DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Avoid hysterectomy for Hyperplasia Mood swings, loss of libido, extreme vaginal dryness, painful intercourse After extended bleeding and spotting for the first few months, all seemed okay except lack of sexual interest. Mentioned to doctor who said it was probably stress. It did stop the pain of suspected endometriosis. After a more than a year, the dryness and pain durning intercourse has made me reconsider the hysterectomy. It's scheduled for this Tuesday. I felt 100% better hearing that others had similar problems and that it was not all in my mind! F 46 1 years
10/15/2006
Email
 2  to control heavy periods Today is May 10th, I've had bleeding since January 27th. It doesn't seem to be an end in sight. I have now had to begin taking iron because I have become anemic. Obviously, there's no sex. I thought this medicine was supposed to stop periods. F 46 2 times
5/10/2007
 1  birth control after 3 month i gained 12 pounds!! i don't eat very much and i walk daily and still gained. F 46 3 months
5/5/2007
 1  painful periods 2 days after the shot had rectal bleeding , which i never had befor plus acne, 18 pound wieght gain ,swelling of hands and feet,bloating and all round discomfort leg cramps at night. would nerver recomend to anyone F 46 1 days
11/9/2007
 1  help ease menopause Loved it for first 3 shots...then had several UTI's, pain when urinating, severe depression, terrible head aches, swelling in hands and feet, ache everywhere (especially in back and ankle where I'd had injury in the past) I've been to several specialists, had a CT scan, a scope of my bladder, sonogram, they found NOTHING...then I go to St Luke's hospital and find out it's the damn depo. I am miserable...I miss lots of work, scheduled for hystorectomy next month and hope like hell I get back to normal when this poison gets out of my systom. F 46 18 months
2/18/2009
Email
 1  PMDD Depression, anger, rage, mood swings, hunger I had been on YAZ birth control pills for 2 months to see if it would help with PMDD. At my follow up appt, my doctor suggested depo provera as a way to ease the PMDD symptoms. She told me the side effects could be weight gain and spotting. Within a few days of the shot, I felt like I was going through PMDD!! Instead of reducing the symptoms, it GAVE me the symptoms. DO NOT TAKE THIS WITHOUT SERIOUSLY RESEARCHING THE SIDE EFFECTS. I made a hasty/desperate decision in the doctor's office and I regret it terribly. I cannot wait until this leaves my body. F 46 7 days
5/18/2009
 1  stop menstral flow I have bled everyday for 3 months.Its horrible.i wonder how long this will last? I do not recommend it!!! F 46 3 months
9/16/2009
 1  Only option for birth control No sex drive,moodiness and very vile attitude,too many hot flashes and severe cramping. If I had found this site before my first shot there is no way in hell I would have taken it.I got my first shot 8-20-09 and on 8-31-09 I started bleeding and 56 days later I am still bleeding,some days so heavy I use diapers to keep from bleeding all over the place.In two months times I have purchased 7 months worth of pads and tampons,I am afraid to leave the house out of fear of soiling my clothes.I started my first period when I was 12 and never had a cramp in my life,noe the cramps are so bad I just sit/lay in bed,hold my stomach and rock.My patience is short and everybody I know has started calling me mean,thank God I don't own a gun.The only reasons this works as birth control is because,#1.you are bleeding everyday,#2.your attitude is so stank,no man will come near you,#3.You have no desire to have sex and #4.If you have a man he will leave you beacuse no man will believe that his woman is having a 56 day period,I will definitely not be taking the second shot,I would rather have 20 kids than to go through this.The prayer that I pray everyday,all day is Lord please stop the bleeding.Thank you for such valuable information and I am so glad that I am not alone in this. F 46 2 months
10/25/2009
 1  To stop my periods My periods are worse than ever, have been continuous since Jan 11. Have had sweats, bad skin and most of all horrific moods and depression Do not take this drug it is the worst thing U have ever done, can't wait till it is fully out of my system. F 46 10 days
3/4/2017
Email
 1  Endometriosis Depression, anxiety, nausea, rage, harmful and suicidal thoughts. Weight gain, barely ate but went from a size 10 to a size 24 in three months. Feeling of loss, sadness and violation. Mood swings. Loss of appetite for everything. Loss of self confidence and self worth. I could no longer see a woman in the mirror just a thing. Dizziness, exhaustion, the list goes on. I actually took this when I was 21 but the mental health effects stayed with me and I have lived in Hell for 25 years. I wake up with no desire to live the day. Spend the day waiting for it to be over and cry myself to sleep. I met a wonderful man but still no sign of children and no idea if I can ever have them again. I did not ask to have this drug, I was threatened with a hysterectomy if I did not take it by a consultant who can no longer practice. This drug has robbed me of 25 years and almost destroyed my life. Do not let it do it to you. F 46 90 days
10mg 1X day
5/5/2021
Email
 5  Contraceptive None other than fertility took longer to return but then I was on it forever!! 13 yrs. (Started it 1990) & am 47 now (2020) It worked great for me. No periods. No side effects other than extended fertility returning (after Had come off it) F 47 13 years
150 4X O
10/24/2020
Email
 5  Stop unwanted periods In the first 3 months (October 1996)irregular spotting, felt more emotional (easy to cry). But, after the second shot (3 mths later), no more spotting and emotions are normal.I get mine every 3 mths since. Love not having my period. I was concerned about my bone density from the fine print warning, so this year (2012), had a Cat Scan that showed I have better than average bone density. Now let me explain, I eat dairy and take a multi vitamin and magnesium and Vitamin D (5000 iu a day), so I am absorbing my calcium and have healthy bones. I'm 47, by the way. I eat nutrient dense foods, including animal proteins eggs and so on. I think having a healthy diet has helped me. I contacted this company and they got back to me the same day. Good service. F 47 5 years
1X O
8/22/2012
Email
 5  1st for birth control now fibroids on for 7 years for birth control off for 2 years and had heavy bleeding/fibroids went back on last 5 years to stop periods and cramping and feel great - no periods or pms, some mild spotting only occasionly before next shot is due. I was overweight when I got the shot and have gained weight. I so enjoy not having to deal every month with cramps, pms and severe bleeding. I got a bone density test and it was normal I do take 1500 mil of calcium a day. The 1st year on the shot your periods will be abnormal, I spotted continually for 9 months, but then they stopped and I was fine. F 47
1X O
10/13/2011
Email
 1  painfull periods, birth control anxiety/panic attacks, irrational fears, low blood sugar, weight gain, hair loss, feel like losing it I posted here on 2/11/09.Here I am 2 yrs later with THE SAME HORRIBLE SIDE EFFECTS! In the 3 and a half yrs since the first panic attack I’ve seen all kinds of doctors and been on all kinds of meds: 2 GPs who shoved antidepressants and benzos down my throat, 1 endocrinologist who told me it was all in my head, 1 psychiatrist who blamed it on stress, 1 acupuncturist who took my $600 and he was happy, 1 homeopath who did not even follow up with me after one missed appointment. NOT ONE OF THESE IDIOTS CONNECTED THE DOTS and thought the Depo could have triggered the symptoms (they were all informed I was on it for over 2 years).Thousands of dollars down the drain, years of suffering,false hope,humiliation. My hormones are screwed up,I feel like I’m on a rollercoaster but can’t get off.Absolutely devastating.Who's going to give me back all these years of suffering,of not being able to go places by myself because of these irrational fears I NEVER HAD BEFORE?If thousands of women are still experiencing devastating symptoms and sites have been created to report them,why is the drug still out there?I read posts from the 1990s and here we are in 2011 and women are still poisoned.has a lawsuit ever been filed?We're voicing our pain and suffering ,"BIG PHARMA" and FDA are laughing at us, poor stupid women "genetically insane". I'm now in the compassionate hands of a naturopath.He's really my last resort before the madhouse. F 47 28 months
no idea 1X O
2/14/2011
Email
 1  birth control irritability, sad, withdrawn, mean, constant brown spotting, then an unexpected heavy long-term period. extreme fatigue to the point where i stopped looking into the mirror because of the bags under my eyes. absolutely zero sex drive. im so upset that my doctor recommended this poison to me. it has changed my life. i am not the same vibrant, beautiful, happy person i was before i started this in August. I am now not speaking to my sister, my best friend, i broke up with my boyfriend because i couldn't stand to be looked at like a sexual being. i feel extremely ugly. in the last month, i dyed my blonde hair to dark brown, ordered wrinkle cream, joined a gym because of a sudden low self esteem (i was but six months ago called "hot" which is unbelievable to me now when i look into a mirror). i sit at home alone. i don't want to be around anyone. im not kidding. this is a very dangerous drug. i only wish that i had seen this website before i started. i was only warned about weight gain and bone loss. i am printing out this entire blog to show my gynocologist so she doesn't ruin anyone else's life. :( i pray to god that it gets out of my system fast. im going to try a detox - if i can stop bleeding long enough to get to the store. 47 5 months
1X O
1/21/2011
 1  heavy bleeding Within the first month - continuing into the second month depression, mood swings, acne, anxiety, extreme fatigue, loss of interest in anything, blurred vision, cramps/spasms in feet, back pain, muscle soreness, etc. Cure is worse than the condition. Would not have another shot ever! Have only been on it 2 months and regret having it! F 47 2 months
4/27/2006
Email
 1  to stop heavy bleeding I spotted everyday for most of the 3 months....I did not continue taking Depo Provera. My emotions were wild, had migraines much more severe and often,I screamed at my boyfried regularly, moody!, argued over the smallest things! Everything seemed to "get on my nerves bad". I was nicknamed The Monster, because Norm had never seen me act this way before. My sister had also tried it, and I listened to her and her 2 teenagers describe "what a mean witch" my sister was. I have been told I am prone to Osteoperosis, and my doctor did not ask me anything about this. She did not warn me of the black box warning on the shot. I took only one shot of DepoP. I was supposed to go for the second shot on April 7th. I had a period in May, but now it is July 6 and I still have not had another period, just some spotting. F 47
7/6/2009
 1  Fibroids Insomnia., abdominal pain, anxiety, headache, tiredness . Horrible experience ! F 47 2 months
1X day
4/24/2024
 1  Was encouraged to by Dr for the sta Migraine headaches ,violent mood swings, bled for an entire year , low iron,weight loss ,to the point of looking anorexic,fatigued, numbness in my pinky finger on one hand and complete numbness of my other, lazyness -not my nature. Severe depression ,very suicidal I bled for an entire year. I was treated as if I was crazy for wanting to be seen to find out why but they wouldn’t see me untill I stopped bleeding . I just wanted to know that I wasn’t dying or that something wasn’t seriously wrong with me. I called a lot of different drs and was told that the depo shot had no such side effects that I should see a shrink and go to anger mansgement. Im not an angry person.this was 23 years ago and im still suffering from many of the side effects like headaches, depression , fatigued,and pain in my neck. This is how a woman is treated in our day and age and have been for centuries. The glass breast implant,men thought that was a great idea untill the glass broke and she died F 47 6 months
Injection
12/12/2016
Email
 5  Birth Control Very slight weight gain I am 47 and decided on depo provera last year since I previously had breast cancer and most forms of birth control not an option for me. Depo has no estrogen so I decided to try it on my physician's recommendation. Had continuous brown spotting for the first 3 months on it which was extremely annoying, but after that, no side effects to speak of. I originally weighed 113 lbs when I started the depo, and after a year and a half weigh 117 lbs so not really sure that my slight weight gain is a direct result of the shot. I really like the convenience of a shot every 3 months and have none of the numerous side effects most posters here have written about. I would highly recommend this as an effective, easy form of birth control. F 48 1.5 years
8/14/2008

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