PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Anxiety and depression While taking Pristiq, I developed restless leg syndrome, indigestion (constant), nightmares on a regular basis, nausea, night sweats, insomnia, and constant cravings for sugar. I have taken Pristiq for a little over a year. At first it did make me feel better and i did survive the situations that were causing me immense grief and stress at the time. So yeah, it helped. But I have to say that during the time I took it, I also developed major problems with my bowels including IBS and diverticulitis. Maybe it's a coincidence, but since going off my meds, both have improved drastically. Going off has been a nightmare. I am at one full week off and still experiencing dizziness, restless leg syndrome (and no I didn't have it before and don't take anything else to cause this), nausea, cravings for sugar. I have heart palpitations both with and without it now(yes, I've been checked and nothing shows up). I'm having severe cramping in my fingers and toes. And my arthritis seems to have doubled in intensity since I have begun to ween myself off of it. I have experienced a major weight gain although I have been trying to diet and exercise regularly so I fully believe the no weight gain is a lie. I can't say that I wouldn't take it again if recommended but I would have to seriously consider it as it doesn't seem that the side effects are worth it, or are the withdrawal side effects worth it. F 53 1 years
50mg 1X day
7/31/2011
 3  Depression, chronic fatigue jittery, slight nausea, mild anxiety This is my 3rd day on Pristiq and I am still taking 25mg (breaking the 50mg in half). I am tapering off Prozac which has eased my depression but still left me fatigued all the time and with zero libido. I take Pristiq in the AM and I can feel a slight burst of energy already. Despite the mixed reviews I have high hopes for this med as I used to take Cymbalta which was amazing for 2 years...then the inevitable "poop-out" came. Withdrawal was god-awful but I'd rather LIVE my life in 2 year increments instead of just dragging through it. Will keep you posted on how the next days are going as I go up to 50mg tomorrow. Wish me luck... F 41 3 days
25 1X day
7/29/2011
 1  Depression/anxiety Complete loss of sex drive, intense dreams, SEVERE sweating i will NEVER let any one I know take this poison. The side effects far exceed the "benefits". And if you miss a dose, you literally go insane. Complete withdrawal from this drug is the hardest thing I've ever had to do. Realizing what this drug has done to me, I will never take it again, even though I am dying with out it right now. I feel like I'm constantly being electrocuted. I strongly feel the FDA will pull this poison off the market soon (not soon enough) and there will be many law suits. But nothing will make up for the life lost for all the people that are suffering, and have suffered, from this drug. F 24 4 months
100mg 1X day
7/28/2011
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 5  ADD Depression/Anxiety Jittery, increased sex drive, appetite loss I was on pexeva for anxiety/depression. it did help me a lot but i had a very hard time having an orgasm on it and it just made me chill out about htings in general. after i went through a rough period in my life wit losing my job, moving and breaking up with the one i love (were back together :)) i got depressed and suicidal. i went to my psych and i told him Ive've always had ADD but I dotn like stimulants. and ADD makes everything worse. so i told him i wanted meds for it and soething else for my depression going through...so he told me aout Pristiq! and he said it works for ADD and depression and anxiety. ok so let me get to the point..i stopped pexeva cold turkey for a day i got migraines and crazy dreams and felt like i was f*d up. the next day i started Pristiq...let me tell you that the 2nd day i took the pill i felt like a new person! it gave me a jittery feeling at first kind of like a stimulant but it made me wanna get up and get a grip on my life and find a job. i had anxiety at first but i still felt GOOD. im on day 8 and i feel AMAZING. ive never felt so good and SO FOCUSED in my life. this med is great for ADD and for depression. i wouldnt recommend it as much for anxiety but if youre happy and you learn to see anxiety as a normal reaction to things in life and you accept it it eventually gets less and goes away. I do a lot of exposure to situations and i do get anxious inside but this medication gives me the confidence to go through tough situations and ex F 26 8 days
50 1X day
7/27/2011
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 1  PRE TENSION SYNDROME Foggy headed, out of control Never taking this again!! I am going back to birth control and ADD meds I am not depressed and told the doctor I just have ups and downs 2 weeks before my period! F 27 1 days
50 1X day
7/26/2011
 1  Anxiety/Panic Disorder 2 doses = Suicidal thoughts. My "doctor" gave it to me for panic disorder. By the second day, I had witnessed worse panic than anything my disorder was able to do to me. Absolutely horrific. Thank god I stopped after two days, and it still took me 4-5 days to shake the after-effects of that poison. Everyone is different. Maybe this will help some people, but it was a nightmare for me. M 42 2 days
50 MG 1X day
7/21/2011
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 5  severe depression night sweats the first few weeks This drug saved my life. I was going down a dark road. A single mother, way too much stress for one person to deal with. Started Pristiq in 2009, started feeling better within 2-3 weeks. Was able to come off in June 2011 with zero side effects. I have been doing wonderfully. Not sure where I would have ended up had I not been put on Pristiq. F 32 1 years
50 MG 1X day
7/19/2011
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 1  depression Extreme craving of sweets and carbs. I had been on a low carb alkiline diet and was fine and losing weight with no cravings for the sweets and carbs. As soon as I went on pristiq, there was no end to the horrible hunger pangs and I could not get eat enough sweets and carbs to satisfy the hole in my stomach. I felt foggy and confused at times over making even the smallest decisions. I had trouble sleeping through the night. I felt nervous and agitated. After 7 days on this drug I am going off of it before the horrible withdrawal symptoms kick in that I'm reading about. Hopefully I am stopping it before that happens. I do not recommend this drug. My doctor assured me it would not cause weight gain, but the hunger pangs that started within one day were unbearable and the only change to my life was pristiq. Do not believe the spiel about no weight gain and no affect on libido. It isn't true. You are the guinea pigs for this new "miracle" drug and it will come out later, that, yes in fact it does cause weight gain and affects sex drive. Don't take this drug. F 57 7 days
50mg 1X day
7/15/2011
 2  depression irritable, short tempered and cry if I miss a pill (by only a few hours) Pristiq works well at first. Originally on 50mg, after a year it stopped working so doc upped dose to 100mg. Worked well again for another year now is not working so well again. I would love to stop taking pristiq but am so scared to stop because of the horrible side affects I get when I miss a pill by say 8 hrs. The first symptom in light headed, dizzy feeling. Heart palpitations. Then the crazy mood swing. My family notice immediately when I have missed a pill. My mum has gone even so far as to monitor that I take one every morning same time so I dont have a mental break down. I will go to my doc to cease taking this. Not recommended. F 35 2 years
100mg 1X day
7/14/2011
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 4  depression slight nausea F 49 1 years
200 MG 1X day
7/13/2011
 4  Depression, Anxiety, Suicidal Headache the first couple of days I switched to pristiq from 75 MG effexor because I thought there might be a positive change in side effects. Effexor made me really sleepy and I always had a foggy head. It also killed my sex drive. Now with pristiq, all of these symptoms have lifted. I feel better than I have in years. The only problem is it doesn't seem to help the bruising problem. I look like a beaten woman. F 24 7 days
50 MG 1X day
7/10/2011
 3  Depression Pristiq worked well for me for 6 months on the 50 mgs than it stopped working switched to the 100mg and know its working again. Works really well for depression and anxiety makes you feel really confident, talkative, makes it impossible to orgasm and it does keep you up at night.Hopefully it won't poop out on me. WHen switching doses you have to give it at least 3 weeks to feel the effecs. Initial side-effects do subside M 20 7 months
100mg 1X day
7/5/2011
 1  Depression, anxiety Severe depression, akathisia I've tried many drugs, and this is absolutely the worst I've ever taken. M 35 1 months
30 mg 1X day
7/4/2011
 5  Major Depressive Disorder None It's worked best for me out of the many that I have tried, with fewest side effects. F 48
150mg 1X day
6/29/2011
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 1  Anxiety Disorder, Depression Intolerable anxiety, three months cringing in bed,18 months later and eight medications to bring it down to "tolerable". I included some "essential" reading in my comments. Best of luck ... ... After I went off Effexor (375mg) my depression returned, and my "high reputation MD" insisted on 100mg of Pristiq (aka "Effexor or steroids"). After I was in "severe anxiety", he raised it to 275mg ... ... and I wound up "cringing" in bed for three months, while he kept insisting the two were identical (I'm convinced there was a kickback). After some research, I switched MD's, went on Effexor, and we finally found the “eight” medications that “reduced” the side effects to “tolerable”. It’s now 18 months later, and I still feel like I'm plugged into an electric socket. If considering, or on, Pristiq, essential reading, "Top 5 Reasons to Forget about Pristiq" by Dr. Carlat, a prof atTufts Med School, (www.carlatpsychiatry.blogspot.com/2008/03/top-5-reasons-to-forget-about-pristiq.html) … ... the lawsuit at www.i.bnet.com/blogs/pristiq-complaint.pdf for (great info on Wyeth's future without Pristiq) … ... and google “lawsuit pristiq”. BTW When I asked the orig MD why he insisted on Pristiq, “because it has fewer side effects”. The SOB was white and shaking after I said “you %^&, I didn't have any side effects with Effexor. If it were me, I’d insist on Effexor (and don’t give Wyeth your money, get the generic). M 57 3 months
275 1X day
6/14/2011
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 4  bipolar depression anxiety i switched from lexapro b/c the sexual side effects were unbearable. no sex side effects w/ pristiq, although i'm curious as to whether i need this or not. M 23
50 1X day
5/29/2011
 1  Anxiety Insomnia, uncontrollable shakes, jaw clenching, dialated pupils, manic, fast beating heart. After one dose of this deplorable medicine, I decided to desist right away. Never before have I been in such a weird head space. I'd rather be miserable than take this stuff EVER again. M 19 1 days
50 MG 1X day
5/5/2011
 1  Anxiety/Depressive tendencies Loss of sex drive, Anxiety, Panic attacks, Suicidal thoughts, Depression, Aggression, Aggitation, High BP, Nightmares Taking this drug has been a distressing experience. The side effects have outweighed any possible benefits of taking Pristiq. I would not recommend this to anyone. I missed a dose and found myself in the ED with the worst panic attack of my life, I felt like I was going to die. I have sinced weened off this drug and it has been a nightmare to say the least. Dizziness, anxiety, body aches + cramps, lethargy, aggitation..just to name a few. If you choose to take any AD be sure your Dr discusses withdrawals with you - they are hell F 23 6 months
150 mg 1X day
5/4/2011
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 2  depression started out with mouth ulcers, skin blisters, rosacia (esp around eyes), stiffness in neck and ankles; by month 3, full body muscle pain rated at 8 or above. Doctor kept telling me that what I was experiencing couldnt be Pritiq but Pristiq is all I'm taking and never had these problems before F 47 3 months
50 1X day
4/26/2011
 4  Depression & Anxiety. Improvement on Effexor XR 150mg. Suicidal thought diminished. But I feel Pristiq is holding me up to get through day. Cannot sleep until midnight, wake up at 5a.m. on the dot but feel drowsy early afternoon and have need to lay down about 4p.m. regular basis and wake up 6.30p.m.. Focus while driving is a concern. There are days I'm on a race track, and days where I can only focus in front of me and feel dizzy focusing on vehicles either side of me. If I focus on something too long like computer or reading I become tired. I know if I have missed a dose within 3 hours. Withdrawal kicks in. Most of side affect that Effexor presented like calmly plan my dimise in suicide are gone. Still wrestling with not being able to face employment and feeling like everyone is looking down on me. On Pristiq I can get through the day with routine items which has improved my social life within home but I still have to get past my GP whom thinks getting a job is the cure. I'm wrestling with that one. Previously a supervisor in production output, I am rating myself pretty low as a worker. Nobody out there to get over this hurdle, so it is play breach game with Centrelink on Newstart allowance. Cant be signed off as a nut. I don't hear voices. So when I do go off it's 4 hours with police lock up, 6 hours A&E, ambulance, 24 hours mental health lock up then back on streets again. M 49 2 months
100 1X day
4/25/2011

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