PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32


RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  depression/anxiety more depression this drug just didnt work for me and made me worse. it did nothing for anxiety either and is very hard to get off of. M 19 2 weeks
? 1X day
11/29/2011
Email
 5  GAD, major depressive disorder Trouble sleeping if taken in afternoon, excessive yawning, restless legs After coming off of Effexor, the withdrawl symptoms are a breeze if you miss a dose of Pristiq. I spent 3 months of my life being unable to function coming off of Effexor 75mg. The only side effect of missing Pristiq, aside from being very emotional (for me) is the wanting to stay in bed all day and maybe a slight headache. No nausea or vomiting here, like with Effexor. For me, the benefits greatly outweigh the negatives, and helps me function every day without having a panic attack over things like going to work and thinking the world can end while I'm there. The restless legs seem to be the worst side effect personally, you can usually get around it by taking it as early as possible. F 27 8 months
50 mg 1X day
11/18/2011
Email
 1   There is NO reduced serotonin or chemical imbalance. The idea of the psychiatry is to reduce unwanted behaviours (mental illnesses such as depression, schizophrenia) by 1) torture, 2 death. Everything else is a lie. In psychiatry mind is "sick", similarly to joke is sick. Psychiatry typically reduces symptoms by causing brain damage. Paranoia is quite common in mental health patients, people are "helping" you. For sources of depression you have to find REAL physical or NEUROLOGICAL problems and treat them. M 30 1 days
50 1X day
11/16/2011
 3  anxiety/depression I have gain an excessive amount of weight. I am not as depressed as I was before taking pristiq, but now I am starting to get depressed about the weight gain, because I cannot fit any of my clothes. I used to weigh 135 lbs, now I weigh 185 lbs. F 41 12 months
1X day
11/14/2011
 4  Depression, Anxiety Lots to begin with, but the only ones lasting were short-term memory loss, constant bruising all over my legs, clumsiness, worsening vision, craving for carbs and weight gain (8 lbs in 8 months). This medication brought me out of utter despair. I was at the brink of suicide and now I'm functioning again. The side-effects are similar to what I've had on SSRIs, but I'm willing to put up with them for the positive effects. Fat and happy is better than skinny and miserable. I'd have given it 5/5 if it wasn't for the weight F 25 8 months
50 MG 1X day
11/11/2011
 1  Depression/Anxiety I have tried many different antidepressants and this was the WORST! I felt like a different person. My personality pulled a 180 and a crazy person was born. I was SO paranoid I had to lock myself in my bathroom when I was home alone. I have always got straight A's and have never been in trouble. After being on this drug I completely blacked out and started doing things completely against my morals. I was arrested and had to pay over $1000 and I am in the system. The doctor took me off of it and ever since I have been my old self. F 20 6 months
100mg 1X day
11/3/2011
 1   Extreme anxiety, shaking, depressed, loss of appetite, dillusions, completely irrational thought patterns ALL I CAN SAY IS PLEASE DON'T TAKE THIS POISON. If you want to cross over to the dark side, this is the med for you. I only took 2 doses and I was effected for a full week and I honestly thought I was in hell!! I became extremely irrational and withdrawn from my family and everyone around me and it gave me far more depression being on it than before I took it!! Also brought back suppressed memories, awful awful drug. F 35 2 days
50mg 1X day
10/30/2011
 1  depression Severe headaches, anxiety, severe nausea, unable to see, muscle spasms, chills, odd body pain, gastointertinal pain, bloating, racing heart, disorientation, aggravated dyslexia (severe), eye pain and pressure, pressure in neck arteries, brain *zaps* and odd sounds in ears, extreme thirst, sleeplessness ***DO NOT TAKE PRISTIQ!!!*** I had one dose in july; atypical migraines. Could not get ahold of my Dr, took Maxalt w/ the drug and thought I would have a stroke, along with the other symptoms. It is now the end of October and I have been sick with almost every *rare* side effect listed, currently a lung infection. My health went downhill the day I took this med; DO NOT TAKE IT!!!! Do not let a family doctor Rx it---find a good Psych Neuro. My Neuro said the drug is so new, they have NO IDEA what problems it causes. This drug will kill people--plus it was never developed for this use; look up Ellefore, which originally was sold as a non hormonal replacement for menopausal woman. The UK did not approve the drug. Wyeth should have to live through the hell I have been through, and I ask---when does this quit??? F 51 1 days
50mg 1X day
10/30/2011
 1  Anxiety/panic attacks Inreased heart rate, constant anxiety, increased panic attacks I HATE this med (I mean POISON!!). I have only been on it for 30 days and I feel like I am going crazy!! My anxiety and fear are worse than they have EVER been. I used to only need to take a small dose of Xanax 0.25mg). as needed, but since starting on Pristiq, I am taking a total of 1.0 mg or more a day, just to deal with this increase in panic and anxiety! I have weird, vivid dreams and wake up several times during the night with a racing heart which then of course spirals into a panic attack!! I am weaning myself off this crap starting today! STAY AWAY FROM THIS MED!!!!!!!!! F 40 30 days
50 mg 1X day
10/17/2011
Email
 1  depression Loss of concentration and focus, fuzzy headed, loss of hair, insomnia, weight gain, headaches, fatigue, irritability, no sex drive, shaky, zombie like emotions, no desire to be around other people, HORRIBLE - HORRIBLE DRUG. It seemed to work okay at first then after several months it went down hill fast. The very worst part of this drug is coming off of it. THE WITHDRAWALS ARE EVEN WORSE. I was not taking any other meds and was only on 50 mg a day, but when my doctor and I decided to wean me off of them -- I was close to suicide for the first week. PLEASE do not consider this drug. I will never take another antidepressant ever again because of my experience with this vicious drug. I would rather deal day to day the best I can than go through this. I am on my 8th day and a bit better, but still having a very hard time with puking, diarrhea, headaches, vertigo, blurred vision, no energy, my hair is falling out even more now! PLEASE PLEASE PLEASE avoid this medication -- take something else!!! F 49 2 years
50 mg 1X day
9/29/2011
Email
 1  Mild Depression/Mild Anxiety memory loss, loss of motivation, increased thoughts of suicide, increased depression, disoriented, forgetful, sleeplessness Overall I really feel this med set me back years in my stuff I was working on. Now that I have been off of it (and any other med) I am feeling like a recovering alcoholic with the work I have to do. F 37 1 years
50mg 1X day
9/27/2011
Email
 2  for anxiety/mild depression extreme anxiety and agitation especially in the morning. 1st week fear of being alone, headache and nausea too for 1st week. I'm not sure if I will continue this drug, if the anxiety and fear doesn't subside. It's been a roller coaster ride from day one. the daytime seems ok for a few hours but outside that anxiety pulses through my veins. Ativan is the only way I can go to work. For people whom had severe anxiety before, be prepared to feel even worse. It's scary. I will try for 4 more days and that's it. Doctor says 3 weeks is needed for pill to be effective. Good luck everyone. F 42 18 days
50 mg 1X day
9/17/2011
 1  Depression/Anxiety Dilated pupils, heart racing, jittery, diconnected, loss of sleep and feel tired at the same time (tired and wired) loss of orgasm, loss of appetite, confused and foggy, blurry vision at times On this drug for 2 days and felt wierd. Dilated pupils were very annoying and I didn't sleep after the first pill so today I am so tired. Feel foggy, disconnected and I'm sure this is partly from no sleep. Just called the Dr's office they said disc. b/c of the many side effects already. I wonder if I stayed on it a few months how I'd feel but to scared to find out esp after all the other bad reviews! F 35 2 days
50 1X day
9/13/2011
Email
 1  Major Depressive Disorder and GAD Weight gain and an inability to lose weight, despite frequent exercise. I crave food constantly, always feel hungry, especially for sweets and carbs. My anxiety is worse, I constantly fidget and cannot keep still. I feel numb on this med and drained of creativity. I cannot cry over things which matter but tiny things will make me bawl my eyes out, like a television commercial! I really wouldn't recommend this medication to anyone, it's been a horrible six months :( F 26 6 months
50mg 1X day
9/5/2011
Email
 5  Depression & CFS slight stomach distress (infrequent) I have been on Pristiq now for over a month, and I am quite happy with the results. I take 50mg in the AM, and I feel enough energy to get through the whole day at work. Although I still feel tired at 6:00 in the morning, the debilitating fatigue is gone. I am slowly losing weight, and I started feeling like my happy self again. So far, I haven't experienced any other adverse effects besides an upset stomach once in a while (not daily). I like this medication, and I hope it won't "poop out" on me for quite a while. I really could get used to this good life... F 41 5 weeks
50mg 1X day
9/1/2011
 2  Depression Four days after I started taking Pristiq, the skin on my fingertips began to peel off. I told my therapist, saw a dermatologist and an urgent care specialist, and they all told me the Pristiq could have nothing to do with it. It continued to worsen, and the solution my dermatologist assured me would work didn't even slow it down. I lost three layers of skin from all my fingers - it bubbled and peeled down to my palms. I stopped the Pristiq and the peeling and skin condition in general has vastly improved. I know this reaction is probably VERY rare, but I'm just putting it out there in case it happens to someone else and their doctor tells them the same thing mine did. Unfortunately, the medication DID seem to help me emotionally, but the finger peeling was definitely a reason to switch. Withdrawal was unpleasant. I think this medication would definitely help some people, and I wish it worked for me. Don't be afraid to try it, but don't hesitate to go off it if your body reacts weirdly like mine did. F 19 14 days
50mg 1X day
8/15/2011
 3  Depression & anxiety panic, low self thoughts, just getting through day, questioning if I really want to be around, general feeling depressed and quick tempered and argumentive towards anyone in my path, withdrawn from family members Pristiq is better than effexor xr 250mg at first but I've slipped into just cannot be bothered anymore when I should be happy and positive. I've lost my constant planned thoughts of how to commit suicide like on effexor but now it is replaced recently over last two months that I do not see myself alive forward to today. I dont care if I live or die anymore M 49 7 months
100mg 1X day
8/12/2011
 4  depression, chronic fatigue slight nausea and dizziness subsided after a few days, none so far This is my 7th day on Pristiq (4th on 50mg). I have noticed an increase in energy; more focus and a renewed interest in having conversations with friends and coworkers. I am still tired but the debilitating fatigue that used to consume me is gone. I feel overall happier and less tense and worried. I was able to cut the dosage for both Adderall and Xanax in half. Have energy for most of the day but am quite tired at night. No sleep problems or weight gain so far. Pretty happy and hopeful about this med. Will keep you posted. F 41 7 days
50mg 1X day
8/2/2011
 2  Major Depression Horrible mood swings, anger, hostility, sadness, crying for no reason, headaches. This medicine turned me into a crazy person! It was like having the worst PMS x 10. My moods changed on a daily basis. I began having anger outbursts out of the blue, throwing things, slamming doors and yelling at anyone who got in my way. I cried hysterically for no reason. I began to hate the job I actually normally love. Everything irritated me. I have now stopped taking the drug and went back on Celexa. I am really hoping I get better because this is no way to live. F 34 45 days
50 1X day
8/2/2011
Email
 3  Depression By the fourth day, I experienced profuse sweating and periods of extreme anxiety that would last for 4-6 hours per day. I never suffered from anxiety or panic attacks prior to taking this med. I gave up after ten days when I got tired of not being able to get anything done at work due to the irrational anxiety. This drug worked great for depression if it wasn't for the prolonged anxiety. I felt great, had tons of energy, and it did not make me drowsy or yawn. Maybe if I had been able to stand taking it long enough the anxiety would have passed, but the duration of the anxiety made it too difficult to continue to take the medicine. F 34 10 days
50 mg 1X day
8/1/2011

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