PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32


RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression None. Great medicine for me. I would recommend it to anyone depressed to try even though it is pricey. F 61 5 years
50mg
2/29/2016
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 1  mild anxiety Partner of person taking pristiq. Compulsive gambling, aggression, lack of caring, lying, unable to feel emotion for anyone but himself. Out of character behavior. No remorse. This drug is really bad for some people. This drug along with a antianxiety drug for 4 years previous to starting pristiq turned my loving husband into a monster. He was addicted and thought he couldn't live without it. Our marriage is ruined and it has affected his health. I did wean him off about a year ago and it was a long hard process. Had to do it myself as his GP laughed at me when I told him about his changed personality. He was becoming a lot more like his old self but I think he is back on them. His old behaviors are back. And his health is going down hill again. To me this drug is poison and I would say be very careful .Withdrawing is like getting a drug addict off of drugs. M 45 4 years
50mg 1X day
2/17/2016
 1  Panic Attacks First, erectile dysfunction & delayed ejaculation; then, numbness in both feet went to ER; it was withdrawal symptoms or what Pristiq calls “Discontinution Symptoms” ). Then, had insomnia that night, as well as, unintended, “multiple orgasms” w/o ejaculation. Felt like brain was being “rewired”. Felt tingling at nerve endings, and had an acute headache in the upper, left, back portion of brain. Contact me if you want MY18 DAY PLAN my M.D. to wean me off of Pristiq ..... FREE! [email protected] DO NOT TAKE FOR PANIC ATTACKS! Especially, if you are any type of Analyst of Everything (or anything); or need your brain to be able to analyze data, facts, etc. M 64 10 days
50 mg 1X day
2/15/2016
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 5  BPD,BP,Major Depressive Disorder loss of appetite, upset stomach/nausea This drug is the best. It has worked better than any other drug for me. I have trie them all. I used to be a frequent flyer to the hospital. This drug has kept me out. Along with it I take Abilify because my depression is pretty bad sometimes. F 52 18 years
100 1X day
1/24/2016
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 3  MDD and ADHD So far, so good. It has only been 2 days and I'm taking it with Trazodone as the add-on which is an additional anti-depressant, pain med and sleep aid. I have a feeling that just these two alone, at the prescribed dosages will be just what I have needed. The lights went completely out for me on Nov. 30 and I've been hiding out ever since, bed all day and night, not bathing, barely cleaning, fits of hard crying and rage. I was put into PHP at a hospital and finally feel like I have a voice in the management of my illness. I was currently taking Lexapro, Wellbutrin, Klonopin, and Vyvanse. I'm hoping that the new meds will eventually ease the depression and sadness as well as keep me focused so I won't have to take so many like before. I will provide an update in about 4-6 weeks. F 46 2 days
50
1/9/2016
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 1  Anxiety/ Body pain Nausea / Severe Headache/ scalp sensitivity The worst! Was in ER because of this Medication, still have headache almost a week off this stuff. Went back to cymbalta M 57 2 weeks
50
12/30/2015
 1  For anxiety Erratic behaviour, emotional, tight chest, ruminating thoughts, tired, This drug should be taken off the market. I have had three years of hell and only just tapering off it this week which has been difficult but I can't wait until it's out of my system. I would caution anyone against taking it and I wish I had never been given it in the first place. Even dropping my dose slowly this week I feel my old self us returning and the tightness in my chest has eased and I'm feeling back in the land of the living F 40 3 years
50/100mg
11/16/2015
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 1  Depression It wasn't until I stopped taking that I realized the two years of inability to catch my breath, feeling like I will pass out, episodes of tachycardia, dizziness, numbness and tingling, yawning, and chest tightness was due to this awful drug. If you want to feel like your cardiovascular and respiratory systems are failing, by all means, take this drug. If you go to a doctor to express concerns about side effects you will be told you are having anxiety. This entire industry is corrupt. F 37 2 years
50mg 1X day
11/8/2015
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 1  Generalised anxiety, panic disorder Ringing ears, 'electric'like on drugs, a burning tingling all through my body, sweating, panic, racing heart,cold shivers.. . I couldn't sleep, just had to concentrate on my breathing all night. I was terrified. I only had one dose! I took it at night as suggested by my doctor. I woke about 3 hours after taking it in a weird, electric atmosphere, my head was buzzing. Then the burning tingling sensation started and lasted on and off for approx 10 hours. This was the most awful night. I felt like I was trapped in a state of panic induced by the drug. Confused, scared. Over 12 hours later I still feel very very anxious, racing heart. I was advised to go to emergency, but I've just been chatting with my nurse sister. A drink is helping me calm down. Now I'll need to miss work to go back to the doctor. This increased my anxiety and panic 10- fold. Horrible. I think it's too strong for me. Or wrong for my condition. I'm hoping it'll be out of my system soon. F 34 1 days
50mg
11/7/2015
Email
 5  Major Depressive Illness - Changes in libido plus ED (these have since gone) - No other side-effects Without doubt PRISTIQ changed my life - and I am grateful for a chance to say so on this forum. Best I do it in point form: - over 30 years of prior major depressive episodes (suicidal thoughts and attempts, multiple hospital admissions, electric shock treatments etc etc) - started on 50mg once-daily, March, 2009 when depressed and suicidal (again) - felt unbelievable signs of decrease in depression and suicidal tendencies after only one week - continued feeling better and better - breakthrough depression at six months - dose increased to 100mg daily - stayed on 100mg for 12 months - asked Doc to reduce me back to 50mg daily as a 'test' because of changes in libido and ED (erectile dysfunction) - have remained on 50mg daily since - NO depression - NO suicidal thoughts - just one happy and grateful person at age 57 (and I fathered a new addition to our family in 2013 - a healthy daughter born in 2014!) - life is so good today - I feel like one of the 'normal' people P.S. as for libido and erection problems - I wanted to 'test' the 50mg dose again and whether libido/ED side-effects would settle down (they did) - BUT - and it's a huge "but" - I was willing to stay on 100mg if need be and live with unpredictable libido and erection issues - my wife and I wanted me to stay ALIVE much more than have an alive penis! M 57 6 years
50mg 1X day
10/27/2015
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 1  Major depression Brain fog:- inability to think clearly, very sore tongue, yawning all the time, eye pain, dry mouth, weight gain (10lb while on this), sleepiness and unable to drive. It seemed to work at first but it was probably the placebo effect. I became very irritable and not myself at all. Small things irritated me immensely - like my partner finishing dinner before me and leaving the dining table - - this was enough to spark a major argument and thoughts about divorce. Totally inappropriate reaction. Coming off it gave me severe headaches and the way it is formulated made it difficult to taper off as well since the slow release effect is created by the pink film coating. Cutting the tablets in half to reduce dosage causes the slow release effect to not work and gives a high spike of the drug. The half life is only 11 hours so after half a day the withdrawal symptoms kick in with force. Glad to be off this. M 60 3 months
50mg
10/21/2015
 5  PTSD/Major Depressive Disorder Side effects were mild compared to Wellbutrin. I feel as though I've got my life back. Remember when reading all these reviews that every "body" is different. I'll take this drug the rest of my life if it continues to work as well as it is doing. F 49 8 months
100 1X day
10/7/2015
 5  depression,suicidal thoughts,mania Pristiq has enabled me to live a stable,functional life. Before Pristiq I experienced highs and lows if rapid mood swings.Overwhelming suicidal thoughts,racing thoughts and unrealistic plans and feelings if invinciblity. Thank God I can now love a peaceful functioning life after 38yrs of feeling out of control. F 39 10 months
100mg
9/21/2015
 1  depressed Headaches, ANGER, agitation, others, addictive , hard to get off Just go cold turkey and deal with the headaches, it only takes a few days. The longer your on it, the worse to get off, but get off before you kill your dr F 50 3 months
9/12/2015
 3  anxiety Felt great until I started itching from head to toe. Have tried many remedies and after eliminating all other causes found out that itching is an uncommon side effect. Now getting off of it will be a nightmare. I experienced discontinuation syndrome after being late on just one dose. Be careful of this drug. If it works without side effects, you are very lucky. F 50 3 months
100
8/5/2015
 4  Chronic depression Only side effects for me were constipation and difficulty sleeping. Changed diet and added Trazadone for sleep I have had chronic depression for years ( 25 at least ). Started on Prozac, went to Lexapro, then others that I can't remember their names. I was put on Pristiq when it first came out. I started with 100MG then down to 50 MG. BEST drug for me. I am now 67 and have weaned myself off the drug completely. Now that was a real challenge! F 67
50 MG 1X day
6/20/2015
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 5  major depression I didn't notice any. I take pristiq in combination with Wellbutrin (300 mg). My dr. had switched me off of Prozac because it had stopped working and a higher dose made me too sleepy. This is the best antidepressant I have tried. I am now able to look forward to living my life every day. I also take other meds for blood pressure, cholesterol, arthritis, and hormones. F 52 8 months
50 1X day
6/16/2015
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 5  depression None Pristiq has helped my depression alot. I was on Prozac for years and then was switched to Wellbutron. I started having uncontollable crying spells where I would cry for hours/days. I had memory loss and times when my mind would just go blank. Pristiq made me feel more normal than I have for years. Unfortunately I lost my job and my insurance. I get the Pristiq when I can, which isnt very often as the price is so high. When I dont have it I'm back to the crying, staying in my bedroom and having suicidle thoughts. I had some Wellbutron left and I take that when I dont have the Pristiq. It doesnt work nearly as well, but at this point its better than nothing. F 54 6 months
50
6/9/2015
 4  Depression, Anxiety Weight loss I have tried many antidepressants over 28 years, and Pristiq is among the most effective for me. No matter what I take, however, I still experience some depression and anxiety; it is likely that no medication will completely eliminate my symptoms. Pristiq does allow me to function relatively normally, and I am grateful for that. I do supplement Pristiq with Seroquel (quetiapine) 25 mg for sleep. Otherwise I would have extreme difficulty falling asleep. I have experienced very low libido over many years, and Pristiq does not seem to have affected this one way or the other. F 72 2 years
100 mg 1X day
6/4/2015
 1  depression pristiq gave me weight gain and headaches. I was on wellbutrin but it lost its help for me was great but was on it for 6 years. and pristiq is not generic. going back to psyc doc and get something else. pristiq is not generic. in between my insulin and other meds the higher price isnt worth it. F 47 2 months
50 mg
5/8/2015
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