PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  UCTD (Synovitis) & Sjogren's Increased nerve pain. Tingling up the back of my skull and servere nerve pain in my ribs and chest and back. I was even hospitalized and all of my doctors never associated this nerve pain with the Plaquenil, probably because it is an uncommon side effect. After 1 month I broke out in a rash, stopped taking it for a month until it went away then back on it for a month. Plaquenil helped me greatly so I was sad to have to go off of it. Took away chronic,dull,deep tendon and bursa pain in my legs and arms. Lost 13 pounds in 2 months. Helped with my autonomic dysfunction (sweating episodes) and helped with gritty eyes from Sjogren's. F 32 2 months
200 mg 2X day
1/25/2011
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 4  Lupus and sjogren's Itching in hands and feet when first started taking it, hair loss after about 3 months of taking it, headaches when I forget to take it I take the generic brand and it has really helped me with all my symptoms of lupus and sjogren's!! In the beginning my hands and feet itches to the point where I would start crying and couldn't sleep but that went away after the first couple of weeks and inhale never had that problem again. My hair was thinning for a couple of months but has now stopped but my hair is a lot thinner :( and when I forget to take it I can tell because I will start to not feel good! Overall this drug saved my life and gives me to do whatever I want with all my symptoms of my diseases under control !! I would recommend it, thank you plaquenil for letting me be just another teenager like all my friends!! F 17 10 months
300 mg 1X day
1/20/2011
 3  Lupus Pernio gassy, some upset stomach,some fatigue the first few days, some acne??? I can handle the first few side effects but the acne not so much...if anyone else has experienced acne please let me know if yours went away with continued use of the drug...hopefully soon! F 41 9 days
100mg 1X day
1/12/2011
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 3  Discoid lupus I've been on this med for two months. Started at 400 mg per day. First few days felt terrific. Now developed itchy upper arms. Really can't tell what's the drug is doing. I'm still getting lesions on my forearms and I still bruise easily. Hair appears to be growing back. I am much more wide awake on the drug and sleeping is difficult even though the dreams are very interesting. I have discoid on my arms and sometimes legs but arms are the worst. Hope this drug stops any further development of the disease. I used to get stiff knees from walking but not so much now. Have a lot of nasal congestion but can't tell if it's related to the drug. M 57 60 days
200 mg 2X day
12/7/2010
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 1  sjogren I was in a severe depression. I even couldnīt get to my work.. I was crying nearly the whole day. So out of the blue. I was also very anxious, nervous. So not me anymore. I quit this medication. Although, I felt a difference. It worked very well for my fatique, aches in my muscles. But the pain in my fingers en wrists was still there. The effects of this medication was for me more worse than my sjogren symptoms. I am Dutch and overhere they all think that the depression comes from their disseaseīs. Well, I defintely think its de Plaquenil. F 44 6 weeks
400 2X day
12/5/2010
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 3  UCTD 2009 I start experiencing lots of bruising marks on legs and arms, quite embarrassing. I have not found anything to cover the marks. I did not know it was a side effect of plaquenil until my doctor told me. F 51 6 years
200 mg 2X day
11/25/2010
 5  Sjogrens Gassy. But much better than i was. Nervous about the eyes. Generic gave me eye aches. REAL Plaquinel hasn't. Still have to get eyes checked. Hope I can keep taking this. There aren't many alternatives and this seems to be doing okay .. so far. F 48 3 months
200 mg 2X day
10/27/2010
 4  uctd and sjorgrens slight metalic taste in my mouth. At first, some dizziness which went away in a few weeks. Some needed weight loss - 5 lbs. in 2 months. Have felt much better on Plaq. - more energy, less fatigue. My joints ache much less. my dry eyes,mouth, ears continue though.My rashes have improved. F 63 2 months
200mg 1X day
10/27/2010
 4  Lyme - lyme artrosis Gas.... I noticed vivid dreams, no problem, I like it. Bit lightness in the head perhaps... We will see coming months. I read all about Plaquenil on this forum, and I'm very thankfull to you for all your input. The plaquenil was taken shortly after the meal 2 times a day 200 mg. I also use Doxycyline 4 x 100 mg/day. It seems to start working just after an hour or so after the FIRST dose... (placebo-effect???) Now, after 3 days, I'm free of hip and back (lumbal- low spine) pain. I realize it's not over yet, I will continue using this combination for about 3-4 months. I bought my Sanofi-Aventis plaquenil at Goldpharma.com, because no doctor in the Netherlands believe in Lyme desease... (except 1, Dr. Kingma of the Walborg Oosteneinde clinique in Amsterdam. We live in a country with a hoplessly outdated medical culture. M 47
200 1X day
10/18/2010
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Patient History
 3  rheumatoid arthritis hair loss, bruised easily (initially), explosive diarrhea about 3 hours after dose, thinning skin, very itchy rash on back and torso (has eased in last week or so), bloating has eased the pain enough that I can sleep (when I am not scratching); looked into other drugs but the possible side effects are even worse, so I guess I will stick it out for awhile F 52 6 weeks
200 mg 1X day
10/14/2010
 4  non specific auto immune disease none I have been taking it along with 100mg of Imuran for almost 2 years. I have noticed a significant help with my arthritic type symptoms. F 29 2 years
200mg 1X day
10/9/2010
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 2  Lupus Woke up with itchy, red rash all over my chest and stomach after nine days of Plaquenil. Spread to back the next day and then legs and arms. Significant rash lasted two weeks where itchiness was enough to keep me awake two to three hours every night. After that, has turned into very faint rash that doesn't itch, but got dry scaly, krinkly skin. Dermatologist said this not uncommon after medicine rash and can last weeks. Curel cream is helping. Stopped taking Plaquenil when got the allergic reaction after nine days. Rheumatologist is lowering the dosage of Prednisone over a longer period of time since cannot take Plaquenil to "kick in" as the long term replacement. I have good energy and no joint pains at 7.5 mg Prednisone. Went down to 5 mg today for the next three weeks. We are hoping for no flare up. F 57 9 days
300 mg 1X day
9/25/2010
 5  arthritus My first medication was prednesilone which while it worked ok it had side effects. My testes shrank to the size of grapes and I gained 20kg of weight, this went on to cause heart disease. Plaquenil has worked really well with only some itching when I first started taking it. Now I have concerns that I am experiencing muscle weakness and tremors particularly in my right arm M 55 3 years
20 2X day
9/16/2010
 3  Sjogren's Made me itch a little. Made my scalp feel sunburned though I was not out in the sun. Unfortunately after 3 weeks developed rash on upper body and shins/ankles. I wanted this to work so I'm bummed I developed an allergy. In the short time I took it, it actually helped my IC/PBS alot which sometimes goes along with sjogren's. F 48 3 weeks
100mg 1X day
9/15/2010
 5  SLE None- a lot of the "side effects" I've noticed others speaking of seem to be symptoms of connective tissue disease It took about 3-4 months, but I feel like a completely different person. I still have some occasional issues, but nothing severe or that I am unable to deal with. I take the med at night and can only say that it has greatly improved my quality of life. F 41 2 years
400 mg 1X day
9/5/2010
 1  RA Bullseye maculopothy. I've lost most of my central vision in both eyes. I experienced white flashes which my ophthalmologist dismissed. Within a few months, the blindness occurred suddenly. I had retinal examinations twice a year. I have good peripheral vision, a large doughnut shape of no vision, and a tiny area of poor central vision. Blindness stinks. This drug was not worth this. F 54 12 years
200 mg 2X day
9/5/2010
 5  RA and Sjogrens low white blood cell count I absolutely loved Plaquenil. I had saliva and the swelling in my joints was gone. I started to exercise again. I had no other side effects except it caused by WBC count to plummet and my rheumy had to give up on it. Now its onto MTX and I resent it. I wish I could stay on the Plaquenil. F 43 11 months
200mg 1X day
8/17/2010
 4  Sjogren's Syndrome, then Lupus Stomach upset & lightheaded the first day. Just take it after a meal and no more stomach trouble. Ringing in the ears, which I can tolerate. I do get yearly eye exams, but have had no sign of build up in my retinas. Advised by bloggers on health boards to take only name brand Plaquenil(no generics) from the beginning & so avoided any allergic reactions or rashes. I have to pay extra since insurance won't pay for all of the name brand price, & the doctor has to authorize on the script that I can only take name brand Plaquenil, but it is worth it! I have much less fatigue and pain. This med works well for me! F 56 4 years
200 1X day
8/11/2010
 5  SLE No side effects ever. I was in complete remission 10 years ago and when my MD decreased my Plaquenil to once a day I went into a flare up and have not gone back into remission even when he put the Plaquenil back up to twice a day, added prednisone, added imuran. F 48 22 years
30 2X day
8/6/2010
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 5  UCTD No side effects so far (maybe a little gassy at first but that is inconsequential as far as I'm concerned). Plaquenil (the generic) has given me my life back. I could not tolerate the first drug prescribed for UCTD (one dose and my eye started swelling). With Plaquenil the pain is almost gone but most importantly the fatigue has subsided immensely. My personality is back to where it was before the UCTD started taking over my life. I just hope the side effects stay away and that my 6-month eye check-ups reveal no change because as far as I'm concerned this is a wonder drug. F 59 8 weeks
200 2X day
8/3/2010

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