DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  to stop all the bleeding After reading all the things that have happened to everybody I have to say the only bad thing I can say about it is it didn't stop my one day a month of cramping. Before the shot I could go months with none stop bleeding and im not talking light bleeding im talking so heavy you can feel it. Since taking the shot ive had my period of very very light bleeding im much happier now then I was my sex drive hasn't changed and I haven't gained weight in fact im still losing weight on my diet. My advice to anyone looking im to it there is risk with any drug you take so talk to your doctor. F 23 1 months
7/4/2013
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 4  very painful periods When I first started taking this, i was about 165-170 not very husky.. ive been on this for about 3 years and ive ballooned to a whopping 230 pounds. And on top of that I have a hernia. Doubt if the depo caused that but all this extra weight that im carrying around is hard to get rid of. I dont know. I dont recommend this to anyone but I am kinda satisfied because I havent had a period. I would like to switch but im not sure. F 23 3 days
1/16/2014
 4  prevent pregnancy Diarrhea, stomach cramps, gas I got this shot while not on my period. I have had no spotting and no period whatsoever so far. Every time I eat I do experience stomach problems, but they are tolerable. F 23 3 weeks
12/2/2014
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 3  Endo Breaking out, loss of sex drive, blood clots, Mood swings, very emotional, headaches, tired I am trying to stay out of surgery b/c this will be my 3rd one. I want to have kids at some point. F 23 6 days
3/20/2008
 3  It was the easiest solution Tremendous weight gain, headaches, decreased libido. I have been on depo for four years now. Four wonderful years without a period, but four years to gain 45 pounds. I am doing nothing different as far as my diet and/or activities, but since being on depo, I am 4 pants sizes larger and 45 pounds heavier. I love the convenience of this pill and the fact that I haven't had a period, but it isn't worth the side effects; most of all, the weight gain. I used to be a small 109 pounds in a size 2/3. Oh how I would love to see those days again. That is why I have finally decided to get off depo, and I will never, ever, ever use it again. F 23 4 years
2/8/2005
 3  prevent pregnancy great till i went off it I loved Depo while I was on it. I never had to worry about anything: pregnancy or periods. But now that I am off it I have been on my period for two months with no end in sight. I mean bleeding, cramps, mood swings, and depression. I hate it. My fiance and I fight all the time about it now. I feel miserable. F 23 3 years
4X O
4/10/2011
 3  birth control headaches, constantly tired, seriously moody, nauseated easily (even from video games on a led tv!), annoying weight gain, lots of hair loss, decreased libido and vaginal dicharge or whatever you wanna call it ... not good for sex when you actually do it! lots of acne, severly oily face and hair, spotty periods i didn't connect any of these side effects with the shot until recently. i went to the dr for my scary amount of hair loss and sleepiness and mood swings and was presscribed stress medicine soon after my second shot. after my third shot i gained 10 freaking pounds all in my midsection and legs (which is extremely noticeable on a 105 lb girl!!) and realized my sex drive was really low and finally my boyfriends sister put the dots together for me because she had read this stuff online. definitely won't get the next shot and now i'm worried about how long this crap is gonna take to get out of my system! i also had one random shot about 6 months before this set of shots and afterwards i found out i had poly-cystic ovary syndrome and supposedly its gonna be hard for me to get pregnant in the first place but not impossible which is why i got it again after the dr said to fix my irregular periods (which now makes no sense because the depo causes irregular periods any)... so now i'm freakin out that the depo caused my poly-cystic ovary syndrome after reading more reviews about this!! and my possible infertility!! F 23 9 months
1X O
8/25/2011
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 3  Birth Control Weight gain/loss of period/mild cramping/eczema on legs I went on Depo-Provera because I wasn't comfortable being on the pill. I'm terribly forgetful and figured this would be a great way to get contraception without having to take it every day. So far it's been 60 days. Right after my first injection I lost my period completely, which I'm honestly not complaining about. I've gained about 15lbs but I feel I could better control the weight gain if I really wanted to work at it. My only major complaint is the eczema on my legs. I started Depo-Provera in December so I attributed the itchy patches to dry skin caused by the weather. They haven't gotten better and it's starting to spread from my lower to my upper legs. While this is uncomfortable, I'm still not ready to wright Depo off completely. I'm giving it another three months and if I'm still scratchy or if I gain more weight, I'm switching to Ortho Tri Cyclin. F 23 60 days
1 shot 1X AN
3/17/2012
 3  to be protected from getting prego Um the depo for me is not bad def better than pills but the only downfall not to be to explicit is the spotting I have been spotting ever since alil after my first shot an it hasn't stopped since its annoyin...def makes me not feel comfortable at all in regards to sex an it jus sucks...the depo is a very good medicine but this side effect sucks. Also kind of hav a lost for appetite. Which sucks cause I am already skinny as it is...but other than that its an ok solution for bc jus watch the side effects..:) F 23 6 months
1X M
11/11/2010
 3  Dont like taking pills I didnt mind some of the affects, yes I hated the weight gain and some of the mood gains but I liked not bleeding every month cause I have always been a heavy bleeder. But the reason that I'm here typing is that I've heard that some women after using this method can't get pregnant. So I'm asking that the women here to please if you have experience this. F 23 2.5 years
idk 1X AN
10/1/2010
 3  Birth Control Weight Gain, Bone loss I gained 18 pounds on depo, wich is really hard to loose the weight. Normally I would just diet and my weight would go down, but diet and exercise isn't cutting it!! Also I just got a bone density test and it shows that I have osteopenia which is close to osteoporosis. Creepy!! Good thing about this no periods which decreased my migraines. F 23 3 years
1X AN
2/25/2010
 3  Birth Control Night sweats, hot flashes, boil/cyst like acne, lack of sex drive I got on the shot because I was really bad at remembering to take the pill every day. I spotted for about the first 6-8 months which was extremely annoying, then I stopped getting my period all together (not complaining). The side effects didnt start happening until about a year of taking it. I didnt gain any weight at all though, which i found surprising. It's almost as if it makes your body think it's going thru menopause. It served it's purpose, but the side effects arent worth it. I'm switching to Ortho-Tricyclen now. F 23 2 years
8/22/2006
 3  Avoid Pregnancy depression, loss of sex drive, mood swings, hot flashes, heart palpitations I was satified with what the drug is for. I didnt get pregnant but if I'd have known I was going to FEEL pregnant, I wouldnt have gotten the shot. My relationship with my fiance was greatly affected by me taking this because I was a constant bitch, didnt want to have sex, etc. F 23 3 months
9/26/2006
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 3  Birth control i was thinking about getting off the shot since the next one is due in about 10 days! i am curious about what other people have to say about it! i think it's great that i haven't had a period in 4 years but really how good can that be for your body? either way, about 3 months ago i was diagnosed with severe depression. I take my happy pills every day and they dont seem to be doing anything! after reading ALL of these posts i have come to realize that maybe my depression and everything that goes along with it could possibly be caused by depo! Oh the poor people around me that have to deal with this on a daily basis!!! I am looking for advice so please contact me via email if you have anything that might help...the good and the bad! thank you F 23 4 years
10/24/2006
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 3  Migraines with Pill NO SEX DRIVE At first, I thought this was the miracle drug from Heaven, no periods, no mood swings, little maintenance. Until my marriage started suffering from my absolute lack of sex drive. In fact, it's been over a YEAR since I can remember actually wanting to have sex, and I'm only 23!!! F 23 2 years
6/29/2004
 3  To regulate menstruation Weight gain, lethargy, worsened acne, increased depression, loss of lubrication and sex drive. I started taking depo because my periods were very heavy and painful, even on the pill, and often associated with migraines. Initially I had a lot of spotting but this was still preferable to my period, and then the bleeding stopped altogether. As long as I got my injections on schedule, I could prevent the spotting, and had no periods or migraines. However, I did have a history of depression before I started depo provera and this worsened the longer I stayed on it, and changed as well. I used to be a skinny insomniac who survived on the occasional candy bar and couldn't nap if my life depended on it... on depo, I gained close to 50 lbs and was so tired all the time I spent whole days sleeping, only getting up to eat. When I was awake I was cranky and irritable, and I lost all interest in sex, and even if I could dredge up the urge it was dry and painful. My teenage acne returned with a vengeance. At this point, I need to lose the weight and regain my old level of activity or I will very shortly become Type II diabetic, according to blood tests. I have decided to stop taking depo, and with the help of Weight Watchers I am already losing the weight. I am only spotting now, but I fear my horrible periods will return soon... I would still recommend depo provera to someone with very painful periods, but the depression (which also causes weight gain and loss of libido) whould be watched closely and treated if necessary. F 23 3 years
11/19/2004
 3  Birth control Breast tenderness, hot flashes, bones hurt and feel sick the day I get the shot, irritability, wanting to snap, recently (after 6 years) bled every 3 months until I got the shot again ,weight gain badly!!! Ive been on depo for 10 years never missed a shot other than a 6 month break 6 years ago and its just horrible I feel sick and my body hurts soo bad the day I get the shot I always feel on edge and moody and I absolutely hate it! The hot flashes are horrific had one this morning where I literally had to go outside and its november in michigan ... Always switching moods its all odd finally I told my fiance I'm done with it and November 4th was my last one and I promise I will never go on this roller coaster again!! Gained so much weight! Cant wait for this last shot to get out of my system!! Does NOT recommend F 23 10 years
1X O
11/20/2020
 2  Birth Control Multiple periods per month, frequent spotting, mood swings, fatigue, and lower back pain. I have mixed feeling about birth control & I don't know what to do. I was on the pill but it made me nauseous. There was a 4 month span where I was not in a relationship so I went off birth control, & I felt so much better! I got into anther relationship so I decided to try the shot, and I'm not nauseous, but I have my period or spotting almost all the time! I have not gained any weight, but I'm a Pilates instructor who eats a very healthy diet. I also have had lower back pain, and a lot of mood swings, but I can't be 100% sure if they are related. I do feel more tired when I have my period or spotting, which with the shot is most of the time. I'm supposed to get my second shot soon, and I don't want to but I'm afraid to rely on condoms alone! Any advice? F 23 3 months
1X AN
11/5/2012
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 2  Birth control Weight gain, headaches, body aches, severe mood swings, low sex drive I started getttig the shot when i was 17. It worked with noo side effeect for a year. I stopped getting the shot( broke up with my BF) I started it again when i was 21 it worked fine for a year but once I experienced my first anxiety attack right before my wedding I went totaly out of wack. I started gaining weight, crying uncontrolably, having horrible mirgaines that would lasdt for days, ot have weird shooting pains in my head. I had an MRI of my brain bc they were so often. I had no sex drive (being a newlywed this really upset my marriage) I stopped the shots in November 2010 and have not gotten my period yet. My doctor said that i might be three months after my last shot to get out of my system before I got my period. That was supposed to be February but nothing. Ive had alot of PMS symptoms off and on through out the entire time. The crying, severe moods swings, and really low sex drve have all kind of gone away but the migraines, fatigue, body aches still remain :( F 23 3 days
1X O
5/18/2011
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 2  Birth control Weight gain, depression, always tired, hard time getting pregnant after 5 years of taking it I loved not having a period for 5 years but, now that I am married and we want to start a family I am having a really hard time getting pregnant. If you are on depo and are thinking about having a baby anytime in the next year get off of it now. When I first got off of depo for the first 2 months you get all of the symptoms that you are pregnant. Morning sickness, tender breasts, all of that good stuff but believe me your not pregnant. I was on another web site and the average time it takes you to even get a regular period is almost 2 years. And it took most women that I talked to 3 or more years to get pregnant. I think that have a baby when you want far out weights having your period once a month. F 23 5 years
1/20/2005

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