PLAQUENIL Reviews

Average Rating: 3.2 (663 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Lupus After one yr. prickly burning skin on arms and legs. Pin like pain. Like sunburned skin F 57 1 years
200 2X D
7/4/2021
 1  no reason heart side effects, dizzy, blurred vision, lightheadedness, chest palpitations fast heart rate, high blood pressure, chest pain, left arm pain, everywhere pain, tingling, shortness of breath took this drug and it was horrible, been 35 days without taking it wondering how long i have to wait for sides to clear M 21 30 days
200mg 3X M
1/24/2021
Email
 2  LUPUS STE, SJOGRENS I was hopeful for this medication as it helped one of my close friends with Lupus. Within a week, I started to get very irritable and wanted to yell at the postman... this is nothing like my character. I also started to have a burning like sensation on my skin, like when you get a sunburn and go back out in the sun. My scalp started to burn and itch followed on the last day I took it - I started to get hives. I took claritin immediately and called my doctor. He said it stop it immediately... I had such high hopes for the joint pain and mobility with this drug, it was disappointing as I won't know if it would of worked for my pain. I just currently stay on 5mg of prednisone to help, but it isn't enough. F 44 1 weeks
200 mg 2X D
11/27/2020
Email
 4  Rheumatoid arthritis Took for RA. Had mild Psorisis before taking and understood it could make it worse. Well, it worked beautifully for RA. Loved this drug and got immediate relief from pain, and had so much more energy. Unfortunately, it caused Psorisis to form and spread rapidly all over. Wish I could have stayed on it. Would recommend for RA. F 57 2 weeks
1X D
10/10/2020
 2  Polyarthritis Eyes a little dimmer when reading - I have spoken to at least 3 Dr/ Specialists and have had Ross River fever some 20years ago - I took about 18 months to recover from ROss River fever ( which according to the world "you never ever really recover" as it is an immune response problem and I was treated with Feldene etc over 2-3 years - the Drs told me that I would have recurring "bouts of hectic pain" in the future accompanied by Malarial type reaction about twice a year - tiredness , exhaustion, and stiffness followed but I rowed my machine daily , ate good healthy food , few red wines and became pretty fit & well again / My previously damaged joints like toes ( football) and hands -fingers / wrists ( boxing etc ) have now erupted into a very painful state whicb varies in intensity day to day .... The Gurus label it - Polyarthritis - and its just 'wear & tear' and have suggested Methotrexate as a final solution but introduced me to every other pain relief like Diclofenac - Ibuprofen - Celloxocib - Paracetamol - and all of these in various generic presentations ? I sleep at night after Panadol x 2 but usually wake twice or so on the night with soreness and by 6am I am feeling exhausted - I am a reasonably robust person , I walk & swim comfortably but I am generally declining in my self - The pain ha at times in my wrists agonizing and I really don't know how to control or maintain at 76 4 weeks
20mg 2X D
9/27/2020
Email
 1  Dermatomyositis/ connective tissue After taking plaquenil about a week, I started itching all over my entire body. Noticed a severe rash. My skin felt hot to the touch. Went to dermatomyositis who said stop taking it and did a biopsy to confirm I was allergic to the drug. Nine days later and not any better. Back to dr who said it may take weeks to get out of my system. I'm rotating ice packs throughout my body. This is the worse nightmare of my life. Unbearable itching from my head to top of my legs keeping me awake all night... please let this end soon. F 81 8 days
200
6/24/2020
Email
 1  Rheumatoid Arthritis The first day I took it, I just didn't feel right. I had abdominal cramps and nausea. On the 4th day, I had had a severe headache for 3 days. That evening, I started wheezing, couldn't catch my breath, felt like a weight on my chest, rash on neck and face. I started taking benadryl and albuteral puffer because I couldn't breathe. I felt like I had a focal seizure. I finally got myself under control late that night. I didn't take it the next day, but I felt like I had the flu. I couldn't get out of bed. My eyes would barely open and felt like they were raw. I'm on my 4th day off of it and I'm just now feeling a little better. Still no energy and I'm having muscle shakes. I'm still having wheezing and hard time breathing. Also, on the few days I was on it, my BP and hear rate were high. I could hear my heart beat loud in my ears. Anyone else experience this? I have tried to get in touch with my Rheumatologist with no luck. I'm scared to try to take it anymore. F 47 4 days
400 mg a d
6/3/2020
Email
 3  Arthritis Had a bad rash on my legs back arms Taking plaquenil for 2 years or more for my arthritis it did help but side effects were reall bad my GP didn't know what the rash was i was treated for scabies for 5 weeks and nothing helped the rash it got so bad i ended up in A E for 17 hours doctors didn't know what it was after waiting for so long i got to se a consultant he couldn't make it out and said I needed to seen a dermatologist asap was sent for a biopsy and told it was a reaction to the plaquenil i stoped taking it there and then that was over 6 months ago still have some problems with my legs but my arms have cleared up went through hell scratching all over my body F 56 2 years
Not sure
5/18/2020
Email
 5  SLE & rheumatoid arthritis Loss of hair, irritable, nervous and recently sore eyes Overall has really helped my condition F 38 4 years
200mg
2/24/2020
 2  Lichen Planopilaris Dizziness and Fatigue Stopped it myself after 2 weeks due to it making the condition worse F 26 2 weeks
200mg
12/20/2019
 1  RA It’s one thing to be in chronic pain after being on this drug for about five or six weeks now and the only side effect I have is a bad one!!! it hasn’t helped my pain from rheumatoid oh but my hair is falling out ,isn’t that lovely! Besides being in pain I can look at how ugly I am now with all my hair falling it’s just a horrible way to feel,, specially being female to lose your hair and be in pain every day! RA sucks and so does all the medication that they come up with ,,were guinea pigs!! 😢😞 Can someone tell me if their hair loss stops or does it continue until you’re bald??? Also, my eye doctor is aghast that I’m on this medication seeing I’ve had many issues with my eyes!! 62 6 weeks
200
12/11/2019
Email
 3  Rheumatoid Arthritis Taking plaquenil gave me moderate relief from the joint pain. I only stopped taking it because my primary physician would not keep prescribing it; she insisted that I should see the rheumatologist regularly. I could no longer afford to see him or the other specialists I was seeing. The worst effect that I am aware of is the fact that my teeth have gotten progressively worse and keep breaking off at the gum line. I don't know whether it's the plaquenil or not, but my hair became really wavy and I had always had very straight hair before. F 61 2 years
200 mg bid
10/3/2019
Email
 4  Unknown Rash Had so many symptoms at the time. Couldn't tell if I had any side effects. Let's say, if it wasnt for me taking it. My rash would have invaded my entire body. What a terrible site I was. No more Cruises for Me... F 56 7 days
20mg
8/13/2019
Email
 1  Autoimmune flare My appendix ruptured. My doctor gave the credit for me surviving to God. PLAQUENIL is a synthetic Quinilone, belongs in the Floro Quinilone family which has a black box warning by the FDA. I did not this at the time i took it. Previously had bad tendon damage with Cipro. F 66 15 days
2- 200mg
8/6/2019
Email
 4  Lupus First month 400mg/ day, main side effect was diarrhea. Second month I realized I was becoming very photosensitive and even minutes of being exposed to sunshine I would burn in large spots. I was also experiencing very strong tingling in hands, feet and lower limbs. It was like little misfires or little shocks everywhere. Was given steroid pack. Tingling somewhat subsided but not fully. 8 months in we went to Florida for vacation in spring(from Canada). Within days the peripheral neuropathy kicked into overdrive, I was not only tingling like crazy but now I was going numb, fatigued and even disoriented. Called my dr back home. He lowered my dose to 200mg/day in evening. I leveled out very quickly (couple days)and symptoms became less severe. Fast forward 4 more months, peripheral neuropathy was getting worse even on lower dose and fingers and toes were also aching now, constantly tingling and numbness would come and go. All blood work came back "normal", lupus is in remission/ inactive. Yay! Dr stopped Hydroxychloroquine (plaquenil) yesterday fearing it is now doing more harm than good. Over all I do feel it may have caused increased anxiety and depression and irritability...however lupus alone can trigger those symptoms I'm sure. Overall Plaquenil did take away the muscle and joint pain. It worked wonders for that. For that reason I am satisfied with plaquenil for what I took it for. Took about 5-6 months to see full effect. Since reducing the dose from 400mg to 200mg 4 months ago I do feel some of this pain returning 🙁 You win some, you lose some! M 49 1 years
400mg day
7/25/2019
Email
 1  lupus Plaquenil can make you completely blind! *Legitimate looking vitamins I take to help remediate it I took Plaquenil for over 13 years and it caused me (and 6 in every 1000 patients, new research shows) to have toxic maculopathy it caused. *re: even if you quit taking the drug, it can continue to damage the eye until blindness occurs. If you are taking it, make sure your physician is using the NEW guidelines on treatment ==I think it is no more than 5 milligrams per kilogram (For example just heard an example on this video if under 140 pounds you shouldn’t be on 400 miligrams —https://www.youtube.com/watch?v=D35uZA-vjPY ) Friends: If you have ANY changes in your vision, friends, head to a retinal specialist--1 test I had an angiogram done. My first retina specialist said i could be blind in 20 years without telling me the odds of that happening or giving me hope My 2nd retina specialist doctor thinks that, since I have had very little deterioration since stopping the drug 18 months ago, I may be one of the fortunate ones that only have some damage. All I thought Plaquenil could do to my eyes was to cause them to lose color vision. I never truly understand what the Humphrey Visual Field Test was (and it is very rudimentary, my current retina specialist doctor said. If you have ANY changes on this test, be accessed by to a retinal specialist It did work well to make my Lupus/Scleroderma is more symptomatic Are there any support groups or experimental therapies for toxic maculopathy? *I am looking for experimental treatments or for information sharing on this! +++++++++++++++ I found EyePromise Restore Vitamins that I take for retina health== those particular vitamins seems highly rated on all websites and that my retina specialist recommends —they are backed by 2 studies cited on their website called the Ares studies *Website for vitamins: www.eyepromise.com I take these eye vitamins I take to remediate future damage beyond what Plaquenil has done to my retina/macula (I have toxic maculopathy) I researched them thoroughly and they seem very legitimate. I am not paid and do not have any interest in selling EyePromise fyi! F 51
1X D
1/12/2019
Email
 3  possible lupus At 100mg/day I am already feeling less joint pain and wake up with more energy. This has been a tremendous relief after several years of chronic inflammation and exhaustion. That said, my doctor had originally prescribed for me to take 100mg/day for one week and then increase to 200mg/day. When I increased to 200mg/day, I had strange side effects that caused me to go back to 100/day. Strange leg cramping, restless leg, nausea and anxiety. In a nutshell, at 200mg/day the side effects outweighed the benefits. At 100mg/day, I do not have 100% reduction in my symptoms, but I have enough of a reduction to want to continue the medication. F 40 2 months
100 1X D
10/23/2018
 3  Lupus Tachycardia up to 180 bpm ,and hair loss My joint pain is much better F 64 7 months
5 mg
10/21/2018
Email
 2  Possible Rheumatoid Arthritis Severe depression and anxiety, overall itching, pain and stiffness increased instead of decreased First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. When I started taking Plaquenil, I got a bit depressed but that's not a big deal. It is now 6 weeks later, I've titrated up to 600mg. per day, and I am SEVERELY depressed, to the point I can't get out of bed some days. I am sicker mentally than I have been for 16 years, and it didn't start until I started the plaquenil. I'm so anxious, I'm agoraphobic and having anger attacks. I have never been agoraphobic in my life. Yes, I have bipolar disorder but it is well treated, and these symptoms did not come out of nowhere. They date right to when I started taking Plaquenil. I see my doc in 5 days and rather than do the full 800mg., I'm weaning myself off, before I become suicidal (I already want to hurt myself, I'm so depressed, but not suicidal yet). I would recommend Plaquenil for people without or with only mild depressive disorders, but not to someone like me with severe, disabling bipolar disorder. It is downright dangerous to take that risk. F 47 6 weeks
200mg. 2X D
3/31/2018
 2  Possible Rheumatoid Arthritis Severe depression and anxiety, overall itching, pain and stiffness increased instead of decreased First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. When I started taking Plaquenil, I got a bit depressed but that's not a big deal. It is now 6 weeks later, I've titrated up to 600mg. per day, and I am SEVERELY depressed, to the point I can't get out of bed some days. I am sicker mentally than I have been for 16 years, and it didn't start until I started the plaquenil. I'm so anxious, I'm agoraphobic and having anger attacks. I have never been agoraphobic in my life. Yes, I have bipolar disorder but it is well treated, and these symptoms did not come out of nowhere. They date right to when I started taking Plaquenil. I see my doc in 5 days and rather than do the full 800mg., I'm weaning myself off, before I become suicidal (I already want to hurt myself, I'm so depressed, but not suicidal yet). I would recommend Plaquenil for people without or with only mild depressive disorders, but not to someone like me with severe, disabling bipolar disorder. It is downright dangerous to take that risk. F 47 6 weeks
200mg. 2X D
3/31/2018
  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.   (Sources: U.S. Centers for Medicare Services, FDA)

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