PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Inflammatory arthritis Bloating, abdominal discomfort, nervousness, anxiety Finally received benefits from the drug after 10 months but I also need Celebrex. The nervousness and anxiety attacks force me to use anti-depressants and anti-anxiety medicines. Does anyone else have this problem? Those problems began about 3 months after I started Planquenil. I still have joint pain, but it has subsided significantly. F 36 15 months
4/24/2007
 3  SLE......joints and skin symptoms itching, face rashes, hair loss, gas and abdominal discomfort Rheumatologist wants me to continue it long term. I am not sure if these side effects are directly related to the Plaquenil or the dosage I take. I am on 200mg twice a day. I am experiencing less joint pain with the plaquenil and celebrex combination. F 62 5 years
4/11/2007
 2  lupus and sjogren's Memory loss, lack of concentration, blurry vision, my skin changed colors, and diarrhea. The doctor kept on saying that it was not the plaquenil. They wanted to give me namenda (for alzheimer). They said that I had cognitive damage. They sent me to therapy. I knew it was the plaqenil. As soon as I stop taking it, I was able to follow instructions on my job. I do not feel lost. My vision is better. My stomach is practically normal, even with Sjogren's syndrome. According to my doctor today I would be disabled taking more than 10 pills a day. I stop the medication with NEW doctor's approval, and I am doing great. People should find out if they really do worst without it. Temporary it can be taken, but all the time in a lot of case I do not think that is necessary. F 49 3 years
3/30/2007
 4  Sjogrens Syndrome none Helps greatly with Sjogrens related fatigue. No effect on dryness. F 45 18 days
3/25/2007
 2  sero-neg ra, /PsA (?) + others Decrease in appetite. Can only eat so much. No nausea tho' or other side effects. On 200 mg twice a day. After thinking it didn't work very well, was taken off, only to have increase in joint pain. Put back on after a week. It still doesn't address large am't of swelling or inflammation in feet, hands, knee; or the stiffness. A month later - prednisone 80 mg IM, the majority of swelling was gone, along with a good deal of stiffness. Pain still present, tho' much better. Now also on methotrexate, but will be tapering off plaq.as MTX increased. F 57 4 months
3/24/2007
 5  Palindromic Rheumatism Noisy bowels and slightly loose stool for about a month. Nothing since. It is a godsend for me. I still ache occasionally, but my bad pains have gone. I am now able to function again like a human being. F 28 6 months
3/15/2007
 4  SLE only experienced the nausea once in 4 months. uncomfortable bloating. weight gain (10 lbs in 4 months) extreme fatigue. mood "rollercoaster". i take 300mg/1 daily of plaquenil and 10mg/1 daily of prednisone. they have helped leaps & bounds for my joint pain and have kept my skin under control. i continue to have severe weight issues which have led to much sadness & feeling like a failure. (round face, jeans dont fit, tops too tight, etc.) i hope by april to only be taking 5mg of prednisone, if at all. *If anyone has any advice on weight management, I would really appreciate it. F 23 4 months
3/15/2007
 3  RA Plaquenil worked for me since 1989. My eyes were regularly monitored and up until this past August, they were fine. I now have to be taken off the Plaquenil, as I have toxicity in my retinas. I was told in the beginning to just keep having my eyes monitored and I would be fine. My eyes are NOT fine. F 42 18 years
3/13/2007
 3  RA Plaquenil worked for me since 1989. My eyes were regularly monitored and up until this past August, they were fine. I now have to be taken off the Plaquenil, as I have toxicity in my retinas. I was told in the beginning to just keep having my eyes monitored and I would be fine. My eyes are NOT fine. F 42 18 years
3/13/2007
 2  SLE, Fibroomyalgia, Arthritis, Sjog no side effects that I'm aware of. I've been on it @ 6 weeks and have noticed NO difference. I was told such wonderful stories about it, but haven't experienced anything. Taking 200mg BID. See my rheumie in a few days and will ask about it. F 55 6 weeks
3/11/2007
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 5  Yes Crazy vivid dreams too. I also feel a little light-headed. F 38 2 days
3/4/2007
 5  RA Crazy vivid dreams! No others. F 26 45 days
2/14/2007
 3  Sjogren's Syndrome From the 1st hour onwards: total shut down of bowel system, resulting in severe obstipation, water retention, weight gain. Also severe hypotension (extreme cold!). Loss of libido. Painful dry eyes and blurry eyesight after a few days. The good thing about Plaquenil is, it restored the mucous inner lining of my mouth almost straight off. Salagen worked heaps better and for the first time in years the saliva flow improved. But the other side effects had such a great impact that I halved the dose (from 400 mgs to 200 mgs per day). To no avail, unfortunately. I ended up calling my reumatologist. She thought I was having a severe allergic reaction and told me to quit Plaq immediately. So I've only used it for 10 days. Shame, it was excellent for healing my mouth. F 39 10 days
2/12/2007
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 1  active rheumatoid arthritis Sore throat, led to not eating much because of swallowing, nausea, food didnt want to stay down. Day of hospitilisation, diahorrea, vomiting, weakness , dehydration. This is written on behalf of my mother. Have had the arthritis for many years, told it active in October 2006. Saw speciialist Nov 2006. Had notice lumps in fingers starting to disappear in December 2006 but could of been result of other new medication at the same time. Admitted to emergency January 2007, because of weakness and diahorrea. Very dehydrated. Tests completed - small stomach ulcers, and severe Thrush up through chest and throat. Symptons only occurred in a matter of days, sore throat was checked by doctor prior, thought to be inflamed. Severe symptons only come on within two days and led to my death within a week. Was told amount of dosage was too high for this age, 200 mg.( 2 tablets) Dosage recommended for 25 yr old. F 76 8 weeks
2/5/2007
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 1  active rheumatoid arthritis Sore throat, led to not eating much because of swallowing, nausea, food didnt want to stay down. Day of hospitilisation, diahorrea, vomiting, weakness , dehydration. This is written on behalf of my mother. Have had the arthritis for many years, told it active in October 2006. Saw speciialist Nov 2006. Had notice lumps in fingers starting to disappear in December 2006 but could of been result of other new medication at the same time. Admitted to emergency January 2007, because of weakness and diahorrea. Very dehydrated. Tests completed - small stomach ulcers, and severe Thrush up through chest and throat. Symptons only occurred in a matter of days, sore throat was checked by doctor prior, thought to be inflamed. Severe symptons only come on within two days and led to my death within a week. Was told amount of dosage was too high for this age, 200 mg.( 2 tablets) Dosage recommended for 25 yr old. F 76 8 weeks
2/5/2007
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 3  Lupus, MCTD Very bad painful large acne cysts on my face. started on my chin and has slowly progressed all over my face. I started doing yoga and taking plaquenil shortly after being diagnosed and continued to do both for the past 2yrs. I have not had any joint pain since then but was told by my doc that my disease has been very active despite my lack of symptoms. Now I have very bad acne and am considering coming off of plaquenil. I would love to hear of any similar situations and of any possible solutions. F 39 2 years
1/21/2007
 4  Blood tests confirmed SLE/shogrens abdominal gas and gurgling. So far, that's all. (hope it stays that way!) Joint pain is all but gone. Knees still have some aches and joint popping, but nowhere near what they were. That all over feeling tired and achy is gone! Even tho my Dr. did not see any outward signs of Lupus (tell tale rash, etc) he decided to try me on this and it really has helped. I don't think I even realized how badly I was feeling until I stopped feeling that way. I guess I just thought it was normal. I'm really glad to find out that it is NOT! F 51 7 weeks
1/15/2007
 4  SLE / SCLE Gas indigestion, memory loss-short term, mood swings, Some hair loss. Sometimes I get this feeling that something is caught in my throat but it was in the 1st 4 weeks and has become less frequent I have been taking Plaquenil 200 mg a day for 3 months.Diagnosed March 06. Did not want to take this med. Told my Rheumotolgist no for months. Prior to taking this med I suffered from fevers, extreme fatigue, rashes, headaches ,and body aches and stiffness almost everyday. There has been a big improvement . I still have some bad days but they are becoming far and few between. Hope my eyes hold out. I do not want to go back to feeling the way I felt 4 months ago.I was barely able to get out of bed. I would recommend to at least give it a try it may work for you. F 49 90 days
1/4/2007
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 5  SLE Gastro upset, diarrhea. ?Acne A god send. After 3 years of being crippled by joint pain. Even after 6 weeks I am back at the gym every day and working again full time. Occasionally troubled by GI upset but I believe it may be caused by taking the drug on an empty stomach. Unfortunatley has not improved peripheral neuropathy but low dose steroid may work. F 33 6 weeks
1/1/2007
 3  connective tissue disease The Plaquenil causes intestinal upset regardless of how or when I take it. Plaquenil does provide some relief for my aches and pains, so I will not discontinue taking it. I am also experiencing trouble getting to sleep at night - a new experience for me. Could this be caused by the Plaquenil? My energy/stamnia has not improved. In addition to the Plaquenil, I take Celebrex for pain. F 58 4 months
12/24/2006

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