PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Rheumatoid Arthritis Irritability, anorexic (lost 10 pounds) food tasted metallic, no relief from joint pain, in fact I felt worse, muscle twitching @ night. This is an anti-malaria/lupus med as well. This stuff was like poison to me. Stay away from it. Hyaluronic Acid 50 mg. orally, + Glucosamine & Omega 3 plus prayers has helped immensely. :-) F 60 30 days
200 mg. 2X day
10/4/2011
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 4  Possible Sjogrens Sometimes a little dizzy if I don't take it with food. I want to eat less-Yah! I look forward to taking it each day. It lessens my pain and helps me bounce back from stuff much faster than usual. Much better than the other alternatives I think. F 56 5 months
200mg 2X day
9/26/2011
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 4  Undifferentiated interconnective di None that I remember when first taking but for approx. 8 years now I emit a BAD odour from FLATULENCE. Not the explosive kind, but seems like a slow leakage constantly, It is isolating and causes me to cancel many social functions. It was only in reading this site that I could see it may be the Plaquenil. Luckily it only became a problem towards the end of my working life. I am thankful for the way it reduced my pain & stiffness and gave me back my mobility and energy (if I also balance my life properly). Just want to know HOW to get rid of the flatulence side effect - and does Plaquenil cause a yeast overwgrowth? F 68 18 years
400mg 1X day
9/24/2011
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 5  Inflammatory rheumatism none that I notice I was in agony before taking it. Took about a month to kick in and it has saved my life and career. I have my eyes checked six-monthly but have had no problems. M 64 17 years
40mg 1X day
9/14/2011
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 1  lupus TERRIBLE POISON! I took plaquenil for a week and felt terrible. I noticed strange taste in mouth, terrible nightmares, and general awful feeling, fatigue, stomach problems. I discontinued. 2 weeks later I broke out in awful hives on face/chest. Dr. didn't believe me that it could be allergic reaction so he put me back on plaquenil for one more week, this time at 400mg/day. He thought it was lupus flare so I received very high pulse therapy treatment of medrol. I was in hospital for a week, I went home, and it got worse. I had to take 75 mg/day of prednisone. The second week of taking this poison I began hearing voices and noticed I felt much much worse and this time was convinced, despite all the doctors advice, that it was a severe allergic reaction. I had a skin biopsy done which confirmed it was an allergic reaction and not autoimmune related. I have experienced terrible effects. For almost 2 months all the skin on my body peeled off despite being on high level steroids and it also caused me to have a fast heart rate and feel nervous/irritable and shaky and have very dry eyes and high eye pressure. BEcause of being on high level steroids I have experienced very bad side effects such as infections/moon face/weight gain, etc. all that comes with prednisone. The allergic reaction also triggered a lupus flare. The whole reason I started on this medicine was to reduce the amount of prednisone I was taking. This medicine has caused me months of suffering and thousands in medical b F 25 14 days
200 mg 2X day
9/12/2011
 5  Primary Sjogrins I believe I have some thinning of hair. I have photosensativity (which is really bothering me as it is summer and I am outdoors a lot), but I had photosensativity prior to taking the drug. I am not sure of the MG dosage I take as I do not have the container available as I type this. I am on the generic form of plaquenil; it kicked in within two weeks while I was away on vacation...I thought, at the time, that it was the climate that made me feel soooo much better. When I returned home and still felt better (and still do), I realized it was the drug. I have had my disease since I was a teenager, so I am well into the symptoms at age 63. With the drug I do not have the joint pain, and just feel better generally. It has made a big difference in my life, and I hope I can continue on it. F 63 6 months
200 2X day
9/8/2011
 3  Mixed connective tissue disease This medication helped with the symptoms of the disease, but caused nasea, vomiting, forgetfulness, blurry vision, hypokelemia, and I was recently took off the med cuz it caused my EKG to have borderline qt prolongation. F 19 4 years
200 1X day
9/2/2011
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 5  suspected lupus due to celiac disea no side effects/and many celiac lupus symptoms such as hair loss, ringing in ears, facial pain and rash, digestive issues and fatigue and severe pain are so much better after 1 week. I had lost 30 lbs in 3 weeks and am starting to put weight back on. Also awake almost too much in comparison. Am told results can take awhile, if I continue to feel better am thinking I may someday feel like normal again. Still have very dry eyes, mouth and skin-but had that before rx. I have been off work for 2 months and was fearing there was no solution. Everyone reading this research celiac-it is usually the original root for all of these diseases and so many more. Left untreated ie: not changing diet-most often leads to CANCERS. No one tells you this...insist to get tested for celiac! F 49 1 weeks
200 mg 2X day
8/31/2011
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 3  lupus and sjogrens short term memory loss and have become increasingly short tempered. Bruises EVERYWHERE. Consultant Rheumy asked me to stop taking it today. Called Sanofi helpline and am waiting for them to return call to let me know if this is usual F 40 4 months
200mg 1X day
8/25/2011
 3  Sjogren's terrilbe itching back of scalp. Recent very red patch across back of neck. Anxiety. Feeling of malaise. Forgetful, I don't know if that problem is from this medication. Can't take too much noise, feel extremely stressed, tired. I have been having what my doctor calls episodic flare up of Sjogren's. I have had itchy scalp for the longest, Rheumo says very likely the medication. I was taking 100mg x2 daily, he told me to cut second dose in half. My itching getting worse, and my scalp itched and burns. Some itching front of scalp, stomach, but the back of scalp is terrible and really red in neck area. The medication has always helped my symptoms, it's depressing that this is happening. Going for blood work. 51 1 years
100/50 2X day
8/1/2011
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 4  unspecified connective tissue disea Nausea, upset stomach. Anxiety, nervousness, it is hard to tell the cause for that. Skin pigmentation, hair loss. I feel some tremors, specially in the head. Even with all this it is much less side effects than prednisone. Plaquenil helped with my shoulder pain and definitively with the headache I used to have on a daily basis. My sed rate is going down and that is why I started taking it on the first place. Also, I don't have any more malar rash after sun exposure. F 48 5 months
30 mg 1X day
7/26/2011
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 1  inflammatory arthritis plaquenil toxicity resulting in scotomas (rings) in both eyes I had yearly eye exams by an opthamologist, but never had a visual field test until I complained about not being able to find the cursor on my computer, and then failing the color-dot test. The Dr. also had skipped a year on the color test so said my problem could have been developing for over two years. Six months before my eye appointment, I starting seeing black and white flashes when I closed my eyes at bedtime, but it was only for a few minutes and didn't hurt. I thought it was related to stress headaches I'd been having. My advice if you take plaquenil is to tell your eye dr. immediately of any type of change related to your eyes/vision. I stopped taking plaquenil as soon as I failed my first color test. It has been five months and my vision continues to get worse. I am now trying accupuncture for the inflammation and pain associated with rheumatoid arthritis and would recommend people try that as an alternative. (I still take relafen and tylenol and use lidoderm patches) F 56 5 years
30 MG 2X day
7/17/2011
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 5  Lupus and Sjogrens I've really not had any side-effect except maybe less appetite the first week, and maybe a little depression for a day or two. But nothing big. I think it's a miracle drug and I feel 20 years younger. I love Plaquenil. It started to go to work at about 2 weeks, and one by one my joints stopped hurting. My legs stopped hurting; my eyes cleared up from Sjorgren's. Now I have more energy and I feel more "normal" than I have for 20 years. Plaquenil is a MiracleDrug as far as I'm concerned. The first couple days I had little appetite, and was a tad depressed for 2 days but that passed quickly. No bad reactions and I feel better now than I have in years. F 65 90 days
200mg BID 2X day
7/11/2011
 1  Mixed connective tissue disease I started the medication 16 days ago @ 200mg once a day. 5 days ago I increased the dose to 200mg twice a day. On day 15 small red spots appeared on my nose and forehead and today on day 16 I am covered in them. I have discontinued Plaquenil to see if it will clear up. F 40 15 days
200mg 2X day
7/11/2011
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 5  Arthralgia I just recently started feeling depressed and angry.. But then again it just could be because my husband is being an inconsiderate drunk... It's greatly eased my pain and swelling and my energy level went up to 90%.. it's a miracle drug !.!.! Thank you ;) F 33 10 months
100 2X day
6/27/2011
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 3  RA I've had a lot of issues with anxiety and moodiness but now take one half on klonopin (sp?) if I wake up "on the wrong side of the bed"... Not sure of dosage... I have had some improvement but now it seems to have plateaued for the last 2.5 months.. Frustrated as my husband would prefer we not get pregnant while I'm on the meds .. Really hoping something is going to change. Also dizziness F 35 5 months
200Mg 2X day
6/20/2011
 1  RA M 60
100mg 1X day
6/10/2011
Patient History
 2  dermatomyasitis after 3 days rash on whole body and itchy,radiating burning heat , redness intensified. went off after 21 days, my GP said it was allergic reaction, took atarx for last 12 days it's helping alot. Rheum said not likely a drug reaction that I should stay on it. I may try it again after a few more weeks . F 56 21 days
200 1X day
5/29/2011
 5  for hand and feet pain None that i noticed It is not supposed to help my condition(small tissue neuropathy) but i started taking it bacause i was misdiagnosed for arthritis and nothing worked.When a neurologist figured it out it was neuropathy he said to start Gabapentin which i did and it helped.later the neurologist and rhemotologist said to stop placquenil.After 6 weeks off the Placquenil my discomfort got a little worse so i just went back on it for a 3 month trial. i am still taking the Gabapentin M 65 10 weeks
100MG 1X day
5/26/2011
 1  Psoriatic arthritis Severe depression and anxiety, diarrhea daily, sore mouth and tongue the pain in my joints was greatly improved but I can not trade that for depression! I wish I could have stayed on it but I stopped it 3 days ago and still feel nervous and not well. F 51 5 weeks
200 mg. 2X day
5/26/2011

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