PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  sero-neg RA Severe depression (and i mean severe!), gas like you wouldn't believe, nausea, cramps, total loss of interest in everything, no energy, panic attacks, dizziness, sun sensitivity It did solve my rash from RA, and pain lessened in about 3 weeks which was great. Just couldn't live with wanting to kill myself because of the depression. F 33 1 months
5/29/2005
 4  overlap connective tissue diseases night sweats, some hair loss, that has leveled off, very dry skin, blurred vision, get many headaches, but have had a hx of headaches and migraines. First time I took it for six months (200 mg BID), and in addition to afformentioned side affects, iI was getting very large dark bruises that would not go away for months. Second time around, and I'm not bruising. Skin very itchy and looks much older since began taking. Has made pain much more tollerable. Can walk in the morning now. Have a good deal of fatigue, but have multi- connective tissue diseases and poly-arthritis. Take 6 other prescriptions as well, so cant say if Plaquenal is affecting mood and fatigue. F 46 1 years
5/24/2005
 5  SLE no real side effects I take 200 mg twice a day and this has been a miracle for me. I love it, however recently my doctor changed it to 200 mg once a day and I have started to get headaches and night sweats again. Has anyone else had this experience? F 19 1 years
5/21/2005
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 4  Sjogren's with Lupus First couple of weeks, nothing - then extreme nausea and occasional vomiting for about 4 weeks. Following 6 weeks after that, mild nausea and some hair loss. After that, though, nothing eventful, although when we change my dosage I do tend to develop painful (and HUGE and extremely unattractive)acne cysts on my chin. Before the Plaquenil, I would sit on the floor of the shower, crying, because I just didn't know how I was going to make it through another day at work. The exhaustion was completely oppressive. I have to admit, during the extreme nausea phase, I was ready to beg the doc to take me off the drug I was so miserable. But the difference it made in my life was remarkable. I have been able to go back to full-time acting, which I thought was not going to be an option for me again. My doctor has been trying to taper me off for the past year (my husband and I are thinking about kids). However, since the taper, I have noticed that I am having episodes more frequently, feeling nauseous more consistently, the exhaustion is beginning to return, and my chin looks like a minefield. So, we'll have to see what happens from here. F 34 5 years
5/13/2005
 3  sle severe hair loss, as a women thats heart breaking. depression, bad cramps, hearing problems. since going up to 800mg its finally starting to help a little but really going bald now. loss interest in food and only drinking water as i feel thirsty all the time. eyes seem ok but do lose focus at times. still feel tired though wonder if ill ever get my life back F 31 3 months
5/4/2005
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 3  sle severe hair loss, as a women thats heart breaking. depression, bad cramps, hearing problems. since going up to 800mg its finally starting to help a little but really going bald now. loss interest in food and only drinking water as i feel thirsty all the time. eyes seem ok but do lose focus at times. still feel tired though wonder if ill ever get my life back F 31 3 months
5/4/2005
 3  Severe Chronic Urticaria Diarrhea, loss of appetite, fatigue Today is the 5th day taking Plaquenil 100mg daily. It is also the first day ive had pain free! Although very tired, no pain is definitely worth it! It has also been 5 days since i have had a flare up of other symptoms. Next week i start on 200mg a day. I almost cannot wait. I am hoping this also means i can slowly decrease the amt of steroids i am taking! My fingers are all crossed!! F 30 5 days
4/24/2005
 3  Severe Chronic Urticaria Diarrhea, loss of appetite, fatigue Today is the 5th day taking Plaquenil 100mg daily. It is also the first day ive had pain free! Although very tired, no pain is definitely worth it! It has also been 5 days since i have had a flare up of other symptoms. Next week i start on 200mg a day. I almost cannot wait. I am hoping this also means i can slowly decrease the amt of steroids i am taking! My fingers are all crossed!! F 30 5 days
4/24/2005
 5  Lupus I haven't experienced any side effects. This is my second time taking plaquenil/hydroxychloroquine. 200mg 2 times a day. I was first diagnose of lupus in 1995. I went in remission in 2001. I decided to stop taking plaquenil. I had no symptons in the last 4 years. About 2 months ago I start having swelling and pain in my feet. So I started back taking plaquenil. I'm now back feeling great! F 33
4/22/2005
 5  arthritis None thank god for this drug. I have been on it for 9 years and with out it I would not be able to walk. F 40 9 years
4/21/2005
 2  Fibromyalgia/Lupus I have been feeling incredibly edgy and restless and easily irritated since being on this drug. Constant headaches, diarrhea 5-10X a day, GAS and severe abdominal cramps with a raging thirst that nothing seems to satisfy. Also very tired and no energy with shortness of breath and heart seeming to jump out of my chest at the least exertion. Anyone else feel like this after being on this drug? How long do these symptoms take to disappear? I did great while on 10 mg of prednisone w/o any of these horrible side effects! F 44 14 days
4/19/2005
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 3  Mixed Connective Tissue Disease HORRIBLE acne cysts on my face and sometimes chest. Trouble staying asleep at night. Weight gain and bloating. It's working well for my joint and muscle pain, but it doesn't do much good when I'm embarassed to leave my apartment b/c of the acne! F 27 2 months
4/18/2005
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 4  Rhumetoid Arthritis Some stomache pain, only if I take on an empty stomache. This has made a huge difference in my life. I finally able to function normally. F 23 2 months
4/7/2005
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 5  RA - Sjogrens Itching, some dark spots on my face, but this could be hormonal. Biggest concern is blurry vision and light sensitivity. Seem to be developing retinal tears, first in one eye and now the other. Eye exams every six month, we'll see. All in all, this drug has positively changed my life. I also take bextra and feel lucky that I don't have many side effects at all. F 43 2 years
3/26/2005
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 2  Systemic/Discoid Lupus Extreme gas, bloating, weight gain, sleeplessness. First and second times I took Plaquenil, I had no problems. The third time around, I had many problems. The gas was unbearable. F 34 30 days
3/7/2005
 4  Systemic Lupus and Sjogren's Many brown FRECKLES all through my mouth and lips (hate this side effect), darker fingers and thinning hair (hair loss could be due to the lupus or just aging), and GAS. I get my eyes tested every six months. No eye problems detected. I had a life threatening flare of lupus and TTP (platelet and red cell disorder) four years ago. Went on Plaquenil for two years along with Prednisone. Went off both w/doc's okay when I appeared to be in remission. After one year off Plaquenil, I developed Sjogren's Syndrome, Raynaud's and more fatique and joint pain. I'm back on it at 200 mg/day. I credit Plaquenil with reducing my symptoms and allowing me to get through the summer without extreme light sensitivity, rashes and weakness. I don't have to take Prednisone now. F 45 3 years
2/23/2005
 4  RA type of sx-periarthritis MAJOR GAS- helped to take acedophyllis pills from vitamin store. Weird dreams Itching I feel better than ever most of the time. Still have periods of pain and fatigue but not lile before F 44 1.5 months
2/22/2005
 4  RA type of sx-periarthritis MAJOR GAS- helped to take acedophyllis pills from vitamin store. Weird dreams Itching I feel better than ever most of the time. Still have periods of pain and fatigue but not lile before FIRST ONE HAD WRONG EMAIL F 44 1.5 months
2/22/2005
 3  psoriatic Arthritis Gas,Diarreah,RIngning of ears,Sleeplessness found it to be somewhat helpful, found the sleeplessness bothered me the most. F 31 2 months
2/15/2005
 3  Sarcoidosis Itchy eyes, gas and then some more gas, halos in vision at times. White cell count was low before taking plaquenil. But now a reading of 2.6 and further blood tests pending next visit. Have had eyes checked and center of the eyes look good. Can't see colors well before or after the plaquenil. What appears to be new areas of granulomas popping up and the old ones diminishing in size. Skin pigmentation coming back. M 43 4 months
2/14/2005

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