PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  UCTD Nausea, had to take at bedtime so this s/e would wear off.. Optometrists don't take eye problem potential seriously saying that doesnt happen nowadays. Quit taking it. F 54 4 years
200mg
1/23/2012
 1  Systemic Lupus Bulls-eye retinopathy in both eyes, despite at least once-yearly checks, when I got blurry spots doctors dismissed it at 1st, until my retinas were permanently damaged. I have ring shape blurry/blind spots in both eyes, right worse than left. The plaquenil helped with the lupus symptoms for the ten years I took it but you MUST be EXTREMELY VIGILANT about the eye problems and if you get any vision issue at all, go get checked immediately and do not let them dismiss your symptoms. The damage to my eyes is now irreversible and may continue to get worse. F 38 10 years
200 mg 2X day
1/20/2012
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 5  RA and Sjogrens In the beginning I had the stomach pain but my doctor ordered Omeprazole and I have not had any problem since. I will get itchy at times. I also take Ibuprofen 400mg TID, Tramdol 100mg about every 4 hours, Vitamin D supplement. It changed my life. I was in bad pain for about 8 years before this. It took a little while for meds to kick in (3 months). I lost 40 pounds ( but that was good) I was overweight. I take my meds regular and on time. If I get off schedule it does not work as well. At bedtime, I take 100mg of Tramadol, 800mg Ibuprofen and I sleep like a baby. I take the Plaquenil 200mg in the morning. Take at the same time every day and keep schedule. Be patient and give it time, it is worth it. Check eyes yearly. Get doctor to give meds for stomach pain. F 53 3 years
200mg 1X day
1/18/2012
 4  Rheumatoid Arthritis; Fibromyalgia Diarrhea that lasted about a week; flatulence that was very bad for the first two weeks, then tapered off and now is infrequent, but uncontrolable; headache when first taken each day starting the second day for a week; stomach cramping; I was told up front from my Rheumatologist that Plaquenil caused stomach cramping and bowel issues in the majority of the patients tested, so I was aware of it when I started it. I was also told it could take up to three months to start working. I was in so much pain that I was willing to give it that amount of time if I would be at least partially pain free after the three months. Luckily it started working within the first week, which I deemed worth the side effects I was having so long as they went way by the fourth week. They did, I don't have the headaches or nausea now. I do have uncontrolable flatulence which can be unpleasant in social situations but is mostly silent and non odorous. My pain is quite a bit less, I do still have flare ups and achiness when I squat, stand, sit or walk for long periods of time. My morning stiffness is lessened as well. Each person is affected differently by medications, so you have to choose if the side effects are worth the outcome of the medication overall. For me they were, but I understand many people do not like this drug and will tell others to not use it. If you have mild to moderate side effects, I would suggest giving it a few weeks to see if there are benefits to taking it before you try another medication. F 29 3 months
200 2X day
1/14/2012
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 4  Lupus Nothing other than Nausea when I don't take it with food F 29 1 years
1/10/2012
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 3  Rheumatoid Arthritis I just started this medication yesterday and my 1st dose my lips felt funny and I got this metallic taste in my mouth. Then during the night my instestines felt gurgly . Today was my 2nd dose and I got the taste again in my mouth again. Then I just felt loopy and I am not sure why that is. I am going to stick with it and see what happens and hopefully it will help me and the side effects will go away. I am super scared about the eye side effects. This seems like a very dangerous drug and I am making sure that I pay attention to all of my side effects. Oh, I also got a sore throat after taking these 2 doses. Anyone else ever get a sore throat after taking it? Weird for sure!! F 42 2 days
200 2X day
1/9/2012
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 5  UCTD vivid dreams, nausea F 31 7 years
400mg/day
12/8/2011
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 4  Rheumotoid Arthritis Plaquenil means instant nausea for me but I have learned to time it about 15-30 minutes after a good size meal to lessen the feeling. In month 2 the migraines kicked in completely out of the blue and put me on my ass. But I feel enough relief from the RA that the migraines are almost worth it. Now I'm just waiting for my stomach to revolt from the Excedrine and coffee cocktail I take to get rid of the headaches. Still Plaquenil is worth it to me. It's side effects pale in comparison to prednisone withdrawl or RA pain. F 37 3 months
400 daily
12/3/2011
 5  MCTD/ borderline Lupus It took 8 months of feeling horrible with the most random pains ( chest pain, ovaries pain, GERD) before it started working for me. Once it did work I was feeling great. If I feel under the weather I take x2 daily for a couple of days and it does the job. Patience is key, I say give it a try! F 36 2 years
200 mg
11/30/2011
 1  MCTD Symptoms started with a sore throat and general overall flu-like symptoms and then a horribly itchy red rash all over my torso, back, arms, thighs, and butt. Never felt well while taking them - acutally worse than my regular disease symptoms. The steriods prescribed to clear up the rash made me feel GREAT - the best I'd felt in years. F 39 21 days
200 2X day
11/3/2011
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 1  arthritis After 14 days-sore throat,headaches, diahorrea,rash on torso,arms & thighs;muscle twiching at night; relieved arthritis pain but side effects too unpleasant F 53 21 days
200 1X day
10/31/2011
 4  lupus nausea (if not taken with food) My pain and fatigue have been significantly reduced since I started on Plaquenil. F 21 9 months
200 2X day
10/30/2011
 3  Lupus, pain in joints and feet First week I was so sick to my stomach I cried...and I'm tough! Bad gas, terrible cramping and still trying to work everyday, killer! Suddenly, after week one my stomach feels better. I am still taking prednisone, which had massively reduced my pain already, really have not noticed any other relief, in fact this week has been a little worse. I guess that is just a bit of a flare though because I doubt the plaquenil could be built up enough to sort things. Just wanted to comment that the stomach torture improved, so if you exp. that, keep going. Maybe we too will feel the miracle others have described! Just scared when he takes the prednisone away the plaquenil won't be enough but I'll check back in for sure! F 48 9 days
200 mg 2X day
10/30/2011
 1   have lupus I am worse than when I started takink plaquenil why is it being sold to help persons with lupus when it is not helping? F 60 360 days
200 mg 2X day
10/29/2011
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 5  Rheumatoid Arthritis, Fibromyalgia Occasional nausea and lethargy. No biggy. Plaquenil has changed my life - I no longer stagger to my feet in the mornings and have to hold on to furniture to get around for the first 3 hours of the day. This is a vast improvement on my quality of life, and my nightly leg cramps have ceased. F 48 18 months
200 mg 2X day
10/25/2011
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 5  MCTD Initially a little stomach cramping and felt spacy on 2nd day. Since then no side effects. Suddenly felt like a new person 2 months after starting the drug. No pain, increased energy and don't need to go to bed at 8pm anymore. Feeling wonderful again! F 42 3 months
200mg 2X day
10/24/2011
 2  SLE, suspected RA & Sjogrens Stomach cramping, diarrhea, mild to severe headaches, dizziness, bloating, gas, loss of appetite and nausea. After having a terrible 4yr battle with debilitating fatigue, joint pain, muscle weekness, neuropathy, you name it and I suffered from it, I finally found a doctor whom discovered I was positive for certain antibodies and suspected that I had Lupus. I later became pregnant with my son and I was terrified knowing the condition of my health... The further along I became, the better I felt as odd as it sounds. It seemed that my sickness went into remission. I had my energy back and my body didnt hurt half as bad. It was great. My son was born 5wks early and the hospital encouraged me to breastfeed. I still felt better while nursing until I stopped producing milk after about 6wks and all of my symptoms came back tenfold. Obviously there must have been certain horomones that played a role in my remission. I was baffled. I was referred to a Rheumatologist a few wks ago and he ordered another blood test. My blood results showed the presence of antibodies ( ANA, Histone autoabs, U1RNP autoabs, Rheum abs). Amongst other findings my neutrofils where low, lymphocytes where high, and eosinofils where high. Also, the tourniquet was left on my arm the entire time and thats usually a no no when checking blood for certain things because it can cause inaccurate results. He said little about my results other than diagnosing lupus. I have had alot of symptoms of Sjogrens syndrome as well and severe dry skin all over, dry mouth, and dry eyes are just to name a few. I was eager to start whatever F 26 10 days
200MG 2X day
10/20/2011
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 2  utcd F 53 25 days
200 mg 1X day
10/8/2011
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Patient History
 5  Lupus I have experienced basically no side effects from it. Though, I have noticed that I have more gas. I didn't think to equate this to Plaquenil, but after reading some posts, maybe it's the reason. I was diagnosed with Lupus, and my main symptom was a low platelet count, and that has started to rise. As far as I can tell, it works great! F 25 10 months
200 2X day
10/7/2011
 3  UCTD Diarrhea,gas,nausea and bloating. Big mistake...Got off Plaquenil and have been experiencing horrible symptoms of fatigue and pain. Unable to work for the past few month.Got back on it about six weeks ago and still waiting for it to kick in. Won't go off it again if it starts working like it did before! F 54 45 days
400 1X day
10/5/2011
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