DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  pelvic congestive syndrome Complete loss of libido, weight gain, severe anxiety attacks, depression, urinary infections, pelvic infections, severe mood swing, digestive upset, constipation, nausea, headaches, developed hypothyroidism just while on it, weakened immune system, urinary irritation constantly, withdraws, upon getting off it, lack of menstruation even after stopping. I would recommend that NO ONE use this as a form of b/c method. It has ruined my life and cause so many health issues. while being on it I have never had so many health issues that sent me to the doctor back and forth and to the emergency room. My tubes are tied so I only used it as a method to calm my pelvic congestive syndrome and wished that the pcs was the only issue and rather had dealt with only that instead of all the issues after taking the shot .The withdraws were awful after stopping the drug. And I developed a hypothyroidism while on it then it went back to normal after going off shot. my last shot was suppose to be march of 2013 but I refused it. since then im still waiting for my period to return so that my body be restored back to its normal self. I HATE this b/c and will NEVER use it again. It may work for some but its not for me. Its poison!!! NOT a good drug! F 30 1 years
4 shots 1X O
9/17/2013
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Patient History
 1  Contraception Acne, oily skin & hair, vaginal dryness, night sweats, numbness/tingling in hands & arms when sleeping, swollen breasts, weight gain around the waist I got oily skin & acne from the start, assumed it would settle down but it never did. After the 5th injection the other side effects suddenly got a lot worse so I decided to stop taking depo. A year & a half after my last injection my periods are only now getting back to normal (I had them about every 2 weeks for 9 or 10 months). I also have swollen breasts & discomfort in my upper arms & legs due to swollen glands for the past 5 months. Thankfully the other side effects are gradually wearing off. Before I got my first injection I was told it could take "up to a year" for the depo to get out of my system, that my bone density could be affected through prolonged use & that my periods would most likely stop while taking it. I was not warned of any other possible side effcts. I've also had a sore throat that flares up every few weeks & leaves me feeling exhausted by evening; I don't know if it's connected to the depo but it started a few weeks after my first injection...the doctor says it's a low grade virus that my body has been unable to shake off. F 30 15 months
12/6/2009
 1  didn't want to get pregnant Been on depo and it's the worse experience. Head aches all the time. Sick every morning. Breast hurts. Lower back hurts. Mood swings really bad. Tired all the time. Got pregnant while on it the 1st time I was on it. Everyone use different birth control don't ever go on the depo shot!!! It's terrible on your body!! I'm never going back on it!!! F 30 2 months
7/25/2014
 1  painful periods Nurse gave me 2 shots in 2 weeks to try stop heavy bleeding. After i bled continuosly for nearly a year (previously my periods lasted around 7 days and were regular every month). iron was a daily thing afterwards to stop anaemia, dizzy, faint, feeling "not real" , panic attacks, breast cysyts, acne, severe weight loss and extreme agorapbobia, still struggling and fighting everyday to get my life back. I seriously never recommend it to anyone. Once its in yr system its in. I do think a lot of it is to do with individual hormone balances as some people it works ok for and others not,maybe if they had a way of testing everyones individual hormones they might see a pattern on who it wont agree with, but along with the bones loss-is it really worth it?! F 30 2 months
7/24/2014
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 1  painful periods I have been on depo for 2 weeks and since then i am having constant abdominal and leg cramps in fact my left side has been numb. I told my doc about what has been happening and she said the shot would not cause that but i know my body and i know the immediate changes since i started this thing. I am now depressed! Never again F 30 2 weeks
2
4/16/2015
 1  birth control weight gain, period for 3 months straight, moodiness, stomach issues, consitpation and diarrhea, some hair loss Ever since starting depo, I haven't been able to lose weight and I just pack on the pounds even though I'm active. I was on the shot for 2 years and just went off it almost 2 months ago. Since going off, my breasts have been tender and sore. I still am packing on the pounds. I still haven't seen my period yet and after reading about other's experiences, I don't expect my cycle to return to normal anytime soon. My husband and I want to try to have a baby but I'm terrified it'll take a year or more. I've been having bad headaches since going off the shot. While on the shot I wouldn't have a bowel movement for a week or more and then when I did have one, it would be diarrhea. It was awful. It was like this every week for 2 years. I just didn't realize it was the depo causing it until I got off of it. I wish I would have had the sense not to use this form of birth control. F 30 2 years
9/2/2009
 1  heay periods fibroids Mood swings, depression, nervousness, lack of motivation, could not sleep This is the worst ever. I am NEVER getting another shot. My gyn suggested that I take this to prevent heavy periods. This shot has had me scared for my life. I stopped working out and became very angry at times. F 30 2 months
11/17/2009
 1  Prevent pregnancy migraine, mood swings, mild hair loss, acne, increased appetite, long menstrual cycle I do not recommend this product. I took the shot in May and everything was fine until the end of June. At that time I started spotting continuously (every day all day) and then I had my cycle which I thought would fix this issue but it went on for 2 1/2 weeks and then the continuous spotting returned. I am now into my eigth week of my long cycle with no sign of it stopping. My doctor has told me this is a reaction that some women experience and I have to wait it out until the drug is out of my system. The information I have found suggests that this could continue for 6 to 8 months. So I would highly recommend another form of birth control first before using this method. You never know how your body will react to this shot. F 30 3 months
8/19/2009
 1  To prevent pregnancy at the time Of course the big "W" weight gain,I too experienced some major mood disorders I got this injection only once and wouldn't recommend this to anyone, got it in November, should have been out of my system by Feb.my periods still aren't regular and I can't get pregnant for some reason F 30 1 days
7/3/2009
 1  birth control/no more babies nausea for about 2 weeks, weird pains in stomach, chest pain, leg pain, depression, fatigue, insomnia, forever bleeding, weight loss about 8 pounds I started depo on february 2, 2009 and I was on my period. It stopped for about a week and then the spotting started. One night I had a constant left pain in my side and I was extremely nauseated. That went away. The bleeding continued and the 2 weeks later the constant nausea began. I lost about 8 pounds I was 138 now I'm a solid 130. The nausea has stopped and the bleeding has not. My chest pain and leg pain concerned the docs so they told me to go to the emergency room and I did. They did cat scan, chest x ray, ekg and all, they found nothing. I feel overall just bad. For some women its wonderful, but for me I wont be going for my next shot. F 30 2 months
4/7/2009
 1  contrception numbness in legs and arms pins and needles can hardly walk im 30 feel 90 dont use it i have had 2 shots and im like an old lady anyone had similar symptons please e mail me F 30 6 days
3/7/2009
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 1  birth control Anxiety, headache,themors,shakey, nausea, weak,tiredness This shot had ruined my life until it wears off... I regret getting it. Its poison F 30 2 weeks
9/3/2016
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 1  Birth control Fever, chills, body aches, headaches, breast pain, spotting Poison needle! I would wish the three months of side effects on anyone, my doctor told me it was like the pill! What a lie! F 30 3 months
9/22/2016
 1  contraception After I had the shot I felt completely fine, then two weeks later I started bleeding, my blood was brown and then at times it was bright red. The bleeding would stop for a few hours at a time then return, i got no restfrom it anf because i am anemic my health depleated drastically. I was always tired, I could not get enough sleep even though I was taking naps through out the day. My appetite greatly increased,my moods were eratic I was either crying or angry, I felt depressed all the time. And had intense lower back pain, it felt like a truck was on my back. I just didn't feel good I felt out of control of my body, like my body was my worst enemy and doing what I wanted it to do. Then came the acne. All in all this was my first time on the depo shot and it is my last. I would rather get pregnant then feel this way for the rest of my life. Depo has ruined my life, body and relationship. Its a terrible drug that should banned. F 30 1 weeks
2/25/2017
Email
 1  preventing pregnancy No period,and when they come it's either too little like spoting or alot and very painful periods,during the 1year I gained a lot of weight which Icant seem to loose,its been 2years since I stopped using depo and still my body has not gone back to normal Any one thinking of starting depo should think twice. F 30 1 years
00
5/18/2016
Email
 1  To not get pregnant The first time I took the shot it was great I felt happy and full of energy. The 2nd shot not so great. Have been tired and grumpy just finished a 13 day period. Yesterday started very bad heart palpitations every 2nd beat feels wrong. Went to doctor results are basically bad anxiety. Going to get a 2nd opinion as I think its definitely the shot. STAY AWAY PLEASE F 30 18 weeks
Shot
1/8/2020
Email
 1  birth control never had mental problems. since the shot i’ve had nothing but severe depression/ suicidal thoughts. i feel fine, but my mind is playing tricks on me. i’ve never been suicidal and i don’t even have a reason for feeling that way, life is great(normal). will never take it again f this birth control F 30 1 weeks
2/24/2020
Email
 1  Prevent pregnancy Headaches , loss of appetite, weight loss, muscle twitches, joint pain, dry eyes , depression, slight acne, stomach issues 2weeks after the depo I started having muscle twitches, it has now been almost 2 months and I am still having the twitches! When I first off the shot I cried all the time .. I lost 8 lbs in the first 3 weeks ! I wouldn't recommend this for anyone F 30 2 months
6/17/2020
Email
 5  Severe Cramps No Periods! Possible weight gain but I have always been heavy. I had extremely severe cramping before depo, I would lose 2-3 days every month curled up in bed with a hot water bottle and as much IB prophren as I could take. The pain was so severe that I sometimes passed out. The doctors tried various things and one finally decided that Depo might work and it was a life saver. I had one doctor do some research for me on the bone loss over long term use and he found that the risk is in a small percentage of the population. This drug isn't for everyone but for some of us it is all that will work. Do be careful and pay attention to your body. I had an ideal reaction and now that I have decided to go off it to get pregnant, I am having some of the side effects that most people had going into it. Moodiness, long periods, hot flashes. Unfortunately the cramps are back as well. F 31 7 years
9/24/2008
 5  Birth control; heavy periods no period, lack of sex drive I absolutely loved it! I took Depo for 5 years (starting when I was 21) and had no period the entire time. My fiance turned husband also loved the fact that we didn't have to use any other form of birth control. We decided that we wanted to have children when I was 26 and I stopped the shot; we started trying 12 months after my last shot and I was pregnant 2 months later. After my pregnancy was over and my periods returned, they were lighter and shorter than any I'd had before the depo (from 8 days of VERY HEAVY bleeding to 4-5 days, with only 2 days of heavy bleeding) and I could predict my periods down to the hour. This continued after my second pregnancy, as well. While I can't say for sure that it was the depo, I certainly can't complain. F 31 5 years
5/11/2009

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