PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  cronic fatigue-major depression im on another medication so its hard to seperate some side effects. The ones i can narrow down to this medication are; strong medicine smell in urine, major crash towards the end of the medication cycle. a very small weight gain, but i havent confirmed if it is a direct cause of the provigil or not. I was on adderall which was great, but would give me a stumach ache for a short time after each dose, and bad night sweats. We think it even messed with my blood levels. Without it though, i was at 0 function. After more then a year i was changed to provigil to see if it would be any better. It helpes me start my day..which was a god send. I do feel now, that i need to take a higher dose to get enough of an effect. Im going to be talkig to my doctor about that. Maybe I just need a higher dose, or maybe Im building up a tolerance. F 30 10 months
7/30/2006
 1  Chronic fatigue + degree exams ABSOLUTE NIGHTMARE!!! I'm still traumatised by my 4 days on provagil 3 months later!! Could not sleep for 4 nights. At all. Not just poor quality sleep but no sleep. Not even a minute. I also couldn't concentrate, my concentration was far worse than when I was simply exhausted. I was in a kind of manic daze. Also as it stopped me from sleeping, (until I would 'crash' perhaps at 10 a.m.) it created a dependency where I would have to take more to attend an exam/ revise that morning. I can't quite explain how 'out of it' I was on this medication, I had little recollection of conversations I'd had whilst on it, and diminished control over my behaviour. TERRIBLE as a study aid, as however 'productive' I was whilst on it (would manicly devour revision material) I could not recollect anything I'd 'learnt' whilst on it. The whole experience was like taking time out from my life, and entering some other strange and sinister realm. HIDEOUS HIDEOUS HIDEOUS. For me it was truly TERRIBLE. If your body or brain chemistry is at all reactive/ sensitive I would avoid this like the plague. It is thought to work on the hypothalamus of the brain which is the whole body's control centre. My own doctor (not one that prescribed prov) could see hormonal electrolyte and blood abnormalities months after. Also increased autonomic nervous system functions, perhaps 6 bowel movements a day,m drinking vast quantities of water, 8litres/day and increased colorific requirements - weak if ate under 3000 calories/ day. Also developed excess hair for first time within week of taking this, has not gone. I HATE provagil. As a teenager I experimented with recreational drugs (youthful folly and all that) From experience, this is FAR more unpleasant than any experience with cocaine, ectasy or skunk, and about on a par with the worst possible speed or mushroom trips. Truly terrifying experience. F 21 5 days
7/26/2006
 1  ADD/ Chronic fatigue + degree exams ABSOLUTE NIGHTMARE!!! I'm still traumatised by my 4 days on provagil 3 months later!! Could not sleep for 4 nights. At all. Not just poor quality sleep but no sleep. Not even a minute. I also couldn't concentrate, my concentration was far worse than when I was simply exhausted. I was in a kind of manic daze. Also as it stopped me from sleeping, (until I would 'crash' perhaps at 10 a.m.) it created a dependency where I would have to take more to attend an exam/ revise that morning. I can't quite explain how 'out of it' I was on this medication, I had little recollection of conversations I'd had whilst on it, and diminished control over my behaviour. TERRIBLE as a study aid, as however 'productive' I was whilst on it (would manicly devour revision material) I could not recollect anything I'd 'learnt' whilst on it. The whole experience was like taking time out from my life, and entering some other strange and sinister realm. HIDEOUS HIDEOUS HIDEOUS. For me it was truly TERRIBLE. If your body or brain chemistry is at all reactive/ sensitive I would avoid this like the plague. It is thought to work on the hypothalamus of the brain which is the whole body's control centre. My own doctor (not one that prescribed prov) could see hormonal electrolyte and blood abnormalities months after. Also increased autonomic nervous system functions, perhaps 6 bowel movements a day,m drinking vast quantities of water, 8litres/day and increased colorific requirements - weak if ate under 3000 calories/ day. Also developed excess hair for first time within week of taking this, has not gone. I HATE provagil. Truly terrifying experience. F 21 5 days
7/26/2006
 1  sleep issues dry mouth, nervous, goose bumps (chills), mouth sores, dizzy, pain in back, tight muscles, loss of appetite, irritability, swollen tounge, swollen inner cheeks, rambling (talking), pain in abdomen, swollen abdomen, loose bowels, gas, cloudy head I was not informed that I was not to take this drug wile on birth control (nuva ring) I was perscribed 200mg in the morning 200mg at 2pm. I made it thru three doses before going to my family doctor whom knew nothing about it, same goes for my OB and the neurologist who prescribed it. F 23 2 days
7/20/2006
 2  depression, fatigue more tired, sluggish, mind-mush, unable to get anything done, itchiness, diminished appetite (good for me!), heart palpitations morning alertness (good), then rebound effect....after a few minutes of alertness, it then felt like it sucked all the energy out of my brain, thereafter for the rest of the day. Taking an additionsal dosage (50mg a.m.) another 50 in afternoon only made me jittery and uncomfortable, and still sluggish. Feel better on my favorite drug: caffeine...... F 46 14 days
7/15/2006
 3  add my doctor said most pts need to take this only once per day upon waking. After about 5 hrs I had the "crash effect" - -extreme sleepiness, watery eyes, yawinging every two minutes that is common with the amphetamine I took. Provigil to my understanding is not an amphet. Then the first few days I took Provigil I awoke with a headache around 3AM. F 42 4 days
7/9/2006
 4  Chronic Fatigue/Fibromyalgia Difficulty Concentrating, Stomache Pain, Insomnia, Moodiness. Worked great first six months. Now after 1 year Provigil seems to have lost it's effectiveness. Increased dosage from 200mg daily to 400mg daily produced tiredness and a feeling of being unwell and moody along with muscle aches and bloating. First six months of treatment gave me my life back. Past six months not so good. Will discontinue taking Provigil for a time and most likely try again in a few months. No withdrawal with this medication. The cost of this medication is very high. Most insurance will not cover unless prescribed for narcolepsy or ADD. F 48 12 months
7/7/2006
 5  depression, fatigue occassional mild headache Thank you God! F 47 3 weeks
6/30/2006
 5  ADHD, Bi-Polar Sweating a lot if active, dehydration, soft stools. I read this page the first day I had the drug, because I wanted to see what people thought of it, and if it had side effects that made it too much of a risk, compared to the rewards. I didn't believe what the people had written about provigil, I thought the were working for the company, and just promoting the pill. I had never had any drug, that worked exactly like I was told it would, and not only that, but I was used to waiting two or more weeks for the pill to work, but this was advertised to me as working in about 20 minutes. I didn't buy it. This is a miricle pill, it does what it says it will do, and it does it faster than anything I've ever taken. I could not praise it enough, to do it justice, and could not convey how much gratitude I have for the doctor that suggested it to my doctor. This pill hasn't given me my life back, it's given me life for the first time in my life. I'm not kidding here, I thought I knew what being awake was, but now I know I was living in M 29 1 weeks
6/27/2006
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 5  SSRI apathy/tiredness from Prozac Side effects are dealable. However, I notice ringing in ears (tinnitus) and sort of an up and down effect. I take 200 mg 2X day in the am and early afternoon. Love the initial come on to the drug, but do come down after a 2-3 delightful period. At that point I want another one. There is a "crashed" feeling as the drug wears off. However, this drug does bring some of the excitement and edge back to life that I think all SSRI's take away, along with the process of eliminating whatever you took them for in the first place (in my case panic disorder and mild depression). I just started to notice an apathetic state on prozac and wanted to feel some kind of edge back that the Prozac took away. Provigil also seems to have a mood brightening effect. Provigil is quite expensive I have found a Canadian resource (jandrugs) that gets a generic made in Fiji that is more cost effective. I do notice that the more I take it, the less the effect to a slight degree Still works well, but some tolerance adjustment is involved. A GREAT drug though, and a wakeness agent that seems to have little down side helps a lot with my business in terms of focus etc M 50 4 months
6/23/2006
 4  Adrenal Failure, Fibromyalgia Weight Loss, Mild Insomnia. Anger at High Cost. Dosage of 200mg daily, one year now. There is a marked decrease in drug effectiveness. Cannot afford considering dosage increase. Insurance does not cover. This medication is VERY expensive. But hey! Insurance covers the likes of VIAGRA, but not a med like Provigil, which actually gives a person back ALL aspects of one's life. Idiot insurance companies. F 50 1 years
6/22/2006
 4  Fatigue from Rheumatoid Arthritis Slight headache Worked great for the first week. I take 200mg in the morning. Then I added a 200mg caffeine pill twice a day and it started working great again. I feel more alert, better able to concentrate, more active in the evenings. F 48 21 days
6/21/2006
 1  Narcolepsy Sleepiness I used to take it, and it worked great. I built up a tolerance I guess. I tried taking more, but that only made the sleepiness worse. F 20 1 months
6/21/2006
 1  ADHD perminent decreased ability for word recognition. Permiment loss of certain short term memory abilities. After only 2.5 months on this drug my word recognition and memory was partially destroyed. Over 6 years later it has not gotten any better, I still lose my train of though quite often and have much worse word recognition than before. M 27 10 weeks
6/20/2006
 5  Daytime drowsiness Strong urine odor; some anxiety. But it works so well, and has improved my life so much, the benefits far outweigh the negative side effects. The anxiety actually helps me make the day so much more productive. I only take it when I know I will be sitting in long and boring meetings, or when I know I have to keep especially alert while working on a project that involves a lot of reading. 200 mg seems to do it, sometimes 400 is needed. For me, I have to classify it as a "miracle drug." M 62 3 months
6/18/2006
 5  Excessive daytime sleepiness, 1.If I took it before breakfast, I noticed a slight appetite supressing effect. 2.Be careful until you are used to it....caffeine and provigil seem to have a synergistic effect. 3. It has a tiny mood elevating effect..or is it just that my brain is finally able to function? At first, I hated being dependent upon a drug to function, especially with my history of addiction. Then after being on it for almost 3 years, 200mg to 400mg daily as needed, I changed insurance and got cut off. No withdrawals. Just a return to my previous sleepiness and difficulty functioning. Complex thought/cognitive process (like required at work) are difficult while light conversation with a friend poses less of a problem. After 4 months of hell off it, I am on my second day allowed only 100mg by the new doc. My cognitive processes are pretty darn good for 6 hours. I start to fade after that. PROVIGIL HAS GIVEN ME BACK MY BRAIN AND MY LIFE. I only wish the new insurance had already approved it so I didn't have to depend upon samples. It is horrendously expensive. I had been spending $200 a month as my co-pay which was 1/5 my monthly wages. If I didn't, I might as well not work. It wakes up the part of my brain that I blame Lyme disease for damaging (my opinion). I F 46 3 years
6/11/2006
 5  narcolepsy Possible weight gain. Thats my question. Anyone have a wieght gain problem I've been taking 600 mg of provigil daily for years. I was found to have narcolepsy at the young age of 8. Trying many drugs prior to provigil. I have some side effects such as fatique and now I seem to be gaining a little weight. I am exremly satisfied with the drug overall. I do still take a nap daily at 3 or so for about 1 1/2 hours. If i didn't I would fall asleep anyway and not fuction for the rest of the evening if I would force myself to stay awake. I feel provigil changed my life. F 18 2 days
6/10/2006
 5  Narcolepsy None to speak of. I was diagnosed with narcolepsy when I was 16. I've tried Cylert and other ADD drugs, but they weren't much help. I'm still sleepy, but nothing like I was before. M 26 8 years
6/4/2006
 2  narcolepsy/excessive daytime sleepy dry eyes, dry mouth, blurred vision in mornings, eye inflammation (IOI) when I tried to increase the dosage from 200mg to 400mg for less than two weeks. back to 200mg for 2 months, just tried to increase dosage to 400mg again for less than a week, I start to feel pain behind the eyes. Hands/fingers weakness and stiffness seems increased. My energy level is lower than when I was on Cylert (took it for more than 20 years.) Most of the time I just want to sit or lie down and do nothing because I feel weak. On 200mg, I will need to go to bed before 8pm, many days I found myself in bed at 6pm. Although my eye doctors said the IOI I had have nothing to do with Provigil, but I don't believe it, especially reading many comments from people who have taken Provigil. F 46 2 years
5/14/2006
 2  Narcolepsy I am prone to migraines. This is my 4th day and the migraines have increased a tremendous amount. Nausea, vomiting, diarrhea, rigid neck and eye pain. Believe or not, after taking the Provigil it makes me sleepy...isn't it supposed to do the opposite??? I have been sleeping this whole weekend and it makes me feel sluggish - I have lost my motivation in doing any type of outing or projects... I don't know if this is the right medication for me. I will contact my doctor because I cannot take the side effect especially the intense headaches, vomiting and sleepiness after taking the pill, 200mg, first thing in the morning. F 47 4 days
5/14/2006

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