PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Lupus/Rheumatoid Arthritis This has been a miracle drug for me. At age 16 I was unable to get out of bed due to pain and fatigue. After a month of taking plaquenil 400 mg. each morning I slowly improved. I had no hives or allergic reactions. My vision has grown increasingly blurry and I have noticed this fluctuates depending on how stressed or tired I am. I am 25 now and have to wear 1.75 strength reader glasses, and anticipate having to wear glasses daily within the next decade, but this side-effect is worth it considering how helpful Plaquenil has been for me. I read a lot of the reviews from other patients and my sympathies go out to all of you. We all know our bodies are very sensitive, so I would not write off this drug, it really does work miracles for some people. I have found that high doses of Vitamin D (5000 I.U. every day for 2 weeks) and high doses of buffered Vitamin C (1000 mg. every 2-4 hours) has really helped my inflammation and well being. Good luck to you all. F 25 9 years
400 1X day
6/30/2012
 5  Ray's, Fibro and undiagnosed Extreme stomache cramps and some confusion but overall starting on 100mg and increasing to 400mg after 3 days, I've been feeling better and better since day one! F 34 9 days
400
6/28/2012
 4  probable sjogren's some GI discomfort initially, but it went away. itchy rash on trunk for around 2 weeks before it went away. sun sensitivity. some mood issues, but mild. initially some wild dreams. took a few weeks to feel effects, and then i swore i'd NEVER quit taking the drug - my joint pain left and my energy returned. doc mentioned decreasing the dosage and i gradually left off one dose/day, but had a flare up and returned to full dosage. the second time my energy returned, but still some joint pain, particularly in elbows, wrists, hands. also fairly photosensitive. F 61 7 months
200 mg 2X day
6/24/2012
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 1  Fibromyalgia/lyme/bartonella took the edge off my pain but doctor never told me about eye problems. Tons of eye problems that have not gone away even though I've been off Plaquenil for some years!! About 9 months after starting Plaquenil, started having vision issues, difficult to explain. Couldn't see or focus on fast moving objects, blurred, like a thick film over my eyes. Could see a fast moving ball in maybe three spots on its trajectory but otherwise blurred. Difficulty reading, same kind of film sensation over my eyes. Symptoms have not improved. Eye tests don't show much of anything...some pigmentation dislodging and loss. Not getting better at all. Would not have taken Plaquenil if had known about visual effects but doctor never told me. M 44 4 years
? 2X day
6/19/2012
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 2  SLE lupus I have been on plaquenil for 4 yrs at first it seemed to help with the joint pain & fatigue & i am a lover of the great outdoors, horseback riding, gardening, ect. But know am having serious gastro, bowel, (afraid to leave my home for fear of accident)headaches, severe depression, spoke w/dr. We will now discontinue the plaquenil and start benlysta. Have taken it before it did not seem to be as effective for the pain, but did help w/other symptoms. Was at least able to have a social and active life again. One other note my eye site was always blurred after taking the plaquinel as well. Never could get good eye exams and have glasses that are the correct strength. F 50 1 years
2x d
6/16/2012
 4  RA No side effects whatsoever at first. A few weeks after I went down to 1 a day I noticed floaters in my eyes. Didn't make the connection until about a week later that they were caused as a side effect from medicine. Love this drug. Besides the eye effects, I would much rather have it then the pain & stiffness of RA. I will continue to get eye exams every 6 months, so far so good on my eye exams. I usually only take this medicince half the year, when needed. F 36 10 days
200mg 2X day
4/17/2012
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 2  RA headache,nausea,extreme gastrointestinal upset, muscle cramps and frequent copious nocturnal urination (anyone else?) I have had severe arthritis symptoms for about a year now. Initially treated with a combo of NSAIDS and prednisone, I experienced great relief. As time went on these meds stopped working and Enbrel was added...finally plaquenil was prescribed to enhance the others meds..I feel like with each pill I am taking poison..I've never had a medication affect me so profoundly..with each dose I am more sickly than the day before..after reading the reports of others, I can't help but have severe reservations about continuing this medication..considering living with a higher acceptable level of pain vs unbearable nausea...I have temporarily stopped taking it until I consult MD F 51 8 days
200MG 2X day
4/1/2012
 5  Sjogrens and Lupus Its wonderful. Only symptoms were the first 2 or 3 days I was a bit depressed. My appetite is a LOT less but then I needed to lose some weight. But after that, I felt better and better. Its been a miracle drug for me. My eyes stopped being dry; mouth no longer dry either. Increased energy; better spirits. My joints only hurt a little now so I take some tramadol. Overall, It's a miracle drug for me. I love it and I don't know what I would have done over the last 6 months without it. It saved my life. F 65 6 months
200mg 2X day
3/26/2012
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 2  ??? +ANA/possible SLE or MCTD ?? Headaches daily, fatigue, weakness, flatulence, depressed 1st week with anxiety, generally ill-feeling. F 36 3 weeks
400mg 1x/d
3/21/2012
 3  SLE On the original dosage I was suffering from chronic diarrhea and hair loss within two weeks. Second time around (with 200 mg taken at morning and night 4 days a week) these have taken longer to kick in. Have started to experience a lack of motivation and feel like I am not quite connected to the world. I am also quite anxious for large parts of the day and having never been a big sleeper I am sleeping even less which isn't helping me cope with anything else Am relieved that I am not going mad with respect to the anxiety and the insomnia, but I agree that the benefits even after such a short space in time have been worth it already. F 46 28 days
200-400mg 1X day
3/17/2012
 4  SLE Lupus First two weeks had minor nausea and some bloating. I have major IBS so I didn't even realize it was from the drug until looking back on it later. I have noticed a bit more occasional IBS symptoms depending on what I eat since being on it but really not much worse than I have been in the past. Wholistic stuff and Prilosec helps with that and again, I have always had major stomach issues plus I take a ton of other stuff for sezuries since the Lupus is in my central nervous system. Other than that no side effects and I am a side effect type of gal. Before the drug I was non-functioning. Couldn't work, couldn't spend time with my family and I had no life. After three months I started to notice some energy returning. After 6 months I was hiking again. Now the initial big energy boost didn't last. The Lupus flares did return but overall I would saw I am better on Plaquenil than off. Lupus still sucks big time and it is always up and down but I wouldn't be funtioning without Plaquenil. F 37 18 months
400mg 1X day
3/14/2012
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 5  SLE Stomach sensitivity, doctor told me to take Prilosec which helped. I use to be on Prednisone for 3 years and it helped in the beginning but later I was in a lot of pain. Plaquenil is like a miracle drug! I feel like a different person, today i can run, go to the beach, and stay very active (the sun doesn't bother me) and had consistently perfect blood work in the last year. F 34 2.5 years
200mg 1X day
3/10/2012
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 3  Rheumatoid Arthritis Flatulence, headache, diarrhea, upset stomach UPDATE to my posting on 1/14/2012: I have been on Plaquenil for 7 months now. For the last two weeks I have found that it has reached it's limit on helping my pain and that my joints are constantly stiff and achy. I have been taking Naprosyn 1-2x a day to help the pain, but it is just barely taking the edge off. The upset stomach, flatulence and headache are gone. My rheumotologist is now adding Methotrexate to my regimine, but not taking me off of Plaquenil until she is sure MTX is working, so that I don't lose all of the benefits of the drug and be in more pain. While the medicine worked for the first six months, it was nice being pain free. But not all medications work for everyone. Explore your options before settling on or rejecting a medication. F 29 7 months
200 MG 2X day
3/9/2012
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 2  discoid lupus woke up one morning with severe rashes on back, chest, neck area, and buttucks area, went to see my dermy, and waiting for biopsy to see if allergic to it, or flare up stopped taking it after I noticed the rash, not sure how long if I was allergic to it that the rash will go away F 50 3 weeks
200 1X day
3/9/2012
 4  Sjogrens Syndrome I had rashes on face, neck, inside of elbows, behind knees and all of Sjogrens symptoms. When started taking plaquenil I had crazy dreams at first. After 3 months I feel so much better. My energy is not back 100% but I feel that I can function with my busy teenagers schedules. The rashes are much better and if they start to come back I just use some hydrocortizone lotion in addition. I worry about my eyesite and if it will stop working over time. Have pain in joints during the night if I miss a dose. F 46 3 months
200mg 2X day
3/3/2012
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 1  Lupus and Fibromyalgia After 2 weeks of being on Plaquenil had allergic reaction. Broke out in hives from head to toe, also had to go to emergency room due to face, lips and throat swelling. I was prescribed Prednisone for allergice reaction and also had prednisone injections. Was overdosed on steroids which caused physocisis, mania and terrible heartburn. It has been six weeks since taking plaquenil and still having hives. It has been awful experience F 46 2 weeks
200 mg 1X day
2/28/2012
 1  Inflamatory arthritis Nausea, stomach cramps and diarhea, headache, weight loss, fatigue, general "unwell" feeling. i was on generic plaquenil for a month. Took myself off of it because the side effects were worse than the disease. My rheumatoligist talked me into trying brand name plaquenil last week, saying that possibly it would not affect me as the generic had. After taking it for less than a week, I am having the same problem I had with the generic. Also talked with my opthamologist and decided that the risk to my eyesight was not worth it. Now I'm just trying to get it out of my system so that I don't feel like this. I can cope with the joint pain better than with the side affects caused by this drug. F 65 1 months
200 mg 1X day
2/19/2012
 4  MCTD, Sjogrens, Reynauds, Fibro Occasional nausea, diarrhea, gastro issues, HTN with tachycardia. Nothing that would outweigh the benefits I have experienced. Also got itching on legs that turned into severe ugly bruises about a month into taking meds and then went away until it happened again about a week ago. However I am on a few other meds and cannot say for sure it's the Plaquenil causing this. Seems to be working great for me! I also believe that I feel well due to my positive mind set and the fact that I am very active. I've been at the other end of the spectrum before with negativity and depression and I see a world of difference! Good luck to all of you suffering with auto immune disorders... if Plaquenil isn't working for you I hope you find something that will! F 35 5 months
200 2X day
2/9/2012
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 4  Undifferentiated connective tissue It was tough to start Plaquenil....at twice a day I had hallucinations. However, my rheumatologist encouraged me to stay with once daily dose. It took about 5 months, but one day I realized my joint pain was significantly less and stamina improved. I didn't have another flare for almost a year. Hard, but worth it and all side effects have subsided. F 47 2 years
200mg
2/6/2012
 3  RA & Sjogrens stomach cramping, gas & gas pains, headahes, increased depression & irritability (not sure if this is due to not feeling good or directly from the drug) Not far into treatment yet, but feeling somewhat less achy. However, headaches stomach cramps and mental state are not good. Feel like crying all the time & have no motivation. I used to be a regular runner & self-motivated self-employed person. Just want to feel like 'myself' again...hoping the Plaquenil helps me return to 'normal' after a few more weeks of treatment. Doc said 6-8 wks for results to show. F 38 21 days
200 MG 2X day
1/29/2012

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