying and actually thinking that I could get away with not having a period for almost 10 years and not having other side effects. I have been diagnosed with osteopenia (low bone mass density, now at risk for osteoporosis) and ONLY found out b/c my Best friend was diagnosed and told me to get a test-not even my DOCTOR told me anything. i have been in denial and now i know that i not only HAVE to get off it to try to reverse the osteopenia, but hopefully I won't feel unhappy, unstable, and will get my sex drive back. PLEASE be careful of the side effects and don't get caught up in the thrill of no periods like i did. only take short term and/or if you are going to be sure to take the calcium supplements to make up for the calcium the depo leeches from you. this didn't work for me b/c the whole reason i took the shot was b/c i couldn't remember to take a little pill. . . F 27 10 years
9/2/2008
 1  birth control Dipression, mood swings, gained tons of weight, no sex drive at all, headaches, bones hurt, bachache.... you name it I was on the shot for 9months, cried for no reason, I was so depressed... my husband had enough of me. Thank God for my sister, I kept denying that depo was the problem there, and she opened my eys, I am off it for 3 months now. Different person, love to love my husband, love being around people and hate my waist. Im normaly happy now. I still have bad hadaches every day, I was told that it will get better with time.Stay away from this drug, I would rather have a child again F 25 9 months
8/28/2008
 5  birth control & control bleeding I guess I am very fortunate. I love the depo shot!! I have been on depo for 15 years, I have never had a single problem with it!! I did get off it briefly after having a tubal, but my irregular periods were just like they were when I was young so now once again I am back on it. I will take it forever if the Dr lets me!! F 35 15 years
8/26/2008
 4  birth-control and no cramps only that ive gained 5-10lbs...in the beginning was rough but ive been on it for 7yrs want to get off of it for a bit but since i havent had my shot i just want to eat...but thats it F 30 7 years
8/26/2008
 1  I GOT PREGNANT WITH THE DEPO SHOT I'VE HAD HEADACHES, I WAS EATING ALL THE TIME AND AS A RESULT OF ME EATING ALL OF THE TIME I GAINED ABOUT 3 POUNDS SINCE I'VE BEEN ON. I'VE ONLY BEEN ON FOR ABOUT TWO MONTHS AND I HAVENT EVEN GOT TO THE SECOND SHOT YET. I DONT KNOW IF YOUR EYES ARE SUPPOSED TO BE SWOLLEN BUT MINES ARE, THEY'RE VERY PUFFFY AND THAT'S UNUSUAL. I'VE GOTTEN A SORE THROAT I'VE BEEN FEELING NAUSEA AND IT SORT OF FEEL S LIKE I HAVE A FEVER OR EVEN THE FLU IF THESE ARE NOT SIDE EFFECTS MAYBE I AM JUST HAVING AN ALLERGIC REACTION. WITH ALL OF THAT SAID THE DEPO SHOT IS HORRIBLE. F 15 2 months
8/19/2008
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 3  birth control wanted no pills hair loss,weight gain 5-15 per shot, moodswings, no sex drive, headaches, dizziness, painful cramps in lower abdomin. Good for not getting pregnant but side affects not worth using this drug.I have gained lots of weight (30lb)and when i lose some the next shot brings back all i lost and more. Do not use this drug, it caused osteoproses. Did you know they use this drug to lower the libido of sex offenders? IT is illegal in many countries and it should be here too. I got my last shot in july and i am never going back, i rather have another baby!! F 20 13 months
8/18/2008
 1  Extremely painful cramps lasted wks 40 day period that only stopped when I started birth control pills; extremely painful cramps. Usually I have cramps for two weeks out of the month. On Depo Provera, they were longer and more painful. Tired, nauseated, sore breasts, constant bleeding that wouldn't stop. One shot was enough. Do your research before you decide to take the shot. I only researched the Depo Provera site and believed it when my doctor told me after the shot, "You won't have a period again." Yeah, right. Worst decision I ever made. Made life worse instead of better. F 34 3 months
8/18/2008
 5  Birth Control Very slight weight gain I am 47 and decided on depo provera last year since I previously had breast cancer and most forms of birth control not an option for me. Depo has no estrogen so I decided to try it on my physician's recommendation. Had continuous brown spotting for the first 3 months on it which was extremely annoying, but after that, no side effects to speak of. I originally weighed 113 lbs when I started the depo, and after a year and a half weigh 117 lbs so not really sure that my slight weight gain is a direct result of the shot. I really like the convenience of a shot every 3 months and have none of the numerous side effects most posters here have written about. I would highly recommend this as an effective, easy form of birth control. F 48 1.5 years
8/14/2008
 1  Birth Control No periods,Depression,Dryness,Crying for no reason,loss of libito, and this is my wife, Girls, I could go on for hours about this awful stuff, dont use it , Try something else, My wife has been off this for two years now, its GREAT, totally diffent person, The Depo should been banned. M 43 10 days
8/11/2008
 1  prvent pregnancy Acne (I never had acne before), fatigue, EXTREME joint pain, NO sex drive, painful sex (the two times I actually did have sex) my three months ended two days ago and NEVER AGAIN will I get another shot. My bones ache all day everyday and I am 22. What is the point of a BC method if you don't want to have sex anymore due to pain?? WHAT A JOKE. I Do not recommend this drug to anyone. F 22 3 months
8/11/2008
 1  to control bleeding I have to buy new clothes every couple of weeks because my weight gain is so rapid; about 2-4 lbs every two weeks. I've gained about 20 pounds in total. By the end of the day, I'm so bloated that I can't get even baggy clothes off. I suddenly have acne all over my face and I've always had excellent skin. I have no interest in sex and it has severely worsened my depression. Lastly, in the first eight weeks after my first shot, I was fine for two and bled for six weeks: I spent $200 on tampons in that time period. I had surgery for endometriosis and went on the shot after the surgery failed to control my bleeding. I would rather bleed and have pain than go through this-the weight gain is disgusting. Most people gain about 10 lbs in the first year; I gained that in about a month. F 23 4 months
8/11/2008
 2  birth control pills affected me bad Horrible hip and back pain, my hands and feet hurt all the time,sometimes i couldnt even make a fist.I walk like im 80 instead of 29.My legs ache, it feels kind of like growing pains from when i was a teenager. i could sleep 10 hours and wake up exhausted. I gained 23 pounds in 6 months even though none of my eating habits changed. I have vaginal dryness and NO sex drive. The only good thing about depo is i have only had one period and it was right after my first shot. It may work for some, but im not getting the shot again. F 29 5 months
8/7/2008
 2  no periods boils, headaches, vision problems,leg cramps, stomach cramps, irritable bowel, tired, no desire for sex I was on the depo shot for 6 years and had my last shot (ever!) in June 08. The first 4 & 1/2 years were fairly problem free. I gained weight (50 lbs) but can't say it's due to the shot, as I like to eat and was already heavy. I added a lot of girth around the middle and look more pregnant than I did when I actually was pregnant. I've weighed this much in the past and my body shape has been curvy rather than middle heavy. In the last year and a half I began to get boils on my butt and upper thighs. At first it was only once in awhile but that led to having several at all times and horrible scars. I also began to have stomach problems, cramping and frequent bowel movements. In the last six months headaches and vision issues have come into play. I continued to deny that the depo was the cause of the things going on with my body. Coming to this website really opened my eyes. I'll never get another depo shot and surely hope the side effects don't linger for too long! F 40 6 years
8/7/2008
 1  pregnancy prevention 7 weeks of non-stop spotting (and still going), weight gain, mood swings, loss of sex drive I have not stopped spotting since the day of the injection. Beacuse of this, or possibly as another sdie effect I was not warned about, I have lost all interest in sex. I have also gained about 5 lbs in 2 months with no change in my diet. I cry all the time and my boyfriend is understandably getting frustrated. I went on this to stop my periods and have a safer more spontaneous sex life, but instead I've been bleeding for almost two months and am not having any sex. Do not take this medication! Nothing is worth the havoc it wreaks on your body. F 23 7 weeks
8/7/2008
 2  not become pregnant nausea,headaches,loss in sex drive,major mood swings, gained weight,being unhappy for no reason, depressed.hot flashes, and being a time bomb. at first it seems all cool then its like your experiencing so many symptoms.who would wanna feel depressed like half the time.not recommended if your in a relationship or have any social gatherings. its just not worth it. F 20 2 years
8/4/2008
 4  Hypertension with Combination pills Weight gain (about 10 pounds), frequent headaches, fatigue Irregular "periods" - no real period for duration, but had a continuous month of spotting It's hard to find options if you can't take BC with Estrogen, so I thought Depo was the answer. Most of these women are VERY dissatisfied with the results, but it hasn't been all that bad for me. All of the side effects mentioned are listed and well known... I'm mainly giving it up as a result of the headaches, but the weight gain might be resolved as well. Everyone's experience is different. It's VERY convenient if your main concern is pregnancy. F 20 1 years
8/1/2008
 3   I started using the injection 3 years ago and was ok with it, lucky for me I didnt have any side effects but then when I red other comments things started to come to mind which I was experiencing and never thought much of it. I found that sex was painful and I had alot of pains in my arms and legs. I am coming to the end of the 3 months and I cant say that its not for everyone because you dont know unless you try it out urself but I have heard alot of bad comments than good but I will not be continuing the use due to trying for a baby in a few months which I hope the depo has not affected my chances. Alot of women like to take the drug because some women dont get their period for 3 months ( like myself which I loved) but think in the long run, you dont need to take a drug if you dont need it. F 24 3 years
8/1/2008

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