PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Anxiety, depression Irritability, flat affect when increased to 100 mg, rage when drinking alcohol I was a very irritable and angry person on this drug. Not myself at all. I would get so angry over stupid things that were not worth getting upset about. I have been off of drug for 2 weeks and I am a new person that is happy. When I started tapering off my meds I had dizziness, nausea , mild headache. No brain zaps. So glad I got off drug, I feel better overall. F 29 2 years
50 mg
5/3/2015
 1  severe anxiety and depression, PTSD Over the years I've suffered from depression and anxiety. I've been on several different medications. Pristiq has made me very paranoid, restless, and agitated. I have lost all interest in activities. I spent most of my days in bed afraid to leave the house. Had spliting headaches and insomnia. My eyesight changed for the worse. Extremely fatigued, dizzy, loss of appetite...but experienced weight gain. Very bad side effects in general. Horrible when discontinuing use. Caused neurological issues. F 31 10 months
100
4/23/2015
 3  Depression Moderate constipation, horrible withdrawal symptoms if one dose missed:nausea, blurred vision, headache,violent tendencies, itching all over I started on Pristiq after lexapro quit working,after 7 years.After trying several other drugs with unbearable side effects, this one was great. Missing a dose is a nightmare though. I can't function at all until I take it. I get very sick.Now after being on it a year I've developed itching without a rash. Just itching like crazy. First my scalp then random places on my body.Allergy need help and anxiety or stress make it worse.I am also on generic lamictal for years,but never had that issue before taking Pristiq.I wish I could get off meds, but depression is too scary and powerful in my life.Single mom, need to keep it together.I still struggle emotionally even with meds. F 43 1 years
150 mg
4/8/2015
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 1  Posting on behalf of my father Worsened anxiety Worsened bipolar Extreme detachment Suicidal I am so happy I found this site after seeing what happened to my father (in his 50's). The reviews that come up when one googles this drug seem completely misleading until you dig a bit further. My father was switched from Lexapro to Pristiq for his bipolar when Lexapro stopped working. What happened after a few weeks was enough to scare the whole family and every acquaintance of my fathers. It was like he was a walking zombie with no feelings other than negative and irrational ones and turned verbally aggressive to everyone. His lows were lower than ever, and his manic highs were returning. How can one drug such as lexapro work so well (before tolerance sets in), and pristiq do so much damage. In the end the only choices left were to either have him admitted to get help and commence legal proceedings against the manufacturer, or have him come off willingly. Luckily, after a few devastating incidents caused by his behavior to friends and family - he agreed to come off the drug. Coming off the drug however has posed new problems that never occurred with Lexapro. All that matters is that he has finally listened to the family about his destructive behavior on this drug and we are all slowly working together as a family to get some stability back. I still don't understand the adverse reaction when other antidepressants worked fine for him. I have a really uncomfortable feeling that the true dangers of this drug will not be made public for years until a class action is filed. 54 4 months
150 1X day
4/7/2015
 1  moderate depression Insomnia, loss of labido, nightmares,mood swings, headaches,feelings of insanity. Hated this drug. Early on I felt wide awake to the point where it felt like my eyes could not open any wider if I tried, and only couple hrs sleep. Horrible vivid nightmares that I would think about most of the following day. Totally negative impact on my mild depression.i advise to avoid!!! M 42 6 weeks
50mg
4/3/2015
 5  Depression,bipolar Wonderful saved my life F 53 1 days
50
3/5/2015
 5  Bipolar Spacey head spins if a dose is missed. I found this to be extremely effective with the depressive side of bipolar and when used in conjunction with Epilim it appears to be keeping me quite stable. F 44 6 months
25
3/1/2015
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 5  Depression, endogenous Basically none. I had been on Zoloft for two years and its effects seemed to be waning. My physician switched me to Pristiq and I felt much better. I have been doing so well that we are about to take me off, slowly. You cannot be addicted to this medication, and will not experience withdrawl after going off of it--but will likely have some discontinuance side effects. Oh, and reading some of the other reviews--people remember that alot of reviewers have issues in life BEYOND the medication thay are taking. F 58 1 days
50 mg 1X day
2/23/2015
 1  depression Withdrawal effects are absolutely awful. The worst I've ever experienced. I get such anxiety when I realize I forgot to take it because I know I'm going to be so sick. Dizziness, vertigo, nausea. The only way to get rid of it is to take it and sleep for a few hours. F 22 3 years
100mg
2/16/2015
 5  major depression disorder I lost 25 lbs. I am 5'1". I used to weigh 130lbs. Now 105 lbs. Helped me with my depression alot. I would highly recommend this medication. But like all medications they all work differently for everyone. At first u might have some side effects like dizziness or sleepy but if u hang in there it should be very helpful. F 33 3 years
50 mg
2/13/2015
 1  PTSD depression Lack of sex drive, aching bones , headaches , blurry vision , loss of balance, irritable Taking pristiq has been the biggest mistake Ive ever made if I miss just one day I will begin to feel that my brain is floating in my head! Sorta of feels like electric zaps in my head that makes me get blurry vision splitting headache I have tried to come off pristiq slowly and I ended up in hospital I feel like a druggie I can't live with out it :( F 27 2 years
50mg
2/5/2015
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 1  Mild anxiety Lack of caring, compulsive gambling, angry outbursts, gastrointestinal problems, high blood pressure, not able to see what I was doing wrong, only able to see how I felt and not others. Pristiq ruined my marriage. My wife tried to tell me for years this drug changed my behavior and for some reason I couldn't see how really wrong the things I was doing were. Even other family members could see my behavior had changed dramatically but I was addicted and thought I couldn't live without it. M 44 3 years
50 1X day
2/4/2015
 4  depression anxiety bad thoughts Nausea, headache, nervous I have tried many antidepressants over the past couple years & had allergic reactions to all of them. Most putting me into the hosputal. With pristiq I have been able to concentrate & have more energy to be motivated to get up & do my normal routine. I was so nervous because I was so exhausted with the side effects that I didn't want to try a new medication again. But once I got over the fear, I feel much better so far. Not euphoric but, able to go about my day without so much worry & anxiety. Medicine doesn't cure everything but, I have learned many coping mechanisma to help as well. I hope my insight has helped. I have ocd tendencies & now I am not trying to be so perfect besides a few things since I am a mother. Before I was unable to have enough energy to keep up with my 2 year old. Now I can & hope that I can get back to normal, if there is such a thing. Just don't give up. F 28 6 days
2/3/2015
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 4  depression/anxiety While taking medication: itchy skin, constipation, jaw clenching, slightly foggy brain sometimes, and no sex drive. When I miss a dose: whenever I miss 1 day, I get a bad headache, nausea, crying for no reason and dizziness. When I had to miss 2 days due to prescription problems, I had all of that except my dizziness and vertigo were extremely bad! I didn't feel safe driving and every time I moved I was so dizzy I felt like I might fall over. Overall when I take my medicine I feel great! It has definitely helped with my depression and anxiety. However, when I don't take it, I feel like crap! I am honestly scared for when I do decide to stop using this medicine because I know that the withdrawal will be the worst. I am looking at others' responses to see different ways that people got off of pristiq to see ways to help with the withdrawal side effects. Definitely do not go cold turkey! F 22 2 months
50 mg
1/30/2015
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 2  Depression Low appetite, no sex drive, lethargy, blackouts, nervousness, mood swings While taking pristiq I have been getting blackouts once I have alcohol. The first time was only a short experience and I was safe. The second time I missed two hours of my life where I did something very dangerous. I'm coherent and functional but I remember nothing. Has anyone else had this problem? F 22 1 months
100
1/26/2015
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 3  MDD & anxiety Had a somewhat positive experience but after a month developed severe itching & hives. Thought it was anxiety. After a few months ruling out any changes in my life & the hives & itching became intolerable went to urgent care. They took me off. Itching is subsiding but withdrawl is not so great. Also did I mention had extreme sexual dysfunction:) F 45 4 months
50mg
1/25/2015
 1  Depression Insomnia, anxiety, fear, numbness, aching bones. This was made by Wyeth after Effexor had a generic. Do not take this drug as you will never be able to quit without severe withdrawals. Horrible experience. I feel numb not myself and want to taper off but fear the process after reading others comments. I don't want to do anything I am completely a zombie. F 54 4 months
100 1X day
1/25/2015
 5  Depression and anxiety Idc. It saved my life! If you get a mouth swab, it will tell you what meds your body will process most effectively. I have tried all antidep, but my body responds the best to SNRIs. F 45 7 years
100 mg
1/13/2015
 5  Depression Best med out there in my opinion. Tried celexa, wellbutrin, and viibryd. Little to no side effects with Pristiq. Gives motivation and drive to push forward and look toward a productive future. Would really recommend this medication. M 38 1 years
50
1/10/2015
 4  Depression anxiety The pill has helped with my depression if I miss one dose within 24 hours I'm so dizzy headed and lightheaded I can't function I have a headache. And my depression is just awful crying for no reason. I have absolutely no sex drive. After saying all that I was so depressed I was on the verge of suicide it's help with that. F 39 10 months
50mg
1/9/2015
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