DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth Control Decreased interest in sex, extremely painful intercourse. The first 1 1/2 years on depo were great. No periods - that's why I went on it in the first place. However, as time went on I noticed that sex was becoming a bit painful. It got to the point that when I went to the doctor about it she could barely examine me as it caused me so much pain. She told me it was because of the Depo. I am now waiting for the shot to wear off and hope I get back to normal has quickly as possible. I would NOT recommend that anyone take this. This side effect has been horrible. I've been doing a lot of reading since this has happened to me and realize that my hair loss, memory loss, and irritability may have something to do with the Depo as well. I think this is a nasty drug, and doctors need to be more upfront in telling patients about the side effects. F 42 3 years
4/20/2004
 1  birth control horrible depression, weight gain, non-stop bleeding, hair loss, extreme dry skin, no sex drive, depletion of breast milk, whole body aches and cramps At my 6 week check up after the birth of my son, my doctor discussed birth control. I didn't feel like I needed to use anything given my age (42) and medical condition (PCOS), but we decided the depo shot was my best option since I was breastfeeding. I was not informed of any complications and had previously taken birth control pills with no problems. Everything was fine until about six weeks after the shot. I had a period that lasted three weeks. My breast milk supply was extremely poor where it had been very large. I finally stopped the period and had two weeks of feeling okay, then like an idiot, I believed that I needed to take the second shot. I have been having a period since Aug. 26. It gets heavier everyday and I am an emotional wreck. I cry at the drop of a hat, I don't want to do anything. I hurt from head to toe and my hair is coming out by the handful. I would never under any circumstances recommend this medication to anyone! Find something else! F 42 2 times
10/6/2009
 1  Birth Control ****WARNING POISON**** Will ruin your life!!! Been on the Depo shot for 6 months as of 4/14/14 I will not return for my next dosage! I have spotted non stop after the third week of my first shot 4.5 months ago and for the last 5 weeks heavy bleeding every single day to date! I have breakouts in my face along with severe headaches, sleepless nights, anger and mood swings and fatigue. Every time I call my OBGYN to voice my concern the nurse tells me its NORMAL! DO NOT TAKE THIS POISON...IT WILL RUIN YOUR LIFE! I will soon begin to look for legal counsel that can represent all of us on an attempt to hold the manufacturer of this poison liable for all the harm it has cost. F 42 6 months
3/25/2014
Email
 5  severe dysmenorrhea during period I am on depo for 22 years and had NO side effects and NO period...now, at 43 I've suddenly started bleeding a little and have slight stomach cramps(like period pain)-suspecting menopause Best 22 years of my life F 43 10 years
11/4/2015
Email
 5  hated getting a period Weight gain,hot flush, But I'm js confused as to when I should stop cause of menopause F 43 10 years
11/5/2014
 5  birth control Low sex drive, dryness, itchy, mood swings, painful sex,breast tenderness,joint pain, night sweats,insomnia, bladder control,extreme anger, no period for 8 years45 pound weight gain, constipaton digestive problems,always congested. Not having s period for 8 years is awesome! I'm having a difficult time convincing myself to Change bc. I have noticed extreme anger issues, I hate everyone, I, ram surprised I am still married due to the anger and lack of sex drive, sex is painful and dry, and is without pleasure. A few days after having sex I feel like a bladder infection or yeast infection starts. My breasts have gotten quite larger from B to DD which would be great if they were not tender...frustrating! Extreme, extreme anger! Weight gain 45 pounds in 8 years. Best figure I've ever had, most people thought I was anorexic before. Dr. Has asked that I switch bc. If it helps sex drive husband will be happy. I hope the painful sex goes away, afraid of new mood swings with new bc and having s period, never missed that. Lack of bone mass was a new concern. Dr. Gave me the scan for ibonr loss I've been on drop For 8 yrs and I'm ok, but that was scary.. so new bc here I come. I would take depo again, my husband had learned stay out of my way when I tell him I will knock you out if you don't get away from asap! F 43 8 years
.? 6X O
8/10/2011
Email
 4  birth control weight gain, moodiness, no periods I love this shot. Estrogen based BC causes problems for me, this does not. There is a small amout of weight gain but that could be other factors also. Compared to others I have virtually no side effects. this is my second time on the shot, I did stop for several years to take a break from it as my Doc warned me that it was not ment to be a long term solution. I am noticing a difference this time in that I am getting the generic version of the shot so there may be something in that particular formula that is causing a few side effects. I was warned about possible effects by my doc before deciding to start back up on it. For me this is the best BC alternative. F 43 4 months
150 1X O
10/9/2010
Email
 4  to stop heavy bleeding No side effects while taking it. Have been off for five years and have broken several bones. It takes nothing and a finger will just snap. I shoe horses and ride all the time this is not a good combination. None of the medical staff that I have used ever even hinted that I would have major bone loss. I would rather have bleed and been bear bait then know that I can't even roughhouse with my children . F 43 12 years
1X day
11/11/2010
 4  fibroids Mood swings,low mood,irritability. This drug has helped with fibroid pain and bloating. 43 14 days
9/30/2019
Email
 3  Cysts on ovaries High bp, headaches, anxiety, panic attacks and agrophobia. F 43 4 years
1/29/2014
Email
 3  Birth Control Weigh gain, loss of sex drive, fatigue, mood swings, night sweats I was on depo for 2 years. At first, I'm LOVING IT, no periods.... awesome. Then over about 6 mo to 1 year, 30lb weight gain. Even tho I'm more active than I've ever been and have never had weight issues before. No matter what I eat or do, weight keeps creeping up!! Doc recommended I go off it for a bit and I doubt I'll go back on. Having been off it for almost 4 mo. I feel a bit of sex drive again. Thank god I have a patient and loving husband. Have dropped a few pounds. Anyway, I tried giving it the benefit of the doubt, but I do believe that the aforementioned symptoms were caused by the shot. I'm not convinced that it is necessarily evil, but also, not very convinced it is the best thing for you. I definitely had a lot of odd things going on with my body that seem to be subsiding, now that I am no longer taking the shots. I'm on the pill and will probably stay there. Plus there is the bone density loss thing. Not good. F 43 2 years
4/1/2008
 2  contraception continous periods Ive had depo shots twice now and in that time Ive had continous periods and stomach cramps, my doctor told me that my periods would stop what a laugh that was. I never know when the bleeding is going to start or stop am definitely not going back for another shot. F 43 2 times
1X day
1/4/2012
 1  very heavy prolonged period Terrible experience!! Almost stopped bleeding and clots entirely for a just under 3 weeks weeks. About day 20 bleeding heavy started again with bad clots and worst cramps in my life in my abdomen and back . Felt like childbirth! All over body aches like I had the flu. Dull headache, insomnia, extremely moody and fatigued. Called dr, scheduled d & c, got off Provera and put another birth control and pain med for severe cramps. About 2 1/2 days being off Provera, bleeding almost completely stopped, NO cramps, no headache or body aches, great mood! Calling Dr. tomorrow to see if I still need d & c. Not sure what to think...did almost stop my nightmare period but came back with a vengance!! Would NOT take Provera again! F 43 20 days
10mg 2X day
1/28/2012
 1  Prescribed before Essure procedure Moodiness, anger, complete loss of sex drive, constant dull stomach cramps, lack of appetite, constant bleeding, headaches. I was given this shot because I was having the Essure procedure done. I'm against hormones, but because my doctor recommended it, I agreed. I certainly wish I would have asked questions first! I've bled constantly the whole 12 weeks... some days it's heavy, some days it's not. At first it was a huge concern, now it's just a major annoyance! I've been moody and depressed the whole 12 weeks. I have zero interest in sex and that makes me angry! My only hope is that I actually go back to my normal self once these chemicals are completely out of my body!! My experience with this drug was not good, so I would NOT recommend this method to anyone. F 43 12 weeks
? 1X AN
2/23/2012
Email
 1  Birth Control Night Sweats, Depression, Cramps, Period for two months and no signs of stopping. I would not recommend. I think the number one side effect - prolonged bleeding should have been mentioned before I took this drug. Only thing they told me was that I wouldn't have any more periods. Have been on one since I got the shot September 9. Was in brand new relationship and this has since ruined that. Only reason I got on it was for birth control. Good birth control as you won't be having sex. Cramps the whole time too. Enough to drive someone crazy! F 43 2 months
1 X 1X O
10/31/2011
Email
 1  Birth Control More hunger (weight gain as a result),fatique, no sex drive, headaches, no period for 3 Mo. At first I didn't experience any side effects other than no period (not even spotting). After the first missed period I started noticing an increase in headaches, fatigue, lack of sex drive. I gained 10lbs. in 3 months and the fatigue was so disturbing that I decided right away this was not the birth control method for me. What's been even worse is going off of it. I've had non-stop spotting for 4 weeks now, swollen breasts, cramping. It's worse than the changes I went through during pregnancy. This cannot be good for your body -- steer clear of this birth control alternative! F 43 3 months
1X O
2/25/2010
 1  cysts and heavy bleeding This shot is poison! A few weeks after my first shot began having dizzy spells and abdominal pain...took the second shot 3 weeks ago abd truly regret it. Been to the emergency room for heart palpitations chest pain and difficulty breathing... been to my primary doctor now who thinks sypmtoms may be related to anxiety with the Depo shot... as i sit and write this review im on a heart monitor for 7 days to rule out anything cardiac.... been severely depressed, cry atleast once a day over not feeling like myself. This shot is the worst drug available.... cant sleep, cant eat without feeling nauseous! Not to mention the extreme fear felt from the anxiety! I can't drive or even get out of bed most days! Worst part is when I called my OBGYN they said there is nothing they can give to counteract the shot .... just have to wait for it to get out of my system! TRUST ME ..... DO NOT EVER TAKE THIS SHOT! IT IS THE WORST EVER AND SHOULDNT BE ON THE MARKET! F 43 4 months
5/21/2013
Email
 1  Pregnancy Prevention insomnia for the past 4 nights unable to sleep. Received frist shot March 9, 2012. Menstrual completely stopped, UTI, constant hunger pangs. Have no plans on receiving second dose. The sleepless nights are horrible! F 43 1 months
1X day
4/12/2012
 1  Cysts and Heavy Bleeding I last posted my experiences with this shot 3 weeks ago. Since then have been taken to the ER via paramedics for severe heart palpitations, chest pain, and trouble breathing. After more blood work, another EKG and. cat scan of my heart and lungs to rule out possible blood clots- the ER doc felt is was severe anxiety. As a resiult, my primary care doc has put me on Serax to try and control the anxiety attacks. Prior to my Depo shot I was healthy, active, and normal. Now my life has been reduced to my bed and couch. I have not been able to work for the last 4 weeks, cant leave my house. Depression, crying every day, extreme fatiigue, and horribly nauseous - lost 12 lbs in 3 weeks as a result. This shot has destroyed my life. Im told there is nothing that can be done - just have to wait until its out of my system... Two more months! TRUST ME DONT EVER TAKE THIS SHOT!!!!! I'd much rather deal with extremely painful and heavy periods than go through the HELL I'm experiencing now! The risk isnt worth it and the side effects are life altering. F 43 4 days
6/6/2013
Email
 1  to control heavy periods 5 months of bleeding, weight gain and loss of sex drive I started bleeding one month after my first depo shot and it hasn't stopped since. My doctor recommended getting a second shot early to stop the bleeding, but it didn't work. After 5 months of bleeding, he now has me on 14 days of estrogen. It's my first day so I don't know if it's working or not. I also completely lost my sex drive and gained about 10 pounds. I would not recommend this drug to anyone. F 43 2 times
12/27/2004

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