COMPAZINE Reviews (PROCHLORPERAZINE MALEATE)Average Rating: 1.2 (504 Ratings)Filter ResultsCompare COMPAZINE with similar:
Type: Brand name discontinued; available as generic
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 |
More on COMPAZINE: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR COMPAZINE | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | nausea after knee surgery | 24 hours after knee surgery I started to have nausea(couldn't even keep water down) so my doctor called in a script for compazine (10 mg) 1 tablet every 8 hours. After the first pill my nausea stopped but I took 1 more pill 8 hrs later for "good measure". I didn't feel the side effects until about 8 hours later. I could not focus, crying without reason, felt like I couldn't breath fully at times, extreme restlessness and rocking back and forth, panic like feeling, urge to move but coudln't due to knee surgery. I thought that I was experencing mental illness. The next day I was worst so my husband took me to the ER (they knew what it was before I told them that I had takened Compazine). They gave me IV Benadrly in ER, when home and took 2 Benadryl every 4 hrs for 4 days before the side effects stopped.It was a very scary experence because I thought I was mental. | People should be warned about the side effects BEFORE taking this drug. | F | 46 | 2 days | 10/2/2007 | 1 | nausea | Oh my God! It was absolutly horrifying! At the time I was either 15 or 16, I had nausea so my doctor prescribed compazine to me, after like 2 days of taking it this was the reaction I had. I was with my dad at a department store and he was making me laugh and all of the sudden when I was done laughing, my face was stuck in a smile. I COULD NOT TAKE THE SMILE OFF OF MY FACE! The next thing I knew, my jaw was completly crooked, I started to panic so i asked my dad for his car keys because i was embarassed to be in public. Once in the car it started getting worse and i was crying and freaking out. and that was only the beginning from my jaw then my neck went to the side, then my tongue got stuck to the side of my mouth so i couldnt talk right. then my back started to go into a backbend my arms and fingers cramped up and were getting tucked behind me. i was dry heaving and sometimes during a dry heave my body would completly relax and then it would suddenly tighten again. this whole thing | i do NOT reccoment this drug, no matter what. Id rather be nauseous any day before dealing with the side effects i experianced from taking it. | F | 20 | 2 days | 8/31/2007 | 1 | food poisoning | uncontrollable body spasms,tightness in throat,difficulty breathing,jerky body movements,jaw pinned to shoulder, slurred speech, stomach muscle spasms | I was given compazine by my primay physician for nausea and vomiting for what was diagnosed as food poisoning from hamburger meat purchased at a fast food resturant. I followed the directions on the prescription and took two 10mg pills for three days. Two hours after the last pill, my neck began to go to one side, I had extreme muscle spasms in my stomach and slurred speech. A friend called my grandmother and took me to her house and she thought I had experienced a stroke. She took my blood pressure and when it was norman she started to massage my neck and body. When this did not work,she called my doctor and was told to take me to the hospital emergency room. They immediately started a drip and gave me Benadryl. I continued to spasm for a period of time and then the spasms stopped. I stayed in the ER for about three hours and was told to take Benadryl for the next two days or until I could see my primary physician. My body ached all over and I was basically disfunctional for the n | M | 18 | 3 days | 8/19/2007 | 1 | Migraine headache | My 16 year old daughter was given Compazine through an IV to help with the nausea from a severe migraine. Within 10 minutes she was complaining of burning and pain at IV site. Within 45 minutes she was extremely restless and was unable to get into any comfortable position, she seemed almost like she was having some sort of panic attack and really could not explain what was wrong. I thought it was because she was so exhausted from the migraine pain and vomiting. We were released and she came home, fell asleep for a few hours but was worse after she woke up. She said it felt like her skin was crawling off and her limbs were tight and stiff. After a call to the hospital I was told it was from the drug and it should wear off in a few hours but I got online found this site and went right to the store and got Benadryl, she took two and within 30 minutes she was returning to herself feeling wise and behavior wise. This drug should not be taken or given to anyone without first being told of it | F | 16 | 1 days | 8/18/2007 | 1 | Nausea | I was given a dosage via IV for nausea while in the hospital recovering from a surgery. Within 1-2 hours of being given Compazine, I was completely catatonic. I mean completely—as in verbally none responsive and in a vegetative state. I didn’t know or understand what was happening to me and it felt like I was completely paralyzed. It was without a doubt the most horrible experience of my life--all from a drug that was just supposed to take away my nausea. The experience lasted for approximately 13 hours – and from what I understand it was a horrific experience for my wife and family as well—to see me basically in a zombie like state for so long without any clear indication if and when I would come out of it. This is a barbaric medicine and I cannot fathom how it has not been banned. Even the chance of this side effect is not worth it. There are better medicines for nausea. | M | 36 | 1 times | 7/24/2007 | 1 | Upset stomach from drinking | Uncontrollable body crams that started off from lower body and eventually going all the way up to my neck and face. Upper body spasms were the most painful and was almost unendurable. The side effects did not kick in until after 24 hours of the compazine injection, and began with soreness in joints and muscles. | Definitely prevent using compazine unless you are 100% sure that you are not allergic to it or unless it is 200% necessary. The extreme pain was horrifying and unimaginable until you realized you lost complete control over your own body. | M | 25 | 1 times | 7/19/2007 | 1 | vomiting | Clumsy gait, facial spasms. | My daughter was competing in a county pageant and had been sick several days. She was prescribed compazine suppositories for the vomiting. She took one the day before and one the morning of the pageant. DURING the pageant, she was unable to walk in her high heels (had to switch to short/broad heels) and had horrible, painful facial spasms causing her to grimace and twist her jaw to the side. Ended up in the ER on IV Benadryl (in her gown and sash) It worked immediately and her face finally relaxed. It was terrible timing but would you believe she still won Miss Photogenic and 2nd runner up? We had to laugh despite it all. | F | 18 | 2 days | 7/15/2007 | 1 | nausea from gastroparesis | Drowsiness mixed with jitteriness, felt like I was jumping out of my skin, vision difficulty, shakes. | It took about 18 hours from the last dose for the bad side effects to completely go away - and I still felt weak and had trouble seeing for a while after. | F | 20 | 1 days | 7/15/2007 | 1 | They told me it was for migraine! - | This medication needs to be banned for good. Everything you guys have said and (those of us who feel we seriously could have lost our minds) cannot ever explain the terror. My doctor didn't know what was wrong with me?! -My boyfriend (at whom I had just screamed "get out -I need you to leave now!" -because I wanted to hurt anything that moved) had to run and get another doctor while this one stood and stared in shock as I ripped out my IV, screaming "What is Happeining to me!" I wanted to kill myself. I was making a beeline for the outdoors and I would have done it. The seeming choice: Death or be aware of my rapidly increasing and certain insanity. I am a soft-spoken, not particularly impulsive person. I still just can't believe I survived. I'm sorry that all of you are here with similar or equally scary experiences. | I've noticed a difference in these posts that those of us who recieved it through IV had loss of sanity where those who were given prescriptions experienced parkinson's-like symptoms. An absolutely unbelievable experience for all. | F | 30 | 1 times | 7/2/2007 | 1 | Nausea | Extreme restlessness, jittery, like I was jumping out of my skin. | Took the suppository and by the next day I felt out of control and couldn't sit still or calm down at all. Called my doctor concerned and all they said was "It's a normal side effect and should go away." By the next day, I had my husband take me to the emergency room where they gave me a shot of Benadryl to counteract the effects of the compazine. I will never take this medicine again. I would be too afraid of the serious side effects. | F | 36 | 2 days | 6/30/2007 | 1 | Nausea/Vomting from stomach virus | Muscle twitching, my legs were jumping constantly, could not sleep or even lay still....Lasted about 4-6 hrs after taking only one pill...Tried this medication at 2 different times and it happened both times....Didnt even really help the nausea | Would not take this medication again due to this side effect...Was really annoying and drove me crazy! | F | 49 | 2 days | 6/17/2007 | 1 | food poisoning | I went into anephleptic shock after taking this medicine and almost died. My tongue swelled out of my mouth and I could not breathe and my blood pressure was so low that I was unable to walk or even sit up. DO NOT TAKE THIS MEDICATION! | F | 28 | 2 days | 5/11/2007 | 1 | Side effects of chemotherapy | Violent, shaking, Parkinson's like symptoms. Disorientation. | Doctor had to administer an anti-histamine drug to counteract Compazine. | M | 65 | 2 days | 5/4/2007 | 1 | combat nausea from pain meds | Extreme dry mouth and mild blurry vision. On the fourth day I experienced major muscle spasms in my face that resulted in a dislocated jaw. I was rushed to the emergency room, given a shot to stop the spasms and my jaw was then reset. It was quite painful. | M | 44 | 4 days | 3/2/2007 | 1 | nausea from migraines | I was taking compazine for the nausea from the migraines I was having on top of taking thorazine which was being tried to control my depression & extreme anxiety attacks I was having. All of a sudden, I wasn't able to walk without help & couldn't coordinate my hands to feed myself. I went to the ER at first & they suggested that the compazine might be the cause of the parkinson symptoms. I stopped the compazine immediately but the symptoms didn't go away. After a few weeks, I went to a neurologist & he realized that the thorazine also could cause the same symptoms. After then stopping the thorazine, it took almost a month more for the symptoms to finally go away. Both Compazine & thorazine can cause the parkinson symptoms which was why after stopping the compazine at first, the symptoms continued until the thorazine was stopped. | I was on the combination for around 6+ months before the parkinson symptoms showed up. The compazine worked well for the nausea but the side effect was so extreme that it was necessary to find another med that did the same thing with out the extreme reaction. | F | 46 | 6 months | 2/16/2007 | 1 | Uncontrollable vomiting | I got the drug through an IV since I couldn't keep anything down. I was released, but back in the ER only a few hours later. Felt like my skin was crawling off my body and I could not stop moving. I had this urge to walk and do yard work, trying to make it stop. Thought I was going crazy and went completely hysterical. Got some Benadryl back in the ER and was so thankful the doc knew what it was. SCARY STUFF!! | If you have a reaction, put it on your allergy list, and make sure you have some Benadryl around just in case. | F | 35 | 1 days | 2/11/2007 | 1 | nausea and vomiting | This was given to me through IV. I immediately started feeling utterly horrible. Some of the feelings are almost impossible to put into words. I was incredibly paranoid and thought the person giving the injection was trying to kill me, and I was angry. I wanted to kill him. I told him to STOP giving me the drug, and not to give me anything else. I repeated, "No more drugs!" But he ignored me, of course. I wanted to pull the IV out, and I wanted to stab the man with it. I also wanted to stab myself with it. I wanted to die. I felt completely detached from reality; I wasn't real, and neither was anyone or thing else. I started hearing voices, and everyone said there was no one there. The sensation was that I was a figment of imagination. I was utterly terrified, and went into a full-blown panic attack about the time they gave me something to knock me out completely. | I would not recommend this drug to anyone. It didn't even stop my nausea. I was still unable to eat for another day or two. It was almost a month since this drug was administered, and yet when I think about the feelings it induced, I start to panic all over again. This drug REALLY messed with my head, and I think it should be pulled from use. | F | 37 | 1 times | 1/25/2007 | 1 | migraine and nausea | I had it through an IV mixed with benadryl (which I now know is to counteract these side effects) while in the ER. My nausea did fade but I'm not sure if it was because the migraine was fading or because of the Compazine. The side effects though were not worth taking the drug. I immediately felt it going through my veins. I felt my body slow down and for a terrifying moment it got extremely hard to breathe. I felt as if I were suffocating from the inside out, as if the process of breathing in and out was shutting down. I know that I panicked some because I became afraid that I was going to die. The numbness focused on the left side of my body; it became difficult to lift my left arm up. My dad was talking to me, and I had great difficulty coming up with and voicing responses. I managed to roll onto my right side with difficulty still and dozed off so that I could escape the nasty numb feeling. At home, the numbness and feeling of not being able to sit still continued. I stayed asleep | Find something else for nausea, the akathesia is not worth it. | F | 18 | 1 times | 1/10/2007 | 1 | Control nausea after tonsillectomy | The most terrifying experience for me at 16 - I thought I becoming retarded. I first had difficulties talking. Then struggled to keep my tongue in my mouth. My jaw was misaligned. Probably other things going on, but I was most concerned with my face. The tonsillectomy doctor had told my mom this sometimes occurs in patience which don't use their jaw enough after surgery. Fortunately, my father came home from work and said we're going to the ER. ER doctor knew compazine was the culprit. Two shots of Benadryl did the trick. Jaw was very sore for about 3 days. | Wish the internet was around in 1988! Would have been great to access a site like this with great information. | F | 34 | 3 days | 1/9/2007 | 2 | Nausea from narcotic pain relievers | Uncontrollable restlessness and jerky body movements. | One of the worst and most terrifying experiences of my life. I could not stop moving my extremities, arms, legs, hands.Hands were shaking, could not grasp silverware, sign name, uncontrollable crying. Could not sit. Went to ER in ambulance, treated with utter disrespect at ER (I happen to be a nurse). I felt like I was truly going to die, in retrospect, I'm sure I suffered a panic attack in addition to the primary symptoms, but I will NEVER take COMPAZINE again, | F | 53 | 1 weeks | 12/29/2006 |