DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Not to get preggo F 31
1X M
4/7/2013
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Patient History
 1  birth control I experienced an increase in appetite and started gaining weight after being on depo for 3 months or so. I have since stopped getting the shot, its been almost 3 months since I stopped. I gained a total of 15lbs, 5 lbs for each shot I received. My appetite has still not returned to normal. I am seeking ways to "detox" from depo. Get all the facts before going on this drug - or better yet stick with the pill. I wish I had. F 31 1 years
8/14/2006
 1  Birth control Bone loss and a tumor on my liver. Is their any lawyers out there, taking cases from patients that were on Depo-Provera for six years. Holla at me. F 31 6 days
9/22/2006
 1  Birth control I spotted for 2 months until 1 wk before thanksgiving. Then I bleed every other day. I gained a few pounds, no sex drive, vaginal dryness and had some strong cramps. On 9/13/19, the nurse gave me the 1st depo shot but she didn't said nothing about the side effects. On 12/29/19, I went to the ER and the doctor said Depo is making me bleed and it should stop within couple months. After that day, I bleed heavier everyday & I was getting tired of it. I went online to see reviews about this & I discover a remedy. I took 2 1300mg Evening Primrose oil capsule each day and on the 5th day my bleeding stop. The FDA should never approve this shot. I hope one day the FDA will take this off the market. No lady should suffer like after taking a medicine that should help them. F 31
1X O
2/6/2020
 1   Nasty nasty stuff. I wouldn't recommend to anyone and I will not be having it again. I had it 2 weeks ago. After a week as it kicked it my mood has been horrific since. I constantly feel angry and I am nasty which is not like me at all. I've shouted loudly at my son a few times then cried. Also my labido is now zero- no wonder it works because I don't even want sex. My relationship is suffering too, I keep arguing with my partner because my mood is so rubbish. Can't wait until this wear off, but I'm thinking my relationship will be over by then. Never again. F 31 3 months
3/10/2017
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 1  Contraceptive Extreme migraines for 2 to 3 days several times, cramping, breast tenderness, pain in leg for 2 days after shot and extreme teeth sensitivity for several days, extreme fatigue and sleepiness every day, decrease libido, dryiness and pain during intercourse, depression, nausea and feeling like pregnant several times... Can't recommend it. My first and last with lots of regrets! Horrible F 31 1 times
4/30/2016
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 1  I am Anxiety .... paranoid weak tired not me at all ! I took the Depo shot oct 13,2021 I was 4 weeks postpartum I was moody for thoes three weeks and then November 6 2021 anxiety hit me like a wall that morning and been struggling since then with daily anxiety and attacks I been put on a anxiety med to help ! My next shot is January 5 2021 and I will not be taking it ! I want this junk out of my system I don't feel me I am an out going lady and have 3 kids and I been struggling to leave my house due to the anxiety ! Please if you have common symptoms please reach out to me ! I'm on week 10 out of 12. F 31 90 days
1 1X M
12/24/2021
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 1  Contraception I Started this contraception after my fourth child.I would stay away from ever having it. Since I started using it I have felt Depressed, Angry over anything I feel exhausted and have never felt so emotional.My Relationship has suffered because of my outbursts,It has destroyed me mentally and made me struggle with everyday life. F 31 0 days
30mg 1X day
7/26/2021
 1  Gave Birth. Needed Birth Control Nauseated, Fatigue, Depression, Anxiety Through The Roof. Chest Pains, Body Aches, Neck Aches, Moody, Crying, Horrible Thoughts, Aggression.. Etc I was perfectly fine Before I got this birth control! This was a horrible decision.. I feel like I'm losing my mind. It's almost 4 months later. I really hope these side affects go away! I'll never get the shot again. F 31 3 months
5/24/2020
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 1  Endometriosis, and pregnancy Vagina dryness, painful intercourse, uterus lining shredded, 3 weeks of bleeding I started Depo-provera in September the 30th 2022 I was going fine until a month in and had my periods For 3 weeks straight and had a continuous pain then realize that I had this long thing that came out of my vagina...i thought I had a miscarriage but I didnt. while I was bleeding/period and it looked like a blood clot but it wasn't. it was my uterus lining that had been shredded and ever since then I have had a very dry vagina. I have had problems having intercourse with my partner as it's been really sore and tight when he inserts it. I have seen the doctor to get onto (ACI -JEL Balance) which lubricanted the inside of my vagina and put acidity back into it because every time I had intercourse with my partner, it would be very sore and cause me to bleed after sex.I would have have to wear a panty liner constantly because of the jelly that came out. I then had a reaction to the panty liners and had to stop wearing them. I had itchy vagina and still dryness. I will never take depo- provera again STAY AWAY FROM IT!!!! it has ruined my sex life and I just want everything to go back to normal again. I've seen a gynecologist and he has put me on the pill as the pill called (levlen) it has estrogen in it which my body was lacking because the dep-provera took that away from me. It is now 6th of Januray 2023 still experience vagina dryness and feeling like my vagina is being ripped open when my partner inserts it still. I am going to wait it out and see what happens. F 31 90 days
1 1X AN
1/5/2023
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 5  To prevent pregnacy Weight gain How long did it take for anyone to get their period after stopping the shot. Please e-mail me F 32 8 days
12/27/2006
 5  heavy periods and birth control Stomach pain not that bad and weight loss only a few pounds F 32 6 months
6/9/2012
 5  to prevent pregnancy very light spotting once or twice a month which only lasts for less than a hour no weight gain, no periods, no mood swings, my doctor only recommends me to take it for 2years because of the side effect of reducing bone denisty. I take calcium pills twice daily as a precaution, I am very pleased with Depo. F 32 5 months
12/6/2008
 5  severe anemia, heavy periods depression, severe mood swings, irregular bleeding, tissue charge MISINFORMED - SIDEEFFECTS UNBEARABLE I was given the shot because I have severe anemia and I was having heavy periods. MY DOCTOR TOLD ME THAT THE SHOT WOULD STOP MY PERIODS. I wasn't told about the side effects or about all the controversy surrounding the Depo. I have not stopped bleeding since I received the shot Jan.19 causing me to be extremely tired. I have severe mood swings along with being depressed. I lost my job because I couldn't focus and I am irritated all the time. This is a warning to anyone considering the Depo shot, read the warnings and side effects. I am amazed at the negative effects it has had. For some people, no side effects occured but for others, the side effects have greatly negatively impacted their lives. I'm not getting the second shot and I want to warn women thinking of the Depo to reconsider. Research all of the testimonies, warnings and side effects so you can make the decision that is right for you. I wish I had!!!!!! F 32 42 days
3/1/2007
 5  Can't take estrogen-based bc Acne, slight weight gain Not having periods is fantastic. Before taking Depo I had severe menstrual cramps, migraines and mood swings, and Depo solved all that. I gained 5-10 pounds after starting, but have been able to keep my weight steady since then. It does aggravate my acne slightly. Overall, it's been great. F 32 5 years
9/23/2004
 5  Birth control Some spotting during the first few months. I had ONE spot on my face where I would get an acne cyst about 2 weeks after the shot, which would eventually go away. Decreased sex drive, but not sure if that was due to the shot or my loser BF! Love it! After several months, stopped having periods. Shot is quick and easy and you don't have to worry about forgetting to take pills. I have taken pills before and they make me spot continuously. Depo caused some very minor spotting, which went away after a couple of cycles. I did not gain any weight. F 32 2 years
4/7/2009
 4  Birth control Decreased sex drive, headaches, hot flashes. During the first year, there was a lot of irregular bleeding, but it didn't bother me because it was much lighter than my regular periods used to be. All in all, I think Depo Provera has been great. And having no periods anymore is WONDERFUL. My biggest complaint would have to be the decreased sex drive. There have been a few times where I was a month or more overdue for my shot, and suddenly I desire my husband again. I also have much more sensation during intercourse during these times. Depo has made me feel asexual. I have no desire. F 32 10 years
9/21/2008
 4  Birth Control Low sex drive, moodiness,no periods, weigh gain, feeling hunger after having meal, craving for sugary foods Depo-Provera worked well as a birth control. I also loved not having menstrual cramps as well as periods monthly. The drug did lower my sex drive to the point where I was once very active to the point going months without wanting sex. I had been on the shot for 4 years. I recently stop taking the shot 10 months ago due to the weigh gain. I just started my cycles back but, now it appears that they are followed by sever head aches. I loved the security of the shot but, I am unsure about the long term side effects. F 32 4 days
10/15/2007
 4  keep from getting pregnant hot flashes/slight dizzy -unbalanced/ 15lb weight gain/ no sex drive/ tired/ bone density loss(dexa scan)confirmation its good for no pregnancy but I really wish there was no weight gain or bone loss issues because it's so easy to go every three months and not forget to take a pill everyday. I wish they could improve it. F 32 2 years
3/3/2008
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 4  I took Depo to stop sever Pain. Weight gain, Pain all over, Break out on my face (BAD) little to no sex drive, Food craving's, Mood swings, Depression, Pannic atacks, tired all the time. I started Depo after going to a OBGYN to find out why I was having so much pain every single month, I have 2 kids and I have been cut burned and tied. When they could find nothing wrong with me I went o my Fam. Dr and she said this would be great for me. (Yea Rite) She said a little weight gaine. (HA)Try 60 lbs in 11 months. Now I am coming off of it and OMG the crap I am going through, Pain in my stomach, Quezzy, Head aches, feel more moddy more now than ever, I worry about things more now than I ever did. It's not worth it. If I knew then what I know now I would have not took the first shot I would have took something for the pain. Do it ladies, Please F 32 11 months
7/15/2005
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