DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  irregular/heavy, painful periods I LOVED Depo for about 3 years. No side effects, no period and no other problems. Then as I was washing my hair one day a huge amount of hair came out in my hand. I had a beautiful bald spot right in front. I did not take the shot anymore and I really do miss it, but I am NOT going to be bald. No weight gain until after I stopped taking the shot and now it's like I can't lose it. I wish I could know I could get the shot again and not lose my hair. I have been off of depo for about 1 1/2 years now and my hair is finally growing back. F 43 3 years
1/6/2009
 1  Birth Control No periods,Depression,Dryness,Crying for no reason,loss of libito, and this is my wife, Girls, I could go on for hours about this awful stuff, dont use it , Try something else, My wife has been off this for two years now, its GREAT, totally diffent person, The Depo should been banned. M 43 10 days
8/11/2008
 1  Birth control I had weight gain and severe mood swings. I had no sex drive at all and extreme dryness if I did try to have sex. I quit taking depo about 1 year ago and am finally beginning to be normal again. I managed to ruin my relationship with my boyfriend because of my lack of sex drive and my anger. Luckily he came back after I got off the depo. I wouldn't recommend this to anyone. F 43 5 years
6/8/2008
 1  For the Essure Procedure Heart Palpitations, lack of sex drive, depression, paranoia, headaches, dizziness. I have only had one Depo-Provera shot prior to to receiving the Essure procedure. I won't be getting another one. I will be detoxing my body with anything I can find as quickly as possible as soon as this procedure is over. I have been bleeding for 2 weeks so far with no signs of letting up. I spend nights alone in bed full of anxiety and panic unable to sleep. I have daily headaches. Before the shot, my sex drive was insatiable, now I could care less. I sincerely hope that it returns after I rinse this toxin from my body. Please consider researching all the effects of this method before choosing it. F 43 120 days
5/6/2009
Email
 1  Stop heavy periods One week after my first injection my headaches are unvearable , neck pain and my right eye hurts all the time. Mood swings are terrible! I will NEVER get another shot EVER! And wish I had come across this site 2 months ago! F 43 2 months
2/4/2017
 5  Stop having a baby None been on it for 16 years and feel brill Saved a fortune on tampons no weight gain only a little due to eating and drinking more as I enjoy my food these days having a lovely person to live with the last 16 years! Hence the Depo F 44 10 years
16
5/29/2016
 5  Pain management difficulty in loosing weight when i do gain it. I've been on the shots for 8 years. I would not give them up for anything! I have always had extreme menstral pain, then in 1998 diagnosed with Fibromyalgia. Not only has the shots eliminated my periods (god send)I don't have to deal with the excruciating pain of a period which was adding to the pain of the Firbomyalgia. My Fibro pain has decreased significately as well. I've rollercoastered with weight all my life, so it's just a little harder. For me IT'S WORTH IT! I have my tubes tied, I'm a single mom and grandma and yes I have absolutely no sex drive which for me works. It lets me focus on my kids. I'd rather be a little overweight and single than suffer all that pain again! F 44 8 years
5/22/2007
 5  avoid pregnancy A bit of weight gain - I think. I have always battled with my weight so I can't say for sure. Depo helped me a lot. No pregnancy, no problems, no loss of sex drive and no periods! I went off Depo because I choose a permanent form of BC. It has been ten months and still no period. Recently my breasts have been very tender - maybe my period is on its way back - :( F 44 5 times
11/28/2005
 5  Fibroids, heavy bleeding and BC Some bone desity problems after 12 years on depo shots. I broke my foot and decided to stop the depo shots for this reason only. I was very pleased with the medication. I am going back on the injections after nearly 2 years off the shots because I have experienced very severe migraines every month at the beginning of my period and heavy, prolonged bleeding. I was overweight to begin with and cannot blame my current weight on this drug. Also - I was depressed before starting this drug, and with the help of an excellent therapist I am much, much better. (The depression and the weight gain seem to run in my family, so I look there for the cause.) This medication is not for everyone, but for me it works well. My OB-GYN tells me that without depo, I may be facing a hysterectomy. The severe migraines are happening at the beginning of my cycle, which lasts for up to 3 weeks and are worse than any I experiened in my life. Depo seems to be the lesser of many evils. I will have to take calcium supplements, but many women do anyway. I have missed the convenience of having no periods. I plan to give it another try. F 44 12 years
12/29/2005
 5  turned 35 and smoked so dr recommended some weight gain, no periods i love the shot and will continue it F 44 9 years
4X O
4/4/2011
 4  Not Estrogen based The only side effect I had while on it, was mild irratating headaches that would last for days. My problems started when I stopped taking Depo. Excessive fatigue, Night sweats, thrist, Abdominal and Flank pain, rash on my legs, loss of appitite, nausea, breast tenderness. I had these for 5 months till I had my first period then it all stopped. During the time I was coming off Depo, I was thinking I had something seroiusly wrong with me (Cancer or Kidney Failure). Almost weekly Urgent Care visits for pain and sickness. I had Ultrasounds and Cat Scans. My Dr's were stumped. Even though Depo worked fine for me it's not worth the pain and suffering I went through to come off. Completely upset my family and work lives. F 44 1 years
1X O
5/9/2011
Email
 2  to prepare for Essure procedure constant spotting about three weeks after taking 1st shot I had used Depo Provera when I was in my early thrities with wonderful results. The one down side was when I stopped the shot, I had cramps so bad I ended up in the hospital. That should have been a sign however I am not interested in having more children and began the process for permanent birth control which involved using some type of hormonal assistance. I never remembered to take BC regularly so I figured the shot was a safe option. Wrong answer. I have been spotting everyday since October 29 that approximately 54 days just shy of two months. So I accomplished my goal permanent birth control because I am not comfortable having sex while I continue to "adjust". Hopefully my doctor and I can come up with a solution short of a hysterectomy to stop the spotting. F 44 80 days
12/19/2008
 2  Long Heavy Periods Few hours after I got the injection, I got a headache, had the headache for 8 days. My periods previously were 10 days, now they are 15 days. After the period flow stopped now I am having (more than) spotting every single day!!! Only positive is the PMS symtoms were less. I will not take another injection!!!! F 44 6 weeks
1X O
8/26/2014
 2  Birth control Weight gain, fatigue, lack of motivation, sore breasts, night terrors, night sweats, erratic periods I gained 17% of my body weight starting the 2nd week after my 2nd shot. I'm 3 weeks away from my 3rd shot (which I will not be getting) and praying I stop packing on the pounds! F 44 6 months
2X O
2/23/2021
Email
 2  Birth control Weight gain, fatigue, lack of motivation, sore breasts, night terrors, night sweats, erratic periods I gained 17% of my body weight starting the 2nd week after my 2nd shot. I'm 3 weeks away from my 3rd shot (which I will not be getting) and praying I stop packing on the pounds! F 44 6 months
2X O
2/23/2021
Email
 1  Birth control Bleeding non-stop. No sex life with this shot. F 44 15 days
1X day
11/13/2023
 1  To avoid hormonal migraines Gained 100 pounds. Extreme depression and all over pain. Every system in my body’ was screwed up. I became nonfunctional I wanted to die. That’s how bad it was. A went from doctor to doctor begging for help. Enough that I’m flagged in the system that I was doctor hopping. It ended my marriage, my dream job, and took away so many years & it still has its ugly hold on me 5 years later. I despise this medication F 44 5 years
2/18/2020
 1  menstrual cycle I take provera.I cant stay awake can't eat very moody. My doctor didnt tell me the side effects wow I can barely work F 44 10 weeks
6/11/2014
 1  heavy bleeding Severe nausea and vomiting, shakes, chills, panic attacks, sweating, elevated liver enzymes,rash and itchiness, dizziness, continued and prolonged bleeding I would never ever reccommend this drug to anyone. I have now talked to 6 people that have had similar or worse reactions than mine. How is this drug even legal? F 44 8 weeks
1X day
4/21/2014
Email
 1  Extremely Heavy Periods Made my depression worse; SUICIDAL; Anger; Back Pain; Heavy Bleeding; Excruciating menstrual cramps (like labor pains) I am sooo extremely angry that I let my doctors talk me into getting this crap! I really hate doctors anymore. I have a 25 year history of Major depression and it is ALL over my medical history, and I should have NEVER been prescribed this BS! I AM ANGRY! I have been suicidal for 2 months since getting this shot, and although I have had depression forever and have had suicidal thoughts over the years, NOTHING like this! Then I start researching because of this and because of the excruciating cramps, and both are side effects. I almost fell to the floor. Not to mention, the whole reason I was taking this is because of extremely heavy periods that sent me to the ER in Jan & Feb for blood transfusions! And now, I've been bleeding for 10 days straight (HEAVY)! What the hell was the point?! I mentioned to one of my Docs that I was suicidal and that it is a side effect of Depo, only to be told 'no, I don't think so!' These docs need to go back to school & get educated! DON'T TAKE THIS DRUG! F 44 2 months
1X O
5/3/2014
Email

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