PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Sleepiness, Lethargy Increase in migrane headaches from about one per month to about one or two per week. New pain in the eye sockets and behind the eyes. Heartburn. Stopped taking Provigil and head pain decreased right away. I'd rather feel tired than in a great deal of pain while taking Provigil. F 47 5 months
12/14/2005
 5  Fibromyalgia/Chronic Fatigue Initially, inability to sleep at night. Six to eight weeks after initial dose, began to notice weight loss but no real loss of appetite. Headache first few days then none. Some problems of concentration but cannot entirely attribute this to Provigil as this is also a symptom I have endured for many years due to Fibro. Expensive and not covered by most insurance. Living in constant pain as I do takes great energy leaving me spent and lacking energy for even the simplest daily tasks. Provigil has greatly increased my sense of having energy, but never extremely so. I take 200mg per day and currently rely on samples.May very well need to stop taking Provigil should that change. I dread return to life before Provigil. Although I still struggle daily with illness, Provigil has lessened some of the severity of my suffering. F 49 6 months
12/5/2005
 5  Narcolepsy Headache, nausea, little jitters the first few days. All wore off in a few weeks Provigil changed my life! I was failing college because I couldn't stay awake in any of my classes. Now, I am awake and can actually take notes. I went from a C student to getting As in all my classes. I also function much better at work. A positive side effect is it has diminished my appetite greatly. I was already trying to lose weight, I have lost an extra 30 pounds since I started Provigil. Best side effect of any medication I have every tried! F 22 3 months
11/30/2005
 3  narcolespy I've been on Provigil for about 2 months 600 mg. I have been experiencing ringing in one ear for about a month. Not sure if this is associated with the provigil, but did not notice this before taking the drug. My doctor started me off with 200 mg for 3 days; then went to 400 mg for additional 3 days, finally 600 mg daily. The medication seems to work better than Retalin for me,(15 mg 3xday) however, I find that I still get very lethargic after about 4 or 5 hours, if that long. Yawning is presistent. My eyes become droopy (have been asked by others if I'm ok) I'm not necessarily sleepy, but lethargic. Concerned that I'm taking such a high doseage and experiencing these issues. Has anyone else reported ringing in the ears? F 54 2 months
11/28/2005
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 4  chronic fatigue, apnea odor to urine, morning rush, insomnia if taken too late in the day, insomnia if taken with caffiene, weight loss, loss of appetite, abnormal bowel movements, unusually high heartrate. some of these symptoms slowly decreasing with time. definitely helps! i'm able to stay awake and feel alert much more during the day. i used to have such a hard time concentrating i couldn't read to study for school but now i'm able to. the side effects can be annoying sometimes and the drug is expensive but well worth it. F 19 21 days
11/20/2005
 5  sjogrens, sleep apnea strong urine, morning rush, hyper with too much coffee, must take sleeping aide. The first two week "rush" does become regular life. I love it. I feel like my life would not be worth living without it. I feel 20 years younger. My depression lifted. My weariness lifted. My joint and muscle pain stopped and my energy went from 0 to 100. My body is working on keeping up. F 41 1 months
11/13/2005
 5  Hypersomnolence Decreased fatigue Helped me a ton! I now wake up and feel like everyone else during the day, and have no twitchiness, little anxiety, or other side effectsthat caffiene, etc. have. I switched from Paxil to Effexor about a year ago, and everything seemed alright...but after awhile, I noticed that I was always increadibly tired. I went off to college that year, and failed / dropped half my classes because I needed 12-16 hours of sleep a day, and would still be exausted when I forced myself out of bed. Evidently this kind of reaction is a common effect of Effexor. I talked to my doctor after returning home for the summer, and he suggested a few things (in addition to Effexor, as everything but the fatigue was great with that drug). Ultimately, Provigil was the only thing that has worked. I am currently working at a job that requires about 13 hours a day, 6-7 days a week of work, and am only very slightly tired throughout the day. I take 300 milligrams about 5-6 hours before I want to wake up, and I have wa M 19 6 months
11/8/2005
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 4  ADD; sleepiness. Hypertention with increased dose. I feel no different on it except that my attention span is better and my mind is fresh all day long. You know sometimes at the end of the day your mind feels tired and you cant study anymore?! Well with provigil you dont get that feeling. Works wonders on the mind even if up all night you can study and be good to go next day. Since I found out about it I bought too much of it, since it wasnt too expensive compared to pharmacy prices. 200mg tabs and I have over 200. 100tabs for $120. Email me or call me 6122810345. M 23 7 days
10/29/2005
 4  Fibromyalgia diarrhea, some jaw pain. Loss of appetite. In the 1st week, I as jittery a somewhat quick temper and difficulty in going to sleep (all of these 1st week symptoms went away after a week or so). Take the pill early enough in the day so as not to interfere with sleep that evening. The first week I had incredible energy that I haven't experienced in 8 years. Started taking the med to help me concentrate for studies to pass a certifications test (I passed!) Extremely helpful with "FibroFog." Initially was prescribed gradually to work up to 4 times/day, but never needed to take more than 1/day. Now I only take when needed to concentrate (busy schedule that day, etc.) or when weather is continually stormy (bringing on FibroFog). F 44 6 days
10/25/2005
 4  Fatigue w/ joint pain Increased energy, better able to stay "on-task" (can a clean house be considered a side effect?) Slight constant headache that has eased up the longer I take it. Smelly urine. Increased appetite (I WOULD be the ONE person to gain weight on this drug.) Sleep at first was not restful, but it's getting better. I crash from 8ish - 10ish in the evening which may or may not be related to the drug. Provigil has been very helpful for me so far. The only thing I feel from this drug is a lot more motivation. I don't feel jittery or manic. I even still feel sleepy/tired at times but I can work through it. The first few days I felt VERY motivated but that has tapered off a bit. I still feel that it is effective but I have to get plenty of sleep at night. I'm a little fearful that it will not continue to work for me. F 28 2 weeks
10/22/2005
 5  Post Lyme disease EDS & yawning Took 1st dose at MD's office, noon after 42 ounces diet coke. Twitched-paced like a meth addict-laughed maniacally...slept sometime the next day. Had to learn how to balance caffeine and prvgl. sometimes clench teeth, not much. CAN PROVIGIL PRECIPITATE A MANIC EPISODE IN BIPOLAR DISORDER? I THINK YES! (and I love it sometimes)I think yes...The main adverse reaction comes monthly when I have to pay $215 for the pills..........better provigil than ephedra or meth! Battled lyme disease for 7 years. It is kind of like having MS, but with massive prolonged antibiotics lyme goes away and I got better. I was left with a brain that doesn't wake up fully some days and seems to shut down in the afternoon. I was only able to return to work 2-3 partial days a week, going home early to sleep or actually having a cot in my office and napping behind my desk. I have a problem with yawning...like episodes of yawning where it looks like (red, watery eyes)I haven't slept for weeks in spite of having 12 hours sleep and a nap. As an addiction counselor, it is not ok to yawn through my clients entire session(and look like I am coming down from meth). I spent my life waiting to sleep. I craved sleep and never was satiated. Sleep study went ok. I started on 100-200 mg daily, depending on how I felt. Now I am up to 200-400mg daily, averaging out at 300mg. I try to skip doses whenever I can in an effort to slow building tolerance.I hate being dependent, not addic F 45 2.5 years
10/21/2005
 5  fibromyalgia/fatigue/RA loss of appetite, slight anxiousness, diarrhea I have only taken this medication for 2 weeks so far but I already feel like a new person. This is the best I have felt in over 10 years. I have energy, I am waking up early although I keep forgetting to eat. I have absolutly no appetite! Will see about the weight loss and if this wonderful new feeling wears off. I am taking 200 mgs at 7am and 200 mgs at 11 am F 29 2 weeks
10/12/2005
 4  ADD smelly urine, sometimes skin is hypersensitive sometimes it seems like it works well, and other times it seems like I am taking a placebo and has no effects. Headaches occur sporadically, aspirin works on that, seems ridiculously expensive for what it does although the lack of jitteriness is a good thing, I have actually fallen asleep right after taking it sometimes! M 51 2 years
10/12/2005
 5  Chronic Fatigue Syndrome Smelly urine, can make it hard to sleep at night After years of trying a variety of medications to improve my chronic fatigue, my doctor finally perscribed me Provigil. I've found it to be a complete lifesaver and have gone from sleeping 16 hours a day and not being able to attend school to sleeping 9 or 10 hours a day and being able to attend a top ranked college. F 21 2 years
9/21/2005
 5  autoimmune dysfunction+ bad fatigue possible aggitation of existing head/neck ache on left side. urine smells different or strong when i do not keep well hydrated. i feel a little queasy sometimes, but nothing serious... initially jittery, (200 mg, so backed down to 100 mg)after 2 months, seems to level off. tried 200 mg today and feel fine, maybe a little "brighter". provigil has made a very positive impact on my life. i lost my health insurance due to this NIGHTMARE quagmire of autoimmune disease/dyfunctions, which is still in the process of being firmly diagnosed, (undifferentiated connective tissue disease, sjogrens, endocrine and central nervous system/ possible cardiac involvement, and God knows what else. i have varied and less typical symptoms) provigil is newer, expensive and basically clinically approved for narcolepsy only, so i am seeking patient assistance from NORD,(national assn. for rare disorders via cephalon; 203-744-0100) my rheumatologist initially prescribed it for me and i cannot afford it on my own. i am in the professional fitness industry, so the changes seen/symptoms felt in my body are quite visable to me more so than to health professionals that don't i don't look sick to them by comparison to other people in similar situations is what i keep hearing although pr.ovigil does not help with the chronic pain related to my c F 45 2.5 months
9/20/2005
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 5  Bipolar Disorder, Obstructive Apnea Increase in appatite, decrease in sex drive, addiction. I can no longer imagine going on with life without Provigil. Before, I mearly existed; now I'm ALIVE! Seems to enhance the effects of other meds, especially the benzodiazepines, and also seems to reinforce the positive effects of Paxil. All cognitive functions are enhanced, and I feel a lot more comfortable about operation of motor vehicles. Another benefit I've observed is that the pain reliving effects of my OxyContin is re-established, and I feel less addicted to this potent pain pill. Provigil is one among a number of other medications I take that has successfully managed the dysphoria and agitation I daily experienced for a period of 25 years that resulted from sleeping disorders compounded with the myriad of symptoms that define the profile of Manic-Depression. Anyone needing a no-nonsense approach to how I control needless daily agony should probably write to me. M 43 4 months
9/10/2005
 5  Excessive sleepiness Strong odor to urine Insomnia if taken too late in the day I feel that I am sometimes too hyper early in the morning, like I get a manic rush an hour after I take Provigil until mid-afternoon. I had been sleeping 12-16 hours every day until I found Provigil. I go to college so there is not a lot of room for excessive sleepiness when you have a ton of homework and extracurricular/social activities. I am finally able to stay up all day and I don't get as agitated or irritated as I do when I am on Adderall or other stimulants. For the last couple of years, it was like I was never fully awake but now I can finally feel what it is like not to be constantly tired. For once, I don't have to plan my entire day around my napping schedule and for that I am very grateful. I haven't found that it has increased my concentration at all, but at the same time I don't think it has decreased it either. F 20 4 months
9/8/2005
 4  Narcolepsia sudden anger(/euphoria/sadness)wore off after the first 3 weeks, nervous convulsion in lower eyelid wore off roughly after same time, light dry eyes and nose have occured after approx. 3 month, especially in the night and thus miserably coinciding with usual waking in the night it helped very much to stay awake over my critical periods over the day. I only take 100mg between 11 and 12 am when I need to be awake and alert between 12 am and 2 pm. Teh effect then usually lasts until 4 pm. I try not to take it too often during the week. I have the feeling it has affected my sex life , though not too dramatically. Who has similar problems with eyes/nose and how do you treat it? F 22 5 months
8/28/2005
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 2  narcolepsy yawning and fatigue after taking it. Sometimes I think it doesn't do anything! F 26 1 years
8/25/2005
 1  EDS, Insomnia Talkativeness, jitteryness, much worsened insomnia, hyperactivity, restlessness and behavior resembling the manic phase of bipolar disorder. One of the worst things that ever happened to me. The decision to take it is thoroughly regretted as it's the closest I've come to taking recreational drugs. Rather than cure my condition, provigil only worsened it. What's particularly maddening is the fact that it's extremely long acting, I'm still suffering from its effects over a year after taking it. It's wasted two years of my life and I would NEVER recommend this drug to anyone. M 22 6 months
8/22/2005

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