COMPAZINE Reviews (PROCHLORPERAZINE MALEATE)

Average Rating: 1.2 (501 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS VERTIGO MOTION SICKNESS VOMITING

 Type: Brand name discontinued; available as generic

  

COMPAZINE  (PROCHLORPERAZINE MALEATE):  This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment). Prochlorperazine belongs to a class of drugs known as phenothiazines. This medication is not recommended for use in children younger than 2 years or in children going through surgery.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on COMPAZINE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR COMPAZINECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Migraine headaches given in E.R.... Terrible! I thought I was losing my mind. When I got home from the er I couldn't sleep I had a series of panic attacks. I couldn't control my muscles and the doctor keep saying "well we can't give you anything else"! I wish I could give the damn shot to her! F 40 1 days
3/26/2016
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 1  Migraines/Dizziness Panic attack, more dizziness, passed out, jittery, wanted crawl out of my skin, drop in blood pressure. I CAN NOT BELIEVE THEY GIVE PEOPLE THIS MEDICATION! I was given this through an IV and it was a compazine cocktail. I started to rip out my IV out, I had an induced panic attack from this medication. So they gave me a sedative because I literally wanted to crawl out of skin, it is the worst feeling I have ever experienced! It is day 4 since I was given this medication and I am still jittery and I am still having panic attacks I was given a prescription for Valium to help with these feelings, it indescribable the way I feel. Now I refuse to go to a hospital ever again, I will only see my family care doctor. I do not wish this on my worst enemy! M 21 1 days
1X day
3/22/2016
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 2  For Crohns related nausea Didn't notice any strong side effects other than dry- mouth. This medication simply did not work for me to alleviate nausea. I tried taking compazine for (3) days with no relief. My doctor had me discontinue compazine & prescribed zofran which worked wonderfully. F 42 3 days
10 mg
3/16/2016
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 1  Dizziness - moderate vertigo Increased dizziness, felt worse than before. Dry mouth, anxiety, tiredness/fatigue, just wanted to sleep, didn't want to do anything. Disturbed sleep, woke up in night and couldn't get back to sleep Prescribed Stemitil - Prochlorperazine maleate 5mg three times a day for vertigo. Dipping and swaying feeling, not spinning sensation but feeling off balance, even sitting still. I woke up with it one morning. Doctor tested me for Epley maneuver but said it wasn't crystals inside ear canal. I suggested Stemitil because it worked for me 30 yrs ago when I had extreme dizziness and nausea from a damaged inner ear after a road traffic accident. Ive had dizzy spells come and go over the years from my ear damage. I haven't had dizziness for many years so I thought the tablets would help me like they used to, but now I am menopausal and my body has changed. I only took them for 3 days but the dizziness got much worse so on day 4 I stopped taking them. I felt anxiety, dry mouth, exausted, and more dizzy. After researching online I am now trying sublingual under tongue methylcobalamine vitamin B12 high dose but I need to try it for a few weeks to find out if this will help reduce my vertigo. F 56 3 days
5mg 3X day
3/11/2016
 1  6 day migraine Went to chkd after going to a regular ER they gave me the migraine cocktail as soon as they injected the compazine into my IV my heart was pounding i was sweating I couldn't stop moving my legs i felt like i needed to rip my IV out and just run as far away as possible. After about 15 mins i calmed down but my body was still twitching uncontrollably and it's been about 4 days since i got the "cocktail" and I've been having very strange dreams and my vision has been all out of wack. NEVER take this. F 16 1 days
10 mg
3/5/2016
 1  Severe Migraine I was given this drug via IV in the emergency room for a severe migraine. It was the absolute worst feeling in the world. I felt like I was going to die, and I wanted to rip my IV out and run straight home. I was exhausted but couldn't sleep because of the severe anxiety I was having. This medicine was not worth the fact that it got rid of the migraine PLEASE DON'T TAKE THIS F 16 1 days
1X day
2/24/2016
 1  nausea My husband was given IV Compazine for nausea. Almost immediately he became severely anxious, and his heart rate rapidly increased and he began sweating. He is not an anxious person and this was extremely out of character. He told me he felt like he was going to die and begged me to help him! He also had feelings of paranoia that he's never had before. The nurse gave him some Ativan to counteract the results and he was able to get calmed down slightly. However, now 2-3 weeks later he has been up several times in the night still experiencing the same side effects. He never experienced this prior to taking Compazine! DO NOT Take this medication! M 43 1 days
1X AN
2/21/2016
 1  Stomach virus. (5 days) While not being able to hold down any food for days,....my stomach started hurting very bad. I couldn't take the stomach pain anymore. Called mom to take me to the E.R. I know I lost 10 lbs that week, and shouldn't have waited THAT long! I was admitted & they gave me some phenegran thru I.V. My stomach was still hurting very bad,...it didn't help at all. They then gave me this horrid Benedryl/Compazine cocktail. The next thing I knew I felt like I was suddenly going to die. I wanted to rip my I.V. out right then and there. I thought about it, and didn't say anything to mom or the nurses,....but nothing but bad thoughts entered into my mind. I couldn't stop thinking about taking that I.V. out myself though. I'd never experienced anything even close to this before. I dealt with it on my own, was released from the hospital as it did eventually work, & the bag of I.V. fluids did help as well. .......was then dropped off at my house and continued thinking/feeling M 33
? 1X H
2/1/2016
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 1  Migraine and nausea I was given a cocktail of benadryl then compazine and fluids due to a migraine I had for 2 weeks. At first I thought the crazy feeling was just me as I deal with anxiety anyway. In the next week I experienced random attacks of impending doom, like I was going to die. WORST feeling ever! I ended up back in the ER shortly after (still had migraine/nausea) and was given same cocktail. I wanted to rip out my iv and run. I knew then it was from the compezine. The only thing that kept me there was knowing I was getting a dose of valuim (which hardly helped the impending doom feeling) for my brain MRI. After reading these comments I regret not telling the nurse right away how I was feeling. Other than the impending doom I also felt trapped, like I was never going to leave that hospital room. I was so tired and wanted to sleep but felt like I would never wake up if I did. The "cocktail" did make me feel better temperaily but I can't say that it was worth it. I would rather stay puking my guts out with a pounding migraine then feel like that ever again! I suggest you please tell your nurse or doctor right away if you have any negative symptoms of compazine! F 1 days
1/9/2016
 1  Severe Migraine Extreme anxiety for entire 48 hrs Panic attacks + shakiness Insomnia Difficulty breathing Dear hospitals, PLEASE for the love of God STOP giving this POISON to your patients! I was given this garbage for a severe migraine and within seconds I was shaking like crazy and I had the worst anxiety of my life for 2 whole days. I couldn't even sleep it off because it was preventing me from sleeping and at one point I was even having trouble breathing. It didn't even work for the pain I was in, it only made me feel like I was going out of my mind. To make matters worse, the nurse gave it to me even when I asked her not to, and then told me to stop freaking out while I was having a panic attack. Always make sure that you ask your doctor or nurse what they are about to give you. Don't let yourself or your loved ones get injected with this panic poison!!! F 23 1 days
10
1/8/2016
 1  Concussion I wouldn't wish this drug on my worst enemies. I've never been suicidal in my life before this. It's been over 72 hours since they shot me up with it in the ER, and I'm still not focusing the same. I'm listless in my desires, but man, I couldn't even sit still. I looked like I was crazy. The only thing that's helped is Klonopin. F 26 1 days
5mg/mlx100 1X day
1/6/2016
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 1  Nausea/vomiting I was young, 12 or 13. Was given a shot in the buttocks at the ER. That was the most painful injection I have ever had in my life. 24 hours later I could not relax my stomach muscles and began feeling jittery like I had to run away. My mother took me to the clinic and while sitting in the waiting room my mouth turned into a grimace and my tongue protruded out, heart was racing. They rushed me to an exam room and while lying on the table my back arched to the point that the only thing touching the table was the top/back of my head and my heels. My tongue came out and curled down my chin. I remember the Doc coming in and ordering the nurse to get Benadryl shots stat! After the B shots(s) I was able to relax and felt better after a few days. Prior to this reaction, I was very outgoing, loved to get up in front of the class to read my stories, do speeches or just clown around. Afterwords I was withdrawn, anxious and started suffering panic attacks. The rest of junior high and high school was hell! That was in the late 70's so you didn't talk about your fears. There are no panic disorders or any other type of mental illnesses running in my family so I just suffered for years until seeing a shrink and getting on some mild meds around 1999 or so. After reading all the experiences of others, I am convinced this drug affected a big part of my life. My anxiety was so severe it kept me from furthering my education. The good news is, it does get easier over time and I never ever had a desire to do drugs because after that reaction it took several years for anyone to even get me to swallow an aspirin. LOL! I noticed on some of the comments that people have a desire to correspond with others about their experience. I would be very interested in that myself and am leaving email address. I f this drug is still available, do not take it! M 53 1 times
Unsure 1X O
12/8/2015
Email
 5  Migraines I have suffered with terrible migraines for years now neurologists, amitriptyline, fiorecet, MRIs, CAts, the works. Went to EC last weekend after fiorecet and phenergan failed and I was vomiting green bile and drooling. The IV compazine, benadryl, toradol, steroid cocktail worked immediately. I did experience the flight stage and wanted my IV out. However, it ended the pain, nothing else mattered. I fought the irritability and went to sleep. I could not work or drive the next day. After that I was fine. I take the oral form of compazine now with benadryl and pain meds for migraine and it's working so far. Good luck to all you other migraine sufferers. I pray for us all to be pain-free. Careful with IV use F 32 7 days
10mg
11/7/2015
 1  migraine I have to say that I know now that giving someone compazine IV without pretreating them with a beta-blocker and ativan is just asking for trouble. Unfortunately, at the time I didn't know and sadly they usually don't tell you what they are giving you. Some doctors absolutely refuse to treat anything but obvious pain (broken bone, bad burn..etc) with opiates. It turned out I was given a large push of straight compazine and about the same time the nurse left I started feeling burning and jitters. I then felt waves of tingling coursing up my body. I started to feel restless and anxious as if something bad was happening and then I started to cry. I don't know why but I just knew I must be having a reaction to the medicine and that I could very well die. I slammed the emergency button and the nurse came in and said it was just normal side effects. ?? wtf, I was freaking out and going out of my mind but how can you relate that? I now know I did have a reaction but that it precipitated an anx Terrible drug, I know it has it's uses and if given orally or as a injection into the arm or butt that cuts down on the side effects a lot, but just hearing that drugs name scares the crap out of me. M 50 1 days
? 1X day
8/23/2015
 1  Nausea, dizziness Dry/stiff tongue, restlessness, muscle spasms, seizures A couple hours after taking compazine I was fine then I started to notice the sides of my tongue wouldn't move while was talking I didn't say anything at first out of embarrassment then about 45 minutes later I had absolutely no control over my throat or tongue and I could barely breathe so my father called an ambulance and I was sent to a hospital an hour away from where I live since I am only 14 the emts did not want anyone riding along when I got to the hospital none of the nurses or doctors had been told abouf my arrival and since I couldn't talk none of us could make any since out of what was going on and luckily my oldest sister who lived near the hospital showed up and talked for me I layed down on the hospital bed and my older sister who was studying to be an emt noticed that my blood pressure was high just then I went into what the nurses thought was all me making it up a seizure while I was fully conscious Then when they realized I was not making this up they put me on an I.V and gave me a large dose of Benadryl which put me to sleep in less than 10 minutes the doctor did blood work and then found compazine In my system I would not in courage anyone to ever to take this medicine F 15 1 days
8/9/2015
 1  Migraines Went to ER to get some relief from a three day migraine... They gave me a mixture of compazine, Toradol and Benadryl.. Within in 5 minutes I was begging for help , pasing back and forth couldn't sit still. they made me wait 20 minutes then gave me more Benadryl.. That helped for a few minutes but the jitters started to come back so the gave me Ativan that finally helped... I felt like I was going insane!!! I have added this medicine to my allergy list! F 34 1 days
10 mg
7/20/2015
 1  migraine Was given compazine via IV at ER twice 2 different days for migraines and 2weeks later still having horrible side effects, such as seizures lasting 30 minutes waking up NOT remembering anything my parents having to call 911 several times. This medication should be of the market. Compazine is a HORRIBLE medication M 17 2 days
10mg IV
6/27/2015
 1  nausa- 5 day migraine I walked into the hospital and I described that I had a nose bleed I got a headache then migraine then felt like I was gonna pass out they took me straight back they pulled my blood took my pee and then set a iv in me she said I'm gonna give you a migraine cocktail and they was making me sign papers my head hurt so much i couldn't read anything so I signed everything off thinking these ppl can only help me so she shoots the riddlin benodryl and thraxin into my vein my heart beat went out of the roof crazy and i was literally holding my head holding my self from screaming i was moving all over the hospital bed i even layed the opposite way it was impossible to get comfortable then the room started spinning and I was feeling like I needed to pull the iv out and run home I didn't drive so I called my fiance telling him what was going on and he told me to stay an stay calm so he talked to me until I was so drowsy I could barley hold my eyes open or even talk and then I came home and slept for 16 hours straight Its a f*ing psyco drug you will go insane it didn't make my headache leave and I wouldn't want no human to take this it shouldn't be legal its probably as bad as illegal drugs it makes you comfortable with committing suicide or killing someone you cant think at all F 19 1 days
1
6/23/2015
 1  nausea Felt crazy and very anxious the first dosage was ok but second was too much in er room be careful it was in iv M 35 1 days
6/18/2015
 1  nausea when I was four and a half months pregnant and feeling nauseated went to ER hooked up an IV give me compazine without telling me instantly felt crazy like I was losing my mind gave me something to reverse before they gave me the compazine they check the baby's heartbeat everything was fine after the reaction did A ultrasound and they said the baby died. Two weeks later I hemorrhaged and almost died. DO NOT! take this medication ever. have never felt a hundred percent normal sense. lots of anxiety still. F 28 1 days
6/8/2015
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