HUMIRA Reviews (ADALIMUMAB)

Average Rating: 3.1 (750 Ratings)

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 Type: Rx Drug

  

HUMIRA  (ADALIMUMAB):  Adalimumab is used to reduce pain and swelling due to certain types of arthritis (such as rheumatoid, psoriatic, juvenile idiopathic, ankylosing spondylitis). This medication is also used to treat certain skin disorders (such as plaque-type psoriasis, hidradenitis suppurativa). It works by blocking a protein (tumor necrosis factor or TNF) found in the body's immune system that causes joint swelling and damage in arthritis as well as red scaly patches in psoriasis. Adalimumab belongs to a class of drugs known as TNF blockers. By reducing joint swelling, this medication helps to reduce further joint damage and preserve joint function. Adalimumab is also used to treat certain bowel conditions (Crohn's disease, ulcerative colitis) and a certain eye disease (uveitis).    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR HUMIRACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Haradenitus Superlativa Did fine at first. Then one infection after another. Had to stop several times ,and restart. Noticed on restart started feeling depressed, mood swings. I was suspicious but wasn't sure until now. Took my last dose today. I'm done Can't stand the mood swings, and depression. Rather deal with the pain If you suffer from anxiety,and depression please let your doctor know. At first thought my medicine wasn't working. It can make you miserable. F 63 0 months
40mg 1X W
1/22/2021
 3  Crohn's Disease Injection site reactions (redness, slight itching) on starter doses (80mg). Then nothing, but levels were subtherapic, so they added Imuran and went to weekly injections. Levels rose after 5 months, so I'm off Imuran, but still inject Humira weekly. Was off it for 4 weeks for resection surgery, now back on it. Notice a lot of oral effects: sore palate, bleeding gums, sore throat. Also some pain in hip and pelvic bones. And most recently, persistent mild headache. Not sure about depression- hard to tell. I do take a very low dose of amitriptyline before bed. I do feel quite sad sometimes, but that's kinda par for the course for me. I don't know if the Humira is really helping, as my main issue with Crohn's has been an ileocecal stricture, which was just surgically removed. Having surveillance colonoscopy six months post-surgery and if inflammation is still evident, I will ask to switch biologics. Maybe Entyvio or similar... M 66 11 months
40mg 1X W
12/29/2020
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 3  Rheumatoid Arthritis After 3 months it has taken away most of my joint pain. But it has caused me shortness of breath and heart failure. I am seeing my doctor tomorrow. Will not take anymore of this drug. F 66 3 months
40 2X M
12/20/2020
 4  Psoriasis and Psoriatic arthritis R For all these years of taking Humira, I did not have any major problems aside from weakness. This year, 2020.. I started having palpitations (tachycardia like) symptoms... one to where I passed out due to very high rate. I ended up in the ER and they stated that it was only palpitations and they sent me home. After it started, I had daily palpitations to this day with chest pain, soreness, shortness of breath... occasional incidents to where I am back in the ER. They finally gave me beta blockers to take only as needed as my findings are unremarkable after sitting in the ER for a bit. I do not know where my heart problems started from, Humira did help me a lot and I discontinued it. I am afraid of developing more problems now. F 46 6 years
40mg 2X M
12/1/2020
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 1  Hidradenitis Suppurtiva I developed a kidney infection almost immediately after the loading dose and could barely walk for a week from the pain, a SEVERE and stubborn sinus infection that I am still taking a 3rd round of antibiotics for, sudden swelling of my face, lips, and, eyes several days post-injection, head to toe red pin point rash, rapid weight gain (most noticeably in my abdomen) and changes in body composition, persistent mental fog, extreme fatigue (in bed for days and days and still no rested feeling or energy), increased frequency/urge re: urination (esp. while sleeping), bruising easily (took several weeks to heal), depression, anxiety, one morning I woke up with patchy white facial hair including a mustache, general malaise, red eyes, chest pain, increased shortness of breath (I have asthma), and my body aches in ways I've yet to find the right words to describe, probably because I'm losing the ability to remember what words I know and how to use them. It's been 4 weeks off HUMIRA and it still seems as though my body is presenting me with new, alarming side effects every other day, which is a tragic improvement over all day, each day. The worst part was being treated for each issue/symptom individually by several Drs. in different facilities without the ability to tie all of these incidents together with HUMIRA-compromised mental faculties? Both my father and brother have had success with this drug, but I can't say that I'm not going to end up paying with my life, which I hardly recognize as mine, anymore. My prescribing physician (dermatologist) was super enthusiastic about suggesting this option for the single recurrent abscess that was active at the time, but I have no idea what it happening my body at this point, much less which specialist to bring it to for proper diagnosis and treatment. I do get a lot of phone calls from my assigned nurse, Lauren, who is not well versed on the "rare" side effects I am now living with. BIG 2020 ENERGY THIS STUFF IS. F 35 75 days
40mg 1X W
11/19/2020
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 1  Anklyosing spondylitis Headaches, aching in teeth, pain in left shoulder blade that radiates down left arm. Very nauseous for a while week after injection and super tired. Helped with joint stiffness but made muscle pains I never had before. Not worth it. F 43 4 months
40mg 2X M
11/19/2020
 5  RA and Bechet's I haven't had any side effects. I have tried several treatments for pain relief without success. About 2 months after I started taking Humira I started feeling relief. My pain level continues to decrease. I have been treated for depression for many years. This too has improved due to the decrease in my level of pain. F 61 7 months
40 mg 2X M
11/13/2020
 3  Crohn's Humira had helped significantly for the pain. But after 5 years being on it I've realized I've become depressed with severe mood swings. Never noticed it right away until I started hanging my friends and realizing something very wrong with how I am emotionally. As well as becoming tired on some days and full of energy on others. This medication reacts differently to different people. M 23 5 years
2X M
11/11/2020
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 1  RA & HidradenitisHS Switched to Humira after 6yrs on Remicade. The Remicade was increasing HS flares. Had some relief from the Humira at about 3-month point, then the HS flares increased again. always within 1 day of Humira injection. On both -mab biologic drugs I developed chronic fatigue, unpredictable moods, anxiety, depression, both insomnia and heavy sleep, and general sense of malaise and lethargy. Also during this time I was diagnosed with small fiber neuropathy. I have also developed serious food sensitivities and allergies that I did not have before taking the biologic drugs. The RA has progressed, though perhaps more slowly due to the drugs, but my quality of life has decreased significantly. I recently stopped taking Humira. I would NOT recommend any biologic drugs to anyone. Humira is not called a chemo drug, despite that being what it is. Targeting, killing and modifying cells in our bodies is the very way that it is designed to work. These biologic drugs wage chemo warfare in our bodies, and the side effects and issues these drugs cause is because our bodies are fighting to get rid of the invader, which is the drug itself. No drug will save your life because we are human. We are not meant to live forever. Stay away from the -mabs and all the other biologic drugs. Live every day of your life like it is your last. F 47 7 months
40mg 4X M
11/5/2020
 1  Crohns Both legs from hips to ankles absolutely total agony. Called doctor and was told not a side effect. It blatantly says on humira site serious side effect. I don't have a sit down job. On my feet 12 - 15 hours day, 2 shots this much pain. Not worth it. STAY AWAY FROM HUMIRA M 42 7 days
160 1X day
10/22/2020
 3  Crohns M 64 2 months
40mg 2X M
10/18/2020
 3  Crohns Seems to be working for my crohns but I feel depressed to the point that I can't get motivated to do anything. Always tired because my mind is always racing and I can't sleep. Going to talk to my doctor this week week to see about another course of action. My quality of life has deteriorated and I don't want to live like this. It's not for me. It may work but has too many side effects. M 64 2 months
40mg 2X M
10/18/2020
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 5  PSA Little bit of injection site irritation I am in love F 65 10 years
40mg 2X M
10/4/2020
 3  Crohns Mood swings, lack of motivation, lethargic, negative thoughts, rashes. Other than small spots here and there on my skin and a burning rash on my hands (that quickly subsided after given a prescribed ointment) I was doing fine with Humira until I tried to ween off of the prednisone. Then the Crohns started to flare so my doctor had me inject weekly instead of every two weeks. Within 3 weeks of me being on a weekly schedule, I started feeling sluggish and unmotivated. I felt like sleeping in my bed all day, but with the family life, this was not an option. I then started having negative racing thoughts and then a lack of appetite. It wasn't until I was having a casual convo with my cousin, who happens to be a nurse practioner, suggest that I may be depressed. I brought this up to my doctor when I realized that the symptoms didn't start until she upped the doseage. Unfortunately the doctor does not believe that there is any correlation. I almost cried when I saw this website because it made me feel human again, knowing that I am not the only one experiencing these symptoms while on Humira. F 38 4 months
40 mg 1X W
9/30/2020
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 1  Crohns Fatigue, confusion and memory issues, nausea, mood changes and depression, hair fall, weight gain, skin rashes and chronic infections constantly. I felt as though I wasn't me anymore. Worked very well at controlling colitis, but the side effects were not worth it. Would not recommend. F 47 6 months
9/27/2020
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 3  Ankylosing Spondylitis Up until this point, over a year later, I had no side effects! However, it has taken me 2 months to realize and admit to myself that I have been dealing with depression for at least 4 months. I hadn't truly realized it until 2 weeks ago. I have had so many terrible things happen in my life, but have dealt with them and came out strong and happy. This is different...until this point I thought I was just having trouble dealing with the idea of having this disease for the rest of my life. But there are so many ups and downs in random moments. Memories of everything terrible flooding back like I only stored them away just to deal with them all now. I feel so alone too, like I'm just a broken detail in everyone's life. I'm embarrassed and ashamed to be me, especially in front of those who know of my disease. The depression slowly arrived and now that I'm aware of it, I'm afraid to find out it will worsen. Humira has physically just about healed any aspects of pain in my body. I was couch bound before it, looked forward to my shots shortly after starting it, and now I have to set a reminder to take the shot because I'm virtually pain free! However, now I have to try figure out if my feelings of depression are from this medicine or from the natural anger of having to deal with this disease and questioning the kind of day I will have tomorrow...everyone, including my family depend on me and I just feel helpless and broken. I will find out what is causing this depression and fix it, but my physical life will be over if I have to stop humira. F 32 14 months
30 mg 2X M
9/17/2020
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 1  Rheumatoid Arthritis When I first started treatment I told my Dr I felt awful really bad swelling in legs and pain was so bad I needed wheelchair before that I could make it with a walker. He told its what you need to control your disease it takes a while before you will see improvement. Month after month I felt worse and worse developed real shortness of breath went to pulmonary and cardio Drs after one year and was floored to hear congestive heart failure and restrictive airway disease I am only 50 and could not believe what I was hearing had to go on oxygen. I also in that year had multiple infections lung sinus UTI cellitis derma cysts that got infected never had those before. The whole time my Rheumatologist was telling me you inflammation is down you need this medicine. I am here to tell you I got very minimal relief from my RA symptoms and instead got all these other things. After the Cardo appt I told the Rheumatologist enough no more shots unfortunately it take a good 10 weeks to clear your system so they say. Well it has been 5 months no shots yes my inflammation is up and I have R A pain but not that much more then when I was on shots AND I am no longer on oxygen my heart is healing numbers are good and the cardiologist said the good news is most of the damage can be reversed. No more infections swelling weight gain insomnia or anxiety that is great . My warning to all is Humira and all the biologic meds out there alter vital functions in the body and OFTEN they cause immense damage to Do not take biologics the human body was not meant to be manipulated like that . F 50 12 months
30 1X W
8/29/2020
 3  Ankolysing spondylitis migraine (has since improved, but not gone), hangover feeling for about 30 hrs post injection, depression and mood swings. I believe it helps control my appetite which is good because I need to lose 60 pounds. I do feel better than I did last month so I believe it is helping the pain and inflammation. I have more energy, however my mood changes make it wasteful energy. Terrified of cancer and worsening depression may need to switch but will give it another 2 months before deciding. F 35 1 months
40 2X M
8/7/2020
 3  PsA It seems like it is finally starting to work in general but just found out it is making me reject a dental implant, also my low back pain has gotten worse. First 5mo. I saw no difference but now it seems it finally starting to work and at the same time side effects kicks in! F 76 6 months
40 2X M
7/24/2020
 2  Trial Mood change I don't think this has worked for my crohns Because I was on on trial I did not pay for my weekly shots M 66 52 days
80mg 4X M
7/19/2020
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