PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Rheumatoid Arthritis Initial hair loss (stopped after 6 months), skin hyperpigmentation I noticed a difference after about 3 months of taking it, but it took 6 months to be fully effective. I have been taking it for 3.5 years (with 1 year hiatus due to pregnancy). It worked great for a while, but now it is starting to fail. I'm a little disappointed that I can't use it any longer since it was so easy to pop a few pills with very minor side effects. F 32 3.5 years
400mg 1X day
9/8/2014
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 1  Erosive Osteoarthritis Rash that started from my chest and within 2-3 days had covered my entire body, told by my dermatologist that I was one step from Stephen Johnson Syndrome. I had a severe rash for 3 weeks and retained fluid, the pain was excruciating. My GP placed me on high dose of prednisone 50mg for 4 days reducing till I was at 12.5mg then to stop, when my rheumatologist prescribed this medication I was not told that a rash was a side effect, I called him to tell him I was getting a rash and he totally wasn't interested, just told me to see my GP, lucky that I did as I may not be here to talk about it. This medication takes approx 8 - 12 weeks to take effect so having a reaction 2 weeks into the course is quite normal, I also had excruciating bone pain about a week into commencing the medication. The dermatologist that I was referred to for the rash said that it is quite common for this to happen with this medication. GP's aren't too familiar with it. I am now having twice daily wet dressing wit More research needs to be done and better documentation on reactions needs to be noted. F 52 14 days
200mg 1X day
9/8/2014
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 2  RA Stomach cramping and frequent urination that leaves an annoying feeling after urinating with not being able to completely empty bladder. This happened during the day, but more so during the night. F
400mg 2X day
9/5/2014
 4  Skin lupus Stomach upset I haven't felt this good in years. Face is clearing, joint pain eased, wake up in the morning and feel normal. It's even helping with fatigue. A miracle & I have tried everything. My immune system was totally hurting me everyday. F 48 1 months
200 mg 2X day
8/13/2014
 5  mild lupus I don't think it agreed with me at first. I had brown urine, headache, no appetite...Dose got cut in half, then ok...I asked if I could try cutting it in half again to 200mg every other day...so far so good...as it takes a while to work, but builds up in your system... My energy is back!!!! but still have the aches at times... F 57 1 years
200mg 1X O
6/11/2014
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 5  Lupus Have been on this drug for many years with great results. Really helps with aches and joint pains and hardly any side effects F 45 7 years
200mg
4/26/2014
 2  RA Dizzy, upset stomach, back pain and side pain, abdominal cramps, leg cramps, rapid heart rate, anxiety and body felt covered in bruises Before taking Plaquenil my only symptoms were joint pain and fatigue. Now, after being off of the meds for a few weeks I still experience back pain, side pain, cramps, rapid heart rate and joint pain. My dr says the symptoms i am experiencing are not from the drug but I never felt any of these things until a few days after being on the meds.. F 19 3 months
1X day
4/17/2014
 1  diffuse joint pain, myositis quite severe depression, easy bruising, extreme fatigue, and more severe joint pain - was getting flare ups on it - some eye effects - I was getting so sick I thought I needed to take methotrexate - so I stopped the medicine and have never felt better in my life. No joint pain whatever, no flare ups no fatigue - this drug was like poison to me and I didn't realize it until I stopped it. F 55 4 years
200mg 1X day
3/21/2014
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 4  Sjogrens Farts are uncomfortable and embarrassing. I can't wait to get over this! I hope it works for my pain and swelling. F 54 2 weeks
200mg 2X day
3/12/2014
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 2  Rheumatoid Arthritis I was put on plaquenil and salfasalazine and I had terrible acid reflux and burning in throat and a lump in my chest, Rheumatologist said to stop the salfazine but stay on plaquenil but after an extra 2 weeks on it the symptoms are not getting any better so was thinking of stopping all the drugs F 56 1 weeks
400mg dail
3/9/2014
 5  discoid lupus, R A TERRIBLE TERRIBLE SMELLY WIND - TOTALLY EMBARRASSING , FARTING ALL DAY F 58 3 weeks
30mg 2X day
2/16/2014
 4  hep c arthralgia Mild g.i.cramping and nausea that decreased after a fee weeks. F 60 6 months
40g
2/15/2014
 4  RA diarrhea and bloating i want to be able to take it but this diarrhea is awful! F 63 2 years
200mg x's 2X day
11/24/2013
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 1  Rheumatoid Arthritis Severe red rash started on my chest, abdomen and back, then gradually worsened and spread to the rest of my body. The rash was relentlessly itchy and continued to worsen even after I'd stopped the Plaquenil and been on Prednisone for several days, though it eventually responded to the steroids. F 33 12 days
200 mg 2X day
10/14/2013
 5  APS and Fibromyalgia Nausea, diarrhea, stomached cramps, gas I am working my way around the side effects because I have not felt this good in five years. I hope it lowers my blood clotting proteins so I can lower my Coumadin or get off of it all together. I feel almost like a normal mom of the best 7 year old girl in the world. F 42 1 weeks
200 2X day
9/8/2013
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 1  lupus/udmctd Depression, Bloating, gas, rapid heart beat F 27 8 days
400ng
6/23/2013
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 1  Lupus Awful drug, started 3 weeks ago, since then I have constant diahrea, headaches are worse, little red dots on my face, and woke up yesterday to a dark circle under my eye, and lost 4 pounds. Called DR. said there was no way it could be related to Plaquenil since I had been on it for 3 weeks and to continue. Ughhh at a loss never had these symptoms before. Has anyone had similar expierence? F 45 21 days
200mg 2X day
6/22/2013
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 4  Probable sjorgrens /lupus? Ra? Confusing had GI issues before drug, but daily nausea and heart burn is new. Fatigue less with drug, depression less with drug, pain less with drug. It was fast onset of disease,... So hard to tell if it is going away from drug, or subsiding naturally. Is the GI stuff from drug, or continued progression of disease. Only on it 3 months, got eye exam before taking drug for baseline. I'm gonna stick it out on the med and see Better than where I was I just hate medication F 43 1 days
200mg
6/19/2013
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 2  fibromyalgia Intestine issues Migraines The first night I took 2 pills (one AM, one PM), I could feel my intestines jumping all night long. After a few days I cut down to just one pill in the morning. I still felt on the edge of an IBS attack and experienced headaches nearly every day I was on this med. It did not help me and the side effects were awful. My dose was average to low, but my body is sensitive to medication. Drug has the potential to cause permanent eye damage, but my doctor did not mention the required periodic eye exams F 38 2 months
1X day
6/14/2013
 2  Seronegative Rheumatoid Arthritis Mild diarrhea only for the first few days. Other than that no stomach ache if taken with food. It may have started helping on or around the fourth month because foot pain eased and it was a little easier to get out of bed, I did have some of the worst flairs ever on it. Started getting flu symptoms, fevers, swollen glands. Had extreme dizziness and extreme hair loss. I don't know if the hair loss was from the BCP that I started around the same time or the Plaquenil, but it is copius hair loss. Very depressing. I quit the med because I didn't see a lot of improvement and I wanted to get rid of the awful dizziness and hair loss. If the hair loss continues then it is probably the pill. Plaquenil works for a lot of people, I will restart it if the hair loss is due to the pill. F 4 months
200 mg 1X day
5/24/2013
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