DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Prevention of getting Knocked up First period after the shot was EXTREMELY heavy with horrible unbearable cramps and a huge chunk came out made me think it was a miscarriage, really bad burning and rash to the vagina, depression, extreme mood swings, 9 lb weight gain in 3 wks F 18 2 months
8/15/2009
 3  birth control a HUGE and i mean HUGE wad of blood & maybe vaginal discharge came out the 1st week of august i have been bleeding/spotting everyday since then and its now entering 2nd week of september. im pretty sure an abortion occured i think i was pregnant and my test came up negative at the obgyn before my shot and that wad was my kid. and im pretty sure i have vaginal dryness i have no weight gain or any of the other things mentioned, but reading all these things does scare me. i am debating on receiving another shot. F 18 1 times
9/7/2009
 3  Prevent Pregnancy Got my first shot in the beginning of January 2014 and ever since the end of January I've been bleeding every other week for the past 3 months. My bleeding would last a week at a time, not heavy though. I just got my 2nd shot March 25 2014 and hoping that my body will get used to this drug and my bleeding will stop. If it doesn't I am for sure switching to another birth control. F 18 3 months
1X AN
3/25/2014
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 3  Contraception i wish i read all the reviews on this page before i got it, a friend recommended it to me claiming it to be amazing. First 2 months we're fine, slight weight gain and a few extra spots, nothing too bad. However the 3rd month i bled off and on throughout, ruined my sex life completely, i found myself getting aggravated over the simplest things, constant headaches, unbearable bellyaches, it was horrible. i've recently been put on the pill and hopefully this all improves (i started it 2 days ago) i would not recommend the DEPO to anybody, messes with your body so much & now i'm told my fertility could take up to 18 months to return! Avoid it. F 18 3 months
1X AN
10/29/2013
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 3  Couldn't remember to take pill. I am currently on the shot. I am sexually active. I've been on the shot since April and all of a sudden I started having light spotting and very weird cravings! Is this normal? F 18 8 months
Unknown
12/10/2013
 3  I couldnt remember to take the pill Loss of sex drive and mood swings I got on the shot because I could't remember to take the pill everyday. I thought the only side effect was weight gain and bone loss (I take Vitamin C daily) I just realized the my sex drive is like gone. My boyfriend and I are struggling alot because of it. After reading all the other comments I am scared to get of the shot because of the seide effects that can occure. I wish I new before or I would have picked another method. Not having a period is great but not worth it. F 18 2 years
1/11/2010
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 3  Period and pregnancy With the shot i never had periods , but I always felt so weak and I would gain so much weight . When I decided to stop taking it because my doctor suggested I try something else I started getting feverish flashes, cramps that make me cry , it would make me nauseous where I couldn't eat , it was helping at first but after I couldn't get up in the mornings and I gained 50 pounds I wish I would've never started. Don't mess up your body F 18 3 years
2/18/2017
 2  Prevent pregnancy & control period Weight gain, mood swings, more hungry/increased appetite, fatigue, laziness, depression I absolutely love the fact that on depo I don't have periods or when I do, they're very light. But the side effects are just not worth it. Thinking about switching to Nexplanon... F 18 8 months
5/13/2016
 2  prevent pregnancy anxiety, spottting/bleeding, depression i've been on depo for about 5 months and i've been bleeding non stop for 4 months. i was told that “it will go away soon” by my doctor 2 months ago but how soon? my anxiety is horrible to the point to where i cant control it unless i take medicine. i havent had sex since i started this shot. my depression has ran to the roof. i never felt like this until i started getting the shot. F 18 5 months
2X O
12/29/2020
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 2  prevent pregnancy and previous mc Backaches,pelvic pain loss of sex drive and.cramps out of hell ! this is my first and last shot and no one told me it messes with future fertility and pregnancies F 18 1 months
1
8/30/2014
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 2  birth control two periods a month for first three months,nausea,loss of appetite,dizziness,small seizures anyone heard of seizures with this medication? had a brief seizure while receiving 3rd shot,sent to hospital,doctors cant explain F 18 6 months
6/27/2009
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 2   no energy, tiredness, not hungry, more annoyed, excessive spotting. i have only been on depo for a month. i had a lot of pain in my arm and shoulder after i first took it. i went pretty much symptom free for the first 3 weeks. i noticed i was getting tired in the middle of the day and im sleeping more then 12 hours a night, but i still just want more sleep. i have no desire to eat at all. i am on a mood stabilizer for my bi-polar disorder so my mood does not go to extremes, but i am getting really annoyed with my friends, family, and my bf. i dont know if thats because of the shot or my lack of energy. i am constantly cramping up like i would on my worst of periods and i have been spotting for 8 days straight already. the spotting increases after sexual activity and it is really causing me problems in the bedroom. i got this shot to inhibit the chances of getting pregnant and the shot works in the aspect of which im too tired and spotting too much to really want to have sex... thanks depo provera!!! F 18 28 days
4/16/2009
 2  birth control CONSTANT BLEEDING, vaginal dryness, ZERO sex drive, vaginal stinging, rectal bleeding, depression, irritability i originally began taking the shot about 3 months ago. i was supposed to get my second dose about a week ago, but have decided to no longer subject myself to these hormones. at first i thought i might have been depressed because of my recent move to a college hours away from home, but now that i'm reading all of these similar experiences, i'm beginning to think it might be the shot, as it al began a few weeks after my injection. the constant bleeding has been the worst - i'm sick of constantly bleeding through tampons (the heaviness of bleeding is unpredictable). and then who wants to have sex with blood-stained underwear? my boyfriend is constantly worried he is hurting me when after sex there is blood evident. the dryness has also been a great obstacle, as my boyfriend is often convinced i'm just not turned on, (and honestly, a lot of times i'm not - hence the zero sex drive). the vaginal stinging is relatively new as i've only been experiencing it for the last couple of weeks, but i F 18 3 months
11/10/2008
 2  Birth control Depression, dizziness, anxiety (mostly mood side effects), cravings I personally don't think I'm one who can handle hormonal contraceptives. I tried the pill before this, and it messed me up emotionally. The break I took between the pill and this shot, I did pretty good. Now I'm back to crying at the stupidest things. It's like I'm on my period constantly, though fortunately I haven't experienced any spotting yet (though I'm only a couple of weeks into it). I'm currently taking antidepressants for obsessive-compulsive disorder and the side effects of this shot seem to be cancelling out the benefits of that medication. Ugh. I probably won't go back for another shot unless I see an improvement. And I don't think it's a good sign when you feel really dizzy and shaky only an hour after getting the shot. And I'm not one who minds shots. F 18 2 weeks
11/5/2007
 2  wanted no periods panic attacks, mood swings, increased impatience and anxiety and prone to violent hysteria, weight gain, hunger increase, worse periods and bad cramps for the first month and couple weeks i did not bleed, so i was happy bc i was warned that there would be spotting. Well, now i have my period with horrible cramps and intense bleeding, not to mention i'm always hungry and have definetly gained weight in like a month. not to mention the heightened anxiety, horrible panic attacks, increased depression and very violent mood swings. I do not reccomend this to anybody, yes i do know ppl who have had no side effects, but i must say they are probably very few in number and extremley lucky!! i don't think i plan on getting the next shot unless this period/bleeding stops F 18
5/4/2007
 2  birth control slight weight gain and irregular, long periods The first month was great then I got a almost 2 week long period that stopped and started. It finally went away for about 2 weeks but then I got it back and have had it now pretty much, with a few days break in between, for a month. Due for another shot this week, dunno if ill get it F 18 3 months
2/15/2005
 2  birth control n painful periods Hair lost, weight gain, increase appetiet, mood swings, fatigue..... I will not recommended to anyone. I have being taking it for 2 years n the first year was great. By the secound year I begun to notice hair lost, increse appetiet n milk comming out my brest. N lots more. I never stoped my period. My period was regular for 1 year but the secound i will last for 1 month. It is horrible. Right knw i am trying to loss the 20 lbs. I gain in 3 months n now im swiching to junel1-20 hopefully things get better. F 18 2 years
1X day
7/12/2011
 2  to prevent pregnancy and regulate periods headaches, fatigue, really bad mood swings, depression, partially anti-social, hard to get out of bed, hair dryness, hair loss(falling out when brushed or washed), loss of appetite, weight loss it has completely changed who i am!!!! F 18 7 months
1X M
4/24/2011
 2  Prevent pregnancy rarely feel the urge to want to have sex, my depression increased a lot, anxiety increased, got more anti-social, feel constant tiredness and lack of energy, moodiness, i have also noticed i have i get sick easier and my allergies raised up since i have been on this, awful stomach pains during sex, vagina dryness, noticed every since I've been on this i developed more mucus in my throat, my breathing got REALLY BAD. i can only breath like 70%, not a 100% and all this happened 2 weeks after getting the shot. DON'T GET IT. IT'S HELL. Definitely not worth all the side effects you get from this drug. I don't understand why doctors are giving this out, it's terrible. And i hear so many woman still getting pregnant from it. I don't trust it. F 18 2 months
1X day
5/5/2011
 2  Less Periods, Pregnancy Prevention Bleeding Constantly, Random Cramps, Pain In Joints For First Week. I have been on the depo for three months. For the first month I didn't have my period till it was supposed to come. When it did, I only had a regular flow for three hours and then it was light disgusting brown. Since then I have been on my period for 2 months. I wanted this to prevent periods and cramping, but all it does is haunt me with them! F 18 3 months
1X O
4/1/2011
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