PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  depression, anxiety Pristiq seemed to really level me out when I was feeling depressed. I no longer felt suicidal on Pristiq and had no major side effects, but I was experiencing tachycardia. My cardiologist isn't sure what caused the tachycardia. They are currently doing tests and monitoring my heart. My psychiatrist and cardiologist wanted to see what affects my heart so they put me on a heart monitor for 30 days. I'm on week one and they quickly tapered me off pristiq (4 days of 50MG then none). It has been HELL. I can hardly function. These are my withdrawal symptoms: anxiety, blurred vision, concentration impairment, crying spells, dizziness, fatigue, highly emotional, irritability, lethargy, increased headaches, nausea, over-reacting to situations, repetitive thoughts or songs, stomach cramps, troubling thoughts (suicidal), vivid dreams, and worsened depression. This is only day three being off pristiq, so I have no idea how long these will last but it is terrible. My docs want me to go on pristiq during week 2 of my heart monitor and back off for weeks 3 and 4, but I am going to refuse to start it again because I know I will feel awful during weeks 3 and 4 if I go on and back off that quickly. My husband thinks I should go back on because it helped my depression, but if I ever have to go off in the future (which I don't want to be taking it forever anyway) then I am not sure if I will survive. It will probably push me to suicide. I have heard similar effects of effexor withdrawal. Now I understand why drug addicts go to rehab. I wish there was a place I could go to get help going through pristiq withdrawal. I am constantly dizzy and I can barely function. If you are thinking about taking pristiq, DON'T! Or if you are thinking about stopping, make sure you have F 24 3 months
100 MG 1X day
5/11/2012
 1  Depression Severe headaches, severe muscle pain, weight gain, blurred vision, itchy skin, increased lack of focus (since I already had a problem with that) and I became extremely moody The 1st week I was on this I started getting the chills really bad all day long. Then when I would try to go to sleep I would sweat horribly all night long and have intense stomach pain so bad I wanted to vomit. Also my nose clogged up and got little sores in the openings of my nostrils on both sides. The 2nd week my muscles started to get really really sore to the point walking across the room was exhausting and made my heart pound and then I would be in utter agony because every muscle in my body ached so badly. A couple weeks after that my jaw started locking up and I started getting very intense headaches that no amount of pain killer could help. But I'd started 2 other meds so I had no idea this was the one causing it. So my doctor finally just took me off this one. She tried to wean me off of it by putting me on a low dose of effexor for a week but this withdrawal is no picnic. Dizziness, brain zaps, irrational anger and can't sleep. But my head aches are far less painful and my muscles are getting a little better hope the other problems start to clear up. This definitely needs to come off the market! This has killed my health and my doc said it was brand new when she prescribed it. F 25 5 months
50 mg 1X day
5/10/2012
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 1  depression Loss of tactile sensation, Sweats, tingling in legs, weakness, lack of desire to do anything. I felt nothing. I didn't feel bad, but I didn't feel good. I felt as though I had no soul. This frightened me. M 34 2 days
50 MG 1X day
5/9/2012
 3  Depression So far the only side effect I have had is that I have felt a little dizzy at times and my head will really feel funny, other than that, I seem to have no other side effects. Just waiting to see if this will help me. So many others did not. I have taken over 16 others that did nothing for me or the side effects were too much that I had to get off them. F 48 7 days
50 1X day
5/8/2012
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 1  depression have suffered for ten months with severe diarrhea. 6 to 12 times a day. am homebound due to it. Had to have colonoscopy, endoscopy also 72 hour fecal test and several other fecal tests. developed blood in urine , insomnia, anxiety,Last week had an abdominal ultrasound and also a cat scan in the E.R. four doctors are looking at this now and had me stop taking the Pristiq.. Withdrawals are awful with brain zapping and feelings of anger. I would never take this drug again Have been weaned off it totally 2 weeks now and still have the diarrhea. My gastroenterologist suggested since I have WBC in my stool that a biopsy for microscopic colitis may be the next option. He also said I may need the Mayo Clinic. How the heck can this drug be on the market? I have never had any of these problems before taking Pristiq. F 63 13 months
50 mg 1X day
5/8/2012
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 1  Depression/Anxiety nausea, loss of appetite, insomnia, constipation. On day 1, I could not sleep at all. I was shaking...I felt crazy. My thoughts were very loud, and I could not stop doing things. I crashed the next day. Then the yawning started, and the muscle twitches in my face. Everytime I yawned, my mouth was pulled into a frown or just jerked repeatedly. I did not eat the whole 4 days. I stopped cold turkey and have had no problems, except the anxiety feels a little worse in my chest. F 34 4 days
50 MG 1X day
5/5/2012
 5  menopause - moody Night sweats, constipation, major weight gain. Brain zaps -but with all that still a wonder drug for me! F 47 1 years
50
5/3/2012
 1  anxiety and hot flushes (menopause) side effects-weight gain (carbs and sugar) sweating, strange dreams was taking this for hot flushes, and low and behold this makes you sweat. Also I have high blood pressure and again, this makes your blood pressure go up. I dont think these Doctors know what goes on. F 49 4 months
50mg 1X day
4/26/2012
 3  Anxiety, Mild Depression Hangover-like headache, lethargy, insomnia, lack of motivation, feelings of being outside of my body, lack of any emotion or caring about anything Okay - if you have major depression, this will work to keep you from feeling. The first day I was on it, I immediately felt a burst of energy and being happier. I was excited. All of a sudden, I became very tired. I had a hangover-like headache (which lasted 2 days). I could not sleep and slept 2 hours that day. Normally I rush around trying to get stuff done. I didn't want to do ANYTHING. I sat in bed all day and didn't care what I did, what I had to do - I didn't care about my kids, about my boyfriend, about me... I questioned why I was even alive (although I wasn't suicidal at all... just felt pointless). I pretty much had a complete lack of emotion and motivation - I felt like a complete tired zombie/robot. This scared me - I'd rather be up and down than to feel nothing. I guess if I were majorly depressed, this may be better, but not for me. I stopped immediately because I could barely make it through the day as it was. F 31 1 days
50mg 1X day
4/24/2012
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 4  depression Very tired in the afternoon after work need a sleep neally every day i get home.first 2 weeks bit off food and a bit absent but got better.feel much happier in life only drama is the tiredness not sure if it is the med M 31 6 months
50
4/23/2012
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 1  depression, anxiety vomiting, dizzyness, sleepyness, i felt dopey and could not concintrate, weightloss, blurred vision, headache, the first day i started taking prisiq i instanly felt so sick, i couldnt drive, work or do anything, i felt like spewing all the time, i was dizzy, could not eat and just wanted to sleep all the time. this did not go away and was getting worse with each dose i took, i stopped taking them and now have insane withdrawal symtems i have all of the about but they are now worse, i cant work, drive of pretty much do anything, my husband says that i look like a zombie, i have not eaten a proper full meal since starting these.. how long is this going to last??? i have been off them for a week know and there is no improvement... :( F 22 5 days
50mg 1X day
4/23/2012
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 2  Anxiety, Mood Disorder I feel much worse on Pristiq. I am MUCH less patient, intolerant of loud noises, and i feel angry and on edge all the time. Only one pro to speak of, it is an excellent appetite suppressant, and it helps me focus on my goals. Doing P90X and without it, I would start and never finish it (or anything for that matter) Tried everything under the sun, and i mean EVERYTHING. Zoloft (allergic to) veneflaxine, (Effexor, so- so) Cymbalta (loved, but my body adjusted to Max dose), Celexa (loved but gained 10 lbs) Paxil, (terrible) already on Wellbutrin, (love, but not enough) any advice?? I could really use some... :( F 30 2 weeks
50mg
4/22/2012
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 4  ocd anxiety weight gain (13kilo) heavy sweating, low sex drive. Pristiq worked for me. but weight gain was getting to much no matter what i did. decided to come off it, but that was a nightmare. severe nausea and diarreaha .Tried for 6 weeks. and different tapering methods and none worked. So my Doc put me on lexapro. Stopped Pristiq on a Monday, Tuesday starting taking 10mg Lex for 7 days, then cut that in half to 5mg for 10 days, then cut into quarters for 4 days. Absoluetley no withdrawal symptoms. on day 3 with no meds. and feel great. Now just waiting for the weight to start to go. F 59 2.5 years
50mg 1X day
4/19/2012
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 4  depression my wife says i last too long.....up to 2 hours....or more M 50 6 months
100 1X day
4/7/2012
 2   I suffer from ocd, depression and anxiety. This medication worked quite quickly but was worse for my anxiety! Increased my heart rate 24 hrs a day! Had a major panic attack week 4 into taking it! Felt wired and tense! Had to come off it as It wasn't helping. It did help decrease my worrying thoughts but side effects were toatally not worth it! Prestiq was the 2nd drug i have tried. Citalopram was the first and worked sooo much better so I am now back on that and am much calmer and relaxed about life :) Dissapointed as i was told that it would work better for my anxiety than citalopram but it was way worse! I felt really anxious even after 6 weeks on 50mgs tried going up to 100mg and neally took myself to the emergency department! It increased my blood pressure daily and increased anxiety! I back on citalopram and am feeling much more relaxed and happy! citalopram kicks pretiqs butt for anxiety!!!!!!!!!!!!!!! very dissapointed! F 31 7 weeks
50mg 1X day
4/4/2012
 3  PTSD The drug works great compared to other SSRI's.. Downside is clumps of hair loss at beginning of therapy that tapered off but then hair thinned out over time, now scalp showing through. F 42 1 years
50mg
4/3/2012
 1  depression/anxiety While taking the drug it seemed OK. It definitely was not a cure all and recently I have been switching my approach to more counseling and weaning myself off of all meds. The weaning from Pristiq has been TERRIBLE. I have had extreme dizziness, memory loss, sensitivity to light, extreme irritability and anxiety. I was told by my MD that it caused the low blood pressure and light headedness that caused my to lose conscienceness and wreck my car. I advise extreme caution tapering off of this drug. I have not found many medical professionals who prescribe Pristiq. The Cleveland Clinic advised me that they do not prescribe it. I do not recommend this anti-depressant. I've been on many of them and have never experienced the side effects when stopping any of the others like I have Pristiq. I think it is a very dangerous drug. F 31 6 years
100 1X day
4/3/2012
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 2  Makor depression, anxiety Extreme fatigue, some weight gain, constipation, really bad discontinuation effects, have had to remain on it longer to avoid severe withdrawals F 24 2 years
150
3/19/2012
 1  Severe Depression Insomnia, Hives, Rashes, Skin crawling, MAJOR Hair Loss (I'm a girl... not okay), Blurred vision, Migraines, Paranoia, Manic State PRISTIQ was/is the worst this that has ever happened to me. I have been off this **ing drug for almost a year, and I am still experiencing withdrawl symptoms/ my body is just getting back to normalcy. When I was on Prisitq, I think I had a SEVERE allergic reaction/ every possible side affect to the drug. The fucked up thing is how new this drug is, that my symptoms don't seem to matter and/or measure up to any scientific stats. However, this is what I know.... I have been diagnosed with depression since I was 18. I am now 21, and before Pristiq, I faced a 7 year battle with bulimia, which i overcame. The whole reason I was put on Pristiq was because I was actually doing well and overcame a huge battle with eating disorders, yet still felt the depression. My so called Doctor put me on Prestiq to help my low energy and chronic depression, when in all actuality, my doctor put me on a new anti-depressant so she could make bank, while i was sent back to CA, where I went to school (had to withdraw bc of Pristiq) --- my story is complicated and long, but one fact holds true- PRISTIQ ruined my life. As a young woman of 22, with a 7-8 year history of anorexia/bulimia, I am currently going through Post-Traumatic Stress Disorder from a drug that was suppose to make me BETTER. I cannot in any way compare how awful the few months on Prestiq were to my life long battle with Eating Disorders. The year I spent on/withdrawing from Pristiq was the worst of my entire life and I would not wish F 21 6 months
50 mg 1X day
3/18/2012
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 1  Depression At first it was wonderful! Until about month 3.... I started experiencing decreased sex drive and HORRIBLE increase in appetite. I gained approx. 20 lbs. in only 4 months. Once I decided to stop taking Pristiq I stopped all at once and experienced Horrible Dizziness and diarrhea. The benefits of this medication definetly did not out way the side effects. F 26 1 days
25mg
3/17/2012

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