PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Sjogrens Diarrhea, blinding headaches, eye pain and dimmed vision, insomia,itching everywhere, ears ringing, emotional, muscle weakness, dizziness Yes it helped within a week of taking it for joint pain but the side effects were overwhelming F 40 3 weeks
400mg
6/15/2016
 4  LUPUS/ RA FIRST 7 DAYS, NO SIDE EFFECTS AT ALL, ON 8TH DAY I INCREASED TO 200 MG, TWICE A DAY AS DIRECTED......NO GOOD! :( SEVERE DIZZINESS, VERTIGO, NAUSEA, HOT FLASHES...FELT HORRIBLE! CALLED RHEUMATOLOGIST AND WENT BACK TO JUST 200MG A DAY. I STILL GET DIZZY AND NAUSEOUS BUT I AM REALING THAT IF I GET HOT, THAT'S WHEN IT HAPPENS. I AM POSITIVE WITH A LITTLE MORE TIME ON IT, AND A FEW ADJUSTMENTS, IT WILL BE GOOD. SINCE STARTING PLAQUENIL, MY ENERGY LEVEL HAS GONE WAY UP AND THAT DEBILITATING FATIGUE IS SO MUCH BETTER. I AM HAVING ALMOST NO JOINT PAIN AT ALL. THE CHEST PAIN I WAS HAVING REGULARLY, SOMETIMES LASTING AS LONG AS 24 HOURS AT A TIME, HASN'T OCCURED SINCE STARTING THIS MED. I AM DETERMINED TO GIVE THIS MED THE 3 MONTHS TRY MY RHEUMATOLOGIST SUGGESTED AND GO FROM THERE! I SEE MAJOR IMPROVEMNTS AND NOW WITH THE REDUCTION IN THE AMOUNT OF PLAQUENIL TAKEN DAILY, THE SIDE AFFECTS ARE GETTING BETTER ALSO. F 45 18 days
2000MG. 1X day
6/2/2016
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 3  Lupus & Sjogerns About 7 days in I had a few red spots on my L thigh. Within 3 more days I had a rash covering both thighs,butt-low back, abdomen,chest,neck. I spoke with my pharm he instructed me to dc the plaquenil start benadryl and contact my rheum ASAP . Saw Rheum next day agreed with pharm on dc of plaq, added prednisone, said severe rash and definitely allergic to plaq. I was seeing some improvements while on med. Less pain in hip was definitely only positive lol. Also had lots of nausea felt like a fibro flare very flu-y. I thought at the time it was just my body adjusting to the new med. But,I think it's more likely part of the allergic reaction F 47 10 days
200 mg
5/25/2016
 1  systemic lupus Omgosh....hyper,extreme anxiety,excessive talking and hard to get to sleep Rhem said it would help with pain and lupus hurting my organs. F 47 2 weeks
200mg
5/4/2016
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 3  SLE and RA This is for the GENERIC: extreme nausea and vomitting to the point where taking Zofran to stop it did not help (and it normally ALWAYS works!). Insurance denied approval for brand name. I was able to identify 5 ingredients in the generic that is not in the name brand that could be causing the problem. Also, any cut or wound I got became difficult to heal, though rheumy said Plaq doesn't cause issues with this (my PCM disagrees). Besides the nausea/vomitting, it was helping alleviate my symptoms far more than I realized. Though I still had fatigue, it improved somewhat, the pain in my joints had decreased significantly, and I had these weird "nodules" that used to pop up under the skin of my arms and legs that disappeared. Getting eye exams every 6 months to check for Plaq toxicity...so far so good. F 42 9 months
200 MG 2X day
4/13/2016
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 1  Linear Scleroderma Horrible rash covering face and body that does not respond to Prednisone or antihistamines as well as bloating and pain in ribs. This drug is like poison. I was at the doctor, ER and dermatologist and the rash is getting worse. I can't go out in public. I've been off Plaquenil for 6 days and the rash is getting worse. I was told by the ER that the half life of the drug is 50 days, which means it takes 50 days for 1/2 of the drug to leave your system. Please do your research on this drug before taking it and make sure the benefits are worth the risks. F 51 20 days
300 MG 1X day
4/12/2016
 2  Lupus At first it helped with my pain,but that didnt last long maby 3 months at the most.And now for the past 10 months every time i take it the inside of my ears get very hot and itchy, and i itch all over so i dont get much sleep,plus my pain is worse then ever,my whole body get numb and tingle like every thing is going to sleep even my face and my head hurts, and feeling sick to my stomach. I spend most of the time in my bed exhausted or sick,in 10 months my cushion between my joints in my knees and my neck have worn to the bone. I thought its supose to protect my bones and organs,and i also have cronic stage 2 kidney disease. How so fast Its just not working for me F 50 10 months
400mg
3/19/2016
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 1  ra Agitation,stomach cramps,brainfog,itchiness,fatigued,overall joint pain worst than I had previously felt. Not myself,in there but no input? I was using generic brand until 3 days ago. Food tastes lousy lost weight.I quit cold turkey is that wise now I feel good.I can think& discern.Please answer the question and what is yhe connection between hydroxychloroquine and summer and winter. Oh!I forgot the sweats. side effects need to be made aware of not trial and error of individuals! F 69 2 months
200mg dail
3/12/2016
 1  Possible lupus and RA Day 4 experienced intense scalp itching that progressed over the next 4 days with development of a rash / hives to my neck, face, chest and back. Got a steroid shot at a convenience care clinic on day 10 (I had already stopped the med on day 8 which was yesterday) and given a prescription for a 6 day dose pack that I started today. I've already been taking 2 Claritin in the AM and 50 mg of Benadryl at night for 2 days with little help. It's the weekend and the rheumatologist won't be back until Monday. I am lying in a tub of warm water at 2 am because I am miserable. I'll take the joint pain and fatigue over this. I've neve had an allergic reaction to a drug before until now. I won't try it again. F 51 1 weeks
100 1X day
3/6/2016
Email
 4  Rheumatoid Arthritis I am having terrible constipation, mood swings, anxiety, bloating. Can't seen to find constipation as a side effect but it's just to coincidental. But overall the Plaquenil has helped. F 60 2 years
2/2/2016
 1  Fibromyalgia, Artritis. I started taking 200 mg Plaquinel twice a day. On Jan 11th. I noticed after a week extreme itching. Since I get winter skin I just assumed it was that. But then the itching became severe all over my body. Then patches of hives started appearing. The my Vagina became red,swollen and itchy. I can't quit itching. I was taken off this medication due to severe allerguc reaction. My mother takes it and says it helps her greatly. But it has caused severe vision problems she has two cateracts. F 45 10 days
200
1/25/2016
 3  pain Anxiety, weakness It's early yet. This drug in combination with etodolac is reducing my pain, which is fantastic. But it makes me anxious, a big problem. Obviously I've got a long way to go to learn its long-term efficacy - and whether I can stand this side effect. F 52 2 weeks
30 2X day
1/2/2016
Email
 3  RA Leg pain weightliss no appetite loss of hair memory loss weight loss depression anxiety on anti depresent and anxiety meds Also worried what is doing to my eyes everytime go to eye doctor send me to retna Dr one doc says have start of maculardegeneration my granda mother had that reading words run together F 58 2 years
300mg
12/8/2015
Email
 1  For rheumatoid Arthritus Red blood spots big brown spots arms bleed easy forgetfulness hair loss weightloss leg cramps fatigue headaches and more Can I quit meds F 59 1 days
300mg
11/30/2015
 4  Lupus, shogrens, After two months; I have a huge hive just on my left side of my waist it's,itchy, and hurts and hot!help please? F 62 2 months
400mg per
11/23/2015
 1  Rheumatoid Arthritis Itching and hives Absolutely NASTY drug. Thanks to this, I look like "The Thing" from Fantastic Four. Twice in one month of taking this poison, I have awoken to itchiness and hives that spread all over my body. The rheumy suggested that I take antihistamine everyday along with the Plaquenil to control the reaction, but it happened again and it's far worse than before. I'm really hoping that it clears up with the use of another antihistamine. This is a very nasty drug! I'm never touching it again. F 33 1 months
200 mg 2X
11/8/2015
Email
 5  Sjogrens I've found that this is a miracle drug for me. I had experienced fatigue,low blood pressure, dry mouth, dry eyes, my sweat glands were hardly working, dry skin, achy joints . I just felt awful and it had gone on for years! Finally diagnosed put on Plaquenil and after 5 months most of my symptoms are either gone or have subsided to a manageable level. F 56 5 months
400 MG 1X day
11/2/2015
Email
 5  Discoid lupus, sojrens Love this relatively inexpensive drug. Because of my prescription coverage I take generic, so I cannot compare it to the name brand. It has been a literal "put me back into life without severe pain" medicine. It has almost completely removed the pain in my feet and joints and kept my flare ups at bay. The doctor added 5 mg of prednisone a day 5 months ago for swelling of my joints. The 2 medications are working HOWEVER I have had easily bruising and any little cut scrape bleeds like I have been gashed. Will have the doctor reevaluate my dosage of plaquinel in October to possibly ease the side effects. F 55 2 years
400 mg a d
9/27/2015
 1  SLE, RA Paranoid, extreme body flushing, gas, pain in back of throat, twitching Horrible, I was on the generic so do not know if name brand would be better. F 54 2 weeks
200
9/20/2015
Email
 5  autoimmune disease like lupus no side effects now and in the beginning, I believe I remember some visual disturbances like looking at a old tv with no cable my autoimmune disease is unspecified. I have elevated RA factor. My ankles, wrists, knuckles will get really intense arthritic pains if I miss the plaquenil. I have never taken the generic and hope I never have to. Another bonus to the plaquenil is that it thins my blood, I guess? I have factor v leiden, a blood clotting disorder and this lupus like autoimmune disease must also exacerbate the clotting issue because before plaquenil I had 7 ministrokes (TIA) btn 2010-2014 and since beginning plaquenil, I have not had any! I feel protected for the first time in years and I have been on a blood thinner since 2012. F 36 1 years
200 2X day
8/18/2015
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