COMPAZINE Reviews (PROCHLORPERAZINE MALEATE)

Average Rating: 1.2 (501 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS VERTIGO MOTION SICKNESS VOMITING

 Type: Brand name discontinued; available as generic

  

COMPAZINE  (PROCHLORPERAZINE MALEATE):  This medication is used to treat severe nausea and vomiting from certain causes (for example, after surgery or cancer treatment). Prochlorperazine belongs to a class of drugs known as phenothiazines. This medication is not recommended for use in children younger than 2 years or in children going through surgery.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on COMPAZINE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR COMPAZINECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Headache from being struck I received this medication after not having anything to eat for more than 24 hours and I felt very nauseated as well as restless and jittery after receiving it. Then the roof of my mouth began to peel and now it burns when I eat or drink anything whether cold or hot spicy or not. I was given this medication along with Benadryl through an IV and would recommend that if offered, refuse this med. My headache came after a pint of paint fell and struck me in the head. F 49 1 days
1X day
10/10/2016
Email
 1  Headache Cocktail IV w/ benadryl SEVERE REACTION- sudden arm cramp/pain below IV site,spike of fever, agitation, anger, panic attack, EKG and BP changes The IV benadryl was given with IV Compazine to prevent any reaction. Did not work! M 16 1 days
Unknown
9/21/2016
 1  Headache Panic, scared and could not sit still. wanted to tear my IV out. Have never felt like this before. I kept asking to go home. It's been 48 hours and I am still jittery and my chest feels tight. This stuff needs to be banned! Benadryl did not help me. F 52 1 days
IV
9/13/2016
 1  Headaches Dizzy,restless, out of the world I got this as a migraine protocol and it messed with me so bad. I had to go back to the ER to get help this medicine will make you feel like you are dying it's is a horrible drug that makes one feel like you will have to move constantly and just cry bc there's nothing you can do to control it. M 18 2 days
10mg
9/12/2016
 1  Headache I was given this in the ER for a headache and within minutes of it given through my IV I felt like I was going crazy.. I was restless, kicking my legs, trying not to cry. I felt like I was going to explode through my skin. I felt extremely sick and jittery for 24 hours and now 3 days out I still can't eat anything and I feel so nauseous. Take this off the shelves I had sucidal thoughts and felt like dying was better then what I was feeling. I am terrified of this drug and hope no one else has to go through what I did. F 28 1 days
8/31/2016
 1  Headache Do not take this, HEART RACING, Sweaty, jittery, thought I was crawling out of my skin!!! My mouth would make funny twitches as well as body!! Thought I was crazy F 39 1 days
8/16/2016
Email
 1  Migraine Suicidal thought she leading to overdose on Tylenol, Advil and gravol My daughter spent 4 days under a form after attempting suicide after a migraine and compazine. We were never told of potential side effects! We almost lost our beautiful happy daughter to this drug! I am so happy to read these posts and Know we are not alone in ha in a severe reaction. F 18 1 days
1X day
8/16/2016
 1  Migraine I had panic attacks and heart palpitations. I was given this med for headaches. My heart rate shot up from 78 to 191. I thought i was having a heart attack. I could not yell out because i was too weak. So i started to pray. I felt stuck like it was never going to stop!!! The nurse had to give me adivan to calm me down. The nurse had to sit by my bed side to monitor my heart rate. It never went back to 78 it stayed in the 90's. This is the worst feeling ever id rather feel pain. Please take this med and get rid of it before it claims someones life. This happened 2 weeks ago and im still a nervous wreck! I feel better reading others experience and knowing im not the only one who has been through this! F 30 1 days
8/16/2016
Email
 1  Headache Anxiety restless nervous uncomfortable it was given through a IV F 31 1 days
Unsure
8/12/2016
 1  Migraine I was given this via IV and had the worst feeling I've ever experienced as a result. Almost immediately after given the IV, I felt extremely panicked. I felt like I couldn't breath (even though I could breath just fine). I also felt as though I could rip a car door off. I was given Benadryl to counteract the horrible side effects. F 29 1 days
7/21/2016
 1  Migraine I felt crazy. I felt like I needed to get out as soon as possible. I felt as if I made some terrible mistake. My heart was racing and I felt so jittery This medicine needs to be taken off the shelves. It should never be given to anyone. I have suffered through my migraines every day for three months because I refuse to take compazine again F 17 1 days
7/17/2016
 1  Nausea and vomiting Ten minutes after getting an IV dose of this med, I felt like I was going nuts. My skin was crawling, I had very bad panic, and I was close to pulling my IV out and leaving the ER. This was absolutely the WORST physical feeling I have ever had...mind you, I've given birth and had multiple surgeries. Stay away! The benefits of the anti nausea effect don't outweigh the chance that this feeling will happen to you. I felt like I was dying. F 29 1 days
6/30/2016
Email
 1  Neasea Well I was taking compazine because I kept vomitting after my wisdom teeth removal. Well turns out I'm in the 2% of people allergic to it. I had severe dystonia, my lip and jaw drooped, I looked like I was having a stroke. My teeth would not unclench and the worst was my neck muscles were out of control and I looked like I was the exorcist. Scariest experience of my life. I couldn't stop looking up. Thank god they gave me iv Benadryl and my neck finally went back to normal F 21 1 days
6/29/2016
 1  Nausea from stomach flu Jittery, anxious, angry, restless, muscle spasms, profuse sweating. I was given this garbage via IV for nausea in the emergency room due to me losing 10 pounds from vomiting/diarrhea from the stomach flu. After about 5 minutes I noticed that my legs wanted to kick and they began cramping. I started sweating and I wanted to start punching people and rip out my IV and start running as far away from the hospital as I can (even though I drove lol.) I started to calm down about 20 minutes later and when the nurse came back I asked her why I reacted like that and she said that it happens with some people. The doctor gave me a script of this crap (which I will never fill,) I'll just stick to Pepto Bismol. Avoid this medicine. Don't ever take this shit. Ever. M 32 1 times
6/19/2016
 1  As a part of migraine protocol Restlessness, muscle aches, extreme discomfort, the feeling of wanting to "crawl out of my skin". I received this drug as a part of migraine protocol IV cocktail (Benadryl/Compazine/Dexamethasone) in emergency room after experiencing 3-day long severe migraine bout. Immediately after the IV push I experienced the feeling of restlessness and muscle cramps similar in sensation to what happens during rising fever. It felt as if anything touching my skin was giving me the feeling of great discomfort and irritation (clothing, blanket). I realized that it might be a reaction to one of the medications in the cocktail but wanted to give them a chance to work anyway and did not alert the nurse. The cocktail worked in the sense that it broke my migraine but even 2 days later I'm still experiencing same side effects of restlessness and muscle cramps, although diminished. Just waiting for Compazine to leave my system at this point. F 43 1 days
10mg 1X day
6/3/2016
Email
 1  For a headache Anxious,dizzy,weird,uncomfortable. I had in as the ER through an IV if felt horrible still feeling it the next day. Worse drug ever F 27 1 days
5/31/2016
 1  Headache I was given this drug through an IV in the ER after complaining of a headache for three days. Within minutes of taking the IV I felt weird, dizzy, out of it. I went home and although my headache was gone I still felt dizzy and anxious. I had a panic attack and had to go back to the ER. They gave me an IV to try and flush my system. I went home. The next day I still felt dizzy and drowsy. I went to the doctor and they gave me a medicine to control the dizziness. They said the compazine would just have to run its course. This is day three and I'm still having trouble sleeping, dizziness, and anxious feelings. I'm hoping it wears off soon. I would not recommend anyone taking this drug!!!! Stay away from it!!! F 27 1 days
5/25/2016
Email
 1  Migraine Headache I became convinced that the ER staff was trying to kill me. I was completely out of my mind! I tried to use my phone to call my wife to tell her they were going to kill me but could not figure out how to use my iPhone. I got up and started ripping off leads and pulling out my IV. All I could manage to say over and over is "something is wrong!" When my wife got me home, I was terrified to go to sleep because I thought I would not wake up again. I presented to the ER with complaints of confusion and severe headaches after having suffered a concussion a couple months prior. M 36 1 days
10mg
5/8/2016
Email
 1  Nausea/high b.p. in E.R. Instant severe irritability, severe panic attack! literally felt like I was crawling out of my skin. They said some people get that reaction.It is not an allergy.Nobody told me this was an ati-psychotic they just happen to use for nausea geez. Was given Zofran and did fine. I will never let them inject another drug without looking up the drug. This is a well known side effect of Compazine. Terrible drug for nausea,might work well for a different use,as intended. M 52 1 days
40 1X day
5/3/2016
 1  Severe nausea While it helped the nausea a bit, I feel like I'm going to crawl out of my skin! I took a 10 mg. pill about 90 minutes ago. I feel jittery, anxious, and I want to cry. Never taking this medication again. F 36 1 days
10 mg
4/12/2016

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