PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Lupus On 200 mg 2x per day - severe muscle pain/weakness & joint aches. After lowering to 1 tab per day - within 1 week, severe reaction - large itchy purple patches. Started with itchy scalp & burning indegestion feeling, trouble swallowing. Turned within a few days into large purple hot itchy welts head to toe - hospitalization was necessary. Admitted from ER spent 5 days in hospital on heavy doses of steroids, antibiotics & atarax (benedryl didn't cut it) after a week, I'm home - rash more like prickly heat now - hands and feet (top and bottom) incredibly itchy feel very run down. I guess it works for some people, not me - if you have ANY reactions that are abnormal - talk with your doctor IMMEDIATELY I don't wish this on anyone F 44 21 days
5/23/2009
 5  Osteo and Psoriatic Arthritis SMALL AREA OF ITCHING ON MY MIDBACK AND STRANGE, BIZARRE DREAMS. I HAD ACHING IN FEET, HANDS, KNEES AND SHOULDERS. WITHIN TWO TO THREE WEEKS I WAS ALMOST PAIN FREE. HAD MY EYES CHECKED AND EVERYTHING IS FINE. I HAVE QUARTERLY CHECKUPS WITH MY RHEUMATOLOGIST AND HAVE BEEN DOING WELL. F 62 1 years
5/20/2009
 3  Inflammatory Arthiritis Diarrhea is really the only symptom I have experienced. I have bad joint swelling in my knees, spine and wrists. This medication has slowly been working. I dont feel 100% just yet, but I can tell something is starting to work. I have had only one flare since taking this medication. I hope as the months progress I will feel even better than now. F 28 1 months
5/20/2009
 2  Lupus/"Connective Tissue Disease" Diarrhea, nausea, dizziness and vertigo accompanied by tingly feeling in face, pain below my right ear, severe heartburn. I was managing migraines with other medication but once I started the Plaquenil, the headaches also started coming back. While the chronic fatigue and joint pain has lessened, I would rather have that than to constantly be dizzy and nauseous. I can barely function. The inability to function and the fact that I am constantly feeling sick and dizzy is beginning to cause a bit of depression. F 36 1 months
5/11/2009
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 5  Lupus No side effects. I've been taking Plaquenil for three and a half years. Since Plaquenil is a disease modifying drug, I would be afraid to be without it. It can do wonders for Lupus symptoms and keep antibody production down. I think it can make a big difference long term in the severity of Lupus. F 46
5/7/2009
 2  RA Break-outs on strange parts of my face. Didn't control my RA in conjunction with Remicade treatments. F 26 12 weeks
5/2/2009
 5  Incomplete SLE EXPLOSIVE diarrhea, reflux, gas The diarrhea seems to have passed, but had it continued it would have been a real problem - it would come on with no warning, no cramps... but a really good cleanout about 1 hour after taking the pills (even with food). Will try acidophilus. I had reflux before taking Plaquenil but it has worsened so I don't wear tie shoes anymore, just slip ons. As for the gas.... the dog did it! After 6 years of symptoms and almost losing my job, in 5 weeks I have NO joint pain, NO night sweats, NO fever, NO kidney pain. I am still very fatigued but that is starting to improve too. I am getting ready to go back to work full time. F 37 5 weeks
4/29/2009
 5  Lupus Some stomach upset (morning nausea, diarrhea, both of which I've had issues with before), weird dreams, feeling wired/jittery sometimes (which may just be me getting used to not being exhausted all time, for four straight years) Plaquenil has changed my life. I spent four years with swollen, stiff joints (all of them), migraines, horrible nerve pain, complete inability to concentrate, and constant exhaustion. All of that is completely gone. F 21 2 months
4/25/2009
 1  possible ra after 4 months i started to have needle like itching sensations only in one tiny spot. NOW it is on both arms, upper chest and small areas of my back. I told my rhuemy about the itching and he didnt say anything, so I decided to stop the meds (200mg bid). I wear cold wet towel on my arms and another small one to touch the other itchy areas. It helps but I can still feel the itching elsewhere. You can't live like this! I go to work and try not to show my scratching. This morning (2am) I woke up and took 2 benadryl, zyrtec, and slathered on benadryl and hydrocortisone creme. Still not enough to reduce the itching entirely. I will be looking up more info and then go see a dermatologist. Never again! F 51 4 months
4/23/2009
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 3  erosive inflam osteo both hands possible photosensitivity, feeling a little wired, no GI Hard to sort it all out in light of simutaneous taper of darvocet(bad drug for chronic pain)and use of NSAID only prn now. I also have found intjection into joints under fluor as outpt procedure very helpful to function-I have need to hand right for my profession and I've accepted a new project F 67 5 days
4/18/2009
 4  RA Have been taking Plquenil for 5 years together with methotrexate. Over the past 6 months I have expereience severe skin itching on my upper arms front and under. Enough to keep me awake all night scratching. I have broken skin with scratching. It lasted for about 2 months, stopped, and started again about 6 weeks later. Will discuss with rheumatologist. F 59 5 years
4/12/2009
 4  Mixed connective tissue disease I have felt great since I've been taking Plaquenil. My body responded positivly. However, for the first time ever I have ACNE! Has anyone else had this problem? I can't think of any other reason I this would have happened. I am so upset about it, it's making me depressed. My doctors said that Plaquenil would not cause ACNE. I'm in desperate need of advice. F 23 2 weeks
4/9/2009
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 4  severe erosive OA of both hands None that I am aware of. Have been on Medrol for over 1 year and now weaning off. Medrol caused insomnia. Hope when I get off the medrol I will get back to a normal sleep pattern. Have been to the eye Dr. for exam and have no problems. F 63 3 months
4/4/2009
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 1  RA Horrible diarrhea, no appetite (not a bad thing), and then after about a week and a half, I woke with hives or maybe it would be just a rash. The itching is UNBELIEVABLE! I knew right away to stop the plaquenil. Doc put me on a high dose of prednisone (YUCK) and antihistimine. Now, four days later...I have barely slept, the itchiness is going to make me loose my mind, I'm grumpy, depressed, anxious, and ready to cry at the drop of a hat. Top it all off, the plaquenil did nothing for my RA I dont think. Wish I had never taken the stuff. I even questioned my Rheumy when he prescribed it as I have psoriasis and it can make it worse. First time I have ever second guessed a doctor and I wish I had gone with my gut feeling and said no I dont want it. F 37 12 days
4/2/2009
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 5  RA/connective tissue disease/lupus diarrhea, gas, bloating, ringing in my right ear. Since taking plaquenil, decreased swelling in fingers and less pain in all my joints. Am able to work out 4 days a week. Not as fatigued during day as I was prior to taking this medication. Feeling a whole lot better! F 39 2 months
3/31/2009
 5  Inflammatory Arthritis Gas, upset stomach for first week or two This medication has helped me greatly, significantly reducing fatigue and joint pain. F 44 4 years
3/31/2009
 1  Rheumatoid Arthritis After 1 dose - severe muscle cramping and spasms for over 24 hours. It seems to have to triggered my fibromyalgia which was almost under control with medication (Cymbalta), and caused a worse flare of my RA - joint swelling and pain increased considerably. I was really hoping Plaquenil would work as it's one of the safer Rheumatoid Arthritis treatments. F 38 1 days
3/30/2009
 5  Connective Tissue Disease/Lupus None I had such bad pain I couldn't walk without my bones cracking. I take plaquenil everyday 200mg. It has truely improved my life. Still pain bothers me every now and then, but I wouldn't be able to go on without this medication. It has helped me ALOT. If I miss taking the pill for a few days, I notice a big difference. F 18
3/23/2009
 1  primary sjogren's most horrible medicine,from a happy mom I turned into a monster mom,couldn't sleep,the brain was awake all the time,agitated,furious,angry at the smallest thing,went totally crazy,pain in right ear,heavy headedness,weird scary dreams..NEVER listen to your doctor,my rhumotologist said it was harmless.......*%&$#@ still recovering! I thought I would try this but am sorry I even started it,I trusted my doctor and took it but regret to this day.She should have honestly told me that it could have other side effects ,all I was told was maybe stomach upset/rash etc. I honestly was close to having a nervous breakdown.....I thought I had gone crazy!My kids/husband was so scared!I was ANGRY!AGITATED! F 46 3 weeks
3/23/2009
 5  Sjogrens Blurred vision first two weeks, slight itching on entire body and forgetfulness. Plaquenil has helped me with Sjogrens a tremendous amount. When I went to see the Rheumatologist and he told me I had Sjogrens, I was in denial and didn't want to take the pills. I also have Raynauds, and don't take any meds for this. I was getting worse everyday. I started with one pill in the morning and then accepted what I had and started taking the second pill. Within 3 weeks I noticed a huge difference. I couldn't even swallow my food and would wake up at night with my eyes in pain. I was having severe insomnia for about 1 year and I now sleep through the entire night. My hair looks like it did when I was 20. My skin now has oil in it. Before my hair was dry and my skin was always dry. I'm very happy with plaquenil. I've already seen the eye doctor and plan on seeing her twice a year. I still have minor problems, like my eyes hurting or dry mouth, but compared to how I felt, this is now tolerable. F 47 9 months
3/22/2009
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