PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  anxiety severe iratation, couldnt talk, basically thought I was going to die Please read THIS comment before starting this nightmare of a drug.. I took ONE pill only, thats right ONEEEE.. its been over 6 weeks since that one pill and I still have symptoms!! I still feel at times iritation that is hard to describe.. head feels funny (crazy feeling) I wish I never tried this pill.. I cry probably once a day to relieve stress, This pill caused more depression for me than I had before I took it!!! PLEASE BE CAREFUL TAKING THIS POISON F 51 1 days
50 1X day
9/12/2010
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 1  Depression (Bipolar Disorder) Noticed definite lifting of depression. No mania, no speed-type effect, just an ability to handle negative situations more easily. The problem came in when I tried to stop taking it. SEVERE tinnitis, vertigo, facial numbness (particularly around the mouth), complete loss of libido, all after missing only one dose. The dizziness is so severe that I can't even move my eyes side to side without feeling the location of EVERY nerve in my body! HATE this medication. F 44 6 months
50 mg 1X day
9/10/2010
 5  Anxiety I switched from Effexor to Pristiq because I was experiencing extreme intense headaches - they were almost unbearable! Since the switch, the headaches are gone! I do however experience slight irritability and a slight loss of libido. I experienced these on Effexor too, but they seem better since the switch :) I feel reeeeeally good! I take Pristiq for anxiety - although it has not helped 100% with the symptoms, it has helped me a great deal - it has given me lots of confidence and motivation which I lacked before. I don't have depression, but I have noticed that I am HEAPS happier too! I think it's probably due to the confidence etc boost :) yay! P.S. It's a good feeling to feel like this after trying SEVEN difference types of meds! So a little advice: hang in there! :) M 25 2 months
50 1X day
9/3/2010
 1  anxiety extreme fatigue, dizziness,yawning, lethargy, unmotivated If I knew what I would be going through, or how I would be feeling I would find ANOTHER SOLUTION AND NOT PUT THIS POISON IN MY BODY! I'm mad at my doctor (although she put me on this med to help)for suggesting this med, after I told her I didn't want to go on ad's. I tried to stop on my own and ended up with bad anxiety attacks. F 44 5 months
50mg 1X day
8/22/2010
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 5  depression Headaches when I'm withdrawing and when I take the pill at night I have difficulty waking up in the morning especially if I don't have to go to work. If I don't set my alarm I can easily sleep to noon. Pristiq is my miracle drug, I just wish it wasn't so much money. Insurance doesn't cover much and there is no generic at this time. F 21 2 years
50MG 1X day
8/20/2010
 3  DEPRESSION,ANXIETY at first i didnt want to eat at all now im noticing an appetite increase but nothing like when I was on Lexapro could just be in my head though , SOOOOOOO SLEEPY I CANT STAND IT I'm always running late for work Works pretty good, not as good as lexapro though but my head is clearer on this one lexapro makes me feel like a zombie,its August so I think i'll stick with it till the end of the year to see how it goes F 25 2 months
50 1X day
8/17/2010
 3  depersonalization and depression Even MORE weight gain than with Effexor. Absolutely zero interest in sex and greatly reduced sexual functioning. Very hard to get good quality (deep) sleep. I tried this after Effexor stopped being effective (pun intended)and it wasn't really a whole bunch better. M 42 6 months
50 1X day
8/6/2010
 4  depression At the beginning (first couple of months)- night sweats, vivid dreams After having been on it for awhile: extreme hot flashes during the day with excessive sweating, vivid dreams, inability to lose weight, no sex drive, trouble recalling words I have been taking 50 mg of Pristiq for a year with 40 mg of Celexa for depression and 3mg of Lunesta (when needed) for sleep issues. This has been the best combination for me, but it took some time to find the right dosages. My psychiatrist told me that it would take about 6-8 weeks to feel the full benefit of Pristiq, and I am glad that I stuck with it. After one year of the proper dosages/combination my doctor said that it's ok for me to taper off of the medicines because I am doing so much better. F 28 1 years
50 mg 1X day
8/2/2010
 1  Depression Insomnia THEN oversleeping, inability to concentrate, lethargy, weight gain I HATE THIS MEDICATION. It doesn't work. It is a blatant ploy by Wyeth to make money and it's a f'ing joke. I have never had such an issue oversleeping--I've always had insomnia but now I am drowsy all the time and can't get out of bed in the morning. I was on Effexor (which worked) and then my psychiatrist switched me to Pristiq because it was being marketed as the "side effect free Effexor." I can't get off it because the withdrawal is terrible. This kind of experience absolutely causes me to lose faith in psychiatry. Given the number of times I feel like killing myself, I am starting to believe in the sang "psychiatry kills." So unhappy with this stuff. F 23 2 years
25 1X day
8/2/2010
 1  anxiety While on med: extreme fatique, headache, inability to concentrate While tapering off med - now over one week: have never felt so bad - severe headache, severe constipation, severe nasuea, severe malaise, severe irritability - and this is being bufferred somewhat by tapering back to prozac, which nver caused me any of these symptoms - think twice before even thinkin gof taking this hellish med M 44 3 months
50 MG 1X day
8/2/2010
 1  Clinical Depression, anxiety diarrhea, increased anxiety, still depressed, but not suicidal, I also tend to be more impatient with outbursts here and there (which isn't normal for me) My doc told me that this medicine wont be more effective in the higher dose of 100 mg (and he chuckled to himself as he said this) it will only increase the side effects... This is one of the worst meds I have been on since taking paxil for 6 years of my life. The withdrawls from this medication is horrible and unbearable...I intend on getting off this med to something more effective at my next doctor's appoitment. I would suggest to anyone given this med or any medication, do your own research on the medication both postive and negative before you decide to let it mess with your brain. My doc is an idiot and also told me that all antidepressants were the same. I can't see how any medication having such severe withdrawl symptoms (discontinuation symptoms) can be good for someone's body or state of mind. I have 3 little children who are all under the age of 6 years old who are dependant on me there mother to be coherent, and capable of being mentally and emotionally there...and with this drug since I have taken it...I can now see how it has messed up my life, taken me away from things I love, and enjoy. I seriously regret this medication...look into withdrawl symptoms before you decide to start taking a medication such as this. So that you are aware of what could happen if this medication doesn't help you and you need to get off. Furthermore, regular MD doctors who haven't specialized in these types of medicines should never be allowed to prescribe them...it should be left to a phychiatrist or a type of psychologist who is able to prescribe medication. Not all antideppresants will effect you the same...my doctors are morons!!! F 29 5 months
50mg 1X day
8/2/2010
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 3  Depression Hair loss, constipation, insomnia if taken at night, grogginess if taken in the morning, painful feet and hands (as if being beaten by wooden paddle), aching joints, night sweats, hot flashes, memory issues... It did improve my depression which is why I have remained on it so long. Went through unbelievable withdrawals when trying to get off it; so bad that I started taking it again in just a few days without it. Am going to revisit getting off it with doctor. Perhaps someone knows of work-around to the wretched withdrawals of this medication. Would recommend if no other medication has worked and depression is SEVERE. F 43 1.5 years
50MG 1X day
7/28/2010
 3  to replace prozac for OCD Currently listed this med as "somewhat satisfied" - but has potential to easily go either way. I was on 40 mg of Prozac and 1 mg of klonopin for OCD / anxiety / depression / slight ADD. The Prozac tended to cause some cognitive clouding. Doc suggested 50 mg Pristiq and am trying that with the 1 mg of klonopin. The OCD / anxiety / depression / slight ADD all seem to be taken care of. The thing that is curious about this med is now it seems like the 1 mg of klonopin makes me over-sedated and my bad habits of drinking coffee and smoking - which seemed to have helped "stimulate and focus" in the past now seem as though they are not needed - will get over sedation feeling in the morning, head-aches, and some over stimulated agitation throughout the day when using these in pre-Pristiq quintiles (pack of smokes a day and drank coffee on regular basis throughout day). Under doc's supervision have started to taper off the klonopin in .25 mg increments and have reduced M 44 3 months
50 1X day
7/25/2010
 1  Anxiety, depression 40 pound weight gain. Slow, but sure disconnection from the world. Completely medium about everything. Tried to cold turkey off and it was absolutely horrible! Going back to the doc to get off this med - really don't like it. F 50 2 years
50 mg 1X day
7/25/2010
 4  Panic Disorder, Anxiety Disorder Makes me a little sleepy Was on Lexapro for a week with major anxiety and panic. Stopped it cold turkey and went to Klonopin .5x 2 a day. The Klonopin helped my anxiety and stopped my panic attacks. Then my pdoc decided to try Pristiq. I have been on it for 2 weeks gradually building up my dose to 50. I have been cutting the 50's in half and quarters to get use to the medicine. I am now on 50mg per day and it is helping me with my anxiety and panic attacks. I have backed off the Klonopin to one .5mg per day. I actually can tell when it is time for my Pristiq as I start getting a little shaky. After I take the Pristiq, I usually feel very good in about an hour or so. I wake up happy and the bad thoughts are starting to disappear from my mind. Pretty good stuff. M 36 2 weeks
50 1X day
7/24/2010
 4  depression and anxiety Breakouts of sweat I was on 50 mg for nearly a year and recently my new doctor increased it to 100 mg because I wasn't feeling any better. I am also taking 300 mg of Wellbutrin once per day. I have felt much better after the increase. I can deal with the sweats. F 34 2 months
100 mg 1X day
7/21/2010
 1  GAD, panic attacks Racing thoughts, nightmares, waking up at 4 a.m., dilated pupils, tremors, lack of appetite. This drug overstimulated me to the point where I thought I was going crazy. It took away some anxiety about certain life situations, but it added a manic feeling. I can see it working for people with deep depression because I definately felt like I was on a stimulant. Take comments on here with a grain of salt though, everybody has different chemistry. F 30 5 days
25 mg 1X day
7/18/2010
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 3  Depression My side effects consisted of involuntary muscle movement, apathy, low concentration, intense dreaming (usually good), blurry vision, gastric upset, and electric shock sensations going down my arms when I cough or sneeze. Pristiq seemed to help me in the first month. After that month it seemed to start having an opposite affect on me. I became more annoyed and seemed to have more anxiety than before. I will say it did help in the beginning but once my body got used to it,it only proved to be a nuisance. My doctor diagnosed me with situational depression. It has been a few rough years. Now I feel much better and have taken myself off the medicine completely. Luckily I had no withdrawals when coming of it, other than sleep issues and I gained a few pounds. I weaned myself off by taking it every other day. My blurry vision has yet to get better. I am worried about this. F 42 6 months
50 mg 1X day
7/16/2010
 5  Depression/Inattentive ADD Absolutely None For the past 5 years I have tried many different AD's. Effexor, Lexapro, Wellbutrin, but was on Prozac and Adderrall for about 2 years and they stopped working gradually. I have been taking pristiq for 10 days and within the 1st day it made an amazing difference to my outlook, no more crying for nothing, feeling happier than I have for about 6 months. Might not be for everyone, but as long as this doesn't just stop working, I will be happy to take it for as long as I need it. F 49 10 days
50 1X day
7/12/2010
 3  Depression Weight Gain (10kg in 12 months) despite attending the gym 5 days a week, brain zaps and sinking feeling in less than 24 hours between doses. These withdrawal symptoms became intolerable if dosage missed in 24 hours. Tiredness within 30 mins of dose, brain fogginess, short term memory loss and loss of concentration. Attempted moving to 100mg tablets during several periods which resulted in increased stress, agitation, frustration and heightened aggression. Was very good within the first few days of helping me get work done and focusing, but these benefits faded after the first month. It was successful in relieving the depression, however, the side effects of withdrawals/discontinuation during a 24 hour cycle are very unpleasant. The weight gain is another cause for concern and certainly doesn't help with maintaining a good psychological state. I used to take Pristiq in the morning, but found that within 30 mins or so of dosage that I would feel tired enough to sleep. So, I changed to a PM dose which had the side effect of helping me sleep and made my performance during the day better. I would love to come off this medication but considering I have withdrawals even during my daily dosage cycle, I am really hesitant to go down this path without having time off work and some other therapy/medication to relieve the symptoms. I would recommend anyone considering this medication to avoid unless all other medications had failed - and I wish I had never started them in the first instance. M 31 1 years
50mg 1X day
7/10/2010
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