DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  birth control Crippling Migraines,muscle tension neck and shouldrs. Migraines stopped after coming off but then the rest started. Drug should be banned, irresponsible drug company in my opinion. Not enough known about serious side effects. I thought at first it was a wonder drug(what women does want a period?), but eventually i started to drawn my own conclusions about the serious effects i was noticing on my body. Doctors will tell you nothing about long term and may misdiagnose side effects of this drug.This drug does not have adequate labelling. Before starting i had very normal periods and a pregnancy. After coming off after 7yrs i bled non-stop for 7mnths and now have cysts on my ovaries and no period, possibly Polystic ovarian syndrome. I completely blame depo for the problems i'm now facing, and wonder after 3 yrs of being off it if by body will be able to get back to normal. There should be a class action case against the drug company for not making women aware of the serious long term affects of this drug which have never been stated. F 27 7 years
12/22/2004
 1  cannot use oral contraceptives acne, mood swings, extreme weight gain, joint pain, headaches, lethargy i have gained fourty pounds and cannot loose it, at times i feel like i'd rather just die than face another day, i have severe acne on my face, neck, chest and back, my metabolism went from high with a regular digestion to being very low and now i go once every three to four days. i'm tired all the time, i don't even remember what it is like to have energy. when i talk to doctors or anyone about this they do not take me seriously. i am refusing to continue these injections and advise anyone who wants to be taken with more than a grain of salt about thier medical problems to stay away from this drug. F 27 2 years
4/8/2007
 1  Contraception Side effects: - Ruined Metabolism - Weight gain, 25kg - Thinner Hair - Beard growth - Abnormal Period for nearly five years - Change of emotions - Depressions I would never ever tell anyone to use depo provera, I met a woman today (by coinsidance) who has the same problems now as I had then... she gained 15kilos in a year! Sorry for my bad english I'm swiss... F 27 1.5 years
4/28/2006
 1  birth control decreased sex drive, non-stop heavy bleeding, excessive weight loss, hair loss, photo sinsativity- causing small blisters on my skin exposed to the sun, hair groth on chest, pannic attacks, and probably more that i was unaware of due to more severe side effects! I TOOK DEPO TO PREVENT GETTING PREGNANT A SECOND TIME. I WAS ONLY 17 AN HAD NO IDEA OF CHECKING SOMETHING OUT AND I TRUSTED MY DOCTOR. I HAVE TYPE ONE DIABETIES AND HAVE BEEN INSULIN DEPENDANT SCINCE 15. I BECAME PR EGNANT AND THEN HAD MY SON. MY DOCTOR INSTISTED I TAKE DEPO AND (NOT HAVE ANY MORE KIDS) DUE TO THIS AND OTHER HEALTTH PROBLEMS. SO I DID. WITHIN THREE DAYS I COULDN'T EVEN GO OUTSIDE IN THE SUN BECAUSE EVERY TIME I DID I GOT BLISTERS. MY HAIR BEGAN TO FALL OUT SO FAST I STARTED TO GET BALD SPOTS. MY DOCTOR TOLD ME THAT IT WAS HORMONAL AND THAT I NEEDED TO GIVE IT TIME. I WAS SOAKING ABOUT A PAD EVERY 2 TO 2& 1/2 HOURS. ONE THING IS FOR SURE IT WORKED FOR BIRTHCONTROL! THERE WAS SO MUCH BLOOD I WOULDN'T EVEN THINK ABOUT SEX. I STILL HAVE SCARS ON MY SKIN FROM THE BLISTERS TEN YEARS LATER. THIS WAS A VERY DANGEROUS AND TERRIBLE EXPERENCE FOR ME. I TRUSTED MY DOC AND I SHOULD HAVE RESEARCHED IT MYSELF FIRST! IF I WOULD HAVE KNOWN ABOUT HALF OF THE SIDEEFFECTS I WOULDN'T F 27 3 months
11/15/2006
 1  Contraceptive Where do you start! Anxiety attacks, headaches, dizziness, sweating, chest /upper back pain, difficulty breathing,exhaustion, a few hot flashes, lathargy, constant bleeding. Need I go on! I was on Depo for about 3 years and never had a problem with it. I stopped it for about 2 years to have my 2nd child and went back on it in January. I had no side effects after the first shot, but a few days after the 2nd shot, I started to have panic attacks, dizzy spells, sweating. I have been having the various symptoms off and on for the past 3 months and have got so bad that I am afraid to go out on my own. I find it very hard even to get up in the morning and if I didn't have kids I probably wouldn't. I have been to see various doctors regularly over this time and not one of them suggested that it could be the Depo making me like this-I found it out for myself! Due to get the injection next week but can safely say I'll be giving it a miss! I have been through hell over the last 3 months but hopefully will get back to my normal self and get on with my life again once the Depo has gotten out of my system. I don't know why it has effected me like this now but it has so beware t F 27 5 years
7/17/2006
 1  i was advised to i had the injection in jan i ve since had heavy bleeding bt now it has turned 2 spottin daily,this kills ma self esteem n i regret eva gettin into this awful medication. F 27 3 months
2/19/2013
 1  because I forget to take pills I have not had any bleeding or spotting, which I think is very abnormal for a woman.I I've gained 35 pounds with only one shot, I got the shot in November and haven't had a menstrual since. No sexual drive at all, bad mood swings, depression, loss of self esteem since I'm fat now. I can't wait until this poison leave my body, never again. F 27 3 months
2/17/2013
 1  prevent pregnancy weight gain, PAINFUL intercourse, low sex drive, anxiety, mood swings, non-stop periods after stopping and trying to get pregnant. Depo provera should be taken off the market. I haven't been able to have pain-free sex in a year, and I'm a newly-wed!! I avoid sex at all costs, how aweful!! It completely takes away all estrogen and you begin to have menopausal symptoms. I stopped taking it in October, it's almost July and I'm still having a ton of problems! I have continuous periods with a lot of cramping. I pray for all this to end!! Please don't ever take this drug or you will regret it!! F 27 3 years
6/17/2006
 1  birth control having had only two shots it has completley screwed me up i had them over a year and a half ago and now unable to concieve (been trying a year)it also caused my hair to fall out leaving me with bald patches and terrible mood swings F 27 6 months
9/10/2006
 1  Contraceptive aching bones, long period, headaches, deppression and bad acne I've only been on Depo-provera for 1 month, i have a calcium deficiency in my bones. It was only after having the shot that i started to experience extremely bad pains in my legs, then I started to get migranes and bad acne. I started to research depo-provera to find out what the side effects were and found out that my doctor failed to inform me that the drug should not be used by people who suffer from a calcium deficiency,as it may cos even more of a deficiency. I went to see the doctor today and he told me I have to live with it, buy some pimple cream for my acne & do happy things to make myself happier. i'm saddened that such a drug has been marketed and that doctors are promoting its use and not informing their patients. I hope I can make it thru the remaining 2 months. F 27 4 weeks
8/28/2006
 1  birth control Im actually posting for my girlfriend, she had her first shot just over a month ago, things seemed normal, then she got her period which the Dr told her she wouldnt even get anymore, now its been over 2 weeks and it hasnt stopped. So she saw a Dr today about it, he told her to "deal with it" (his exact words). Now after some research I see all this. Wtf hasnt this been banned, its ruining my GF's life, she's depressed, moody. This drug should be banned. Dont let anyone you know even consider taking it! very effective as birth control though, because you wont get to have sex again. F 27 35 days
8/28/2006
 1  dont want anymore children have3! Started off with mood swings, spots, lack of sex drive! After.2nd shot teeth ache severe hip pain and itching in breast for days but under the skin! Still have 6 weeks left on this horrible drug and god knows how long until i feel normal, feel like an oap! Do not get this. F 27 3 times
6/30/2013
 1  Prevent Pregnancy Spotting, Depression, Mood Swings, Extreme Anger, Suicidal thoughts. Sadness, Crying and emotional. Last night I got so upset with my boyfriend...I have never felt that kind of anger ever! Stayed up all night thinking what the heck is wrong with me...then it hit me. It's this damn shot!!! I'm normally a girl who can control my emotions, let things go. But lately I've been getting extremely angry, feeling sad for no reason and I never put the math together. I just recently got my 2nd shot and the thought that this will be in my body for another 3 months worries me. DO NOT take this shot. Try every other option before going on Depo. Like someone said its better to have a baby, than to be having suicidal thoughts and depressed. F 27 4 months
1X O
1/3/2013
 1  To prevent pregnancy Anxiety, hair thinning, panic attacks, depression, fatigue, emotional all the time, trouble switching off, bad skin.. the list goes on Do not take this form of contraception!!! Awful as so many others have already said. I hope I don’t feel like this forever as I had my last shot back in May and I feel worse than ever now I’ve come off it! Its affected my work and relationship! It did the job but really not worth it for the side affects. I will not be using any hormonal forms of contraception again, it’s put me off it completely and I don’t agree with it! I’m sure it works for some but I can quite clearly see here from the other reviews it’s definitely more negative! F 27 8 months
11/7/2019
 1  Contraceptive Lost my appetite completly Running tummy Bleeding does not want to stop Vagina burning Lost weight fast due to no appetite Do not use this! F 27 1 months
2 month in 1X day
11/14/2020
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 1  Pregnancy prevention Depression, anxiety, on/off brown discharge, hormonal, no sex drive, vaginal dryness. This was my second time on the depo (first time was a positive experience but I was a lot younger). This time I can only describe my experience as horrific. I became irrational, depressed, hated sex and the thought of it. Went to my doctor and explained my symptoms and she believed it was the depo creating these problems and 2 months off it I feel as if I'm getting back to my normal self. F 27 6 months
9/24/2016
 1  Birth control method Hot flashes,cold chills, headaches, anxiety, panic attacks, and nervousness. I do not recommend this to anyone because of the side effects that I've had taking this. I've had only one shot and I am due for my next shot but I am not going to get the next dose. It has caused me to have severe anxiety and I've had a total of 7 panic attacks in 2 months and 4 weeks time. F 27 1 times
8/25/2016
 1  Menstrual cycle Headaches, nausea, anxiety, severe bleeding with large clots This is absolutely awful. I've been to the er and I'm currently taking iron infusions because I've lost so much blood due to bleeding from this injection and I'm currently on hormones to stop the bleeding. I don't recommend this shot to anyone. It needs to be taken off of the market! F 27 6 months
4/21/2016
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 1  Pregnancy prevention Horrible Headaches,mood swings,severe anxiety, depression, no sex drive I was on the shot when I was a teenager with little to no side effects. I have since then had to children and decided I was sick of the iud since I have had it for five years+ I got the shot in December 2015 and it is now only January I have had extreme bouts of anger and anxiety hot flashes and a headache for a whole month! This drugs is horrible and my list goes on and on F 27 3 months
1/2/2016
 1  Pregnancy prevention Depo is my greatest regret in life. I have been off it since November 2022 and I thought I would feel better by now (February 2023). But I don't. I have crippling depression. I feel like all the estrogen in my body is depleted and it will never come back. I don't feel beautiful. I feel like I have lost all facial fat. All the feminine features in my face have melted off while I was on depo and I am afraid my face will not be full again. If you are having this symptom please let me know because I feel like I am the only one with sunken eyes and exhaustion! It is depressing and I never smile anymore. I feel like I have no more happiness in life … F 27 1 days
4X AN
2/11/2023
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