DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  To regulate a cyst on my ovaries First month no bleeding. Second I bleed for 16 days. Here it is month 3 and I'm 20 days and counting. I get the constant migraines and terrible cramps which are a million times worst than I've ever experienced. I'm constantly releasing blood clots. I have back pains and Lack of sleep. The list goes on and on. I wouldn't recommend it to anyone. F 29 3 months
30 MG
2/24/2016
 1  Endo Relief/Contraceptive Minor weight gain 10-15 lbs, if I remember correctly 1 period after starting depo lasted a few days more than normal and some spotting maybe once or twice in the first year, mood swings I started when I was 16 or 17 as a means to cure painful periods and as a contraceptive. Besides minor changes, it was great, I rarely had cramps and very rarely were they super painful like before. Never had periods, but I did notice a little bloating or mood swings once in awhile, nothing concerning. I loved it and raved about it even knowing others had horror stories from taking it. I knew it worked for me. I once got off of it 4 years ago but only for maybe 6 months and got right back on it, maybe had 2 periods. In January of this year 2022 I was due and decided not to continue and to plan on trying to conceive in the future. The first few months were ok, started having periods, first couple lasted 2 weeks more or less, spotting, very painful, 6 months in, my breasts would get extremely sore and bigger, extreme bloating, took several pregnancy tests. My sex drive I started to notice would fade in and out causing serious problems in my relationship, it was so non existent that when it would come back only then I'd realize how much it comes and goes. I'm extremely irritable off and on, extremely depressed off and on, here we are almost 11 months of discontinuing depo and I am seeing doctors, had my hormone levels checked and they said they were fine. I have sought out counseling. I get extremely emotional and anxiety that makes my heart flutter, panic attacks, lower back aches/cramps, light headed quite frequently, my appetite is next to nothing, I force myself to atleast eat dinner. I am struggling to find answers and a cure to just be normal again. I do have periods every month, this time it has been 5 weeks since the last. If you asked me a year ago I would have highly recommended this, if you ask me now I would do anything for people to have facts and do any research you can. These long term side effects, the random restlessness, the irritability, the mood swings, the stressing over nothing, the depression and anxiety and the effect it puts on your daily life, is NOT worth it. I would give anything to find help right now and how to move forward. I take vitamins, b12, omega, have resorted to cbd for my anxiety, but of dozens of doctors throughout the years none have never told me any one of these things would happen. Look the other way. Depo is not the answer. It is miserable and scary. Reading these threads is all I can do to know that I am not alone. So if your reading this and have similar side effects please reach out, and if your reading this in interest of taking it and made it this far, look at the best interests of your future health, mentally and physically, I beg you. F 29 12 years
1X O
10/27/2022
Email
 1  Heavy bleeding I received depo in June 2021 and started to spot in July and it went on heavy bleeding since constantly everyday. Body ache and bleeding is issue. I didn't go for second shot which was in September please anyone tell me why I am still bleeding after stopping depo.its post 2 months since I stopped depo is this the side effects? Will it wear off and when please help. I wouldn't recommend anyone to take depo. It's devil shot. F 29 3 months
150ml 1X O
11/28/2021
 5  No pregnancy or periods Hair loss and muscle pain weight goes up n down F 30 9 years
4/25/2017
 5  Painful periods, Dr. reccommended 10 lbs gained initially, then lost them!! Price has increased to $200 per injection. Thank you Depo! My cycle had made me sick for my entire life, and after my doc started me on it, life for me began!! No PMS, no more acne, sex is great, and I feel great! My doc explained this drug is not reccomended for teens due to the drastic hormone shifts that occur during that time of life, and that bone density issues can be combatted with weight training and good nutrition. My thyroid and bone density tests have been perfect! I'll take this drug for as long as I can! F 30 8 years
7/24/2005
 5  Prevent pregnancy no period, possible vaginal dryness (this may not be from the shot) I love depo, it eliminates the risk of my forgetting to take a pill , and I love not having a period. Everyone's different, and reacts to drugs in different ways. If it's not right for you, don't take it. I hear an aspirin, held between the knees, works wonders. :D F 30 2 years
8/23/2006
 5  Birth Control Sex drive is sometimes INCREASED, no menstrual cycle (very happy about that) (Other = Year / 2nd time on Depo, on it 2 years so far this time The first time I went on Depo it was pretty much so I wouldn't have to remember a pill every day. I also liked the idea of a non-estrogen birth control option. The best part, NO PERIOD! If you're not trying to make a baby, why have a cycle? It's not medically necessary. I then went off for 2 years. I did take quite a while for my period to return to normal, but that's just my body. It's different for each woman. On my 28th birthday, I gave myself the gift of going back on Depo. Again, no cycle. Also, I'm actually allergic to latex (yea, always the alternate condoms for me). Seeing that I have a long term, faithful boyfriend and we're free and clear, we don't need them. The most important reason is that having a baby now would not be safe due to the medications I'm on (risks of developmental problems, etc). I've had no bone density problems, no ovary problems, nothing. The only issues have been a couple times when I get a shot from a generic batch and my body doesn't really like the inactive ingredient mix. I spot. It happens. Of the 7 total years it's happened 3, possibly 4 times. Small price to pay. I love Depo. :) F 30 2 years
4X O
3/28/2012
Email
 5  birth control I love the shot. No weight gain. Besides the year I was off of it to have my child I have been on this for 8 years. Normal bone scans. No issues. F 30 8 years
10/28/2012
 5  Aniemia a wierd feeling under my sternum. I have had some spotting and am always tired. i get very hungry every once and a while. i just started the depo shot. I have however used a generic one in the past and it works just as well. For my aniemia this is the best thing to use. F 30 14 days
1X O
1/4/2011
 5  to gain weight but it didn't help None. It is the best thing ever made. No periods in 11 years, not even spotting. No pregnacies. Will never get off because I don't want anymore children. I have a 12 year old and that's all I need. F 30 11 years
1X O
1/27/2011
 5  birth control my period stopped. other than that, i never gained a pound from it, i still eat, i'm not mooody, i'm very happy with it. i would reccommend it... i think its amazing. F 30 6 years
1X AN
10/26/2010
 5  birth control I have not had any side effects. Absolutely love the depo shot been on it for almost 2 years now. It's great not having a period every month and for me it has relieved me of the horrible monthly cramps on got with the pill. I tell all my friends about it who complain about their monthly problems and a few have also gone on it. BOTH of my friends who went off the shot to have kids were able to have kids with in a couple months!!! F 30 2 years
1/24/2008
Email
 5  B/C & No kids Before DP, I was already irregular. After depo, no period like many others. Had migranes which I thought were due to stress. All over body aches which I thought were from lack of exercise&stress. Lower back pains thought to be from epideral. Increased sex drive, increased appetite/sugar cravings. Before depo, 120llbs. Now, 9 years later, 160llbs; thought this was due to having 2 kids and not exercising. People say your body changes every 5 years. Now, I am 30. I have loved Depo up until this year. Now, around the "time of the month", I have been experiencing severe depression and acne I just can not get rid of. I have been on calcium, women's 1 a day, and green tea pills (curbs appetite and sugar cravings, increased energy with natural caffine), blueberry (antioxidant which helps with depression)protein shakes, high-protein diet, exercise, and I have lost 7 lbs in 1 month. I thought losing weight on Depo was impossible! Herbalist recommended SAM-E for depression. I am working on the acne cure still. Depo is not for everyone and after visiting this website, thinking about a bone density test. F 30 9 years
7/2/2007
 5  Birth control I have been on Depo for about 12 years. At first I had no sex drive. But after the first year, it returned. I have no periods. I lost about 30 lbs. when I started Depo. I hear all kinds of horror stories but have experienced none. Depo is not for every woman but it is for me. F 30 12 years
3/30/2007
Email
 5  menstrual migraines, bc hair loss, weight gain I was on depo for 6 years, I went on it because a dr. suggested it to help with my monthly migraines. I averaged 3 or so a month. Once on it I dropped to around 3 a year. Since I had menstrual migraines I was told that pills would more then likely make them worse because of the hormone fluctuation. I stopped depo in May of 2006 because my husband and I started thinking about wanting kids. By August I started to spot and by November I had started having a regular cycle. I didn't really have to many side effects while on the shot except the weight gain (45lbs in 6 years) and hair loss. My migraines have returned but usually only get one about a week before I start my period. F 30 6 years
5/30/2007
Email
 5  birth control Possible weight gain, but weight has been an issue for me my entire life, so I can't easily blame it on the depo. Low- to non-existant sex drive. This is the best birth control I've tried so far--except the lack of sex drive...which is an ironic twist, since I started taking Depo because we were having sex all the time! F 30 5 years
4/4/2004
 5  Uncontrolled bleeding No menstrual cycle, EVER! Irritability, dryness, stopped the shot to explore other options though I was reluctant because I love it. 5 years is a lot for the shot I guess.... Now that I am being weaned off the shot I am extremely crazy horny all the time! 30 5 years
9/24/2013
 5  Endo I absolutely love depo. I have a child and don't plan on having more so it's depo until menopause. No side effects or weight gain. Got migraines the first year but they evened out and were still better than the cramps I had before. If you gain weight and can't lose it on this find something new but don't let the small chance scare you away. This is miles better than the pill,implant,or iud. I've had them all. F 30 8 years
3/25/2014
 5  Because I hate my period No periods for a year. I get a depo shot once per year and it stops my period for the full year. Once my doctor convinced me to get it every 3 months- big mistake, I ended up with spotting and anxiety attacks. I went back to once a year and it works fine to prevent my period (yes, I know that this may not work as birth control). I had been having incredibly heavy and painful periods, to the point where I couldn't concentrate at work on those days. I was also having anxiety, depression, and sleeping difficulties before each period. Depo stops all of it (as long as I only take it once a year). F 30 4 times
1X O
8/8/2015
 4  birth control stopped my period. I took it for 3 years went off it for 5years and am about to go back on it. In the three years it was wonderful not to have a period (especially as I worked as a canoe guide and was camping for 5 months straight). I;ve always been moody and this drug regulated my moods so instead of being depressed spontaneously I was only depressed when the shot was running out and about 2 weeks before I got the next one. I may have gained a little weight but nothing drastic. And now that I'm in a relationship again I'm going back on it this week F 30 3 years
7/28/2009

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