COMPAZINE Reviews (PROCHLORPERAZINE MALEATE)Average Rating: 1.2 (501 Ratings)Filter ResultsCompare COMPAZINE with similar:
Type: Brand name discontinued; available as generic
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 |
More on COMPAZINE: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR COMPAZINE | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 4 | NAUSEA/VOMITTING | Slight drowsiness for about one hour after ingestion. | I was prescribed Compazine oral tablets - 10mg - due to nausea and vomitting related to an underlying illness - to be taken only as needed - sort of like on a "rescue" medication basis. Other anti-nausea medications had been tried but did not do the job. The Compozine worked wonderfully. The only side effect was that about 20 minutes after taking it, I would feel just a little drowsy for about an hour or so. After reading all the negative ratings here I have to wonder: #1 Is this one person with a grudge making multiple negative postings or #2 It seems that many of the negative side effects came after I.V. administration and not oral - could that be the difference? In any case, thank you (all)for your info - I shall be a bit more cautious with it and keep the Benadryl handy. | M | 56 | 8 weeks | 6/11/2009 | 2 | Migraine | Jittery, crawling out of my skin, ansy, anxious, I honestly thought I was losing my mind. | I took this drug for a migraine. They did not give me benadryl with it. I fought every urge to pull my IV out and take off running. I yelled at the nurses and went into a complete rage, which was nothing like the person I am. I couldnt get comfortable and i just wanted to crawl out of my skin. I couldnt talk, or even drive. It was absolutely horrible! I worked in the ER so I called a nurse I work with and she told me to take benadryl. I did and the symptoms got much much better. I had the jittery and uncomfortableness for a few days afterwards, but my migraine was gone! My recommendation- only use if you are given it with benadryl! It's a mistake to not be given both meds at the same time. | F | 26 | 1 days | 6/5/2009 | 1 | Chemotherapy premed | 5 minutes after receiving through an iv, felt antsy and could not stay still. I told the nurse and she said other patients had described the "hebby jebbies" from benedryl but not compazine. Within minutes things got much worse. I felt rage, anxiety, restlessness and thought "if this is the way it is going to be during chemo I would rather not live and be put to sleep". These feelings increased over the next two to three hours and I had no patience with people and did not want to talk to anyone. After about 7 hours I started to return normal, but did not fully recover until nine hours after treatment. | I am telling my oncologist to take me off the compazine and put in my records that I am allergic to this drug. I would rather have the nausea. I have advised everyone to skip this drug. It should not be given for nausea. Maybe only for mental illness. | F | 66 | 2 days | 5/23/2009 | 1 | Sick with stomach flu & nausea | Very restless - could not sleep because of horrible dreams - then my jaw locked up and my tongue was sticking out and my lips were curling - this was awful! We thought I was having a stroke so rushed to ER where dr calmly said "Oh yes - reaction to Compazine" - Gave me 2 pills of Benadryl and within 1 hr was back to normal. The whole incident was a nightmare! | Should be administered with Benadryl! Or not given at all - what an awful drug and horrible reaction just to calm down my nausea. | F | 59 | 3 days | 5/19/2009 | 1 | nausea | First it just started with being jittery, extremely anxious and feeling like I couldn't focus on anything for any length of time. Simultaneously, I was fatigued beyond belief. Then the rigidity of the jaw came - I began slurring my speech, clenching my jaw in an unusual grimace like fashion, and my arms became spastic. I would drool and my tongue swelled up. Definitely allergic and wish I had known ahead of time about these side effects. Instead, the benadryl remedy helped about a week into the symptoms. | Would've rather had the nausea than this experience | F | 26 | 7 days | 4/29/2009 | 1 | Ovarian Cyst Pain | panic, anxiety, depression, rapid heartbeat | Horrible experience with COMPAZINE. Was in the ER for a burst ovarian cyst. They gave me morphine for the pain and after a couple of hours, while waiting test results, they gave me this. I was not nauseous so it was probably preventative. Within 10-15 minutes of getting this drug, I started to get really anxious. I was taken for a diagnostic test and thought that I was maybe just feeling worried, but I could not get the feelings to subside. It got worse and worse and I had to sit up and then pace my room. Finally the nurse came in and I told her what was going on. She was great - she knew right away that it was the drug. They gave me a shot of another drug to counter it - not benadryl because I can't tolerate that. It worked and within 3-5 minutes I started to feel better. Horrible and I will never accept it again. I am sure to mention this to all of my doctors. | F | 38 | 1 days | 4/11/2009 | 1 | Nausea/Vomiting | First tablet of compazine did get rid of the nausea quickly, but left me unable to focus and extremely jittery. Following rx directions I took a second tab eight hours later and the side effects became MUCH worse...Rage, suicidal thoughts, inability to stop crying, inability to get comfortable no matter what I did, extreme jitteriness, pacing, feeling like I needed to get out of my skin...I truly thought I was going insane. Wish I had known about the benadryl antidote when this happened! Allergy to this med is incredibly horrible! | Patients need to be warned about possible side effects BEFORE taking this med and have benadryl on hand. | F | 21 | 1 days | 4/10/2009 | 1 | nausea/stomach pains | I only would not take compazine because I found out I was allergic to it only after I took it. It started with my eyes rolling in back of my head and I couldn't controll it. The paid was unlike anything I every felt in my eyeballs it was like someone was pulling my eyeballs back by my veins. Then when I got to the hospital after they admitted me into a room in the back my tongue started to swell and slowed my breathing. It was the scariest thing ever! I was only 16 then now I am 25 but everytime I go to the hospital I make sure they know that I am allergic to compazine, I really need to get a medical allert bracelet just in case! | F | 25 | 2 days | 3/30/2009 | 4 | nausea and vomiting | dry mouth, loss of sense of taste, impotence | taken to control symptoms of a viral infection | M | 37 | 4 days | 3/26/2009 | 1 | migraine | wanted to rip out my iv, very panicked/uncomfortable, I was in a daze for 3 full days afterwards, couldn't keep still or get comfortable, the most horrible experience of my life | please get all the facts before taking this med, i think it's dangerous | F | 35 | 1 days | 3/17/2009 | 1 | Loss of muscle control. Was not able to talk, walk, move. Felt like I was lost in my body. Started have seziure and almost died. | This is an awful drug. I was told to never take it. I was given Raglan in another drug. I felt like I was going crazy. My blood pressure elevated. My Dr's told me I had anxiety problems. I went to the hospital and they recognized I was having an allergic reaction to medication. Don't take any anti-nausea. They're dangerous. | 52 | 1 days | 3/9/2009 | 1 | Migraine | Severe agitation and panic attack-like symptoms, couldn't get into a comfortable position, started pacing the hospital room, had to constantly fight the urge to pull out the IV, suicidal thoughts | I would rather have the Migraine. This took several hours to finally wear off and the doctor at the hospital brushed me off when I mentioned how it was making me feel. It was the worst feeling in the world and would never take this drug again in a million years. | F | 35 | 1 times | 3/9/2009 | 5 | Migraine | None | I am an ER physician and have prescribed Benadryl and/or compazine IV for migraines for about 3 years. At least 80-90% of the patients I treat with this combination feel complete relief of their symptoms in 30 mins. or less. In all that time I have had a solitary patient complain of aggitation as a side effect! I also suffer from migraines myself. They became frequent enough to warrant daily preventative medication; however, if I experience a break-through headache, IV Bendaryl and Compazine always works for me. | F | 42 | 5 times | 3/2/2009 | 1 | Nausea and vomiting in pregnancy | First my jaw felt like it was out of alignment, then I realized that I could not open my jaw without force. It felt like all of my teeth would break. I had jitters from head to toe and extreme anxiety and panic. It was the most terrifying experience I've ever had. I thought I was going crazy. Unfortunately, I thought it was related to my chiropractic adjustment and did not go to the ER. Having done some research though, I realize that it was the Compazine and I should have had medical attention. Symptoms lasted for several hours. | I will never take this medication again. | F | 40 | 1 days | 2/23/2009 | 1 | headache,nausea,vomiting | panic attack, heart racing, jittering, spasms of the tongue,twitchin in the face, couldnt sit still, suicidal thoughts | I WOULD HAVE RATHER BEEN SICK THEN TO HAV HAD COMPAZINE | F | 22 | 1 days | 2/12/2009 | 1 | ACL Surgery | After tearing my ACL i had surgery and they gave me compazine for neausea. I stayed the night in the hospital and was fine. It wasnt until 24 hours later the reaction started. It started at my toes and went up my body. I had no control over my body and my eyes rolled back, fingers spread apart and i felt as if i was swallowing my tongue. If someone didnt know me it looked as if i was having a seizure. My parents were panicking. About 5 minutes later i couldnt move, talk or do anything. I had to be carried down the stairs and was rushed to the ER. Once i got there i was put into a wheel chair and the doctors at the hospital thought i was mentally ill. My parents literally had to scream to get their attention. About 10 minutes later they realized what was going on and gave me Benadryl through an IV. About 2 minutes later my whole body felt like it had 200lbs lifted off. They say having this sort of reaction and your muscles tensing up its like working out for 4 hours. It was the worst ex | DO NOT TAKE. Even if you have never had a reaction to a medication don't even try this one. | F | 23 | 2 days | 2/3/2009 | 1 | Severe Nausea | I was given Compazine in the ER for severe nausea from a recent viral infection. I took my two doses within 24 hours of receiving the prescription. About 6 hours after the second dose, my hands and face became numb and tingly. About an hour after that, my jaw locked up and I couldn't move my tongue. I thought I was having a stroke. My speech was slurred and my jaw clamped shut. I was given Benadryl through an IV and immediately I began to feel better. I was told to NEVER take Compazine again. This drug should be taken off the market. | F | 38 | 1 days | 1/20/2009 | 1 | headache | severe anxiety,tremors, suicidal, violent, ripped out my iv wanted to jump out a window, | i wouldnt advise nobody ever take this | M | 1 days | 1/15/2009 | 1 | headache | Within 5 minutes felt spacy, and 15 minutes later, was freezing cold, shivering. Felt like I had gone insane. Could not bear the feeling uncomfortableness no matter what I did. I was repetively having crazy thoughts,many panic attacks,heart racing,thought more than several times to end life would be better than what I was feeling, after IV saline was done I went home with mom driving. Continued to feel in this manner for over 10 hours. | I feel this drug is very dangerous. Could cause insanity, injuries or loss of life(s). to say the least in my opinion. came very very close to ending mine. | M | 33 | 1 days | 1/14/2009 | 1 | Anti naseau with pain meds | I thought I was the only one who had this experience with Compazine. I went to the ER for pain associated with kidney stones. They started an IV for pain relief and in conjunction gave me Compazine in case the pain meds gave me naseau. The side effect wasn't immediate, it took about 5 minutes to start feeling scared, heart started racing and felt like I was trapped in my own body. I couldn't relax no matter how hard I tried. I told the nurse who came to take me down to xray how I was feeling and told her there was no way I could get an xray now and she just looked at me like I was weird. She probably thought I was a junkie just looking for the pain meds. I laid in the ER room for hours before I could function enough to drive myself home. It was HORRIBLE! Then it happened again a couple years later after I had another bout with kidney stones. I was in recovery and freaked out-literally! I ripped my IV out, ripped off my oxygen they tried to give me, swore at the nurse and my mom, told t | F | 35 | 1 days | 1/6/2009 |