DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2474 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  For use by females of reproductive potential to prevent pregnancy. Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is also used with or after other treatments (such as radiation, surgery).   (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  FDA Adverse Event Summary

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  to stop my periods i originally started the depo shot because i found out I had to have a cold knife conization on my uterus and my OB/GYN said i COULD NOT be on my monthly during it. GOSH, I would have rather taken the risk. Here I am, 6 months later, I haven't taken my shot since January and I now have no period (haven't had one since 10/06), I have pain after orgasm (when I actually want to have sex, which is never), my fiancee doesn't understand why he has to beg me to be intimate with him. Emotionally I want to but I'm scared of the pain. I had major depression and mood swings, also. F 25 6 months
7/9/2007
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 5  heavy bleeding possibly weight gain, had been gaining weight before, mood swings when I need to get my shot, none that I get complaints about when I am on it, decreased sex drive This drug may not be the answer for everyone but for me without it my life is not pleasant. Bleeding in my shoes for days each month, terrible to the floor cramping and pain. First shot, period gone, have gone off it, takes months for it to come back but when it does it is just as bad. My mood changes when I am due to have my shot, I can feel it happening, and I will admit that I depend on it to keep me more level. I can feel the PMS when my 12 weeks is up, during the 12 weeks I have no side effects. My mom has some bone density issues and my doctor has suggested that perhaps I go off, not going to happen, it is monthly miracle, and although I understand the effects are different for everyone I say sometimes to have a more normal cycle you need to not have one. F 38 8 years
7/8/2007
 2  Prevent pregnancy I am constantly fatigued. My muscles ache, all over my body. No hair loss. Weight gain (10+ lbs). I have had -3- shots total. I feel like I have been beaten with a stick! I am always tired, insane headaches, depression. Since I have been feeling this constant fatigue and NO motivation to get out and do anything, I decided that it MAY be because of the Depo shot. I do not take any other drugs. I do not have horrible acne, but I have gained wieght. I can feel, about 12 hours after the shot, horrible bone pain. I have to lay down and cry it gets so bad. I am DREADFUL, EVIL and so very mean for about a week after the shot and then I even out. My husband understands, but he also knows that I try to control my bitchiness. I don't want to be mean to him. My biggest complaint is that I am so very tired. I ache, I can't concentrate like I used to (not good for a philosophy major who MAY go to law school), I find that nothing helps. I take Advil PM to sleep, and I want to sleep constantly. I used to do things with friends, and my hubby, but now all I want to do is sit around in my robe and either cry or sleep. I am not getting the next shot, which is due in August. I need to lose weight (I was neve F 37 1 years
7/8/2007
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 1  Birth Control After stopping the shot I have had..... a menstral period 24/7 365 days per year, cramping, bloating, and large blood clots come out. ANY WOMEN THINKING OF TAKING THIS DRUG..... DON'T... IT IS LIKE GOING THROUGH HELL WHEN YOU GET OFF IT. I started taking the shot in oct 2003 and ended them in sept 2004. It took me 3 months to get my period back and now I regret it... I started out having my period 2 weeks on and 2 weeks off... that lasted for about a year... then in Jan. 2006 I got menstral cramps so bad I couldn't even move. Went to the doctors, told her about the 2 weeks on and 2 weeks off and she told me that was normal sometimes a womens body needs to recoup after taking the shot and it can take a few years to get the body back to normal... well that was fine and dandy... she then diagnosed me with hypothyroidism and that is the cause of my excessive bleeding and cramping. Well since that last visit I lost my job and insurance so I can't got to the doctors at this point. but it has now been a year I still have periods 365 days a year 24/7. It's mostly like having a period ALL the time except a few days a month the bleeding will subside to spotting and at that point I have cramping, bloating and large blood cl F 27 1 years
7/3/2007
 5  B/C & No kids Before DP, I was already irregular. After depo, no period like many others. Had migranes which I thought were due to stress. All over body aches which I thought were from lack of exercise&stress. Lower back pains thought to be from epideral. Increased sex drive, increased appetite/sugar cravings. Before depo, 120llbs. Now, 9 years later, 160llbs; thought this was due to having 2 kids and not exercising. People say your body changes every 5 years. Now, I am 30. I have loved Depo up until this year. Now, around the "time of the month", I have been experiencing severe depression and acne I just can not get rid of. I have been on calcium, women's 1 a day, and green tea pills (curbs appetite and sugar cravings, increased energy with natural caffine), blueberry (antioxidant which helps with depression)protein shakes, high-protein diet, exercise, and I have lost 7 lbs in 1 month. I thought losing weight on Depo was impossible! Herbalist recommended SAM-E for depression. I am working on the acne cure still. Depo is not for everyone and after visiting this website, thinking about a bone density test. F 30 9 years
7/2/2007
 1  Birth Control Gained 15 lbs, Swollen Feet and Hands, Hair Loss, Crying Spells, Ab-Normal Moods (up one moment and sad the next), loss of energy. I am a very active person and eat healthy. I box 2 days a week, run at the track 3-4 days a week, work full time, own a all natural bath and body products biz and am a mother of a 9 year old son. So I should not have any reason to gain this much weight in 5 months (cloths do not fit) or to become depressed, I’m also a naturally positive, active and happy person. This shot should not be called Depo Provera it should be Called DEVIL Depo! This has got to be taken off of the market. There are too many uses for it and it was never fully approved by the Government. This is the same drug they give to repetitive convicted sex offenders...this is the same drugs the "experts" say "there are many uses for Depo Provera". I would strongly suggest that women NOT use this as a form of birth control. My doctor warned me, but I am so open minded that I had to learn for myself, and I thinks it’s one of the worst choices I’ve ever made for my health. Never again! F 26 5 months
7/2/2007
 1  BIRTH CONTROL COMPLETE LOSS OF LIBIDO!! weight gain. apprx 5lbs. mood swings. depression, headaches. BOO TO DEPO wow, i recently got off of taking depo. 2 months later, still feeling the effects, but getting better. i can't wait til i feel myself again! i couldn't figure out why i felt this way about sex, and then i started doing some online research and i found out that many women had these same side effects! vtw, it's made my relationship rocky but luckily my boyfriend is understanding...when i talked to my doctor about it, they said they had never heard of these kind of side effects (loss of interest in sex) they did say that women report having a dryer vagina because it lowers estrogen, and they recommended switching to an estrogen bc instead. i can't believe after reading all of these women's comments that no one is doing anything about it. wow. F 22 6 months
6/30/2007
 1  Unbearable cramps. WEIGHT GAIN I don't know of any other side-affects other than weight gain, but that was enough to do it. First of all, the male gynecologist I went to (at age 13, so I elected not to have my mom in the room) said that I had a choice: I could have a period every month, or I could have one never. I was 13. I was dealing with cramps bad enough to keep me bedridden all day and still have to hold my breath to get any relief at all. And he tells me I can have a period never again. What 13-year-old wouldn't choose that? That doctor ended up giving me the Depo shot without my mom knowing, and having mislead me about the side-affects. My mom was furious. And what's worse, he said that the one of the side-affects was, "possible increased appetite." That's COMPLETELY different from the 30 pounds I gained the first summer and the total 65 pounds I gained before I went off of the medication a year later. 65 pounds. I'm the only 17-year-old I know who has worse stretch marks than a woman who' F 17 1 years
6/29/2007
 5  breast pain and tenderness no period, lower sex drive, possible loss of bone density I started depo for birth control while breastfeeding and happily discovered that it relieved me of the nearly constant breast pain that I had had for 3 weeks of every month since my early 20's. They used to hurt whether or not I was on birth control. I seem to be the only person on this site with this situation. I have been very happy with depo, but I am going to stop soon to protect my bones. I do worry that my breasts will hurt again like before. I don't know if my periods will return as I now have hot flashes and have started menopause. Depo seems not to have affected my weight nearly as much as my exercise and diet do--my weight has varied by 12 lbs. up or down in 9 years. F 42 9 years
6/27/2007
 4  birth control bone-joint aches severe fatigue nervousness no weight gain, but I cant loose my pregnancy wieght I have only had one shot so far, and I wasn't informed by my dr at all. But after looking up side effects I realize that the pain that I have been feeling in my bones and joints which worsens after a short walk is due to the shot, also lately I have been experiencing severe fatigue, like 12 to 14 hours of sleep whenever possible. F 23 2.5 months
6/25/2007
 5  birth control brief spotting, annoying at first, but it never returned i've had very little problems with the shot since i've taken it. i've gained weight, but i've had problems with that way before i started taking it. i can't say that i'd recommend it to anyone because not everything is suitable for everyone. i didn't have any problems before taking it and my body's adjusted to it since. not everyone's body will be right for it...and all side effects aren't necissarilly caused by the shot, some people might've had previous problems to begin with. so far, it's only benefitted me. F 17 3 months
6/23/2007
 1  Birth Control An inability to be objective, Severe and passionate mood swings that are retrospectively embarrassing, No period the 1st year, Bleeding only after orgasm the 2nd year (that was a fun answer to field from my newly-unvirginized boyfriend), Acne, and Extreme depression. The change of weight that everyone experiences on this drug has everything to do with how depression effects your appetite...I went from 120lbs to 160 (that's 6 dress sizes and 2 bra cups - maybe I should add back pain?). I found this website out of curiosity, because the period of time I spent on Depo-Provera was a memorable one. It was 4 years ago, and I took the injections for 2 years. I have a motto for Depo: "please, no." Okay, I just came up with that. But I do discourage anyone considering or taking it to look for another option. I chose Depo-Provera for birth control because I had never taken daily medication in my life, I'm a little absent-minded, and I planned on having lots of sex in my first long-term relationship. I went on the pill once I realized that my hormones were whack. It was difficult to recognize in my state, which is why I want other women to read this. After a few months off of Depo, I started to see things more obectively. I lost weight, I wasn't as depressed, and when I looked back at my actions through the entire period, I was a little shocked by my behavior. After 5 years of manipulating my hormones and, I have to say that I highly recommend rubbe F 25 2 years
6/22/2007
 4  So i don't become Pregnant they are very little or none some times... The biggest thing was becoming use to not having a period regularly... F 18 1 years
6/20/2007
 1  Birth Control Depression, Anxiety, Nervousness, mental confusion, loss of libido, overall feeling of hopelessness I was a perfectly healthy person before starting on depo. Now I wake up every morning with anxiety and nervousness. The only time I feel good (I think) is when I am sleeping. The med has interfered with my everyday life. I can't concentrate and I can't shake this feeling of hopelessness. Definitely not continuing on this med, no more artificial hormones for me!! Doctor attributes my anxiety level to my four kids, but I wasn't like this with three kids and I felt great before starting this. F 28 9 months
6/20/2007
 1  Missed Menstrual cycle low body fat Horrific - depression, terrible headaches, hair loss, stroke like symptom, early menopause symptoms, clotting, loss of mental acuity - this stuff is POISON & should be illegal. It ended my career, my relationships & took away my sense of self. POISON - Don't take it - The effects have been permanent - over 10 years! F 51 1 days
6/18/2007
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 3  Decrease Extreme Vaginal Discharge soreness at injection site, spotting for 2+ weeks WORKS AWESOME AT COMBATING THE LOADS OF CERVICAL MUCUS (WITH ODOR) I WAS EXPERIENCING FROM CERVICAL ECTROPION. F 30 14 days
6/17/2007
 2  Birth Control Hard to control weight. I had always had a problem with my weight so I did not think much at the time. After the first shot I pretty much bled (not hard) every day for 1.5 months. I tried the second shot and the bleeding stopped. I decided that due to my age and that I smoke I better stop birth control all together. So I was on it 1 year. Since then, I had to be on a 3 month leave from work because I had an emotional breakdown! I never put 2 and 2 together before I saw all of this depo info, by accident mind you. Maybe it is what caused it! Beware! F 36 1 years
6/17/2007
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 1  Birth Control Pain during intercourse, slight loss of libido My nurse, doctor and consultant were all surprised by this side effect, saying it was something they hadn't encountered before and initially tried to attribute it to lack of lubrication, although this was not the issue. Have also put a little weight on despite considerably improving diet and exercise regime. Having no periods was good, but lowering of mood, increase in sweating, body odour for the first time in my life was not worth it. Been off it for 6 months now and the primary symptom of pain during intercourse has not yet subsided. Hoping (really hoping!) it will go over the next 6-12 months. On a recent trip to the doctors I heard (with no names mentioned) another patient had had similar difficulties with her contraceptive that week - I was surprised as I had no idea these issues were so common, until reading this page. F 25 6 months
6/17/2007
 1  Contraception I had experienced many NEGATIVE side-effects including, but not limited to: abnormal periods (some lasting up to 2 months), upset stomach, diarrhea, fatigue, nausea, NO sex drive at all. This contraception method was not worth the hassle. Every day I had an upset stomach, no matter what I ate, even water didn't agree with my stomach. I was afraid to go out anywhere because my stomach was always upset and I was afraid of being in the bathroom the entire time. I had gotten ultrasounds and X-Rays done on my stomach, but Im was suspected to have some kind of stomach condition. A week after being off Depo, my stomach wasd already much better and felt normal like it did before I went on the drug. I also just switched backj to the pill...Triphasil 21. When on Depo Provera, I had absolutely no desire to have sex at all. Of course that had an effect on the relationship between my boyfriend and I. I was always too tired to have sex especially being a full time worker as well. I think I had sex like 4 times every six months, and that was mostly because I didn't want my relationship with him to end. The first summer I was on Depo, I had a two month-long period, which any w F 20 2 years
6/17/2007
 1  birth control acne, weight gain of 50 pds., depression, mood swings, eat 3x's what i used to, headaches, backpains, leg cramps, abdominal pains, blured vision, dizziness, hair loss, chest pains, and lack of sex then when I did have sex it hurt. F 22 2 years
6/17/2007

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