PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  fatigue from LUPUS Mild anxiety when active, or after 12 hr shift/200mg Headache, palpatations. Has given me my life back. Now able to do what I love as ER RN, be active with my son and husband when needed. Can go days without taking it - when I do take it I feel positive, not quite euphoric, but just happy and alive. Have had depression for years and this is the best drug I have ever taken without risk of addiction or side effects. I love it. F 50 12 months
11/14/2006
 5  lifelong daytime drowsiness For the first few months on Provigil I experienced flu-like symptoms - aches and chills - doctor said it was common, and gradually they went away. If I take too much, I can get a little shaky, but not anxious. Like others, my urine seems darker and stronger-smelling. The most annoying side effect is that I clench my jaws to the point of headaches sometimes, AND - this is the worst - I compulsively push my tongue against the back of my lower teeth so that after awhile my tongue and gums are sore; I've even gotten irritation sores on my tongue. Even though I'm aware of it, I can't stop it. My dentist doesn't think I'm hurting my teeth, anyway. And it's bearable. Before Provigil, driving any long distance was agony because I had to fight drowsiness so often. (A sleep test said I have "fragmented sleep" but found no cause.)Now I'm totally alert, and the drug is amazing in that I can stay alert and interested through boring lectures and meetings; I contribute and perform much better. (I wish I had had it in college!) I read somewhere that it can make antidepressants more effective (I take Paxil and trazodone) and I really believe it: sometimes if I'm feeling down, I take Provigil for that purpose, it really helps. Interestingly, the drug seems to create a tolerance very quickly - if I take it for several days in a row, I have to increase the dose quite a bit; if I'm trying to work late in the evening, it seems that even taking more Provigil after dinner doesn't really keep me up much later. So I try not to use it every day, and that brings back its potency quickly. I take anywhere from zero to 100 mg to 200 mg and very occasionally mor M 61 4 times
11/14/2006
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 5   sorry, I meant to say 4 YEARS - this drop down menu is easy to screw up. M 4 years
11/14/2006
 4  Narcolepsy Mild-Dramatic Mood Changes, Depression, Loss of Appetite. If I personally take it after 8-9 AM, I will be awake well past midnight-1 AM. *** If anyone wants to email me about Provigil and or Narcolepsy, I have a lot of unanswered questions. It would be nice to talk to someone who also has Narcolepsy or is taking Provigil. Thanks!! *** F 19 3 months
11/13/2006
 3  insomnia doc prescribed to take to reset my sleep clock. I have to take it early in AM and then by the time I put the kids to bed and quiet the house, I should be ready to sleep. It works great for a normal person with the normal amount of stress but my stress and business still keeps me awale at night. I am falling asleep sometimes at 10 or 11 but only for about 1 hour. I wake up trembling and craving food. During days, I cannot eat after taking the med all day long. F 43 3 days
11/12/2006
 2  fatigue First 7 days WONDERFUL!! I was on cloud 9 after years of pain and fatigue, I felt like I was reborn! Then after the 7 days I went downhill ...no effect at all...went from 200mg daily to 250mg,started with head aches back pains,hand and feet pains. I was very disappointed....I thought I had found my wonder drug. Too affraid to go up to 300mg because of the side-effects. Too expensive....but if it had worked out for me I would have made sure I stayed with it. I'm glad it has helped many though. F 52 10 days
11/8/2006
 1  ADD Sleeplessness (Day 1), sweating, diarrhea, confusion, rambling, irritation, stopped working at day 5 At first it seemed to be working well, except by day 3 I noticed that it was the source of my confusion; I was mispronouncing words and had awful grammar. I assumed it would go away, so I continued to take it. Day 4 I was extremely irritated for no reason. Day 5 I didn't feel the drug at all and I was starting to feel depressed (i don't know if the provigil was the source of this, i am also bipolar). Day 6 took twice as much (200mg) still nothing. My motivation and attention is back where it was prior to taking this medication. F 21 6 days
11/6/2006
 2  Excessive Daytime Sleepiness At first, a little fidgity if I took too much. Increase in heart palpitations. Increase in migraines. After about 3 months I noticed an increasing general "misery", something like being seriously sleep deprived, and I began losing alertness and wakefulness during the day. The doctors recommended increasing the dosage from 100-200mg/day to 400-600/day. Instead I quit altogether to get a feel for my condition without the medication - to reassess. It was the best thing I've ever done. Heart palpitations are back to "occasional", not one migraine, and my daily misery is gone, just back to the "normal" EDS. F 45 3.5 months
10/31/2006
 2  Excessive Daytime Sleepiness At first, a little fidgity if I took too much. Increase in heart palpitations. After about 3 months I noticed an increasing general "misery", something like being seriously sleep deprived, and I began losing alertness and wakefulness during the day. The doctors recommended increasing the dosage from 100-200mg/day to 400-600/day. Instead I quit altogether to get a feel for my condition without the medication - to reassess. It was the best thing I've ever done. Heart palpitations are back to "occasional" and my daily misery is gone, just back to the "normal" EDS. F 45 3.5 months
10/31/2006
 4  daytime sleepiness At first, sore throat in the evenings (went away after a month or so). I get evening headaches from this drug. Does very much help with my "cotton for brains" caused by my NCS. M 40 3 months
10/29/2006
 2  excessive sleepiness sleepiness! terrible indigestion Worked great for first few weeks but have now developed almost intolerable feeling of fullness in upper abdomen a few hours after taking it, and sleepiness has returned but much worse. F 42 1 months
10/19/2006
 4  Severe ADHD Hard to tell. I was wondering if anyone else had experienced increased joint and muscle pain, but apparently not. I miss my VIOXX. My memory seems less acute. I find this far more effective, for me, than the standard psychotropics. Most of them were disastrous. I take a hefty dose in the morning, and it's really noticeable by late afternoon if I forget to take it. It makes a big difference to my focus and hence my mood. Without it, I'm incompetent, but this makes me worry a little about dependence. As it wears off in the evening, I become noticeably more fragile. M 54
10/15/2006
 5  apnea, fatigue, depression increased appetite, strong urine smell, sleep problems with higher dose, irritability after several consecutive days of taking it. i found the best results by taking provigil during my work week and refraining on the weekends. this seemed to prevent the onset of irritability i noticed after taking it for 10+ consecutive days. provigil has greatly increased my focus and performance and has greatly reduced the impact of my lifelong depression. it has helped tremendously where countless other antidepressants failed. M 41 5 months
10/10/2006
 4  Insomnia Headache (fixed with IBUPROFIN) More frequent bowel amovements. The first couple days I was incredibly happy and spunky, then it kind of wore down to a normal state. I feel much more awake, and the thing about the loss of appetite is very true. I have lost 10 lbs. in about 3 weeks. I do get the occassional jitter, but it really isn't bad enough for me to stop taking. I guess I am one of the lucky ones, my insurance actually covered it! F 22 3 weeks
9/25/2006
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 1  fatigue I am a recovering addict and became extremely addicted to provigil and ended up with life threatening abuse issues. I developed afibrillation of the heart and periphreal neuropathy. M 51
9/22/2006
 4  Narcolepsy I feel a slight lack of groundedness and awareness, similar to when I've had to much coffee but without jitters. Provigil gives me a stronger sense of motivation and I feel more task oriented and able to organize and function in my daily life. However, I feel as thought it blocks me form my real emotions. My urine smells funny too. I am an artist....a writer & composer. I consider myself an emotionally stable person, no depression, but I don't feel as in-touch with my feelings when taking provigil. It blocks all my emotions (somewhat) good and bad. ...Joy and laughter, spontaneity, sadness. My creative instincts feel slightly blocked. I take as little as possible. 1 200-mg pill about 30 minutes after I wake up. This stops my sleepy spells until late afternoon, then I manage the rest of my day with short naps. I don't take provigil on the weekends. I've experimented with not taking provigil for weeks at a time. I feel slightly unmotivated and a little sad for the first few days.....then I am fine...but have to battle my sleepiness. F 29 4 years
9/21/2006
 2  EDS related to sleep apnea Funny taste, blurred vision, headache, sloooow brain at times. Initial dosage no longer worked. Worked great the first week, then my vision became funny when looking at green colors. Kept me awake at first, then I would get drowsy like before. Tried Ritalin SR and that has been working fine. M 41 3 weeks
9/8/2006
 3  excessive sleepiness My ears have felt stopped up and loss of hearing, but not sure if it is from modalert (provigil) would like to know if anyone else has had this symptom while taking it. I took it for three months before symptoms were bad. other than that, no side effects and it helps me stay awake it is very expensive and my insurance would not cover it because I had not had enough sleep studies done, so I use generic, modalert by mail F 63 3 months
8/30/2006
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 1  Narcolepsy I"m a nurse and it made me "scatterbrained." Normally i'm an A1 nurse, but when I took provigil (granted I stopped after 1 week and went back to ritalin); I just couldn't stay on task...I almost felt "drunk". Not conducive to my line of work. toooooooo expensive, it was $200 for a 1 month supply before my health insurance changed and started picking up the cost F 43 7 days
8/20/2006
 5  Overcome Meth/Amphetamine addiction Nausea if I drink too much caffeine. Aweful urine smell. Difficulty sleeping all night. Usually wake up once a night. It's the best thing that's ever happened to me. I am productive at work, home and I am able to finally enjoy my family. I have regained control over my life and the respect of my family and co-workers. I haven't craved or used Meth or any other illegal substance and don't plan to. Thank goodness for Provigil, it has released me from my bondage and I might just be lucky enough to life longer than I would have if I hadn't been prescribed with this wonder drug. It's worth every penny. F 47 7 months
8/13/2006

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