PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  non spec. con.tis.disorder, fibro ringing in ears, abdominal pain and cramps, extreme fatigue only been on it for 2 weeks, but don't think I can put up with the side effects F 58 2 weeks
4/7/2008
 1  rheumatoid arthritis steven-johnson syndrome will never take it again, it is dangerous F 49 21 days
4/7/2008
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 5  Lupus In the beginning, stomach upset and could not sleep. I take it every morning and these side effects went away within a couple of weeks. It is a nasty tasting pill so take with juice or something to mask the taste. I began taking Plaquenil in January 2007. I was terrified of the possible side effects with vision so I have yearly eye exams. I used to get constant fevers, mouth sores and pleurisy. Since beginning the Plaquenil, all of this has stopped. I only need 200mg a day because of my weight (130 pounds). I was told the higher the dose, the greater the risk of eye problems. I am very thankful for this drug. F 38 16 months
4/2/2008
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 4  RA small amount of nausea; some diarrhea; curbed appetite; gassy & gurgly GI (almost like Winnie the Pooh--a rumbly in my tumbly)sorry, the only way I could describe it I do feel better, but the last couple of nights have been sleepless (can't get to sleep, even with Ambien CR until very late)I was originally diagnosed with Fibromyalgia and now a confirmed diagnosis of RA. I am hoping I can go off some, or most, of the the other 11 meds I take at bedtime. I am a pharmacist and need to be able to stand all day and not take meds that make me foggy. I haven't been on very long but have noticed some improvement. I am still a good barometer as to when the weather will change,(achy, exhausted, depressed) hopefully after some time on the Plaquenil that will change. My rheumatologist seems to think I will respond well. I want my life back!!!! I have 2 small children and a husband who want me back!!!! F 43 21 days
3/26/2008
 4  Sjogren's Syndrome Nausea (briefly); bloating and gas I have recently been taken off Plaquenil due to extreme pain in the muscles in my legs. I am very worried that the joint pain, rashes and fatigue will once again overtake my life. Has anyone found anything over the counter that has helped with joint pain? F 44 9 years
3/24/2008
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 2  rheumatoid symptoms in joints BITTER/SOUR TASTE IN MOUTH ALL DAY AND NIGHT. CAN NOT RELIEVE IT IN ANY WAY. SOMETIMES MY TONGUE IS NUMB FEELING. ALMOST AS SOON AS I BEGAN TO GET JOINT PAIN RELIEF I STARTED WITH THE BAD TASTE IN THE MOUTH. IT DRIVES ME CRAZY. WHAT A CHOICE! F 51 3 months
3/19/2008
 4  ra gas, stomach pains, weight loss I have been on plaquenil about 6 months. I have felt a lot better . I can actually move again, so far it has been life saver F 59 6 months
3/15/2008
 3  Lupus Gas and Tired I have only taken this for 2 weeks now but the gas in horrible and I have never been so fatigued in my life. I am afraid I will fall asleep driving home from work. Anyone know if this in normal in the early stages of taking this? I thought it was to help with fatigue. F 45 14 days
3/14/2008
 5  Sjogren's Syndrome, Fibromyalgia After 8 years, I developed severe thigh pain and muscle weakness. I found I had a very difficult time walking up a stairway on more than one occasion. It was great for improving the fatigue and joint pain of Sjogren's Syndrome, and helped lower my inflammation markers for a long time. I finally had to switch to low doses of Methotrexate three times a week to bring my rising Lupus markers under control. The thigh pain went away. F 58 8 years
3/1/2008
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 3  lupus A little dizzy & gassy(finally can get back @ my boys!)but new symptom is a fullness feeling in neck/throat & the need to clear my throat. Any one else experience this? F 47 8 days
2/29/2008
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 4  RA Gas,burping, bloating, acid reflux, stomach pain Had loose stools in the first 24 hours (I'm not prone to that at all so I'm sure it was the drug) but that cleared up right away. Actually, I'd have to say that it has improved my bowel function. It wasn't until the 30 day mark that this other GI stuff started. I did take several doses without food, so I'm wondering if that could have caused it. AT 10 days I started seeing big improvements in the morning stiffness that had been dogging me for months, so in that respect I was pleasantly surprised because I wasn't expecting any help before 2-3months. Dr. had said that patients continue to improve even more in the 6-12 month range and he didn't know why it takes so long. I had resisted these other drugs because of the side effects, but while the dr. was patient, he kept suggesting it. It has definately made an improvement in my condition. He says he's had a lot of success in patients like me, who have been on the drug for "decades" and that he's had no eye issues in patients F 52 34 days
2/26/2008
 5  Still's Disease Minor bloating and gas. It has workded wonders for me! Before being diagnosed by a Rheumatologist and being put on the drug, I was in and out of the hospital. Since I started Plaquenil the diesease has been held at bay. Thank God M 39 3 years
2/22/2008
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 5  MCTD Itchy Skin. A little more forgetful. This medication changed my life. It took a few months to start working, but when it did, everything just got better. My joint pain and rashes slowly went away, and haven't come back. I sometimes get rashes and joint pain every now and then, but very mild cases of them. I am so thankful for this drug. M 24 2 years
2/22/2008
 4  Lyme disease Major Gas, vivid dreams, extreme forgetfulness, itchy skin,lots of new freckles on back and arms, extremely bad taste in mouth all day and night. I don't know if this drug has worked or not yet. The side effecta are manageable. I hope it works!!!!!! F 36 1 days
2/5/2008
 1  RA Blurry vision, floaters dryness Didn't help mouth sores still had fatigue, joint pain F 38 6 days
2/1/2008
 3  Rheumatoid Arthritis Upset stomach, headaches, running nose, swelling of joints, extremely sensitive eyes. I haven't been using Plaquenil for long, so I guess it hasn't had enough time to start working properly, but I'm not sure whether I want to keep taking it or not, due to all the side effects, I'm not sure if it's really worth it? F 16
1/28/2008
 4  SLE bloated, nausea, gas, pigmentation changing (dark spots on face,neck, bend of arms/legs, inner thighs) Medication started working after 3 months, my energy level increased and joint paint went away. One of the side effects of plaquenil is skin pigmatation which I developed. So, due to the dark spots especially on my face, my dosage was lowered from 400mg a day to 200mg for about a month, but the pain and the fatigue came back. Doc has increased the plaquenil to 400mg every other day to see if the fatigue will go away. Not sure what we are going to do about the skin pigmentation, but if it increases my energy level, i'll deal with it. F 40 6 months
1/21/2008
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 3  MCTD When I first started taking Plaquenil, I experienced no results. It took about 2 months to start working. I also gained increased bloating, gas, nausea, hair loss and intestinal problems. Now life is better. Life is better as far as movement. Mornings are still rough, but once I get going I have a lot of energy. As a Kindergarten Teacher I need it, but by the fourth day I'm dragging and can only go to bed when I get home. Sometimes I can't turn this energy off and find sleeping at night difficult due to restlessness and large muscle pain. I still have the intestinal problems. I am trying to work the stomach issues out with dietary changes. I have severe pain in large and small muscles during my cycle. Sometimes to the point of not being able to get out of bed. I do however have more sunny days than bad. F 40 9 months
1/19/2008
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 4  SLE, Fibromyalgia Haven't noticed any until recently. Take 200mg x twice daily along with 5 mg prednisolone, 2 x 200mg Celebrex, 200 mg of Endep. Had severe pain, low grade fevers, exhaustion and awoke one day, 4 months after being diagnosed, and felt I had no life force in my body. I have found many items on natural therapies that have complimented the drugs. I have blurry vision in my right eye the last week or so. I tried to stop the plaquenil at one stage and broke out in rashes all over my body. Re-commenced and that now seems to be under control. Intend to try to reduce the plaquenil to 200mg daily but am looking for a natural product to assist. Back at work and am at about 85% and need to carefully watch what I eat and get the right amount of rest. I was in intense pain for months before I was diagnosed with Fibromyalgia Syndrome. Endep and Celebrex were prescribed and they have definitely helped as has a product called 5-htp which I purchase from an Internet company iherb.com. I also takeCo Q10 and Immune Renew from iherb for the lack of energy. F 49 2 years
1/5/2008
 5  lupus Took about 3 months for it to start working; about the first month or so I had stomach upset. Thank god for it--it has steadied my lupus and I am not having to be on methotrexate or prednisone or anything else. F 48 4 years
12/28/2007

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