PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression / Anxiety Extreme nausea for the first 3 days, constipation for the first week, vivid dreams, increased libido but inability to reach orgasm, slight decrease in appetite, heavy bleeding and clots during menstruation, withdrawal symptoms (shivering, mood swings, dizziness, nausea) with two missed doses Pristiq (100 mg) is my first antidepressant. I have been taking it for only a short while but feel that it's been helpful so far. I've noticed that I am more motivated and more impulsive. When I wake up in the morning I don't have to talk myself into getting out of bed and immediately start my daily tasks. But the side effects are hard to ignore. I am most concerned with the increased bleeding during my period, which was once very predictable. I did not attribute the change to Pristiq at first but read online comments from at least three other women after it became a recurring problem. I am going to talk to my doctor about this side effect which I could find very little information about and will hopefully be provided with some helpful answers. F 21 3 months
11/17/2009
 3  Depression I have tried many anti-deps over the last 12 years , I'm hoping this one will really help turn things around. My complaints so far ( ive been on it about 7 days) VERY blurred vision, stomach ache. F 42 7 days
11/17/2009
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 3  anxiety/depression/panic attacks NAUSEA -I am nauseated 80% of the day- I have tried Prozac, Effexor, Paxil, Seroquel (out of it all day) Zoloft, Cymbalta (hallucinations) Lexapro (weight gain and extreme paranoia), Geodon (night sweats and vivid dreams), Buspar, Wellbutrtin, Vistaril, Neurontin, Xanax...the only thing that helps with the anxiety the way that I would like it to was the xanax, but my current doctor will not prescribe it- I have had bad enough side effects with all of these (esp Lexapro) that I have started another one- Pristiq seems to be working to a minimum, although I have only been taking it for about a week. The nausea is something I have never had a prob with on any med, so it is highly annoying. I will keep it up though. I have been bulimic for nearly 17 years, and the good thing about this drug is that it doesnt make me hungry so I am no triggered in that sense. I dont know what to think with anything. I have been agitated and suffer extreme social phobia and have been in therapy for a few years. I just want the anxiety to ease up a little bit and nothing seems to work for very long, or the side effects just get the best of me. I have heard nothing but good things about this med, so I have a good feeling that it may benefit me in some way. Like I said, my anxiety has taken over my life, and I feel like I am not me most of the time. I just want some relief. F 32 1 weeks
11/17/2009
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 1  Depression My husband took this for a week and then went into a state of mania; he couldn't stop moving,had muscle tremors, couldn't sleep; had hallucinations; extreme sleep walking and talking all night long in an unconscious state; he then got into my car and took out the headlight M 38 9 days
11/17/2009
 3  depression; menopause dizziness and nausea, sweats,dry mouth -- not good to combine with alcohol -- weird dreams...did make my depression better... F 52 3 weeks
11/15/2009
 3  Emotional disorders/Depression Hard to fall and stay asleep; awoke 2-3 times per night as if someone turned a switch on on me. Discontinued it, it got worse than before. Dizziness in its prime form. Pristiq generally helped me stay in emotional balance; well, somehow. It has/had an effect of a box ring. My evil and bad are in diagonal corners ready to start a fight and Pristique keeps them in their corners. It doesn't eliminate them, it just delays or cancels the fight. Nice. However, I am afraid of becoming dependent on this drug. So, I discontinued taking it while having my period (thinking I am on safe ground for a few days or so). Oh, my God! First day I got so dizzy, that I fell on the floor and had to stay there for a while until the Earth was safe to walk on it again. Completely dizzy, not like a hang-over dizzy, but like you feel the gravitation and need to hold on to something. I was standing up only so I can throw up and then was lying on the floor again. At work, in my office. Today is the 4th day and I am still dizzy. However, I had a cafe latte to center myself somehow and be able to perform my tasks at work (haven't had coffee in 2 years). And I cried a river - all these 3 days; can't stop from crying. The evil jumps from the corner and makes me say mean things to my child (I called her Stupid - for the first time). so, Pristiq? I don't know. It does something terrible to my brain. And I need my brain for another 3 or 4 decades. F 40 23 days
11/12/2009
 1  Depression Major side effect was my severe mood changes. Found myself getting angry for no real reason. Screaming at my children scared them and myself. I am talking about total rage. Have taken myself off Pristiq and returned to Effexor. Had no problems with that. My children might learn to trust me again. F 43 5 weeks
11/12/2009
 1  Depression/Anxiety Headaches, weight gain, nightsweats, swollen face and hands, increased depression, jaw clenching- teeth grinding, extreme moodiness. I've been on several different antidepressants and still have not found the right one. I plan to discontinue the Pristiq as soon as possible. I am having lots of trouble losing weight, I am very moody and not any less depressed. I cannot wear my wedding ring due to the swollen hands. I have incredible heartburn. I am drenched in night sweats every night and clench my jaw so bad that I have migraines the next day. Not worth it at all to me, time to try something new. F 31 6 months
11/12/2009
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 2  Depression clenched jaw, when asleep and awake. irritability escalating to anger for little or no reason, insomnia. Coming straight off lexapro (it had little effect on me anymore) I tried pristiq for a month. I had headaches from clenching my jaw all the time, which i constantly had to remind myself not to do. I snapped, when before i never did. I was often angry for no reason whatsoever. The insomnia wasn't bad, where on lexapro i could have slept all day and night, i got more done on pristiq. But coffee would have had the same effect on me. This drug appears to be different for everyone. F 21 4 weeks
11/9/2009
 5  depression/anxiety/mood swings First 3 days, i experienced , euphoria, sleepless nights, palpitations, upset stomach, blurred vision, after that, everything gradually went away, and besides some muscle soreness every now and then, this drug has pretty much turned things around for me in a very good way! M 42 14 days
11/4/2009
 4  Depression Ringing ears, loss of appetite, inability to orgasm, sweats While this medication does knock my depression down, the side effects are a little disconcerting... I have noticed if I miss a few days my sexual function is restored without the head zaps and mood swings of withdrawal, my appetite returned, and the ringing stopped. I lave lost weight while on it, which has improved my mindset, so thats a positive in my book.. M 45 2 months
11/4/2009
 1  Depression Good for my depression but side effects were bad. I started having severe leg cramps, heart pounding and heart rate jumping up to 120 from 70 beats several times a day, hand and facial swelling and dry cough. Fatigue. Up to bathroom 6-7 times a night (usually up 1-2 times a night). I quit taking this med after 5 weeks before I had a heart attack! F 49 5 weeks
11/1/2009
 5  severe depression and anxiety none Have been on Pristiq for one year now. First 50 mg, now 100 mg. Best antidepressant ever been on - have been Rx'd most of the common ones over 20 years. On Pristiq I do not get to the bottom of my depression and don't cry all the time. Feel like problems are still present, but am able to deal with them better now. Example: suffer from lonliness but am better able to cope with being with myself alone and more interest in other things. don't dwell on it so much anymore. Love Pristiq!!! F 64 12 months
10/29/2009
 4  Depression & Anxiety Perpetual Nausea, cloudy head, sudden weight loss, disinterest in food. While I'm happy with how my mood is stabilized and depression is now at a functioning and treatable level, I'm worried about the weight loss. In less than a month I've lost 7% of my body weight. I think this is primarily due to my nausea while taking this medication and I'm hoping it will eventually go away and my weight will stabilize again. While it's nice to drop a few pounds, this seems extreme to me. F 27 4 weeks
10/26/2009
 1  Depression Pupils were huge, headache, fevor, severe diaherrea, insomnia Vision was blurry, sunlight hurt my eyes and head. I was very excited to try this new drug but after spending all weekend in bathroom and blurry vision i decided this drug was not for me. I am supprised there are not more comments about dialated pupils as a side effect. I noticed this the 2nd day of taking this awful drug. M 38 2 weeks
10/26/2009
 3  anxiety Nausea, dry mouth, gas, insomnia, decreased appetite/weight loss, possible heart palpitations The first 5 days, I had mild nausea which got better daily. By the 5th day or so, it was gone. I can't sleep for more than 4 hours a night; thinking about taking it in the morning instead of at night. Dry mouth (forcing me to drink more water; not a bad thing). Decreased appetite/weight loss - I'm starving at dinner time, but can only eat about half of my food - not an altogether bad thing. Also wake up with sever hunger pangs. Burping and gas getting better with time. My heart goes into overdrive after I eat dinner, but I was having this problem before the medicine (just seems more pronounced now). F 33 8 days
10/24/2009
 2  Depression Unmotivated, bored, sleepy, weight gain, mentally numb I have taken 50mg of Pristiq daily for about 4 months to treat my depression. I'm depressed. Furthermore, side effects such as apathy (I just don't feel like doing anything while on Pristiq!), weight gain (23 pounds in approximately 4 months), lack of reaching orgasm, and constant fatigue (after 3-4 hours of ingestion) are unworhty of further taking Pristiq. I've decided to slowly discontinue it. M 28 4 months
10/21/2009
 2  GAD, Generalized Anxiety Disorder Excessive thirst, aversion to food, no appetite, physical exhaustion/ constant sleeping, lack of motivation to think or move due to exhaustion. I used to just have anxiety about driving places alone and ect. but now on Pristiq I feel nothing. A total drug induced calm, with no motivation to do anything because I feel like I weigh a thousand pounds and can't lift my body parts. F 21 7 days
10/21/2009
 1  Majjor Depression/BIpolar II, more Sweats have started (feel like in a sauna), head&stomache upset, irratability, weight gain, difficulty falling asleep, general anxiety not relieved, still feel depressed only lessened. Was at 50mg, now 100 mg each nite. Not happy with results. Memory has been effected by depression along with other disorders. I began taking Pristiq when first presented for general distribution to abate depression in majority of the population. F 61 2 years
10/21/2009
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 1  Depression I took this medication for depression. I had a terrible time tolerating 50 mg. of Pristiq. My side effects were leg cramps, memory loss, dizziness, increased depression, head zapping every time I moved my head (this was not present every day - I experienced this on a few different occasions, sometimes lasting up to two days), and a feeling of agitation. I had been on Effexor XR 150 mg. before but experienced some weight gain so my doctor suggested that we switch to Pristiq. Other than the weight gain the Effexor was working well for me. Needless to say I am back on the Effexor as of yesterday. I never write comments but thought it was important to share my negative experience about this drug. My doctor really pushed me to try this and seemed very shocked that I had any side effects. I was relieved to find this site two days ago and to see that I'm not alone. I'm sure this drug will work miracles for some, but it doesn't work for everyone. You just have to keep trying until you find the one that works for you. Good luck! F 45 25 days
10/21/2009

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