COMPAZINE Reviews (PROCHLORPERAZINE MALEATE)

Average Rating: 1.2 (501 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS VERTIGO MOTION SICKNESS VOMITING

 Type: Brand name discontinued; available as generic

  

COMPAZINE  (PROCHLORPERAZINE MALEATE):  This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment). Prochlorperazine belongs to a class of drugs known as phenothiazines. This medication is not recommended for use in children younger than 2 years or in children going through surgery.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on COMPAZINE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR COMPAZINECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Severe headache Was given compazine and Benedryl IV push in ER. I immediately could not breathe and pulled out the IV catheter, blood pressure cuff, and pulse oximeter probe off and ran into the bathroom because I simply could not breathe or calm down . My skin was bright red and I literally thought they were trying to kill me . Needless to say, the staff never noticed the difficulties I was experiencing and the Doctor chuckled when he was told that this had happened to me . He stated “ Oh yeah, about 1 in 10 patients experience that reaction “. I honestly believed they were getting their kicks from torturing me . My headache remained for the next 4 days and I didn’t sleep for days . This drug combo is harmful . I think it should be banned from its use . My regular physician said the same thing as the ER doctor and kinda acted like I was exaggerating the episode . I won’t be returning to her office either . In the future , I will ask about potential side effects before I ever allow a drug to be administered to me or my loved ones . Like some of the others that have posted here , I have had several residual panic attacks since the one time injection of these substances . I WOULD RATHER DEAL WITH THE HEADACHE AT HOME THAN EVER HAVE THIS DONE TO ME AGAIN. WHO KNOWS, NEXT TIME IT COULD KILL ME ! F 44 1 days
IV
9/30/2017
 1  Migraine relief Severe anger My daughter, 15, took the medicine, She was originally given it at the hospital-we went in due to severe migraine. She got very upset, tried to pull out her IV, yelled at me. At a later date,Neurologist then gave it to her (long story). Within 30 minutes, my daughter ran into my room out of the blue, and started breaking furniture, throwing things around my room, and then ATTACKED ME. I yelled at her to get her to stop. It was like she woke up from a dream. She said "Mom, I'm scared" and started crying. This medication is beyond horrible. Take it out of the doctors use at once! F 15 1 days
1X day
9/10/2017
 1  migraine WORST EXPERIENCE EVER! i received compazine through an IV, for a migraine in the ER. as soon as it went in i felt pain throughout my whole entire body. mainly my legs! i started feeling my heart racing and decided to tell the nurse and she didn't even budge. i felt so out of place and started feeling so overwhelmed and uncomfortable. i started getting really thirsty and constantly asked for water. i got discharged 30 mins later. still feeling like something was wrong my parents decided to come over my home to check on me and right away started feeling my head tilt back , uncontrollable movements, teeth clinching. they then rushed me to a different ER , and was told i was having a dystonic reaction and was given benadryl to counteract the compazine. i eventually knocked out! the next two days i wasn't able to sit still. had felt like i'd been hit with a car! ive gotten ready as depression, anxiety, irrational thoughts and no sleep! ive started seeing a psychiatrist to try and get my life back to normal but its been so hard! my family is thinking of suing the hospital because they have caused me a lot of damage. ALL I WANT IS MY LIFE BACK! HATE THIS DRUG! DONT RECOMMEND! F 25 1 days
iv
8/22/2017
Email
 1  Headache Went to ER for severe headache and was given Compazine and Benadryl. I felt burning sensation in my throat and chest. I felt so nervous and jittery and thought I would never get rid of that feeling. Headache subsided, but could not rest or sleep. Nurse gave me more Benadryl. I stayed awake for 2 days straight, with feelings of anxiety. Never again. #bancompazine F 37 0 days
8/21/2017
Email
 1  Nausea for pregnancy Compazine give your brain a scar like won you would have if you git burned in a fire it's like a psye scar. I was pregnant and I noticed the feelings I had of anger,hurt confusion,and mania. And,noticed it in my baby. What a nightmare we have been living I think the should pay for ruining our lives. Don't take this it is the stuff of nightmares! This should be banned!!!!!! This a drug they are irresponsibly handed out especially to pregnant women I beg you to be aware. F 48 1 days
?
8/13/2017
 1  Migraine I was given a compazine in my Iv for my migraine....I continuously hit the call button . I couldn't be still and had a panic attack . Nurse came in as I was trying to rip the Iv out and added Benadryl which knocked me out. I will NEVER take that crap again. F 36 0 days
8/13/2017
 1  Migraine Was given this medication at hospital for A migraine. Within seconds I jumped out of bed and began trying to take IV out of my arm. I was pacing and telling my husband I needed to get out of there. For the first tie in my life I felt I was losing my mind. I only got about 2 hours of sleep that night. My mouth also became extremely dry and lips began to be dry and developed small scabs. It's a week later today and my mouth and lips still feel weird. Taste buds are off and tongue burns when I eat or drink. My headaches are worse, chest pains and still jittery. I don't feel the same at all. The hospital should be required to explain this medication and its side effects before giving this to anyone. They should also be required to provide you in writing what drug was administered and side effects before you leave. This is terrible!! F 44 1 days
8/12/2017
 1  Migraine Immediately I felt like ripping the IV out, it burned and was painful at the site. I felt doomed and severe panic. I kept getting up and asking for water. I was too afraid to tell anybody what I was feeling. I was discharged from the ER about 40 minutes later. The car ride home and the rest of the night were terrifying. I literally thought I was going to have to be admitted to the psych hospital. I paced all night, couldn't focus, couldn't relax, couldn't sleep, couldn't breathe and couldn't eat. This was the worst experience of my life. The effects have worn off but I still have anxiety about taking any medication that would alter my thought process. This medication was given with toradol. I would never take this medication again. F 44 1 days
10mg
8/3/2017
 1  Migraine Drove me crazy!!! I could not breath and I could not sit still. My oxygen level dropped into the 70's. I hate it!! F 1 times
20
8/1/2017
 1  Nausea I was given this medicine in the e.r. and immediately my eyes wouldnt quit twitching uncontrollably..I informed dr and they told me it was normal and was just getting sleepy. They wheelchaired me to car. Hubby taking me home..we live 6 min and on way hm..I told my husband somethings not right..I got hot burning sensation in chest..pulled up at hm..got out of car..couldnt walk and fainted..I was out for a good minute..sweating pale..when ambulance got there..my blood pressure was 70/40 took me back to ER where I spent 3 days in ICU trying to get blood pressure normal. Today is day 7 since they gave me meds and I still am not feeling well. I have massive headaches..dizziness..nauaea..tired..They said I am allergic to this medicine but it should be out of my system by now. I am never sick and I cant even function now. Do not take this medicine. F 39 1 days
10mg
7/31/2017
 1  Migraine Went to ER and treated for migraine with "migraine cocktail" which I later found out contained comprazine. Within minutes of IV, severe anxiety set in. I felt like I just needed to rip the IV out and run away. Nurses had no clue what was wrong, doctor instantly recognized problem and administered benedryl. That was 2 days ago and the anxiety has not completely gone away. Also, I feel like I can't breath. Has anyone else experienced this? I just want this to go away, I feel like it's terminal. What an awful experience, I can't believe the nurses had no clue. Please don't take this drug! F 39 1 days
?
7/28/2017
Email
 1  Migraine DO NOT RECOMMEND. It made me want to crawl out of my body, want to rip the IV out and run away, made me want to die, anxious and nervous and jittery and restless. My heart pounded on my chest. It also affected my movement and was hard to move. I have it on my file that I'm allergic now. The side effects lasted for 2 days, I didn't feel myself. My friend had to come over and stay the night with me because the anxiousness feelings kept coming up in waves. Given once in ER for migraine cocktail F 22 1 days
7/18/2017
Email
 1  Nausea in the ER I received an arm injection about 4 days ago and my upper arm has been in EXTREME pain ever since. The medicine also made me feel very uncomfortable/jittery. I had a hard time going to sleep. I don't know if the nurse went to high up on my arm or what but this pain is terrible. I never heard of compazine before but I will NOT be taking it again!! RECALL!!! F 30 0 days
7/5/2017
 1  E.R I went into the e.r due to a massive panic attack I had all day when I got there they gave me fluids and a malox cocktail bc of the nausea and also wanted to give me promethazine however I explained I couldn’t due to my current medication so they administered compazine instead which id never heard of. What a freakin nightmare! I thought I was beginning to calm down but I got the sudden feeling that my skin was crawling especially my legs bc I was so drained from my long day of panic attack I fell asleep for 10 minutes and woke up in horrible jitters and insomnia I begged them to help me so the nurse said they can give me benedryl but I thought it would make me worse so I passed. When I went home I finally got some on and off again sleep today it is 3:30p.m and I still can feel the effects not as bad but it is there and makes it hard to focus on my day. This needs to be banned immediately or researched and revised. Please!! Never will i have this in my system ever again. Beware F 28 1 days
1syringe
6/8/2017
Email
 1  Migraine and nausea Horrible anxiety - uncontrollable shaking - perceived inability to breathe- tightening of the throat - extreme fear This drug needs to be removed from the market. This drug should NEVER be given to a patient without warning of side effects. No one would want this drug knowing the side effects. F 49 1 days
10 MG IV
6/3/2017
Email
 1  migraine restless, anxious, severe panic attacks this med should be banned from the medical field period. I had severe panic attacks for 4 -5 days after taking it! F 31 1 days
5/16/2017
 1  Migraine & Nausea I went to the ER with a bad migraine with the desire to get a CT scan for it. I got one, and they gave me Compazine and Benadryl through an IV drip afterward. The Benadryl did not even remotely help me. Instantaneously after the Compazine went into my arm, I got a burning, hot feeling around my heart that spread down the rest of my body. I was shaking violently, getting cold and hot at the same time, could not focus on anything, and I was sweating profusely. It has been one day since this drug was given to me and I have had two violent panic attacks since. Six hours after I went home from the hospital, my body seized up until my hands and legs could not move and I was barely able to breathe. We called an ambulance and they were able to bring me back down over the course of an hour, but I was trembling the rest of the night and could not sleep. Nine o'clock this morning, I seized up a second time and was hyperventilating uncontrollably for an hour. We went to the hospital and I was only able to calm down and breathe again and move my hands when they gave me Xanax. My chest still feels heavy, my heart hurts, I have constant heartburn and a burning sensation in my throat. I would much rather have migraines and nausea for days at a time than ever be given this drug again and I will refuse it if they ever try to administer it once more. Why in the world is this drug on the market? F 17 1 days
Unsure
5/12/2017
Email
 1  Migraine WORST EXPERIENCE OF MY LIFE. Went to the ER for a migraine. Was given Compazine in an IV. Within 15 minutes, I felt like I wanted to die. I wanted to leave the hospital and rip out my IV. My mouth was so dry and I couldn't sit still. I don't know how I drove myself home. It's been four days and I still don't feel back to normal. I wish I could sue the ER doc that gave me this. F 50 1 days
1X day
5/9/2017
 1  migraine Reglan, phenergan and ativan also give me that panic feeling. It's called Akathesia and if it ever happens again, have them give you Cogentin and a couple of xanax and it will disipate within 20 minutes. They tried the benadryl route but did not help me at all. They kept telling me to sit still but it was impossible. Finally a med student came up with the Cogentin and I keep it written in my phone. Worst feeling ever! I remember having crazy thoughts like wanting to jump from the car on the way back to the ER. Totally irrational thoughts. F 45
1X day
5/5/2017
 1  nausea due to pelvic radiation sleeping more than 20 hours a day. Couldn't wake up. Couldn't stop moving my jaw or legs. While I was sleeping others observed my legs and jaw moving. Doctor told me it usually only happens in the elderly. It took days for the symptoms to go away after I stopped taking the medication. F 32 2 weeks
1X day
5/1/2017
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