PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  psoriatic arthritis Extreme painful itching. This was especially severe after a shower. I had to stop the medication This was highly effective on my arthritis. But, the itching was worse than the arthritis. M 44 4 months
10/14/2005
 5  Mild Lupus with Sjogren's first few days i had stomach cramps. if i miss a dose for more than two days (only happened twice on vacation) i will have the cramps all over again. i have increased pigmentation on my face - my boyfriend thinks they are normal freckles but i think it's from the plaquenil. i consider this drug a real life saver for me. it started working around 4 or 5 weeks after starting on 200mg once a day. took carer of my plaque-type rash on upper arms, back, face and significantly improved my energy levels which were very low. pain overall decreased significantly and hair loss too. mouth dryness improved though not as much as other symptoms. fevers also lessened. in the summer however, i found i needed to increase dosage to 400mg one day and 200mg alternate days. this seemed to do the trick. i have eye exams every six months but am still concerned about possible problems here as i already have poor vision. I have concerns about getting pregnant on my current dosage and wish i could get more clear info -- my doc says it's ok, but the internet says different. F 41 4 years
10/4/2005
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 3  RA,, AVN HIP DISEASE , SJOGRENS SOMEWHAT BLURRING OF SIGHT (AT DISTANCE), INCREASED TIREDNESS, SOME DEGREE OF BRUISING WITHOUT REASON (NOT DUE TO ANY INJURY) NOTICE FEW FLOATERS, DARKENING OF SKIN (LIKE SUNTAN), MORNING PUFFINESS AROUND EYES, SLIGHT HEADACHES HAS HELPED PAIN (IN A LITTLE AS 3 WEEKS I NOTICED DIFFERENCE) @ 400/DAY. F 60 5 weeks
10/2/2005
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 5  Livedoid Vasculitis None Started healing very painful ulcers on my feet & ankles almost immediately. F 34 2 months
9/14/2005
 2  SJOGRENS SYNDROME The first time I took Plaquenil, at the one month mark of 400 mg daily, I came down with a very high fever, headache, shoulder and hip pain,nausea, anorexia, diarrhea and abdominal pain. I don't think I have ever been that sick before. I ended up in the hospital for many tests, all of which were negative, (no it wasn't influenza) so stopped the Plaquenil. After missing the first dose, some of my symptoms immediately began to lessen. I had been off it for about 4 months and decided to try it again just to be sure it was the med I was reacting to. Also, I did not like the next med step. I have been on it about a month in increasing dosages and am now again beginning to experience dizziness, problems focusing and slight nausea. I am going to see about lowering dosage to 300 mg per day (I seemed to do ok on that)before things get really bad again. The gas is horrible all the time, right from day one. I am not sure I have seen a decrease in any of the symptoms and wonder sometimes why I take it. I guess I just need to ask more questions of the Doc. M 57 1 months
9/9/2005
 1  Rheumatiod Athritis I had itching, rash,hives in my throat,blisters and burnt skin all over body after being on for 3 months but it took a month of that for the doctors to figure out that I had Steven Johnson Syndrome from it. I could barely function from moment to moment. When I drove anyplace I held on to the meds I was taking, my doctors names and numbers. Plus how to reach my husband and kids. If an emergency room doctor hadn't been on the ball I know that I would be dead now. As with any medication if you have reactions, stop taking it and investigate and demand someone helps you. F 47 3 months
9/4/2005
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 1  lupus-rhumatoid-MCTD-&scleroderma I'm 61 Have had these problems from birth & so do 2 sisters. In all such diseases the organs are attacked with no warning. While on Plaq.,I now have had diarrhea for 1mo.My vision is blurred and failing. My liver has enlarged. There is much more to be said but space will not allow. Why are we taking something that works the same as our diseases except we have less joint and muscle pain? I have been on steroids for 13 yrs.The problems show up when I'm on Plaq. I'm getting off again and will never swallow another one. Your organs can only stand so much, and the disease needs no help. I think prednisone is a safer approach. It makes you fat. Plaq. doesn't. For some this may be a problem. I've been sick long enough to accept it. F 61 30 days
9/2/2005
 1  RA Twitching, muscle loss, peripheral neuropathy symptoms. My rheumatologist said that he hasn't ever seen a worse reaction to this drug. It took six weeks to work, worked like a miracle for one month, but then it F 46 7 months
8/26/2005
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 3  RA very dry eyes,blurred vision occassionally, also,bad rash on foot,skin ripping,blistering,itchy all the time.now experiencing headaches an hour after taking med. remember to take after eating a good meal!this helps the nausea. At the moment I am experiencing bad flare ups.Have been on Plaquenil for approx 2 years now.I am constantly tired, but this is part of the disease anyway.Its difficult to say if the drug is F 43 2 years
8/24/2005
 5  mctd some stomach upset first few days, but may not have been due to Plaquenil I was on Plaquenil for a year and a half after being diagnosed with mixed connective tissue disease at age 30. It worked so well that I almost forgot I had the disease. I went off Plaquenil when I became pregnant last year, and was off for 14 months. During pregnancy my symptoms were muted, and I was able to get along with no medication. About 4 months post-partum my symptoms came back with a vengeance: swelling hands, joint pain, general aching. After two weeks back on Plaquenil (and I realize it takes up to six weeks or more to work fully) I have a significant decrease in swelling of hands--and the pain is much less severe--on some days almost nonexistent. I hope things continue to improve, but already my condition is so much better. F 33 2 weeks
8/12/2005
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 5  RA Small amount of gas, lack of appetite (which is not a bad thing!). I was on Plaquenil for about four years until I decided to wean off of it. It's been about 5 weeks now and I'm getting all these weird symptoms: a cold sweaty nose, a lot of bloating and gas, canker sores, small non-pimply bumps on my body and weight gain. I didn't realize how good I had it while taking Plaquenil! I'm still going to wait to see what happens. If I'm lucky, these symptoms will go away and the pain is still gone. Wish me luck! F 36 4 years
8/11/2005
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 4  Palendromic Rhuematism I do not notice any side effects specific to the plaquenil. I do have some hair loss but not enough to make me bald. I have a periodic rash on my upper legs that looks almost like shingles. I sweat profusely! I have a cast iron stomach so am lucky there. And I don't think I have any gas problems more than the usual person. With my disease being so rare and with so little info out there about it, I'm not sure what is to be credited to medication and what is from the disease. It took almost 7 months for the full effects of the plaquenil to kick in. I take 200mg in AM and PM. It has made a significant difference in my life. I'm not cured, but I can tolerate the pain now. F 44 20 months
8/4/2005
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 3  ? SLE GAS and bloating, every day, are my biggest problem with this drug. This is making me so uncomfortable I hope to discontinue this when I see my Rheumatologist in 2 weeks. My morning stiffness and joint pain have been almost completely gone since this med. started to work. F 43 5 months
7/29/2005
 4  Rheumatoid arthritis I have experienced the dry eyes. It comes and goes. Sometimes it really bothers me and so I just make sure I have Visine tears on hand. I store them in the fridge so they're nice and cool. The Opthamologist I see gave me some special drops but I prefer Visine Tears. Just be careful, I hear using drops can be addictive. overall I have found the drug to really help in my case. F 35 4 years
7/23/2005
 2  Lupus I only was on Plaquenil (200 mg. once a day) for a few days and then started experiencing the itching, then wheezing, then a rash on the trunk and upper extremeties of my body....called Doc. and said I may have an allergic reaction. Stopped taking it after two weeks. I don't really know if it helped or not. Still itching....anybody got any remedy for that?????? F 47 2 weeks
7/19/2005
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 4  inflammatory Arthritis etc. I believe my stomach aid and some nausea were some side effects, and dizziness. I have only taken for a short tiem now, but my knee and joints are already feeling much better, so it has helped. F 62
7/5/2005
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 3  Lupus like symptoms in hands., The medication helped my Raynauds symptoms and reduced the redness and swelling in my hands. I was taking it with an anti-inflammatory, Sulinac and 5 mg of Prednisone every 2 days for 5 weeks and broke out in a rash all over my body. They upped my prednisone to 30 mg and after 5 days I am still waiting for my rash to disappear. The medication seemed to help and my doctor wants to put me back on it after the rash disappears. M 49 5 days
6/29/2005
 2  Lupus Nausea, headache, irritability, very down or depressed, loss of what energy I had. I've been on it a month now and so far nothing positive. I haven't felt any relief from my pain. But the doctor said it could take up to two months to notice a difference. So I am waiting to see. F 33 30 days
6/16/2005
 5  Systemic Lupus Gas, diarrhea when first starting drug (or restarting drug after missed doses, etc.) Wow... for years, I did everything imaginable for my oral ulcers. Now, as long as I take my pill twice a day, I just don't get them. Had no official diagnosis at first because bloodwork results were subtle. Rheumatologist tried putting me on Plaquenil to check for response. It's been miraculous! I feel great! When I told her that if I miss even one dose it throws me off for about a week (one missed dose earns me a very painful oral ulcer in the next week or two... takes quite awhile to heal) she seemed very interested. When the insurance demanded a diagnosis, she diagnosed my Lupus. I fear missing even one pill because of my terrible oral ulcers (and that fear increases stress if I do miss a pill thus making flares more likely). Anyone else have reactions to missing one dose (or bad oral ulcers)? What do you do? F 27 5 months
6/15/2005
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 4  possible ra none, a little gas the first few days still have lots of stiffness in my hand and middle finger, but I am not so tired and dragged out any more, sleep a little better at night. But I am still a little apprehensive if there will be side effect the longer I am on this. F 55 24 days
6/7/2005
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