DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Birth Control - No Periods-Endometr NO SIDE EFFECTS AT ALL- THIS IS A GREAT DRUG. For everyone who is rating this drug terrible, it is important to understand that it doesn't work the same for everyone. Try it and if it doesn't work, quit taking it. This drug has been a life saver for me. I had horrible periods and awful cramping for years. When I started this drug, my periods stopped along with all the cramping. I've been on it six years now, and only recently have had my endometriosis symptons reoccur. I have not experienced any bone loss from the drug. The important thing to remember when starting this drug is to increase your calcium intake and exercise regularly to offset the bone loss issue. I will be switching to Lupron temporarily while being treated for endometriosis, but will definitely be going back on Depo as soon as treatment is finished even though I am having my tubes tied. I will take Depo as long as I can find a doctor that will allow me to stay on it. F 29 6 years
3/5/2006
 5  cramping, heavy periods, bc slight weight gain The negative side effects were indistinguishable, and it ended my monthly torture sessions. I had no problem getting pregnant with my first child after using it for 6 years, but my periods became terribly prolonged after my second stoppage. I look forward to going back to it. F 29 7.5 years
5/4/2006
 4  Combination Pill Nothing for many years apart from slight weight gain which I expected to gain as I got older anyway. Weight easy to loose though. I have been using the Depo for nearly 13 years now with really no side effects. In fact it was such a relief to finally get rid of my 3 week long peiords. However, having read some other reviews I am questionning whether the way I feel, i.e. sometimes very tired and moody is down to the injection? Loss of sex drive is a major factor but more recently I have expereinced very sore and swollen breats and abdomen. Having just got married and thinking of the future I feel now is the time to come off depo.....and welcome home the periods again....! F 29 12 years
7/10/2006
Email
 4  After my 3rd child Well I love depo... Been on it 7 years now 1998 till now 2005 I really like it... No periods since 1998 I am 29 years old and want to come off it. I have things wrong with me,just devolped High blood pressure a yr ago,my body aches everyday,I did loose some hair cant tell tho,Im moody and always tired,I have 3 kids and lost my son in Jan 2005 My stress cant be blamed cause of depo but the point is I want to come off it and very scacred? I have an appt# with a obgyn just as a precaution for me with my son I bleed in my sleep at 35 weeks and that has put the bleeding to death fear into me,if I know I wouldnt die I wouldnt go back to get my shot,Im healthy otherwise but want off it,I want my period back~ as stupid as it sounds I dont want to be 35 and still on depo,to me thats silly I simply didnt want to get pregant again after my son in 1998 we both almost died and I wanted to stop myself from having any more children,but now I want off~ please email me about how it affected you AFTER you took your last shot?please [email protected] SHerry some side effects could be do to depo: hair loss,headahces,yes acne,bones hurting,high blood pressure,fat belly~bloating M 29 7 years
7/28/2005
 4  prevent pregnancy spotting off and on, anger It's been a month and so far it's been ok, i just started spotting last week. I haven't had a period since my baby was born (5 months ago) so this might just be my first one. Problem is it's been over a week. As for the anger issues, it could just be being frustrated sometimes. But i don't recall ever being that angry. Other than that it's been great so far. I'm not pregnant so it's doing it's job. Also i've still been able to continue breastfeeding. No weight gain, sex drive is fine. No dryness that i've noticed. Then again it's only been a month. But all these comments on here kind of scare me so i don't know if there'll even be a second shot in my future F 29 6 weeks
2/9/2009
 4  Birth Control Absence of period for 3 years (which has been GREAT), decreased sex drive, weight gain (which I was able to correct through diet and exercise) I had horrible periods before the shot (even on birth control), and being without any periods at all for the past 3 years has been a real blessing for me. I did gain some weight, but I was never a thin person to begin with. I certainly wasn't exercising and was eating constantly...which a sure-fire way to gain weight regardless of your metabolism or your body type. I lost over 50 pounds by changing my attitude about what real hunger actually is versus eating out of boredom or emotional issues. (I recommend hospital-sponsored weight loss programs for serious weight issues.) I just think you have to do your research before deciding on what birth control is right for you. And if you go on Depo, be vigilant about what you eat and how much you exercise...especially if you are not an active person in the first place. Just because you are thin now doesn't mean that your body will always stay that way...drugs or no drugs. I'm no doctor, but if you have a history of any kind of mental issues, I F 29 3 years
1/17/2009
 4  birth control Took Depo for 10 years...no period at all for a whole decade!!Side effects...decreased sex drive, decreased breast size F 29 10 years
11/10/2008
 4  Birth control/Endometriosis Mood swings, hair loss, weight loss Started shot in 2010-2011 to treat endometriosis and PMDD; after first shot my cycle stopped and I dropped weight from 156 to 143 lbs. Weight never fluctuated any more than 1-2 lbs up or down. Stopped shot in 2012 and got pregnant almost instantly with my son (after being told I might not have children due to untreated endometriosis). Went back on depo at postpartum visit October 2013 and have not missed a dose since. Starting to notice that I have rather frequent and aggressive mood swings and persistent depressive moments. Depression runs in my family however Ive never experienced a near constant state of depressive rage like I have now; even my PMDD only occurred as it should before my period. Will be discussing with dr whether or not the shot could be affecting my moods. F 29 1.5 years
1 dose 1X O
3/16/2015
Email
 3  birth control Headaches, appetite increase, blotting and weight gain F 29 10 years
3 months
4/29/2014
Email
 3  Birth Control I did not receive a period for the duration I was on Depo. I started Depo in May 2001 and my very last injection "expired" on October 11, 2008. I did not receive a period this entire time, which I really enjoyed. I discontinued this med because I felt like I was bipolar on it. My mood swings were TERRIBLE. Now that I've been off if it for 8 months, my period still has not returned. I feel better (mood wise) but I still feel terribly abnormal because it's taking so long to get my period back. I'm now starting Aygestin to induce a period. Keeping my fingers crossed that depo didn't screw me up for good. F 29 6.5 years
6/1/2009
 3  Pregancy Prevention Tired, weight gain, sore boobs, lack of sex drive. I can't take the pill - it makes me crazy. :) So I figured I'd try the shot; I've had 2 so far. I seem pretty tired all the time but that's not stopping me and could also be compounded by my career and stress. I've also gained weight which is worriesome since I'm an athlete and work out all the time and thought I could prevent the weight gain. It came in the 3rd month of the 1st shot, almost over night, but I'm determined to manage that with my diet and exercise. I haven't had the mood swings or depression others speak of and that was my problem with the pill. I do notice a lack of libido (not an absolute dead libido), which sucks, obviously, but my boyfriend is aware and we just try to do different things to make me excited. My boobs do get sore but typically only right after the shot and only for about a week or so, it tends to go away after a while. So I'd say even with the fatigue, weight gain, slight lack of sex drive and soreness of boobs sometimes - the shot is still better than the pill and condoms (and I tried those patches which were nasty) and better than getting pregnant. Hopefully after your body gets used to the hormone, these symptoms will subside. I'm going to give it the full 9 months (3 shots) before I make a decision about it. F 29 4 months
5/20/2009
 3  Pregnancy Prevention numerous fainting spells, heart palpitations, loss of libido, memory loss I began taking Depo when I was 16 (in 1996) and took it faithfully for 9 years. During my teen years, I had many fainting spells and heart racing. We never related it to Depo at the time, just teenage hormones. I didn't have a period for years! I trusted the doctors that this wouldn't be problematic in the future and it was pretty nice not to have to deal with that. I got off it to get pregnant which happened within 6 months. No complications there. I have a 2 year old and a 3 year old and didn't have any problems. I breastfed both for the first year of their lives and no problems there either. I now have a terrible memory, which started in my early 20's. I'm not sure if it's directly related to the Depo, or other events, but it's there nonetheless. I haven't had any bone density tests, which I should obviously do since I was on it for nine years, so I can't comment on those effects. Overall, I don't expect any drugs to be free of side-effects. I do wish that the doctors wouldn't be so quick to give a young kid a drug that's fairly new to the market. I've included my e-mail if anyone has any questions. F 29 9 years
3/31/2009
 3  birth control no period, acne I was on depo for 5 years and thought it was great because I never had a period. I was young so didn't really have much sex drive anyway. Didn't gain weight but started breaking out and am still dealing with that 10 years later. The only problem is that I have been infertile for the last 10 years and that definitely does not run in my family. The osteoperosis part scares me as well...haven't been checked yet though. It worked as far as birth control but I do not recommend it-the side effects or even potential side effects are not worth it. F 29 5 years
2/2/2009
 3  pregnancy prevention loss of sex drive;breast tenderness; weight gain (from 130 to 165);cyst-like weaps in vaginal area; unbalanced Ph (sweaty underarms and vaginal area; alot of water retention in legs and feet;mood changes; headaches; weak/painful joints This is a great product but is definitely not designed for the long term! stop it all together. I was due to recieve another injection in February but i decided to stop getting them.I was taking birth control pills prior to getting the shot because i was having problems with ovarian cysts. My doctor suggested that since i began having problems with the pill that i try depo. He did warn me about the risk of loss of bone density and i knew that i didn't have strong bones, so i took a risk. I was willing to work around the other changes that my body was experiencing but the weight gain has gotten out of control along with the decreased sex drive. It has truly caused a problem within my marriage which is not cool.I was relieved to see the postings on this site because im not alone. Alot of women are or have been experiencing the same side effects as i am. I thought that the changes i was going through were due to age but i see that is not the case. My recommendation to anyone F 29 14 months
4/26/2008
Email
 3  To prevent pregnancy I got my first shot February 2007. I just got my 4th shot today. The only negative side effect that I may be experiencing is slight mood swings, but this may be caused by depression. However, a small amount of exercise daily really helps. I only menstruate if I wait too long to get my shot when it's due. My last period was 7/29 and I got my shot 7/31. It was light and only stayed on a few days. I am Black and my hair gets very oily nowadays, but that's no problem because my hair is growing like wildfire! I am on the think side and wouldn't mind gainaing a few pounds......that's the one side effect that I want that I haven't gotten. I woouldn't mind a cool ten pounds or so. I really think it depends on the individual. I've had friends who've had horror stories about Depo and just as many who have no problems with it. F 29 9 months
10/22/2008
Email
 3  BIRTH CONTROL WEIGHT GAIN, LOSS OF SEX DRIVE, WAS ON IT FOR 7YEARS. WENT OFF LAST YEAR AND IT TOOK 1YEAR 1MONTH TO GET MY FIRST PERIOD.NOW I AM IRREGULAR, HOPE THAT IT WILL NORMALIZE SOON. AND I NEVER PUT TWO AND TWO TOGETHER THAT THE LACK OF SEX DRIVE WAS B/C OF THE DEPO. WONDER WHAT ELSE F 29 7 years
3/28/2007
 3  birth control Viginal dryness (I'm 99% sure it's because of depo); aching and cracking joints and bones (I'm only 29, I feel like an old lady); difficulty maintaining weight; irrational moods. I have been on depo a few times for about a year each time and then come off it for perhaps a year. I do not have any bleeding with it which is one up side, the other up side is contraceptive. I'm convinced it's the depo which makes me feel depressed, angry and irrational, I wasn't like this before and I have no circumstances for feeling that way. I find I feel happier about 10 to 12 weeks after the injection and am seriously thinking of coming off it, and to hell if I get pregnant (although my boyfriend will not be pleased). I go to the gym 2-3 times a week, do yoga, and walk a lot. If I have a few days off from exercise my weight creeps up, even though I only eat 3 healthy meals a day and don't drink much alcohol. I'm also worried that if I stay on it for too long it will affect my fertility and I really want kids in about 2 years time. I have few alternatives: The pop pill gave me excrutiating breast pain, the mini pill cannot be prescribed because I have occasional migraine F 29 18 months
12/13/2006
Email
 3  Birth Control Mood swings, acne/oily skin, weight gain. Liked Depo whilst i was taking it, although it made me have psychotic mood swings. Howevever, now 9months since last injection, my husband and i are trying to start a family, I still havent had a period, but have had all the cramps. Also i have had hot flashes and achy bones i have found myself very lazy as well. Although these side effects have only recently appeared so it shows how long depo stays in your body. I just wish i could rid it from my system and get my periods back. Feel very depressed at times. F 29 21 months
11/28/2005
 3  Prevent pregnancy Gained 20 lbs over first 2 years, somewhat decreased sex drive, spotted for 1 month after first shot, no period after that, stronger BO, unwanted facial, breast and body hair growth, delayed return of periods. I loved it while I was on it but I haven't had a shot in about 1 year now and had my first period about 1 month ago. I am concerned about the bone density loss and possible lack of fertility. I have dropped almost 10 lbs of my weight gain since stopping. I would not reccommend this. F 29 4 years
11/24/2005
 3  Severe mood swings and bad periods Decreased sex drive severly but other then that it helped with the mood swings & and painful periods whenoffnthe shot I feel normal in the intimate dept but horrible the rest of the time with painful periods and have then every other week F 29 10 months
Shot
7/19/2012

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