DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth control Spotting sometimes several times each month. Anxiety, paranoia, depression, and anger that seemed to come each month during PMS time. Would usually last about 2 weeks. No sex drive. Depo may work well for some people, my best friend loves it. It made me feel like I was going crazy. I have decided to quit taking it. F 31 1.5 years
2/24/2009
 1  birth control hot flashes, night sweats, anxiety, insomnia, infertility, nausea I didn't have any side effects on the medication, it was when I stopped taking it that the hell began. I had horrible anxiety, hot flashes, smells made me feel ill, and insomnia. It has been awful, the symptoms were worse when I first got off the medication. However, some of the symptoms have lasted for years. Not to mention the fact I have been unable to get pregnant since getting off the shot. But who knows if you can blame that on the birth control. I am SURE the other problems are due to the shot though. Oh, and I've lost bone density. It really is terrible. I wonder if my body has trouble getting rid of the fake hormones. Anyone else have an idea about this? F 31 4 years
1X O
10/11/2010
Email
 1  Birth Control I had Depo-Provera SubQ,which claims less weight gain.This version is injected into the muscle.I only had 1shot into my thigh muscle.My muscle has since degenerated.I now have a large dent the size of a 50cent piece in the front of my thigh,I am super petite,only weigh 110,no cellulite.The 1st few wks after injection I had nausea, migranes, vomiting every morning,decreased sex drive,body acne,severe mood swings.Into 2nd mnth all symptoms remained except the nausea. Due to losing my thigh muscle,giving me the appearance of visible cellulite on the front of my thigh I did not want to continue use.When I did not receive my 2nd shot my withdrawl symptoms were worse than the ones I felt when I started.My migranes moved to the back of my head and top of neck.I gained weight,increased 2pant sizes just to be able to zip up.I have severe bloating in lower abdomen, bubbling feels like kicking,acid reflux,frequent urination,excessive discharge, extreme fatigue,body acne, angry, impatient, increas I had Depo-Provera SubQ,which claims less weight gain.This version is injected into the muscle.I only had 1shot into my thigh muscle.My muscle has since degenerated.I now have a large dent the size of a 50cent piece in the front of my thigh,I am super petite,only weigh 110,no cellulite.The 1st few wks after injection I had nausea, migranes, vomiting every morning,decreased sex drive,body acne,severe mood swings.Into 2nd mnth all symptoms remained except the nausea. Due to losing my thigh muscle,giving me the appearance of visible cellulite on the front of my thigh I did not want to continue use.When I did not receive my 2nd shot my withdrawl symptoms were worse than the ones I felt when I started.My migranes moved to the back of my head and top of neck.I gained weight,increased 2pant sizes just to be able to zip up.I have severe bloating in lower abdomen, bubbling feels like kicking,acid reflux,frequent urination,excessive discharge, extreme fatigue,body acne, angry, impatient, increased anxiety (mood swings),sweating then overly cold,boobs are bigger and if you squeeze them they have fluid like I'm pregos.This is a horrible drug!The fact you cannot find the real side effects or real withdrawal symptom details,nor how long these symptoms last makes it very misleading.I haven't even found a blog which discusses Depo-SubQ.This drugs negatives greatly out weigh the positives, definitely choose another method for birth control. DO NOT TAKE THIS DRUG!!! F 31 3 months
1X AN
1/17/2011
 1  pre-essure tubal procedure required SEVERE post-pardum after 7th child triggered by shot. 25lb weight gain in 2months.insomnia, loss of libido, pelvic pain and bloating, feeling pregnant/tired, hungry, depressed, suicidal. I am now dependant on Zoloft to keep me even chemically. I was suicidal and unable to pray myself out, or go to counseling or anything I would normally do. I am also seeing a weightloss doctor to help. He was immediately concerned that I had taken depo. He is giving me b12 shots every 5 days to help balance me out. My poor husband is having to deal with my loss of interest from the shot and the Zoloft. I hope my system clears soon. I have heard it could take up to 9 months for one shot to clear your system. Please DO NOT TAKE THIS DRUG. F 31 1 times
1X O
5/21/2010
 1  birth control non -stop period for 5 months The first time i took depo everything went well,but this last time as been a nightmare. I took my last shot Jan. 2009. I had a period in March and April,spotted for one day in May and didn't have another period until October which was kind of normal. The next period came in Novemeber and it's still here. This is really runing my sex life. F 31 2 times
50mg 1X AN
2/25/2010
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 1  Birth Control Mood swings, depression, weight gain, muscle pains, migraines, altered thought process. I starting taking this as the pills make me very sick. I will never take this again. I have felt like a shell of my former self for the last three weeks. That is when the depression has been really bad. I have had thoughts of suicide... this is horrible. I am usually the most positive fun loving person who is really laid back. Not lately. F 31 3 months
1X O
3/23/2011
 1  contraception Its nice not to have to worry about a pill everyday I was on the shot the day after I had my son. I was on it for almost a year and a half. I gained almost 90 lbs while on it. The mood swings were horrible. I got off of it and my periods haven't been the same since. I am lucky if i get 2 a year. I wanted more kids and I don't see that happening. I am very disappointed in thsi drug. F 31 1 years
1X O
9/10/2011
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 1  Contraception I started depo in September 2009. I had gone into the doctors for a repeat of the pill and they recommended the injection (silly me for trusting them...lesson learnt never take any medication without thorough research!) At first I thought the drug was perfect for my first two shots at least. Then I began to notice mood changes I was experiencing bad mood swings, but more importantly I felt really angry and for no reason at all. I mentioned this when I went for the next injection and the nurse said 'no it can't be the depo' do I had the injection...and more after that as I had 7 injections in total - my last was January 30th 2011. At the this point in time i bad gained 16 lb in the time i had been taking the injection and my dress size had increased from a stable uk 10 since adulthood without ever dieting to a 14. It was only after the 7th injection that I began to research depo and realise that this was the reason I was feeling so awful, by this point I was very tired, suffering with headaches, my asthma had got worse and the mood swings were horrific. I also got kidney stones which were really painful and although my doc denies any link to the depo i think there is quite a logical one seeing as stones form from lack of calcium and depo causes osteoperosis as it reduces the amount of calcium in the bones. whilst on depo my periods stopped entirely I would only have spotting when wiping while on the injection. My poor boyfriend put up with a lot, but I am thankful to say F 31 9 times
1/12/2012
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 1  prevent pregnancy I am a total nutjob. I wanted to have another child and didn't want to go back on the iud. So I opted for depo. I have back pain to the point that I can barely move and it's not just related to motion. I can be dead asleep and wake up with such a spasm and shooting pain it takes my breath away. I hate everyone and on the verge of a divorce because I am so angry all the time. I am not a violent person but now I find myself wanting to smash things, yelling and screaming all the time. Having fits of rage that actually scare me. Not to mention the depression. It's the worst, I don't want anything to do with anyone I cry for no reason nothing makes me happy and when I do become happy I cry even more because I feel so guilty for being so angry all the time and that puts me back into another depressive fit. I was diagnosed with uterine fibroids which the doc is pretty sure that I am seeing due to the shot. I feel totally out of control and am miserable. I got the 3 month shot and am 7 weeks i It may seem like a great thing but really check into this. I am scared what the residual side effects may be for me. And how long it will take to get out of my system, also not to mention the fibroids I now have because of taking it and if they will go away or get worse. I can't believe this is still on the market. F 31 7 weeks
? 1X O
2/6/2012
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 1  birth control After I was done taking depo I had a sudden weight gain I can not lose. I have had alot of female problems,and problems with my blood sugar. I know all of this is from Depo-Provera. It also makes it difficult to get pregnant when you finally decide to. I would not take this if I were you. I use to be very thin and healthy. Now I feel like I'm 60+ years old,and I'm only 31. F 31 2 days
7/5/2005
 1  Birth control Bone loss and a tumor on my liver. Is their any lawyers out there, taking cases from patients that were on Depo-Provera for six years. Holla at me. F 31 6 days
9/22/2006
 1  Birth control rapid weight gain (5 lbs. on average each time I got the shot), loss of sex drive, migraines, mild depression F 31 5 years
7/19/2006
 1  no other form of contraceptive suit backache muscle pains neckpain moodiness loss of sex drive headaches nausea inability to sleep depression i would never go near this drug again F 31 3 months
9/28/2004
 1  Birth control Gained 30lbs in three months, cystic acne on face, back, chest, severe depression, no sex drive, hair growth on chin, PCOD, no period for a year after only one shot I think they should ban this drug. I know some people love it, but it has ruined three years of my life. I am just now getting over some of the side effects. I will sadly always have the PCOD now though. F 31 90 days
10/6/2008
Email
 1  07-07-2012 Just had my baby 18 days ago and this period just won't stop. My husband is a very hard worker and I hate him so much everything he does makes me upset. When we were pregnant we were like to love bird's and now its like STOP TALKING TO ME STOP KISSING ME. I'M UGLY I'M FAT AND YOUR LIEING TO ME JUST TO MAKE ME FEEL BETTER ABOUT MYSELF. F 31 3 months
30
7/24/2012
 1  birth control,endometriosis After taking this for over a year I started having horrible pain all over my body. Have bone spurs in my hands and feet. Possibly have arthritis and celiac. The doctors are pretty sure its the shot causing it. I know some people do well on it but please if you start experiencing anything odd stop using it please! These symptoms don't just go away you are stuck with them forever F 31 1 years
7/7/2013
 1  For contraception after child no Weight gain I was pregnant when my dr gave this needle to me and he didn't test me before and I miss carriage six years I have had trouble of no periods and mood swings crying nausea vision problem I now have premenopausal problems and I have had scans for piturity tumor as all my hormones are out I have seen 3 gynos so far and an endo and I'm with an amazing Natral path to get thing right I'm also getting checked for autoimmune diseases as that's what the doctors are thinking but all this can't be reversed if only I had known what this drug was going to do to me x F 31 1 days
30mg
5/20/2012
 1  Prevent pregnancy When I was on this shot i suffered from horrible side effects such as HOT FLASHES, NIGHT SWEATS, weird cyst like rash on my butt cheek, vagina dryness, no period, CONSTIPATION, BLOATING, SWEATING IN GENERAL, CHEST PAINS, FAST HEART BEAT, NAUSEA, ANXIETY, NERVOUSNESS, NOT ABLE TO SLEEP, no sex drive, DRY SKIN, NO APPETITE CUS OF THE NAUSEA, AND THE LIST GOES ON... I have been off this shot for 2 months May 3rd 2013 was the last day to get this shot and i said not anymore... TILL this day i still get nausea, still no period, fatigue during the day, mild cramps, still no sex drive, i lose my appetite on days i am nauseated, vagina dryness, a weird discharge, oily oily skin, nausea, acid reflex, diarrhea, pimples that hurt, mood swings, and still my sleep patterns are alil rough at bed time. The only symptoms that have left was hot flashes and night sweats. LADIES, PLEASE DO NOT GET THIS SHOT!! THE SIDE EFFECTS ARE HORRIBLE! I learned a lesson. The depo shot ruined me! If you ladies need t F 31 9 months
3 shots 3X AN
7/19/2013
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 1  Prevent pregnancy I had 3 shots... Chest pains, anxiety, nausea, headaches, aches and pains, dry mouth, always thirsty, sensitive to smells, weak, cravings for junk food, bloated, constipated, hot flashes, nights sweats (between my legs), sweaty hands, sweaty underarms, body odor, lost of appetite, not able to sleep, discharge, dark urine, and last but not least fast heart beats which scared me a lot! i wish I could sue! They do not list all the side effects of this shot. When you do complain about a side effect that is not listed they make it seem as if something else is wrong with you. They tell you, "Well, your body should be use to this shot, or get another one and the side effects will leave." Don't listen to them (Nurses or doctors). If you know you never experience anything that you have been going through on the shot before you got it, then it is 100% chance the shot is causing everything. I would recommend this shot to my dog. F 31 11 months
1X AN
4/22/2013
Email
 1  Afte having 3 child Chest pains difficulty breathing pain during sex weight gain acne back and stomach pain depression severe panic attack and horrendous anxiety. F 31 1 years
9/7/2012
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