PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  chronic fatigue None whatsoever This drug may work well for some, but for me, at 200mg a day it was rather diappointing. I could hardly notice any effect at all. I would do just as well by drinking a cup of coffee or taking a caffeine pill. I probably ought to try a higher dose and see if that helps more. M 54 25 days
3/13/2007
 5  narcolepsy very slight headache at times It took a lifetime of hearing from doctors that my sleepiness was "normal" until I finally found someone who would listen, a sleep study confirmed narcolepsy, this is one of the few drugs where the side effects are barely noticeable, it has saved my life, literally, because I was having narcolepsy while driving, have never felt wired or other weird feelings while on the drug, I take it daily in the a.m. at 200 mg, no problem now with narcolopsy. I would recommend trying it for narcolepsy. M 56 6 years
3/10/2007
 2  mild narcolepsy Weird urine smell, loss of concentration and inability to focus at length on one thing, appetite suppressed, insomnia if taken in the pm I was prescribed this med for mild form of narcolepsy. I was never extremely sleepy during the day, but rather consistently tired. I did not notice a big change or benefit from the drug. I continued to have problems waking up for work, but wonder if its just motivation rather than sleep disorder, since I don't have same problem when on vacation. However, I have noticed big negative difference in my concentration level and memory. Considering going off drug as cons outweight pros. F 38 60 days
3/6/2007
 5  Narcolepsy; excessive sleepiness It made me hyper for the first two days but in a good way. It was more energy than I had experienced in years. I don't remember much else from the early symptoms. It is most effective for me when taken at the same time daily -- when I get up. If I take it too late it produces insomnia. Once I accidentally stopped taking it for a week or so and the effects were immediate -- extreme lethargy, sleepiness, vivid dreams. I thought I was coming down with something but it went away as soon as I restarted the medication. I have heard that it is not as effective for some people if they stop taking it and restart it again but this has not been the case for myself. I can honestly say that this drug has improved my life. I tell you in the utmost sobriety that without this drug I would not be able to function as a normal human being. I would not be able to perform my duties at work. I would not have been able to advance at my work. I owe where I am today and what I have accomplished in my professional life in part to taking this drug. F 23 1 years
2/27/2007
 5  Excessive Daytime Sleepiness Mild nervous foot taping, etc. Better sleep. This drug saved my life. I was sleeping 16-18 hours a day and the doctors could not figure out why. I saw an article on the internet about Provigil and I asked my doctor if I could try it. My employer was planning on putting me on disability the next week. That was over two years ago and I'm still working. I notice that I have a habit of moving my thumb in a cirlce on the TV remote. It drives my wife crazy, but not as much as the constant sleeping did. The only other negative is some mild teeth clenching. I definitely sleep better now that I am taking Provigil. I was diagnosed with sleep apnea, but the pumps didn't help. This did. I take one 200 mg tablet every morning. Before this drug I could not drive more than 15 minutes without being in danger of falling asleep at the wheel. That's all gone. Completely! I have my life back!!! M 60 2 years
2/21/2007
 4  Idiopathic Hypersomnia Decreased appetite, lost 8 lbs so far and its only be on it a month. Get very weak and shaky if I don't eat for a very long time. Dry mouth. Also, watch out for Caffeine! Provigil really seems to intensify the effects of caffeine. After drinking one cup of coffee I feel like I just drank 8 cups of coffee. Provigil works better if you take it at the same time each day and definitely take it in the morning! This might sound like common sense, but being a college student I have a different kind of schedule. Somedays I have early classes, somedays I don't. And the weekend is a whole other story. But I try my best to try and wake up at the same time everyday and take it. Also, watch out for Caffeine! Provigil really seems to intensify the effects of caffeine. After drinking one cup of coffee I feel like I just drank 8 cups of coffee. F 20 1 months
2/15/2007
 2  Chronic Fatigue Extreme tiredness after medication wore off, after about 6 hours. Worked great for the first six hours, then wore off and left me in an even more tired than before state. Lost its potency after 4-5 days in a row. I decided to switch to Ritalin LA. F 20 2 weeks
2/12/2007
 3  Sleep Apnea less drowsy M 11 months
2/5/2007
 4  CFS, EDS, extreme fatigue Softened bowels, slight stomach ache -- not much but I am on a low dose Really helps me feel more mentally alert so I can have a social life again but it doesn't change how tired my body is. F 28 1 months
2/3/2007
 3  Daytime sleepiness due to circadian I thought I had caught the flu the other day, until reading some of these reviews. I have diarhea, no appitite, chills, fever, headache, etc., however those seem to be an initial side effect. That, or I'm just sick. I worked out yesterday and got winded far too easily, and become winded walking up the stairs--but I've read some people reporting bronchial tightening, so again maybe it is the Provigil. I had a lousy headache the other night, and I usually don't get headaches very often. My mouth has been VERY dry, to the point where my lips are all dry and cracked, despite the fact that I drink prodigious amounts of water all day long. This isn't technically a side effect, but I've noticed the medicine is not as effective as it was when I began (2 weeks ago), and it seems to lose its effectiveness by about 3pm, at which point I crash, unrecoverably. I'll talk about this more in the next section. It worked well the first four days. I was taking 100 mg. I felt energetic, confident, productive, at a time of day I am never those things--morning. However, the strength of effect has subsided somewhat, so I think I will increase to a more common dosage (200mg) and will report back then. One thing I clearly noticed is the crash. I am not a morning person . . . hell, I'm not even a day person. I usually don't catch my first wind until 7pm. On the provigil however, I am a much more functional person during the first half of the day, until the crash in the mid-afternoon. At that point, you'd think I hadn't slept in days. That is weird for me, being a night person, and now being totally drained by 5pm. I teach an anatomy course, in the late evening, so this is also problematic for that reason as well. It seems provigil has given me the first half of the day, but taken away the second (and most productive) half. I'm not so sure that trade off is worth it. Perhaps 200mg will st M 32 2 weeks
2/1/2007
 5  Bipolar; Mental Fatigue Urine smelled funny, some clenching of the jaw, but may be from coffee Taking 200mg per day. When I take it I can actually go to work at 8am and get something done. When I first took it I was disappointed that it didn't have more of a buzz, but the longer I took it, the more I noticed my energy coming back, and that is buzz enough. M 36 10 days
1/30/2007
 5  horrible fatigue from Crohn's None. I have adrenal supression problems because I have been on Prednisone for Crohn's disease for over 20 years. Without Provigil I am almost tied down to my bed because I have zilch energy to do anything. It to me is certainly a morning medication because if taken too late, staying up all night may be the result. I take 100 or 200 mg almost daily. If I am planning to read and rest, I skip it. F 64 4 years
1/29/2007
 5  chronic fatigue syndrome Mild headache. It has also been the very best medication I have ever taken for depression! F 45 6 months
1/27/2007
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 3  weight loss was fine the first 2 days on the medicine, but on the 3rd day had major nausea and fever/chills, dizziness that lasted about 3 hours in the middle of the day. (???) im scared to take it again. F 29 4 days
1/27/2007
 5  Adult ADD, Chronic fatique The first couple days (200mg daily) felt great! No naps, concentration extended. After 10 days, back to naps in afternoon (although considerably shorter)and a "foginess" or a "heavy headed" feeling and minor, dull headache. So far I do feel better than without it. I may try 300mg daily. Anyone know how long (on average) it is supposed to stay in system? Maybe I take it too early, but was afraid to take it later due to fear of imsomnia at night. Will be gald to talk to anyone about this. F 36 10 days
1/26/2007
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 5  multiple sclerosis None. Just need to take it about 10-12 hours prior to going to bed. Love it. It has changed my life. I have been able to resume most activities. I can now stay up and attend evening events. I am able to work 40 hours a week again as an active Realtor. Can not get by without it. F 54 3 years
1/23/2007
 5  hypoxia/dsypnea weight loss; worked great at first at 200mg. but, now it seems not as effective. Have been on provigil 2 years now. Love it, but I can still fall directly to sleep turning on the TV F 53 2 years
1/19/2007
 5  sleep apnea, narcolepsy Taking 200 mg. Diarrhea; as soon as I eat, I'm off to the bathroom. I am grinding my teeth to the point that I've loosened a cap -- also pushing my tongue down and biting the sides of my mouth and tongue. Provigil has helped me immensely. Don't fall asleep driving or at work now. More alert. Now if I can just stop grinding and biting!! Any help? F 56 2 months
1/18/2007
 5  multiple sclerosis none Saved my life. I suffered from severe fatique. Provigil put the "bounce back in my step". Before taking it, I was losing interest in so many things in life. It has "perked" me up without any nasty side effects. I truely doubt that I would have the quality of life I have today. Without provigil, I doubt if I be as effective at my job (middle school teacher). I take 400 mg a day. I take one pill in am and one at around 2 pm. No problem sleeping-no weight change. A wonder drug! F 56 4 years
1/16/2007
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 5  I was tired all day long This medication works. I took it in rehab and did not notice anything. I tried it six months later while sober and it worked great.I feel awake and I have a much more positive outlook. This medication has had a profoundly positive affect on me. M 52 4 days
1/14/2007
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