COMPAZINE Reviews (PROCHLORPERAZINE MALEATE)

Average Rating: 1.2 (501 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS VERTIGO MOTION SICKNESS VOMITING

 Type: Brand name discontinued; available as generic

  

COMPAZINE  (PROCHLORPERAZINE MALEATE):  This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment). Prochlorperazine belongs to a class of drugs known as phenothiazines. This medication is not recommended for use in children younger than 2 years or in children going through surgery.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on COMPAZINE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR COMPAZINECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Migraine "cocktail" -"need to run" -restless legs -anxiousness -chest pain (mild) I didn't realize this med had this side effect, but moments after getting it i was impatient and needed to leave. Now I'm home almost 6 hours later waiting for it to run its course. My migraine was sever enough I'm relieved that it worked and now just hope the side effects have peaked and won't prefers from here. Wouldn't use again though. F 24 1 days
5mg
5/15/2015
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 1  NAUSEA Hands very shaky, took in pill form, trouble controlling fingers, headache, night sweats, frequent urination, rapid heart rate. I was taking the generic version of compazine (prochlor??) (I have since thrown it out). This as given to me for nausea. Worst drug ever (well close tie with prednisone) F 63 5 days
10 MG 1X AN
5/6/2015
 3  migraine w/vomiting I first had this drug IV for migraine and vomiting... started having the worst anxiety ever... I couldn't breath and needed to get out and go...that was about 10 years ago.. my Dr has written me a prescription for it t take by mouth. I do not get the serious side effects from it that I had from the iv form.. just FYI to you guys that say you won't take it again... F 30 1 days
10mg
4/10/2015
 1  Migraine This drug is absolutely awful. Within minutes of the nurse administering the IV, I felt a sudden panic. I felt like I needed to get out of the hospital immediately, like I was trapped and was never going to get to leave. I became extremely agitated and demanded that the nurses remove my IV so I could leave. I thought once I got home, the anxiety would be gone. I was wrong. I was anxious the rest of the evening along with feeling foggy, disconnected and having thoughts that nothing would ever be okay again. It has been 24 hours since the IV dose, and I still feel very anxious and disconnected. I would tell anyone to NEVER take this drug. I would suffer a dozen migraines before ever taking this drug again. It should not be allowed on the market. F 28 1 days
1 IV Dose 1X day
4/10/2015
 1  Migraine This drug is HORRENDOUS! I was told that any side effects would last only a few hours after leaving. The side effect of this medication were worse than the migraine. It took 48 hours for the effects to diminish. Within 10 mins.of it being administered I was restless, fidgety and exhausted at the same time (which is a terrible combo). Once I got home (which by the grace of God, I was able to drive myself home...which I should not have been allowed to do) I couldn't sleep, yet was too groggy to stay up. I lost my appetite and urinated incessantly! I mean I must have peed every 1 1/2 hrs. It stunk really bad too...for about 3 or 4 days. I had jaw clenching that was so bad that my jaw was sore for almost 4-5 days after the injection wore off. I took about a week for the restlessness to dissipate. Still having trouble sleeping almost 3 weeks later! After the 48 hour period...the migraine came back for almost two more days! I am a spiritual person and believe that life events can shape us This drug SUCKS! F 1 days
IDK 1X O
4/9/2015
 1  migraine in ER 14 weeks pregnant I told the doctor, that I was allergic to REGLAN. He came in and gave me Compazine. I felt ok for 10 min, and then the unbearable sensation hit me. I felt like I was dying. It hurt so bad. I tried ripping my iv out and then decided against it. I then rang the call button 5x to get a nurse in, and told her I was going home NOW! Worst feeling of my life. Still feeling it a day later. I want my old body back! Do NOT take this med!! It needs to be banned. F 24 1 days
1xD
4/9/2015
 1  migraine Wished I would have found this site before my migraine. I had a 4 day migraine that was unrelenting. Vomiting, loss of vision left eye, hearing problems. Went to ER to just find some relief to get comfortable, COULD NOT HAVE BEEN WORSE!! 1ST time I had this cocktail. I already suffer from panic attacks, especially with any morphine/opiates. Within 5 min of the IV cocktail- full blown panic attack. Crawling out of my skin to get up and walk around- in way too much pain to do it. After lying there for another few minutes felt like a heart attack was coming,just wanted to get out of there and get that IV out of me. I was in such a horrible panic attack I ripped my IV out and ran out of the ER. Will never get this cocktail again!!! F 38 1 days
4/8/2015
 1  vomiting Wanting to stop taking pill Can I go cold turkey off them F 56 4 years
10 mg
4/6/2015
 1  Nausea & vomiting I became someone else over the three days a huge, college/learning hospital gave it to me I knew I didn't care for the way it made me feel within minutes of getting it, but that was a small price to pay to stop vomitkng by day two I wasn't sleeping, very nervous, not thinking clearly all the time, etc. no one ever put it together. By the third day I had convinced myself I was loosing it. I had social anxiety symptoms, the feeling I needed to get out of the room I was in and then just keep "escaping" is the best way I can describe it. I couldn't function because I was so agitated, insisting on leaving (which I finally did by that evening)....just a bunch of different symptoms that were not easy to deal with. They finally gave me some Benadryl and then some Ativan to calm me down. I was being treated as though I was just a random crazy lady who was just f.ed up. They had psychiatry come talk to me (3 different drs at three different times) who all said there's nothing wrong with your mental status at all....the medical team just needs something to blame your symptoms on and this time this won't work for them. I left AMA that evening & went to a different hospital for the rest of my inpatiet time. Once the compozine had been flushed from my system I was back to normal. I seriously would have slept on a bench in a park in a bad neighborhood next to a crazy homeless guy than to stay there one more second. My mind was on overdrive and rational thinking was non existe F 42 3 days
30mg
4/2/2015
 1  Migraine I went to the E.R for my first ever migraine. Dear god, do I regret it. I had a panic attack, I was in hysterics, I wanted to cry and scream but I couldn't even produce any tears. I didn't attempt to take out my IV, but I know for a fact I wanted it out and I wanted to go home and rest. I tried to fall asleep on my hospital bed after I calmed down a half-hour later, I couldn't go to sleep because I was too hyper vigilant of sounds. Then I started getting tremors. By the way, this was in a cocktail with Benadryl and some other drug I can't remember, but seeing all the reviews here made me think Compazine made me freak the fuck out. M 17 1 times
idk 1X day
4/1/2015
 1  headaches due to viral meningitis I was given this medication while in the hospital for viral meningitis. Gave me the worst anxiety attack of my life! I still have anxiety attacks from it. I later discovered that this medication, when given through IV, is supposed to be given extremely slow, over about 5 to 6 minutes. It had been given to me in a 5 second period... F 28 1 times
1X day
3/29/2015
 1  migraine/vomiting horrible restlessness! just like these other people prescribe! Benadryl did help, though. whew! F 63
1X day
3/21/2015
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 1  Nausea Absolute HORROR. OMG WORST FEELING EVER!!!! Complete PANIC racing heart chest pain... Such Torture for 3 days after just one IV dose of compazine They gave me Benedryl just made it worst I couldn't sit still. Up and down literally every 5 minutes also had to pee every ten minutes . Feel like I couldn't breath couldn't swallow. Couldn't barely talk. Couldn't function. I felt in complete state of terror .... Idk what is wrong with. Doctors and nurses saying they can't do nothing more then give Benedryl ... Absolute bullshot Give me Xanax Valium Ativan. Something!!!!! Calm a person down. My heart rate was through roof. I was shaking Worst experience F 28 2 days
3/19/2015
 1  Migraine This drug is horrible!!! I went to the ER because I was experiencing the worst migraine of my life. Within 10 minutes of the compazine being administered through the IV I felt extremely restless. The nurse offered benadryl but I just wanted to go home at this point!! I was discharged then had to wait about 30 minutes outside for my ride because I couldn't drive. It helped the migraine but at the same time I was so out of my comfort zone. Once I got home I was still very restless. It was awful. I had no control over my body. Probably one of the worst days of my life. Finally I took Motrin pm and passed out. Felt better the next day... however it's nice to read that I wasn't the only one who had such a horrible experience. F 27 1 days
3/17/2015
 1  migraine My daughter who is 7 went to the hospital for a headache. They said it was a migraine and gave her compazine and benadryl. Immediately she started twitching and seemed to be breathing heavy. The nurse said she was fine and left the room. I had to run out and get her 10 seconds later because my daughter started freaking out, screaming saying she needed to get up. As soon as the nurses got to the room she stopped breathing. They had to push on her chest and give her oxygen. I sat there watching in disbelief. I have never been so scared in my life. I thought i was losing my baby. This drug should be taken off the market F 7 1 days
dont know
3/17/2015
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 1  Migraine Every review you read is right. This drug is horrific. Shakes, spasisms, nervousness, anxiety, for many many hours after given in IV with Benedryl. Should be off the market! F 42 1 days
1X day
3/13/2015
 1  Nausea I had what I guess was a panic attack after taking this drug. It was given to me in the hospital and I literally took my IV out of my arm and ran out of the hospital. I later found out that had I told the doctors I could have been given benadryl to mitigate the effects. I have never felt like this before or since. It was the worst feeling of my life. F 33 1 days
1X day
2/24/2015
 1  migraine Went to er because a bad migraine and left wanting to blow my head off! It wasn't ten minutes after the doctor pumped it via iv I was raising hell wanting to leave, threatening the doctor and completely out of my mind. Finally left and made my wife pull the car over and just sat on the side of the road. I couldn't get comfortable no where. Finally got home and was flopping like a fish, restless as hell. Then the frequent bathroom trips began, I peed probably 35 times that night, contemplated suicide all night also.. worse drug ever If the us government wanted to torture someone, just give them a shot of compazine... DO NOT TAKE THIS DAMN DRUG.. I REPEAT STAY AWAY!!!! M 23 1 days
2/16/2015
 4  Breakthrough Migraine None Took suppository along with magnesium, naproxen and benedryl for breakthrough migraine as directed by neurologist. No more than 2 per week. One is all it takes. No side effects the few times I have taken it over the last 3 years. F 50 3 years
25mg 1X AN
2/14/2015
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 1  Migraine Do not take this medication under ANY circumstances. I do not know why this is legal to administer to human beings. This medicine gave me the absolute worst experience of my life. I was restless, anxious, couldn't sit still, the whole she-bang. I wanted to die. I begged one of the nurses to please kill me. Did it get rid of my headache? Yes. But you'll wish you just had a headache after you experience the side effects of this devil spawn from Satan's pharmaceutical company. NEVER, EVER, UNDER ANY CIRCUMSTANCES, TAKE THIS MEDICINE. I am not joking. It will make you extremely suicidal if they do not have Cogentin on hand to reverse and placate the effects. M 19 1 days
IV 1X AN
2/10/2015
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