DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Birth Control None, but things changed.... I loved Depo! I had no period, no spotting, my insurance paid all but the copay and I didn't have to remember to take a pill everyday. Loved Depo and recommended it to friends! Until, all of a sudden, I started spotting VERY heavily and at very inconvenient times (i.e. a wedding). I struggled with it for about a year, and decided to switch to the pill. Things are normal now, but I'm sad that I had to switch. Wish I knew what happened. Has this happened to anyone else? F 25 7 years
1/18/2006
 3  Contraception No period, mood swings, hot flashes, intense anger, hair loss, forgetfullness, weight loss, sweating more than usual, easily irritated. I dont know if the good side effects are worth the bad ones. F 25 2 months
1X O
6/19/2012
 2  Birth Control, Dysmenorrhea, Acne Weight Gain, Hair Loss- over 2/3 of the hair on my head (made my mother gasp and cringe in fear when she saw me for the first time- that was singly one of the worst things to happen in my life), 50-60% of my pubic hair, thinning of the rest of my body hair. Severe chronic migraines (1-14 week) for over 6 months (spent a semester in a dark room in my bed). It did help- stopped my painful periods. Everything else was not worth what I had to go through to stop them though. Now it has been well over eight months and I haven't gotten another period. Could have masked early menopause. There is a reason we're meant to menstruate! Will never go back on depo again. F 25 4 years
6/19/2006
 2  Birth Control hair loss, joint pain, breast tenderness, moodiness The first time I took it I was on it for about a year. I didn't notice any side effects. My period stopped all together which was great and my moods seemed good most of the time. I stopped when I started getting extreme soreness in my breasts near my arm-pits. I stayed off it for about another year, during which time I felt like I was a crazy person. Extreme anxiety. I finally decided to go back on it about four months ago. I just decided tonight that I'm not going to get my next shot. I was running my hand through my hair and a chunk of hair came out. I've been noticing a lot of hair loss when combing my hair, but didn't put it together that it was the shot causing it. It's been going on for about 2-3 months now, since I started back on the shot. About two weeks ago I also started having pain in my right hip. I can't really explain the type of pain, but it's off and on and feels like it's in the joint. There are the good sides to the shot, but for me, I just don't think it is healthy and I would not recommend it. It seems there are more people having problems than not. I believe that those who are rating it a 5 are either not aware of what it's doing to them or they just haven't used it long enough to experience the effects. F 25 4 months
2/13/2005
 2  birth control acne I am 25 and have never had acne before but now have bad acne which is scarring my face. Went to my regular physician who told me that this was probably due to depo provera. In fact, she said that women who have been on depo provera for a while tend to develop acne. F 25 8 years
4/15/2007
 2  menstruation cycle control increased appetite, decreased sex drive, mood swings, depression, cramps, frequent spotting I was taking it because my periods were out of control but I'm going to try a different kind of birth control after this shot runs out. It took until the second 3 month cycle of depo for me to really see how horribly my body and mind are responding to this drug. I didn't gain any weight because I watch what I eat pretty closely, but I do feel hungry like ALL the time. It did help with my period, but the side effects are not worth it one bit. My mood and mental state are completely out of control and it's hurting my relationship with my long term boyfriend. F 25 4 months
1X O
2/23/2012
Email
 2  contraception post pregnancy Mood swings, unable to feel when full, massive weight gain. F 25 3 months
1/23/2014
 2   hot/cold flashes, anxiety, possible hair loss At first this seemed great, no pills, no ring, no condoms, sex whenever.. then the hot/cold flashes started.. completely ridiculous, the bf hated it because my temperature would change every 5 minutes, he couldn't even touch me, I was too hot, the people at work got pissed I constantly changed the thermostat, whatever, I could deal with that.. 2 months in.. I'm to the point where committing myself to an institution is not looking like a terrible idea, I feel psychotic all the time and it's really taking it's toll on my relationships. There is a constant feeling of hopelessness as well. I can only assume this is from the Depo.. I have 2 friends that are on it and they don't have these issues so I guess it works for some.. not me though. F 25 2 months
5/8/2008
 2  birth control Weight gain, headaches, cramping I would not recommend this form of birth control to anyone unless you had no other options. I have gained 20 lbs since on the shot. I also experienced the worse cramping I have ever had right before and after I was to receive the shot. Although I loved not receiving my period, I could not take the pain any longer. I switched to Mircette which is able to be taken continuously so that I do not receive my experience. However, since taking this, I have gained an additional 8 lbs with major mood swings. I have switched now to Levlite in hopes of less side effects. F 25 6 months
4/11/2005
 2  pregnancy prevention This shot makes you feel crazy. I was young when I started it so I just thought I was an emotional teenager. No, it made me nuts. Also it took 2 years for my period to come back because this shot eventually makes your period go away completely. I gained weight, had acne, depression. I finally got off of it and it took me a few months to feel normal again but eventually i did. The period was still missing for 2 years. Also, you have to go in every 3-4 months to get the shot from the doctor. Do yourself a favor and take a regular pill/ F 25 6 years
1X O
6/19/2021
 1  prevention I hve been on depo since Sept I got very very sick after taking this injection 💉. Had extreme headaches that caused papilladima and 6th nerve palsy. My Drs say its unlikely depo would cause this but I know I deteriorated straigt after taking this killer drug and they did mri scans and all sorts of tests but cannot find the cause.hospitalised for almost a month. I still experience a slight headach my skin went two colours. I regret the day I injected this because I'm still recovering from double vision. DO NOT USE THIS. I WISH THE NURSES WPULD ADVISE US BETTER I almost went blind because of this I would not advise anyone to use it. F 25 2 months
11/7/2016
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 1  wasnt tryna have another kid right Headace, high blood persure, no periods, also have be cramping, tiredness, weights gained, I wanna know how long side effect last if I had my last shot November 18 2015? F 25 3 months
4/23/2016
Email
 1  To prevent pregnancy Mood swings, headaches, lose of taste and appetite. I had been on depo before, my first shot was a success no problems whatsoever. It had been about 4 months after that I decided to try it once more. When I tell you it was the worst mistake I could of ever mad. I have been so moody my poor bf is tired of me I'm constantly lashing out at him accusing him of cheating and I can't stop I feel like it's made me crazy. Before the shot I was such a happy person so energetic now I hardly want to do anything, I guess different people have different side affects I don't have the same appetite as before I get sick of eating I take three bites and I can't taste the food after followed with nausea. Avoid this shot at all costs it's not worth it. F 25 1 months
1X O
8/28/2020
Email
 1  No pregnancy Hair loss Stroke Brain Bleeds No period Prolonged periods Hair loss Mood swings Inter Cranial Pressure Temp loss of eye sight And More My daughter died from these issues I'm fighting to get Depo off the market let's fight together. #JusticeForBre F 25 5 years
12/20/2019
Email
 1  birth control i took 3 shots of depro. and i was also taking haldol and prozac. i gained around 75lbs, so i would question drug interactions. i had not gained this weight until i took depro. i hated the wt gain, and i lost it all over a yr by starving myself and over exercising. this stuff is my nightmare. take the pill. i have been off depro for 5 yrs and i have not gained any wt back... thank God. F 25 9 months
4/11/2005
 1  Birth Control Weight gain, extremely DECREASED sex drive I would not recommend anyone getting on depo-provera. Once I got on depo-provera, my sex drive decreased tremendously. This has caused major problems in my marriage. I received my last shot in January 2005 and I don't plan on going back for another one. Hopefully I will get my normal sex drive back (I know my husband will be pleased). F 25 3 years
4/15/2005
 1  Birth Control Pain during intercourse, slight loss of libido My nurse, doctor and consultant were all surprised by this side effect, saying it was something they hadn't encountered before and initially tried to attribute it to lack of lubrication, although this was not the issue. Have also put a little weight on despite considerably improving diet and exercise regime. Having no periods was good, but lowering of mood, increase in sweating, body odour for the first time in my life was not worth it. Been off it for 6 months now and the primary symptom of pain during intercourse has not yet subsided. Hoping (really hoping!) it will go over the next 6-12 months. On a recent trip to the doctors I heard (with no names mentioned) another patient had had similar difficulties with her contraceptive that week - I was surprised as I had no idea these issues were so common, until reading this page. F 25 6 months
6/17/2007
 1  Birth Control 40 pound weight gain, type 2 diabetes, it completly screwed up my metabolism, painful sex, lack of sex drive, no lubrication, depression, joint pain I was on Depo from age 16-19. The first year and a half was fine, then i started getting majorly depressed and gained a ton of weight and sex was so painful. I went off of the drug because of all the side effects. A year later, I learned that I had aquired type 2 diabetes, and because of the severity and my age, I was immediatly put on insulin, which I will have to take for life. I've majorly changed my lifesytle and eating habits and have lost a ton of weight, but the effects of the Depo still haunt me to this day. This crap should be removed from the market, and it should not be given to teenage girls, as it will wreck your bones and metabolism. THIS DRUG WAS ORIGINALLY DEVELOPED FOR MALE SEX OFFENDERS AS CHEMICAL CASTRAITION! It's also been proven to cause diabetes in cats and dogs. Horrible stuff. F 25 3 years
2/16/2007
 1  Birth Control Constant bleeding, mood swings, painful sex, loss of libido Well, I guess it's effective as birth control...I can't have sex anymore! Either I'm bleeding (which has been going on for about 3 weeks straight, so far) or it hurts too bad. So, I won't be getting pregnant. Not only that, I am so emotional, and it's a big strain on my relationship with my boyfriend. This is a horrible drug. I got the last shot months ago, so I'm going to get on birth control pills to see if maybe that will help regulate my period. Does anyone know if it works like that? F 25 2 times
5/17/2007
Email
 1  to stop my periods i originally started the depo shot because i found out I had to have a cold knife conization on my uterus and my OB/GYN said i COULD NOT be on my monthly during it. GOSH, I would have rather taken the risk. Here I am, 6 months later, I haven't taken my shot since January and I now have no period (haven't had one since 10/06), I have pain after orgasm (when I actually want to have sex, which is never), my fiancee doesn't understand why he has to beg me to be intimate with him. Emotionally I want to but I'm scared of the pain. I had major depression and mood swings, also. F 25 6 months
7/9/2007
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