DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Prevent Pregnancy Horrendous. Became severly depressed (never suffered from mood changes before - resourted to councelling), bad anxiety, loss of concentration, paranoia, Horrendous experience. Became severely depressed (never suffered from mood changes before - resorted to counseling), very bad anxiety, night sweats, loss of concentration, lethargic and in need of constant sleep, paranoia, complete loss of libido, very quick weight gain, constant light period for 9 weeks to date, found out yesterday I have loads of ovarian cysts and am not ovulating. Took the shot once and will never touch it again. F 31 3 months
1X AN
6/26/2013
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 1  Birth control severe depression, tiredness, mood swings,irritability, headaches, migraines, leg cramps, stomach pains, loss of sex drive First month on it I was sick a lot, but the next 3 months were really good. No side effects at all. By the 4th month, I suddenly became depressed and experiencing frequent migraines. Depression & headaches got worse, started experiencing more symptoms. I'm tired all the time, I'm in therapy for anxiety/depression, I'm just not happy anymore. I seem to have a lot of seemingly random symptoms, different kinds of stomach pains, constant feeling of unwell, I cant concentrate, I get very mad over the slightest things. I've been spotting almost everyday for a month now, now there's lingering abdominal cramps. Before this, I was in very good health. Now I'm just not myself. Its terrible feeling sick all the time. What did I do to myself? F 31 8 months
8/1/2009
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 1  forgetting to take pill were do i start!!!! loss of sex drive, hair loss, moods, panic attacks, depression, painfull sex, would love to hear from any body who could tell me when will i ever feel normal again? F 31 18 months
10/22/2009
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 1  pre-essure procedure I've had 2 shots. I had 3 weeks of horrible spotting and shortly after the first shot, severe joint pain. I couldn't sleep at nite, kept waking up due to the pain in my shoulder. Went to physical therapy, and 2 weeks later, the other shoulder began waking me up at night. Now my hip has begun. Also, lack of sex drive and dryness. Birth control works well when it makes you uninterested in having sex with your husband. I hate depo. My doctor told me she was giving me the shot to thin my uterus prior to the Essure procedure. She gave me nothing to read, no choice. No information on any possible side effects. I had been on the pill for 10 years. The procedure didn't work, she couldn't get the coils in my tubes. So, my husband had a vasectomy, and I had to take another shot to last until he was clear. At the time, I didn't realize joint pain was a side effect. Had I known, I would have demanded that I stay on the pill. I thought I had twisted my shoulder somehow. I hadn't. I am very angry, and I feel like I've been ambushed by my doctor and the FDA and the company that makes this poison. My joints had better heal when this wears off. There had just better not be any permanent damage. F 31 6 months
4/7/2009
 1  To prevent pregnancy Severe mood swings, loss of sexual drive, hair loss I took Depo after my first child was born about 3 years ago and swore I would never take it again. However, in June I had another baby and because I was having the Essure procedure for permananet sterilization, my doctor insisted I have the depo shot again so I wouldn't get pregnant. I HATE IT! I am a total raving lunatic on this stuff. Everything my hubby does irritates me, I have no patience with my older daughter, I react negatively to things that I normally would be fine with. I also have absolutely NO sexual desire. I couldn't care less about sex or intimacy of any kind. My poor husband is tired of "pity sex". Once this shot wears off (my first one) I'm getting off this stuff and never looking back. Yeah, it's great not to have a period, but I'm tired of acting like satan all the time, and I want to feel desire again!! F 31 2 months
10/1/2008
 1  contraceptive severe mood swings, loss of sex drive, hypertension, bloating, spotting I am furious the nurse practitioner I went to did not tell me the horrible side effects of this poison! I feel like I'm going crazy! My wedding is in a week & it was nearly postponed because of the severe depression tailspin this poison put me in! If you have even the slightest bit of history of depression either with you or running in your family - DO NOT TAKE THIS DRUG! I haven't dealt with depression for over 10 years and in 3 days this put me in such a state I really thought I was going crazy. My fiance knew this wasn't really me and I'm praying the side effects lessen, I do feel a little more normal as days progress, but my fear is any little thing could set me off. I also don't want him to kiss me or touch me, which is devastating because we've been waiting so long to be together sexually and now I don't have the desire! what?! why didn't the dr tell me this stuff?! I will be going to the patch - and not for the next shot......does anyone know HOW DO I DETOX FROM THIS POISON? I wish I would've researched first, instead of trusting someone else with my mental and physical welfare. hard lesson to learn... F 31 6 days
5/11/2009
 1   Gastric reflux, stomach upsets, fatigue, nausea, diarrhoea and a general unwell feeling. My doctors keep saying my symtons were IBS... I knew it was Depro.. also it has been 6 mths since it wore off and I still have symptons and no period.. Shocking F 31 120 days
5/3/2009
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 1  birth control severe weight gain, decreased sex drive, hypothyroidism, chronic yeast infection, dryness and vaginal irritation, pain with sexual intercourse, very irregular periods I took depo for aprox 5 years which was the biggest mistake of my life. I continue to have sig. problems after stopping this shot. I have not been able to get rid of chronic yeast infections and dryness in the vaginal area since being on the shot. I also continue to have significant pain with intercourse. I now have multiple folicular systs and am having difficulty trying to become pregnant. My weight gain due to the shot has also caused multiple problems. Overall this has been a very nasty drug and has caused multiple ongoing problems even though I have been off of the shot for almost 5 years now. Would like to know if there is a class action suite being persued against this drug. F 31 5 years
5/31/2009
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 1  Birth Control Being on Depo was terrible. The doctor warned me about weight gain, but I never expected to gain 15 pounds in 6 months. I spotted continuously. I switched back to the pill 1 month ago, but worry that I'll never lost the weight I gained on Depo. F 31 6 months
4/15/2004
 1  birth control weight gain. 20 lbs in 6 months. migraine headaches, constant and often severe neck pain, sore stiff muscles, achy joints, mood swings, Did i mention weight gain? The information given by my doctor and the leaflet are very misleading. It does not mention these kind of serious side effects. Who knows what else this drug has done to me. F 31 6 months
3/9/2004
 1  birth control 13 pound weight gain in 4 months, mood swings, acne 7 years ago I lost 30 pounds with Weight Watchers. After the shot I started to gain 1-2 pounds per WEEK. This was extremely frustrating for someone who has tried so hard to maintain a weight loss. No one can tell me I'm munching too much because I keep track of everything I eat and all my exercise. I got my shot on February 2 and as of last night I've gained 13 pounds. It has been over 4 months since I got my shot and I'm still gaining weight. I will never use this again. We were considering another baby eventually but I still haven't had a period and from what I'm reading here, it could be a long time before I do. I've had some of the mood issues but certainly the biggest problem for me has been the weight gain. I'm hopeful the drug will start to leave my system soon and I'll be able to start losing weight again. Fortunately, I do not have other problems, like heavy bleeding or extremely painful periods. But I do have a history of blood clots so my birth control options are F 31 1 times
6/12/2007
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 1  eliminate period weight gain, lack of sex drive, painful intercourse, bleeding during intercourse after having my tubes tied I experienced a major increase in monthly flow, I went on Depo for the second time, I got pregnant on it the first time, to regulate my period. Within the first month after the shot the period was gone, however I did receive something in return. Every single time I had intercourse with my husband, or even without penetration, I would bleed, and I don't mean a little bit, enough that it was a major concern. I talked to my doctor about it, and she said that it couldn't be the Depo-Provera that was doing it, but after many tests to find nothing wrong, I chose not to get the next shot. It has been three months without it, and I have not experienced the bleeding since about a week after discontinuing Depo. F 31 1 years
4/12/2007
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 1  Birth Control & Endometriosis Hair loss, weight gain, night sweats, complete loss of libido, swelling of hands and ankles, severe mood swings. The ONLY good thing about this drug is that I haven't had a period since I've been on it. ... and my cramps which lasted up to 10 days before pretty much vanished. But, all the other effects weren't worth it!!! F 31 20 months
7/13/2007
 1  contraception weight gain, loss of libido, hair loss, bartholin cysts, bleeding between periods, abnormal smear results-CIN 3 F 31 3 years
4/26/2005
 1  contraceptive severe depression, loss of appetite AWFUL experience with this drug. I was so emotionally messed-up during the three months I was on this drug that I was diagnosed with Borderline Personality Disorder and I had to take "Incompletes" in a couple of college classes. The worst part: once you get "the shot" you're stuck with the side effects for 3 months. If you've ever been diagnosed with depression, even if you're fine before considering this drug, please discuss other options with your doctor! F 31 90 days
5/19/2007
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 1  Birth Control Weight Gain, Impossible to lose weight, severe mood swings to the point where I thought I was suffering post natal depression, no sex drive whatsoever. Felt like the end of the world most days I was due to have my next injection today but told the nurse ponit blank I didn't want it. Her comments to me basically implied that everything I told her was down to me and not the side effects of the drug. She was very reluctant to not give it me. I have now insisted that they try the coil. Fingers crossed I'll feel better! They shouldn't make you feel guilty for wanting to come off it. F 31 12 months
5/22/2007
 1  prevent pregnancy severe lack of sex drive and vaginal dryness so that i actually dreaded the thought of having sex with my boyfriend as i couldn't bear him to come near me, extreme irritability and depression and spotting throughout most of the 3 months i was on depo. The irritability was the worst side effect for me since i am a very laid back person, nothing fazes me but it got to the point where i had to sit with my ipod on at work all day long to shut everything out as every single little thing annoyed me to the point i would feel a rage building up inside of me which i have never in my life experienced! Unlike most people on depo though, i didn't gain any weight i came off the depo after only 3 months due to the side effects and expected them to disappear after stopping it. They didn't! the irritability continued although i am getting back to my old self now. I also experienced more symptoms coming off depo than i did on it. I have been off depo for over 6 months and during the past 3 months i have experienced pregnancy symptoms such as cramping, severe nausea, fatigue, acne (i have never had spots before), bloating and the most intense cravings for food (mostly chocolate) which i struggle to keep under control and have only managed to keep my weight down by jogging / gym sessions 6 days a week. I know i am not pregnant, I have done numerous pregnancy tests which where all negative. I can only assume this was the result of my hormones trying to get back to normal. The symptoms do now seem to be tailing off with only the odd bout of nausea now and sex drive is coming back. The only side effect i was warned about from my doctor was slight weight F 31 3 months
11/2/2008
 1  easy method of birth control loss of sex drive, loss of periods, weight gain, extreme mood swings I only took the shot a year and have been off it almost a year and still have not had a real period. My doctor says it can take up to 18 months for it to be out of your system, which if I had known before, I would not have taken it. Now we are trying to have a baby and clomid has not even been able to make me ovulate again. I'm mad and frustrated that I did not know much about the horrible side effects before and now I just have to sit and wait for this junk to be out of my system. I just hope that someday soon it will be out of my system so that I can feel normal again. F 31 1 years
11/20/2007
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 1  Birth Control Went from having a healthy sex drive to none at all, annoying break through bleeding - often during or right after sex, mild depression, weight gain(which I didn't really care about),trouble sleeping and mild anxiety issues(to name a few of the most troublesome ones) After realizing that it was possible that the shot was the key to all the health problems I'd been having I promptly went off it. Since being back in the pill my sex drive has bounced right back (whew) and I am seeing that the other issues I was struggling with were actually linked to the depression, which was caused by the side effects of the hormones/lack of hormones in the shot. I did alot of searching to find the BC that was right for me,(continuous use bc pills)and it works. I would recommend everyone take some time to search around for what will work best for your body, it is so worth it. After all EVERY ONE IS DIFFERENT,AND IT HAS EVERYTHING TO DO WITH WHICH HORMONES WORK FOR OUR BODIES AND NOTHING TO DO WITH HOW MANY COOKIES WE'RE EATING - as someone a few posts down so disrespectfully put it - F 31 3 years
10/17/2007
 1  birth control weight gain (30 lbs), constant hunger, depression and anxiety, paranoia, mood swings and irritability, complete loss of sex drive, vaginal dryness and painful intercourse, dizziness, cramping and gastrointestinal discomfort, stomach bloating DO NOT TAKE THIS DRUG! It is poison to your body. From March-November 2008, I gained 30 pounds. I have not changed anything in my lifestyle other then that I am hungry ALL THE TIME while I am on Depo. If I don't eat I get light headed and terrible headaches. I also had a complete loss of sex drive and mood swings and anxiety that threatened my marriage. These were completely new and I had never had this problem before. Every time I tried to talk to my doctor or the nurses, they acted like I was crazy and said my symptoms couldn't possibly be the Depo. Now I find out that my doctor didn't bother to counsel me on the fact that I should have been taking extra calcium this whole time and I have to get a bone density scan to be sure I don't have osteoporosis and I'm 31 years old! If you do research on this drug you will see that it never should have been approved by the FDA. I trusted my doctor and thought she wouldn't give me something that wasn't safe. I was wrong. Don't let yourself be t F 31 6 years
11/19/2008
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