DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  contraception Backache, dizziness, feeling weak/fatigued, changes in mood, daily crying for little or no reason, mood swings, irritability, vaginal dryness. I've been on this for around 4 and a half months now, with the first injection I had mild side effects but didnt attribute them to the depo. After the 2nd one Ive not stopped crying. Other effects like dizziness and vaginal dryness also crept in, which I wasnt experiencing before, and the aches are continuing to get worse. It all makes me a nightmare to be around, particularly for my partner, which defeats the object entirely. My next injection is due in about 5 weeks, but I will not be taking this again and hope the effects wear off soon. F 22 4 months
2X AN
3/21/2011
 1  birth control massive period, tired, NO patience, horrible mood swings, out of control hormones, no sex drive, uncontrollable crying... This seemed to be the only option that was going to be convenient for my life with a newborn - not having to remember to take it... It was HORRIBLE. My period continued into 60 days... Spotting then stopping then a PERIOD. I would cry with my son because I was such a basketcase... It was horrible and I will not get my 2nd dose of this...EVER. I would rather try and remember to take the pill. HORRIBLE. But I have heard of some ppl that actually like this - not side effects like these... F 22 3 months
1X day
3/1/2011
 1  Birth control Depo has ruined my life. Within days of my second shot I started getting really bad dizzy spells. I noticed that I was getting headaches more often than normal and always feeling out of it. I'm up for my next shot this week ( which I will not be getting) and within the past week the anxiety has been horrible. It started with little attacks and now is a constant thing. Has this happened to anyone else?? I would never recommend this drug. F 22 6 months
1X O
1/23/2011
 1  birth control Bad constipation Nausea Unsettling stomch Upper right abdominal pain Dizzy Terrible frequent headaches Increased motion sickness Vomitting Weak Unintentional weight loss This birth control ruined my life. It made me feel symptoms of gallbladder problems. I had to get a hidascan, ct scan, endoscopy, several UAs and blood tests. Went to hospital many times. I even developed very noticable swelling in my upper right abdomen. F 22 2 years
1 shot 1X O
1/26/2011
Email
 1  Pregnancy prevention and no periods always hungry, stomach bloating, abnormal continuous period, alwats tired after getting my first shot, about 5 weeks later, I got my period. I still have it and it's been about 6 weeks now. I am always low on energy, I have to force myself to get out of bed, and do anything with my daughter. Coffee helps only for about an hour. I'm always thinking about eating something. This is rediculous. And low libido. F 22 90 days
1X day
8/16/2010
 1  prevention of pregnancy Irregular bleeding, moody, no sex drive, change in breathing My first dose of depo ends next week and I'm NOT getting another dose! I started the dose back in may and have been bleeding/spotting everyday ever since I got the shot. More moody and emotional over things that never used to bother me. Sex isn't the same i notice I'm not able to get or stay "self-lubricated" and can't enjoy it. over all I got the shot as a way to prevent pregnancy and its ruined my health and starting to take an toll on my relationship with my boyfriend and I. Overall I don't think anyone should take this F 22 1 times
? 1X O
8/20/2010
 1  Birth Control hair loss, extreme weight gain, depession, mood swings,sporatic periods that would last 1-3 months, severe acne,anxiety, loss of sex dive, pregnancy resulting in miscarriage. I DO NOT recommend this to my worst enemy! my hair was falling out in clumps, I was extremely depressed, and I had not an ounce of a sexual drive the entire time I was on the shot. The last straw was when I got pregnant on it and then had a miscarriage. Once that happened, i decided that it just wasn't worth it anymore if it wasn't even preventing pregnancy for me! F 22 12 months
1X O
7/17/2010
 1  Birth Control Extreme waight gain, deprestion, abdomanal pain This is the worst thing I have ever tried for birth conrtol. I have been taking it for about 18 mnths now and it was great for a while and for the past about 5 months I have been really irritable, sad, confused, and just crazy. You dont notice it but the people around you just tell you your crazy and dont like being around you anymore. You have no idea why you think you did nothing wrong, you thought everything was great but this depo shot makes a chemical embalace in your brain similar to bipolar or depretion. Please be very carful if you chose to take this. And please do not take it for a long period of time it will ruine you and the relationships around you. F 22 18 months
30 1X O
7/29/2010
 1  My sister was prescribed it Horrible anxiety! Moodiness, Even more irregular bleeding Hi, im a concerned, outraged brother that found this site after recieving no help from the "glorified, all-knowing Doctor." My sister started the shot due to heavy bleeding and irregularity. Her doctor put her Depo and after a few weeks of treatment she started showing signs of anxiety. So much so, she would regularly have panic attacks during class time. These attacks became so severe, her 4.0 gpa dropped to almost 2.0 because she couldnt sit through a single class. About a week after these side effects began, she saw her doctor again, but her doctor was clueless as to why she might be having these symptoms, and eagerly dismissed the idea that Depo could cause someone such harm. Really wish doctors were more concerned with helping people... M 22 3 months
1X O
6/23/2010
Email
 1  contraception mood swings, weight loss due to depression which led to early stages of anorexia, dizziness, nausea constantly tired, severe abdominal pains, bleeding DO NOT USE THE DEPO!!! (one injection once every 12 weeks) i went on the depo when i was 19 as it was far easier for me than taking a pill everyday, my local nurse recommended it saying it is one of the best forms of contraception. However now im 22 and have been off the depo for a year for a few reasons...6months into using the depo i started getting cramps and thought nothing of it then shortly after i started to feel slighty tired and light headed and quite emotional, after 12-18 months i started feeling extremely depressed and from there my side effects started, the final straw for me was after nearly 2 years i started to have light bleeding spells then when that stopped i have server abdominal pains to the point where i couldn't move. After serious discussion with my partner he agreed i should come off it clear my ststem of the drug and start planning a family. 6 months after i came off the depo my periods returned, irregular and after a year of no contraception we still have no baby and no sign of pregnancy so i started to do a bit of research... Doctors and nurses don't tell you how dangerous this drug is, it can make you infertile and can take anything from 6months to 2years for fertility to come back to normal, periods can take up to a year to return, your mental health can become effected -depression, emotion over drive hormones flying all over the place. I'll never ever go back on the depo and hope I've helped you make your decision. F 22 30 months
1X AN
6/28/2010
 1  couldn't remember to take the pill I had constant bleeding for 5 months, then my period went away (blood-wise anyway) I gained 23 pounds, had over 3 months of almost constant diarrhea and vomiting (while still gaining weight) riddle me that batman. my back constantly hurt, my arm and foot feel almost arthritic now, I was exhausted constantly, exercise caused too much body pain, constant cramping,and severe headaches. There is absolutely NO redeeming quality about this shot. DO NOT GET IT!!!! My doctor even told me that if my cycle didnt return within 10 months, that I would have to have hormone shots and that I may or may not be able to have children again. I am a single mom with 1 daughter. I am not looking to have kids now....but it is upsetting to think I may never be able to again. Do not get this shot. It is not worth the long term body problems you will have, possibly for the rest of your life. F 22 1 years
1/25/2010
 1  Birth Control, Period problems BITCHINESS, TIREDNESS, BLOATINESS, BLEEDING, PAIN WITH SEX, HUNGRY, WEIGHT GAIN ALMOST CAUSED ME CANCER ON MY UTERUS BECAUSE OF THIS HORRIBLE MEDICATION, THE WORST DAMN MEDICATION ON THE PLANET :'( IT BASICALLY RUINED MY BODY! DONT TAKE THIS. I GOT PREGNANT ON IT AND MISCARRIED I bled for a month before my actual needle was due, wondering why my bf pulled out and be blood every where after sex, painful sex like my innerds are being "RIPPED". Lots of problems, cramps, extremely bloatiness, back pain, loss of sex drive or overdrive of wanting it, hornmonal problems, unexpected bleeding, pregnant symptoms which I wasnt, ANTIBIOTICS CAUSES MAJOR PROBLEMS for your body, DISCHARGE AT IRREGULAR TIMES Mucus discharge that smell funny and dark in colour or clear from Vagina. I dont recommend ANYONE TAKING IT. CONSIDER YOURSELF WARNED!! F 22 2 years
30 1X AN
5/4/2010
 1   depression, anxiety, mood swings, tired all the time, and very emotional after i had my second child in 05 i started taking the shot and was terrified that if i got off i would become pregnant again so i took it for 2and a half years and i and no period and was very deperessed and i gained about 60 pounds over this time when ever i heard about the i.u.d. i got that done and 2 years later after having problems with that also i started taking the shot again and now i remeber why i stopped taking it in the first place! but i am terrified of getting pregnant again. and of course my husband doesnt understand why i have been so moody and sad lately. F 22 2 years
1X day
4/28/2010
 1  couldnt remember to take the pill depression, severe stomach aches, very frequent vomiting and diarrhea, numbness in hands, severe nerve damage causing severe arm, hand and wrist pain, massive weight gain(while throwing up and having diarrhea constantly, riddle me that batman) , sluggish, always tired, incapacitating headaches, moodiness, really bad paranoia, bone loss, easily broken bone, joint pain, thyroid condition............. I could not figure out how I had turned into this angry person who hated myself, and everyone else, I am still trying to battle the depression, I hate looking in the mirror, I cannot lose the weight, I hate being around people when I used to thrive around others. I am ridiculously paranoid about everything when I used to be care free. I am losing the ability to use my hands for more than 5 minutes, then they go numb, and once the feeling comes back there is enormous pain that goes from my shoulder to the tips of my fingers. I cannot grip things tightly at all, and cannot open jars etc. I have a hard time holding my 2 year old for more than a minute at best. I didnt get my shot last month and am trying to flush it out of my system, still havent gotten a period, but I guess that is normal till the 3rd month of not having the shot. I am just hoping that I can get treated for the damage it has caused me and I hope people do what I was too stupid to do, and actually read about what this thing can do to you before they get it. Its a poison in my mind, and I wish I had never taken it. I have such a mess to deal with, and I just hope that I can go back to the way I was, and like myself again once I get my body back....... F 22 592 days
1X AN
4/5/2010
 1  contraceptive NO SEX DRIVE WHAT SO EVER AND A WHOLE LOTTA WEIGHT GAIN! When I 1st started getting the shot due to pressure from my mother at the age of 18, I thought it was wonderful... no more painful cramping but best of all.... NO MORE PERIODS...which had been a serious pain in the ass cause i had had breakthrough bleeding for like 4 years at that point. I suffer from migrains since a young child and my pediatrician thought that i needed to have a period so i didnt get the shot that sept. my period came in jan and that same month i was pregnant. Fast foward to Sept of 04 i have my son and get depo b4 leaving hosipital. I'm 5'10 and weighed 132 b4 preg and got to 154 at end of preg. Weighed 138 after baby. Fast foward to May 07 and im a fat ass 170 pounds. 40 pounds in less than 3 years. But the major problem is that i dont have even a inkling of a sexdrive. Its completly gone and is a major problem between me and husband. I try to get him to understand that this shot is the root to a lot of my problem via the lack of sex the weight gain the crazy ass mood swings. NOBODY TOLD ME THIS SHIT WHEN T HEY STARTED STICKING ME 5 YEARS AGO. If it were not for the fact that i cant bear the thought of having a ccle or enduring the cramps i would get off of it. Im in a catch 22. damned if i do damned if i dont. F 22 5 days
5/16/2007
 1  BIRTH CONTROL COMPLETE LOSS OF LIBIDO!! weight gain. apprx 5lbs. mood swings. depression, headaches. BOO TO DEPO wow, i recently got off of taking depo. 2 months later, still feeling the effects, but getting better. i can't wait til i feel myself again! i couldn't figure out why i felt this way about sex, and then i started doing some online research and i found out that many women had these same side effects! vtw, it's made my relationship rocky but luckily my boyfriend is understanding...when i talked to my doctor about it, they said they had never heard of these kind of side effects (loss of interest in sex) they did say that women report having a dryer vagina because it lowers estrogen, and they recommended switching to an estrogen bc instead. i can't believe after reading all of these women's comments that no one is doing anything about it. wow. F 22 6 months
6/30/2007
 1  Heavy periods, bad cramping, Weight gain, headaches, lethargy, NON STOP BLEEDING The depo made me start bleeding three days after taking it, and now I have been bleeding heavy (some days very heavy - but never light) for 14 months now! I have been through three doctors, none of whom know what to do, and tell me to wait it out. WAIT IT OUT?! I have been waiting it out for 14 months...how long does a girl have to bleed for?! I am now anemic, and have been for a year, and I am taking all sorts of supplements. I can't deal with it anymore! F 22 9 months
5/3/2007
 1  For birth control, stop periods weight gain, hair growth, mood swings, ect Do not take depo provera it has caused major complications to my body. Please contact me for more info F 22 9 months
1/18/2005
 1  WORST SHOT IN THE WORLD mood swings, no sex drive, panic attacks, unbelievably long periods, irregular spotting and the worst DEPRESSION i think i will ever experience in my entire life. I've written on this comment board before. When i first realized all the syptoms i had were so unlike me and that they were due to the depo after only one shot....I told my doctors but no one would believe me...it was like i was a lunatic. So i decided to go on the pill to even me out and IT WORKED! Once i began a tri-phasic pill...mood was instantly better...then i noticed most of the side affects of the depo went away after a while. After 9 months I stopped the pill, figuring that maybe my body and hormones would think that I was pregnant for those 9 mths and go back to normal on their own, IT WORKED! My period, mental health, sex drive ..everything is great and my husband even says that everyday I seem more and more like the person I used to be before the depo. IF YOU ARE LOOKING FOR BIRTH CONTROL REMEMBER THAT YOUR BODY CAN EASILY GET VERY CONFUSED IF YOU GIVE YOURSELF SOMETHING SO STRONG. JUST STICK TO THE PILL AND/OR CONDOMS! I WOULD WANT ANYONE TO GO THROUGH WHAT I DID! F 22 1 times
10/12/2007
 1  avoiding pregnancy weight loss, severe stomach problems and heartburn, palpitations, loss of appetite, bone loss, anxiety. I got my first(and only)shot in July. Within the first month I began to have problems with my knees and hips. By the second month I had lost 5lbs, which isn't normal considering I only weighed 116lbs. Now its been almost a year and i've lost 5 more lbs and suffer from extreme indigestion and take lots of medications. I was a very healthy 21 yr. old when i got this shot and now I suffer from physical ailments of someone over 40. This shot is a quick fix, but its not worth it! F 22 3 months
5/25/2007

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