PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  RA/possible lupus Migraine, vivid frightening dreams, panic attacks, diarrhea, ringing in right ear, weight loss I have been on for about a month and a half, just recently I started to get migraines followed by panic attacks(haven't had in over 3 years). I'm hoping they go away! This drug has worked miracles for me, I'm holding out the panic attacks dissipate and I can continue or I may have to stop taking plaquenil F 31 45 days
3/18/2009
 5  SLE I saw no improvement to extreme fatigue, weakness, body aches, headaches, joint pain until about 5 months after taking Plaquenil. Dose of 400mg a day. I too, tried to discontinue this drug and after 3 weeks I could not get out of bed. My original symptoms were back and felt worse because I had lived without them for several years. Please be very careful with the eye exams. I had some brief episodes of blindness and more indepth testing was done (ERG) and this detected Plaquenil toxicity. I am told it has progressed to 'irreversible' state. If caught before any symptoms can be reversible for most patients. I was very diligent in getting eye exams every 6 months. F 52 15 years
3/17/2009
 4  SLE Lupus Some gas, indigetion, and blurred vision, thinning of hair. Many of the reviews report some kind of stomach distress, I can say that taking a probiotic daily has me helped huge. However after taking plaquenil for nine years I am considering getting off, due to the fact over the last couple years I have more tremors in my hands, more hair thinning and now wondering if plaquenil can affect your bones negatively. I am experiencing more low back pain. Also interrupted sleep. More blurred vision than in the past and more muscle pain. I get the eye exam each year. My doctor tells me, my low white blood cell count is due to the plaquenil. I will pray about what to do. I certainly do not want a flare. It seems the negatives of plaquenil are out weighting the positives. F 60 9 years
3/14/2009
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 4  i have lupus None F 44 6 months
3/14/2009
 2  Yes I was taking the generic Plaquenil 200mg per day. It upset my stomach so I stopped after 8 weeks. My doctor wants me to start the Brand name. Its been two weeks and I feel much worse after I stopped the drug then before I ever took it. My upset stomach will not go away, I feel lightheaded and am very tired. I did not have these symptoms before I started on this drug. I think it really messed up my body. I was told I have Sjogrens. Very frustrated at this point... M 57 8 weeks
3/14/2009
 5  UCTD with lupus like symptoms A bit of insomnia. I counteract this side effect with amitriptyline. A little gas the first week. The constant chronic pain has been dulled considerably and I'm only three weeks in. Morning stiffness if almost virtually gone. Hair loss was pre-plaquenil and this has not subsided (yet). Thinking seems clearer. I have to say I absolutely love this drug. If it does increase the hair loss that I had already before taking it...I'll wear a wig. It's worth it in comparison to the chronic pain without plaquenil. F 34 3 weeks
3/10/2009
 2  SLE & Hughes A couple of bouts of diarrhea initially, but have continued to feel nauseous and have brain freeze daily which flares with pain. It also seems to have intensified menopausal hot flushes/night sweats as well as mood swings = suicidal thoughts. At times I feel extremely cold. I feel mental and physical fatigue = lots of word searching, stuttering and sofa days. Last few days tip of tongue and lips feel numb. My GP contacted the Lupus unit, as she said that it was the worst she'd seen me in ages, and was told that how I'm feeling isn't down to plaquenil but lupus. They don't see Plaquenil as the cause but the cure. I don't know what to do for the best: endure or give up. Will see GP in 3 days to discuss. F 44 2 months
3/3/2009
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 1  MCTD For 6 weeks now I have had a rash all over my body. It seems to be fading everywhere but my legs. I have facial and ankle swelling. SEVERE INTENSE ITCHING. I am going crazy and feel like I will NEVER get back to normal. I would love to hear from anyone who has had a similar reaction. F 54 18 days
2/28/2009
 3  unknown diagnosis Stomach pains, nausea ( mild to moderate most days) instestinal issues, nightmares Overall I believe this is helping. My morning aches and pains are not better, my evening pains are much better. My 'needle pains' through out my body have been much less severe and happening less often. Today my doctor says to give it a few more months. She sounded please with the results so far. F 39 2 months
2/27/2009
 5  MCTD (Lupus and RA) during the first 2-3 months, I experienced red bumps all over back (fading, but still there at 4 months), nausea, diarrhea, headaches, bruising, restlessness at night, tiredness (probably from lack of good sleep). Most symptoms subsided after first 2-3 months. Could see the good effects from Plaquenil after about 3 months; My joints and energy-level feel better than they have in several years. For me this is definitely worth going through the 2-3 months of side effects. I still have some red bumps on back, but they have faded a great deal. F 23 4 months
2/25/2009
 5  Lupus Minor stomach upset the first few weeks, some gas, ringing in the ears, some hair loss but have had major benefits on this med. I've been on plaquenil for 20 years. I see an eye specialist 2x a year. Have never had a problem. I'm on 200mg once daily, taken right after breakfast. My Lupus symptoms have pretty much disappeared while on this med. I still feel some fatigue. Before plaquenil, I could barely function and could not work, had major pain and fatigue. Tried going off my med once to see how I felt. After 3 weeks, I went back on as I felt horrible. Will never try that again! F 52 20 years
2/25/2009
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 3  lupus within 2 hours of taking the medication, I experienced diarrhea/bloating/gas pain/flatulence. F 38 1 days
2/25/2009
 1  Sjogren's extreme dry eyes, seeing flashing lights, fatigue, possible weight gain I have been taking this about 1 month for peripheral neuropathy and Sjorgren's syndrome. My dry eye problem has gotten much worse since then - constant burning and lots of goopiness. I have incidents of seeing flashing lights about once a week. I'm also feeling very fatigued. I am a regular exerciser (5 days a week) but have had to cut back my work-outs for lack of energy. That may explain the mild weight gain, or it could be another side effect of the plaquenil. I'm going to stop taking it today and see if things improve. My doctors don't believe any of these problems are from the medication, even though they all started about a week after beginning the medication. F 50 30 days
2/25/2009
 5  Lupus After one week, started having increased anxiety, racing heart, back pain and panic attacks about 2 hours after taking pill. Doctors said Plaquenil doesn't cause those side effects so I stopped taking it and all side effects went away. (Was taking 400 mg per day) Started again a week later after all the lupus pain returned at 50mg per day. Cut the 200 mg pill into 4 pieces and take one piece in the morning with breakfast. Works great! No side effects and the arthritis pain, ulcers and rash of lupus are gone too. Maybe some people are really sensitive to it and need a very small dose. F 34 2 months
2/20/2009
 5  RA I haven't had any side effects at all, and I have been taking Plaquenil for 1 1/2 years. It's been very helpful with the pain, which was QUTIE severe when I started taking this, and the pain subsided within 3 weeks of taking it and I still haven't had any flare-ups except for when I occasionally have missed some doses. F 44 1.5 years
2/17/2009
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 4  Sjogren's Syndrome Nausea, Diarrhea, Mood swings, Crying for no reason, Bloating and Hot flashes. Even though Plaquenil has caused these minor (in my case) side effects, I feel blessed not to have to deal with the severe chest pain and fatigue associated with Sjogren's any longer!!! F 21 3 months
2/16/2009
 4  JRA rash on palms of hands, yeast infection I must be the only person who got the prickly rash on the palms of my hands! This rash seems to come and go throughout the day. It can be itchy at times, sometimes just red bumps. I have felt so much better in the three short weeks of starting this med, I think I will deal with the rash...unless it spreads. I got my first yeast infection, however, and that's not as easy to live with! I finally feel like myself again. F 32 3 weeks
2/13/2009
 4  Relapsing Polychondritis Nausea for the first couple of days, some hair loss, some minor chest pains. It gave me back energy pretty much immediately. After 2 years I thought I could go off it, and after I had stopped the medication for about 3 months, I completely "crashed", I thought I was going to die! I had the worst flare of my life. So now I am back on. F 31 2 years
2/12/2009
 1  Psoriatic Arthiritis Hearing voices in my sleep calling my name, which wake me up. Taken 2x 200mg per day with 6x 2.5mg Methotrexate 1x per week M 50 1 months
2/6/2009
 1  JRS uncontrollable muscle twitches that have remained for years, permanent nerve damage I went to the ER with uncontrollable muscle movements a couple years ago. My doctor said it was the plaquenil. My fingers still twitch, but not as badly since I stopped the medicine. I had also had caffiene during the inital twitching episode. F 17
2/6/2009

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